iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059283

Ensembl Protein ID

ENSMGAP00000007489.2

UniProt Accession

G1N635; G1N635_MELGA

Protein Name

Uncharacterized protein

Gene Name

KIF21A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000007272.2	ENSMGAT00000008264.2	ENSMGAP00000007489.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.60e-31	104.3	1343	1377
UBD/Beta-Prp	1.50e-55	188.2	1336	1576

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gH+ +v c++ +d+ll +Gs D t+kvW+l tg  
   Q: 1343 GHAKPVLCVDATDDLLFTGSKDRTCKVWNLVTGQE 1377
           899******9878*****************99976 PP

UBD/Beta-Prp

   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdlet.gqc 128
           +++ + +gh ++v +v+  +d  +l tgs+Drt kvw+l tg+ +++l gh ++v+s++++ +++ + + s  ++i+vwd++   +c
   Q: 1336 QCIYTAEGHAKPVLCVDATDD--LLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSIKYCNYTSLVFTVS-TSYIKVWDIRDsAKC 1419
           5588899************99..9**************************************765555544.88*******961577 PP
   S: 129  lee......................tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng 192
           +++                      + +g++  +n ++++p+g +l+++++  + vr+Wdlk+ +   +ltg h ++v +l++d+ +
   Q: 1420 VRTltssgqampgdvcsgstnrtvtIPAGEN-QINQIALNPTGtFLYAAAG--NSVRMWDLKRFQSTGKLTG-HLGPVMCLTVDRIS 1502
           777*********************8888887.6778899999978888776..68****************9.*********66655 PP
   S: 193  ...kelvsgsldgtvklwdlqtgecvrtlnght......dnvksvrfspnderlvsgssDgsiriWdlrsgdllkt 259
                +v+gs+d ++k++d+ +g        h+      d +  ++    ++ l sgs D+ i+ Wdl ++dll++
   Q: 1503 ngqDLIVTGSKDHYIKMFDVTEGALGSVSPTHNfepphyDGIEALAIM--GDNLFSGSRDNGIKKWDLAQKDLLQQ 1576
           554999***************887744444444444444999999999..999******************99986 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

CLSETEQTEI KAGISQIRPQ LAKEKIEGCH ICTSVTPGEP QVFLGKDKAF TFDYVFNIDS 60
QQEEIYIQCI EKLIEGCFEG YNATVFAYGQ FHSTRTCFWW LGFNVNKILE RILNLKRTVE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTTATCAG AAACTGAACA AACTGAGATA AAAGCTGGAA TTTCTCAGTA AGGAATTAGT 60
GAGGAATTAG GACACTCCTA CCTTTACAAC TTGTTAAAAA TTGTTCTTTT CTGTGAAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	83.41	0.00e+00	2653.00
IUUC-Apl-003353	Anas platyrhynchos	91.06	0.00e+00	2808.00
IUUC-Aca-004467	Anolis carolinensis	83.79	0.00e+00	2698.00
IUUC-Ame-011237	Astyanax mexicanus	64.93	0.00e+00	1960.00
IUUC-Bta-013485	Bos taurus	83.60	0.00e+00	2593.00
IUUC-Cja-019385	Callithrix jacchus	82.37	0.00e+00	2578.00
IUUC-Cfa-020986	Canis familiaris	84.10	0.00e+00	2625.00
IUUC-Cpo-022297	Cavia porcellus	81.67	0.00e+00	2535.00
IUUC-Csa-023685	Chlorocebus sabaeus	82.38	0.00e+00	2615.00
IUUC-Cho-024531	Choloepus hoffmanni	83.31	0.00e+00	986.00
IUUC-Cin-025160	Ciona intestinalis	46.15	1.00e-85	310.00
IUUC-Dno-029972	Dasypus novemcinctus	80.52	0.00e+00	2468.00
IUUC-Ete-032872	Echinops telfairi	70.55	0.00e+00	920.00
IUUC-Eca-033518	Equus caballus	83.41	0.00e+00	2637.00
IUUC-Fca-036197	Felis catus	83.91	0.00e+00	2625.00
IUUC-Fal-037534	Ficedula albicollis	91.21	0.00e+00	2779.00
IUUC-Gmo-039407	Gadus morhua	64.47	0.00e+00	1294.00
IUUC-Gga-040687	Gallus gallus	92.79	0.00e+00	2840.00
IUUC-Gac-041626	Gasterosteus aculeatus	66.47	0.00e+00	2106.00
IUUC-Ggo-044457	Gorilla gorilla	83.96	0.00e+00	2629.00
IUUC-Hsa-046372	Homo sapiens	83.31	0.00e+00	2638.00
IUUC-Lch-049786	Latimeria chalumnae	56.08	0.00e+00	1706.00
IUUC-Loc-052689	Lepisosteus oculatus	72.70	0.00e+00	2286.00
IUUC-Laf-054018	Loxodonta africana	80.67	0.00e+00	2461.00
IUUC-Mcc-055558	Macaca mulatta	83.25	0.00e+00	2635.00
IUUC-Meu-056080	Macropus eugenii	80.50	0.00e+00	914.00
IUUC-Mmr-060773	Microcebus murinus	82.87	0.00e+00	2542.00
IUUC-Mdo-062688	Monodelphis domestica	83.97	0.00e+00	2459.00
IUUC-Mmu-063997	Mus musculus	81.43	0.00e+00	2518.00
IUUC-Mpu-066354	Mustela putorius furo	83.28	0.00e+00	2612.00
IUUC-Mlu-067599	Myotis lucifugus	83.16	0.00e+00	2593.00
IUUC-Nle-069477	Nomascus leucogenys	83.25	0.00e+00	2633.00
IUUC-Opr-070188	Ochotona princeps	73.05	0.00e+00	1589.00
IUUC-Ont-071938	Oreochromis niloticus	67.78	0.00e+00	2091.00
IUUC-Oan-073055	Ornithorhynchus anatinus	82.11	0.00e+00	2430.00
IUUC-Ocu-074302	Oryctolagus cuniculus	81.14	0.00e+00	2553.00
IUUC-Ola-086604	Oryzias latipes	65.26	0.00e+00	2010.00
IUUC-Oga-088799	Otolemur garnettii	84.82	0.00e+00	2431.00
IUUC-Oar-089629	Ovis aries	82.61	0.00e+00	2572.00
IUUC-Pan-092214	Papio anubis	82.59	0.00e+00	2611.00
IUUC-Psi-093757	Pelodiscus sinensis	80.83	0.00e+00	2470.00
IUUC-Pfo-096978	Poecilia formosa	65.05	0.00e+00	1311.00
IUUC-Pab-097984	Pongo abelii	83.37	0.00e+00	2626.00
IUUC-Pca-101061	Procavia capensis	70.38	0.00e+00	1590.00
IUUC-Pva-102306	Pteropus vampyrus	82.25	0.00e+00	2524.00
IUUC-Rno-105354	Rattus norvegicus	80.85	0.00e+00	2492.00
IUUC-Sha-106938	Sarcophilus harrisii	82.58	0.00e+00	1677.00
IUUC-Ssc-115810	Sus scrofa	83.02	0.00e+00	2571.00
IUUC-Tgu-117076	Taeniopygia guttata	89.04	0.00e+00	2635.00
IUUC-Tru-118091	Takifugu rubripes	64.26	0.00e+00	1254.00
IUUC-Tsy-119020	Tarsius syrichta	82.72	0.00e+00	2610.00
IUUC-Tni-120813	Tetraodon nigroviridis	63.57	0.00e+00	1239.00
IUUC-Tbe-127494	Tupaia belangeri	72.39	0.00e+00	909.00
IUUC-Ttr-128393	Tursiops truncatus	77.54	0.00e+00	2365.00
IUUC-Vpa-130675	Vicugna pacos	71.83	0.00e+00	669.00
IUUC-Xtr-132829	Xenopus tropicalis	76.26	0.00e+00	2415.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence