iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132199

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

WD repeat domain 17

Genbank Nucleotide ID

AAMC01021846

Gene Name

wdr17

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000002453.3	ENSXETT00000005241.3	ENSXETP00000005241.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.20e-53	175.1	584	623
UBD/Beta-Prp	1.50e-68	231.3	491	659

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd..tllvsGsdDgtikvWDlrtgvllk 37
           gHt++v++l + ++   ll+sGs+D ti+vWD+r+g++l 
   Q: 584  GHTAPVRGLMWnTEipYLLISGSWDYTIRVWDTRDGTCLD 623
           8**********85573668*******************86 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgk.ilvtgseDrtikvw..dlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqc 128
           +l++ ++h a+v  +++s++ k +++tg eD++++v+    s+ +++ +++gh+++v  +++sp     l sGs+d t+r+wd  ++ c
   Q: 491  VLHK-YKHPAAVFGCDWSQNNKdMIATGCEDKNVRVYylATSSDQPLKVFTGHTAKVFHVRWSPlREGILCSGSDDGTVRIWDYTQDAC 578
           4444.789999*****9988777**************88778999*******************666********************** PP
   S: 129  leetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdl 209
           ++ +lsgh++ v+++ ++ +   ll+sGs D t+r+Wd + g++l+t    h  +vy l+ ++n+ + ++s+s+d+tv+lw+l
   Q: 579  IN-VLSGHTAPVRGLMWNTEIpYLLISGSWDYTIRVWDTRDGTCLDTVYD-HGADVYGLTCHPNRpFTMASCSRDSTVRLWSL 659
           **.******************9**************************87.**************999*************98 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MSQVKQVGLL AAGCQPWNKD VCAASGDRFA YCATLAIYVY QLDHRYNEFK LRAIMSEHKK 60
TITAISWCPH NPDMFASASA DNLVIIWNVA EQKVVARLDS TKGMPASLSW CWNSADAVAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTCAAG TAAAGCAAGT TGGTCTTCTG GCCGCTGGAT GCCAGCCGTG GAACAAAGAT 60
GTCTGTGCTG CTAGTGGAGA CAGGTTTGCC TACTGTGCCA CGCTTGCAAT CTATGTGTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001190	Ailuropoda melanoleuca	84.86	0.00e+00	2345.00
IUUC-Apl-003326	Anas platyrhynchos	88.66	0.00e+00	2383.00
IUUC-Aca-004349	Anolis carolinensis	86.80	0.00e+00	2331.00
IUUC-Ame-011366	Astyanax mexicanus	63.24	0.00e+00	1535.00
IUUC-Bta-013275	Bos taurus	85.41	0.00e+00	2343.00
IUUC-Cja-018970	Callithrix jacchus	83.81	0.00e+00	2291.00
IUUC-Cfa-021237	Canis familiaris	84.13	0.00e+00	2314.00
IUUC-Cpo-021342	Cavia porcellus	79.87	0.00e+00	1537.00
IUUC-Cre-022569	Chlamydomonas reinhardtii	28.84	6.00e-82	299.00
IUUC-Csa-023687	Chlorocebus sabaeus	85.33	0.00e+00	2332.00
IUUC-Cho-024772	Choloepus hoffmanni	76.09	0.00e+00	753.00
IUUC-Csv-026021	Ciona savignyi	40.69	0.00e+00	1025.00
IUUC-Dre-028031	Danio rerio	85.48	0.00e+00	2282.00
IUUC-Dno-029369	Dasypus novemcinctus	81.24	0.00e+00	2145.00
IUUC-Dor-030645	Dipodomys ordii	81.50	0.00e+00	2212.00
IUUC-Ete-032530	Echinops telfairi	79.45	0.00e+00	2131.00
IUUC-Eca-034405	Equus caballus	85.43	0.00e+00	2337.00
IUUC-Eeu-035006	Erinaceus europaeus	82.69	0.00e+00	999.00
IUUC-Fca-035965	Felis catus	83.95	0.00e+00	2305.00
IUUC-Fal-037136	Ficedula albicollis	86.41	0.00e+00	2293.00
IUUC-Gmo-039293	Gadus morhua	78.84	0.00e+00	2025.00
IUUC-Gga-040931	Gallus gallus	85.56	0.00e+00	2277.00
IUUC-Gac-042493	Gasterosteus aculeatus	78.19	0.00e+00	2095.00
IUUC-Ggo-045540	Gorilla gorilla	85.66	0.00e+00	2346.00
IUUC-Hsa-046708	Homo sapiens	84.88	0.00e+00	2325.00
IUUC-Lch-050135	Latimeria chalumnae	87.28	0.00e+00	1811.00
IUUC-Loc-051730	Lepisosteus oculatus	88.66	0.00e+00	2377.00
IUUC-Laf-053743	Loxodonta africana	85.25	0.00e+00	2321.00
IUUC-Mcc-055590	Macaca mulatta	85.02	0.00e+00	2323.00
IUUC-Meu-056328	Macropus eugenii	72.69	0.00e+00	1296.00
IUUC-Mga-059877	Meleagris gallopavo	83.85	0.00e+00	2263.00
IUUC-Mmr-060756	Microcebus murinus	86.10	0.00e+00	2355.00
IUUC-Mdo-062749	Monodelphis domestica	86.02	0.00e+00	2347.00
IUUC-Mmu-063668	Mus musculus	81.35	0.00e+00	2248.00
IUUC-Mac-065050	Musa acuminata	26.60	1.00e-19	90.10
IUUC-Mpu-066856	Mustela putorius furo	83.63	0.00e+00	2268.00
IUUC-Mlu-067186	Myotis lucifugus	81.10	0.00e+00	2230.00
IUUC-Nle-070018	Nomascus leucogenys	84.57	0.00e+00	2319.00
IUUC-Ont-071482	Oreochromis niloticus	74.33	0.00e+00	1952.00
IUUC-Oan-073065	Ornithorhynchus anatinus	86.79	0.00e+00	1801.00
IUUC-Ocu-073786	Oryctolagus cuniculus	84.56	0.00e+00	2316.00
IUUC-Oga-088545	Otolemur garnettii	80.24	0.00e+00	2173.00
IUUC-Oar-090205	Ovis aries	84.40	0.00e+00	2292.00
IUUC-Ptr-091092	Pan troglodytes	84.80	0.00e+00	2325.00
IUUC-Pan-092430	Papio anubis	85.25	0.00e+00	2331.00
IUUC-Psi-093774	Pelodiscus sinensis	90.34	0.00e+00	2430.00
IUUC-Pfo-097414	Poecilia formosa	79.60	0.00e+00	2051.00
IUUC-Pab-097853	Pongo abelii	84.88	0.00e+00	2325.00
IUUC-Pca-100440	Procavia capensis	66.67	0.00e+00	684.00
IUUC-Pva-102838	Pteropus vampyrus	82.58	0.00e+00	2259.00
IUUC-Rno-104951	Rattus norvegicus	80.46	0.00e+00	2204.00
IUUC-Sha-107508	Sarcophilus harrisii	84.52	0.00e+00	2322.00
IUUC-Sar-113549	Sorex araneus	88.29	0.00e+00	1522.00
IUUC-Ssc-115753	Sus scrofa	83.17	0.00e+00	1792.00
IUUC-Tgu-117315	Taeniopygia guttata	86.10	0.00e+00	2306.00
IUUC-Tru-118153	Takifugu rubripes	78.16	0.00e+00	2061.00
IUUC-Tsy-119384	Tarsius syrichta	79.16	0.00e+00	2150.00
IUUC-Tni-120820	Tetraodon nigroviridis	85.19	2.00e-112	397.00
IUUC-Tbe-127579	Tupaia belangeri	71.75	0.00e+00	961.00
IUUC-Ttr-128488	Tursiops truncatus	77.28	0.00e+00	2085.00
IUUC-Vpa-130274	Vicugna pacos	82.33	0.00e+00	981.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence