iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067735

Ensembl Protein ID

ENSMLUP00000005612.2

UniProt Accession

G1P6C1; G1P6C1_MYOLU

Genbank Protein ID

ENSMLUP00000005612

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02043288

Gene Name

BRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000006128.2	ENSMLUT00000006145.2	ENSMLUP00000005612.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-35	120.2	118	155
UBD/Beta-Prp	6.90e-55	186.4	221	477

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 118  GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 155
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 23   sllatgsrdgtikvwdvttgkl......lrslsgheaevt..avkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsls 101
           ++++++++dgt+  w+++ ++l      l+  ++  ++v+  + +fs  g +l+tgs+D++i+ +   +++++ +  l+ h+d+v s++
   Q: 221  RYMVSTGADGTVCFWQWDLESLkfsarpLKFTEKPRPGVQmlCSSFSVGGMFLATGSTDHVIRMYflGFEAPEKIAELESHTDKVDSIQ 309
           799***************999988977666667777777622556888888**************99999******************* PP
   S: 102  fspsgdklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl 175
           f+ +gd+++sGs+d t+r+w  e+ ++ +                 ++  +  v++++++++++++v++ +D ++++W++ tg+ll+ l
   Q: 310  FCNNGDRFLSGSRDGTARIWRFEQLEWRSIlldmatrisgdltseEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNL 398
           *************************99998999********988777777788************************************ PP
   S: 176  tgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
            g h d v  l+   fds  + ++s+++dg++ +wd+ +g+ ++ + +         v + +fs+++++++++ s+g + i+
   Q: 399  LG-HADEVFVLEthpFDS--RIMLSAGHDGSIFIWDVTKGTKMKHYFNMIegqghGAVFDCKFSQDGQHFACTDSHGHLLIF 477
           *9.*********555555..99****************999977766544444456677789999******99999998886 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

VLSNKHVAPD HLLQICQRIG PMLDKEIPPS ISRVTSLLGA GRQSLLRTAK DCRHTVWKGS 60
AFAALHRGRP PEMPVNYGYP PSLVEIHRGK QLTGCSTFST AFPGTMYQHI KMHRRILGHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTTGTCCA ATAAGCATGT GGCTCCTGAT CATCTGTTGC AAATCTGCCA GCGCATCGGT 60
CCCATGTTGG ATAAAGAAAT TCCACCCAGT ATTTCAAGAG TCACTTCTTT ACTTGGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002332	Ailuropoda melanoleuca	90.64	0.00e+00	3046.00
IUUC-Apl-004083	Anas platyrhynchos	59.60	0.00e+00	2002.00
IUUC-Bta-013217	Bos taurus	87.24	0.00e+00	3493.00
IUUC-Cja-019966	Callithrix jacchus	85.22	0.00e+00	3414.00
IUUC-Cfa-021037	Canis familiaris	87.30	0.00e+00	3470.00
IUUC-Cpo-021934	Cavia porcellus	89.77	0.00e+00	2558.00
IUUC-Csa-023352	Chlorocebus sabaeus	85.26	0.00e+00	3262.00
IUUC-Cho-024690	Choloepus hoffmanni	77.23	0.00e+00	1291.00
IUUC-Dno-028938	Dasypus novemcinctus	84.47	0.00e+00	3449.00
IUUC-Eca-034349	Equus caballus	88.30	0.00e+00	3509.00
IUUC-Fca-035485	Felis catus	85.64	0.00e+00	3049.00
IUUC-Ggo-045500	Gorilla gorilla	86.09	0.00e+00	3429.00
IUUC-Hsa-046350	Homo sapiens	86.04	0.00e+00	3435.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	92.02	0.00e+00	1063.00
IUUC-Lch-049662	Latimeria chalumnae	70.62	0.00e+00	1930.00
IUUC-Laf-053848	Loxodonta africana	85.01	0.00e+00	3379.00
IUUC-Mcc-054638	Macaca mulatta	85.69	0.00e+00	3418.00
IUUC-Meu-056739	Macropus eugenii	79.62	0.00e+00	1108.00
IUUC-Mga-060165	Meleagris gallopavo	75.91	0.00e+00	2147.00
IUUC-Mmr-061227	Microcebus murinus	86.62	0.00e+00	3477.00
IUUC-Mdo-062074	Monodelphis domestica	83.00	0.00e+00	2326.00
IUUC-Mmu-064075	Mus musculus	80.78	0.00e+00	2785.00
IUUC-Mpu-066643	Mustela putorius furo	90.31	0.00e+00	2958.00
IUUC-Nle-069402	Nomascus leucogenys	91.21	0.00e+00	2806.00
IUUC-Oan-072954	Ornithorhynchus anatinus	68.84	0.00e+00	2674.00
IUUC-Ocu-074456	Oryctolagus cuniculus	83.54	0.00e+00	3432.00
IUUC-Olu-087745	Ostreococcus lucimarinus	28.76	1.00e-56	215.00
IUUC-Oga-087938	Otolemur garnettii	79.65	0.00e+00	2971.00
IUUC-Oar-090214	Ovis aries	86.45	0.00e+00	3447.00
IUUC-Ptr-091213	Pan troglodytes	86.13	0.00e+00	3396.00
IUUC-Pan-092444	Papio anubis	84.90	0.00e+00	3397.00
IUUC-Pfo-097318	Poecilia formosa	61.42	0.00e+00	1656.00
IUUC-Pab-097573	Pongo abelii	84.81	0.00e+00	3326.00
IUUC-Pva-102782	Pteropus vampyrus	88.39	0.00e+00	3560.00
IUUC-Rno-105687	Rattus norvegicus	76.48	0.00e+00	3043.00
IUUC-Sar-113519	Sorex araneus	79.61	0.00e+00	1711.00
IUUC-Tsy-118921	Tarsius syrichta	87.32	0.00e+00	1894.00
IUUC-Tbe-127663	Tupaia belangeri	75.07	0.00e+00	1217.00
IUUC-Ttr-128561	Tursiops truncatus	84.64	0.00e+00	3254.00
IUUC-Vpa-130444	Vicugna pacos	84.39	0.00e+00	3226.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence