iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053625

Ensembl Protein ID

ENSLAFP00000015411.3

UniProt Accession

G3TKP7; G3TKP7_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TNIP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000018389.3	ENSLAFT00000018390.3	ENSLAFP00000015411.3
ENSLAFG00000018389.3	ENSLAFT00000035230.1	ENSLAFP00000023132.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	1.00e-24	86.6	465	525

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndslkask 61
           k+el++++e+LkqQv+i++eDFq+ER+dREr+neekeeL++qveklq+qv+++n+++ka+k
   Q: 465  KQELITQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLSNAQIKAFK 525
           699*******************************************************986 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MEGRGPYRIY DPGGSVPPGE ASTAFERLVE ENSRLKEKMQ GIKMLGELLE ESQMEASRLR 60
QKAEELVKDS ELLQPPSSSL ASFDHLAELT DLDLPIILPQ CISDLVLTFA QRTDGDPSDK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAGGGA GAGGACCCTA CCGGATCTAC GACCCTGGGG GCAGCGTGCC TCCAGGAGAG 60
GCATCCACAG CTTTTGAGCG CCTAGTGGAG GAGAATTCCC GGCTGAAGGA AAAAATGCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR033372--TNIP1

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0009101--P:glycoprotein biosynthetic process
GO:0007159--P:leukocyte cell-cell adhesion
GO:0085032--P:modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade
GO:0002755--P:MyD88-dependent toll-like receptor signaling pathway
GO:0070373--P:negative regulation of ERK1 and ERK2 cascade
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050727--P:regulation of inflammatory response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002103	Ailuropoda melanoleuca	83.02	0.00e+00	816.00
IUUC-Apl-004176	Anas platyrhynchos	52.13	9.00e-148	516.00
IUUC-Aca-004362	Anolis carolinensis	55.71	6.00e-154	537.00
IUUC-Ame-011307	Astyanax mexicanus	38.85	2.00e-89	323.00
IUUC-Bta-012620	Bos taurus	78.97	0.00e+00	719.00
IUUC-Cja-018996	Callithrix jacchus	82.87	0.00e+00	887.00
IUUC-Cfa-020274	Canis familiaris	82.70	0.00e+00	818.00
IUUC-Cpo-021786	Cavia porcellus	79.28	0.00e+00	847.00
IUUC-Csa-023236	Chlorocebus sabaeus	83.64	0.00e+00	827.00
IUUC-Cho-024535	Choloepus hoffmanni	73.42	1.00e-47	184.00
IUUC-Cin-025355	Ciona intestinalis	24.11	1.00e-09	58.50
IUUC-Dre-028725	Danio rerio	44.10	1.00e-115	410.00
IUUC-Dno-028967	Dasypus novemcinctus	84.12	6.00e-102	363.00
IUUC-Dor-030761	Dipodomys ordii	78.98	7.00e-108	384.00
IUUC-Ete-032695	Echinops telfairi	71.58	0.00e+00	786.00
IUUC-Eca-033655	Equus caballus	82.70	0.00e+00	885.00
IUUC-Eeu-035335	Erinaceus europaeus	64.23	2.00e-98	353.00
IUUC-Fca-035597	Felis catus	84.43	0.00e+00	891.00
IUUC-Fal-037020	Ficedula albicollis	51.18	1.00e-138	486.00
IUUC-Gga-040812	Gallus gallus	50.93	3.00e-147	514.00
IUUC-Ggo-045345	Gorilla gorilla	82.24	0.00e+00	882.00
IUUC-Hsa-045785	Homo sapiens	83.18	0.00e+00	898.00
IUUC-Itr-048029	Ictidomys tridecemlineatus	79.91	0.00e+00	886.00
IUUC-Lch-049745	Latimeria chalumnae	50.82	5.00e-112	397.00
IUUC-Loc-052635	Lepisosteus oculatus	48.80	2.00e-134	472.00
IUUC-Mcc-055730	Macaca mulatta	83.64	0.00e+00	867.00
IUUC-Meu-056550	Macropus eugenii	65.22	9.00e-104	370.00
IUUC-Mpo-057394	Magnaporthe poae	34.00	1.60e-01	32.00
IUUC-Mtr-058001	Medicago truncatula	50.00	1.10e-01	29.60
IUUC-Mga-059948	Meleagris gallopavo	63.32	4.00e-66	244.00
IUUC-Mmr-060900	Microcebus murinus	81.25	0.00e+00	933.00
IUUC-Mdo-061805	Monodelphis domestica	66.72	0.00e+00	762.00
IUUC-Mmu-063749	Mus musculus	80.25	0.00e+00	796.00
IUUC-Mpu-065979	Mustela putorius furo	82.23	0.00e+00	900.00
IUUC-Mlu-067100	Myotis lucifugus	79.91	0.00e+00	844.00
IUUC-Nle-069667	Nomascus leucogenys	83.49	0.00e+00	877.00
IUUC-Opr-070478	Ochotona princeps	77.12	0.00e+00	853.00
IUUC-Ont-071777	Oreochromis niloticus	44.66	2.00e-104	373.00
IUUC-Oan-073239	Ornithorhynchus anatinus	63.11	0.00e+00	702.00
IUUC-Ocu-073879	Oryctolagus cuniculus	81.16	0.00e+00	815.00
IUUC-Oga-088900	Otolemur garnettii	83.91	0.00e+00	980.00
IUUC-Oar-089444	Ovis aries	76.51	0.00e+00	765.00
IUUC-Ptr-090641	Pan troglodytes	83.33	0.00e+00	900.00
IUUC-Pan-092283	Papio anubis	83.67	0.00e+00	865.00
IUUC-Psi-092967	Pelodiscus sinensis	51.39	1.00e-145	509.00
IUUC-Pma-094726	Petromyzon marinus	31.81	3.00e-49	189.00
IUUC-Pfo-096085	Poecilia formosa	43.19	3.00e-105	375.00
IUUC-Pab-097976	Pongo abelii	78.35	0.00e+00	849.00
IUUC-Pca-100215	Procavia capensis	79.17	0.00e+00	791.00
IUUC-Pva-102258	Pteropus vampyrus	78.14	0.00e+00	832.00
IUUC-Rno-105833	Rattus norvegicus	77.78	0.00e+00	752.00
IUUC-Sly-111729	Solanum lycopersicum	27.08	2.00e-04	42.00
IUUC-Stu-112653	Solanum tuberosum	24.43	6.00e-04	39.70
IUUC-Ssc-115652	Sus scrofa	77.04	0.00e+00	803.00
IUUC-Tgu-116648	Taeniopygia guttata	50.68	6.00e-125	441.00
IUUC-Tru-118455	Takifugu rubripes	42.83	6.00e-102	364.00
IUUC-Tbe-128129	Tupaia belangeri	79.53	6.00e-98	351.00
IUUC-Ttr-128305	Tursiops truncatus	75.47	0.00e+00	717.00
IUUC-Xtr-131842	Xenopus tropicalis	48.34	8.00e-123	434.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence