iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053812

UUCD1 version

UUC-LoA-00175

Ensembl Protein ID

ENSLAFP00000004130.2

UniProt Accession

G3SV78; G3SV78_LOXAF

Protein Name

Uncharacterized protein

Gene Name

RNF135

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000004933.2	ENSLAFT00000004933.2	ENSLAFP00000004130.2
ENSLAFG00000004933.2	ENSLAFT00000031056.1	ENSLAFP00000021015.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.80e-09	36.7	21	64

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iC+  +++ p++lpCgH f+ +Cl   w   +  +++++ CP+Cr
   Q: 21   CIICRGLLDC-PVTLPCGHSFCSSCLkSLW--GSWAEKPRWACPTCR 64
           ********99.***************8666..5558**********8 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAGLDSGPAI PVWLNEDDLG CIICRGLLDC PVTLPCGHSF CSSCLKSLWG SWAEKPRWAC 60
PTCREGAPQK PPLRKNTLLQ DLADKYSRAV RELEEGGRGA GPELAPGPAP MLGPALCSIF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGGCT TGGACTCCGG CCCGGCCATC CCGGTGTGGC TGAACGAGGA CGACCTGGGC 60
TGCATCATCT GCCGCGGGCT GCTCGACTGC CCCGTTACGC TGCCCTGCGG CCACAGCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0043021--F:ribonucleoprotein complex binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0032728--P:positive regulation of interferon-beta production
GO:0045088--P:regulation of innate immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002251	Ailuropoda melanoleuca	71.47	2.00e-124	437.00
IUUC-Apl-003301	Anas platyrhynchos	47.03	3.00e-42	164.00
IUUC-Aca-004520	Anolis carolinensis	37.50	8.00e-38	149.00
IUUC-Bta-012846	Bos taurus	64.97	4.00e-144	504.00
IUUC-Cja-019096	Callithrix jacchus	70.31	7.00e-155	540.00
IUUC-Cfa-020135	Canis familiaris	60.92	1.00e-135	476.00
IUUC-Cpo-022042	Cavia porcellus	55.32	3.00e-119	421.00
IUUC-Csa-024154	Chlorocebus sabaeus	70.74	9.00e-166	576.00
IUUC-Cho-024619	Choloepus hoffmanni	67.43	4.00e-111	394.00
IUUC-Dre-027925	Danio rerio	42.74	3.00e-23	102.00
IUUC-Dno-028856	Dasypus novemcinctus	67.30	3.00e-146	511.00
IUUC-Eca-033795	Equus caballus	67.15	5.00e-146	510.00
IUUC-Eeu-035078	Erinaceus europaeus	60.55	1.00e-143	502.00
IUUC-Fca-035503	Felis catus	73.04	8.00e-86	309.00
IUUC-Fal-036914	Ficedula albicollis	48.85	7.00e-33	132.00
IUUC-Ggo-045197	Gorilla gorilla	72.58	1.00e-147	516.00
IUUC-Hsa-046550	Homo sapiens	71.99	3.00e-177	614.00
IUUC-Itr-049007	Ictidomys tridecemlineatus	61.92	2.00e-147	515.00
IUUC-Mcc-055777	Macaca mulatta	70.05	2.00e-166	578.00
IUUC-Meu-056473	Macropus eugenii	52.54	2.00e-48	186.00
IUUC-Mmr-061016	Microcebus murinus	70.97	5.00e-165	573.00
IUUC-Mmu-063129	Mus musculus	53.33	3.00e-117	414.00
IUUC-Mpu-065938	Mustela putorius furo	60.97	2.00e-134	471.00
IUUC-Mlu-067911	Myotis lucifugus	61.43	7.00e-137	480.00
IUUC-Opr-071118	Ochotona princeps	58.06	2.00e-85	308.00
IUUC-Oan-073277	Ornithorhynchus anatinus	38.61	1.00e-67	250.00
IUUC-Ocu-074512	Oryctolagus cuniculus	69.74	2.00e-116	411.00
IUUC-Oga-089086	Otolemur garnettii	68.91	1.00e-165	575.00
IUUC-Oar-089493	Ovis aries	71.55	9.00e-95	339.00
IUUC-Ptr-090466	Pan troglodytes	71.43	9.00e-171	592.00
IUUC-Pan-091817	Papio anubis	69.82	5.00e-166	577.00
IUUC-Psi-093151	Pelodiscus sinensis	37.46	3.00e-50	192.00
IUUC-Pab-098342	Pongo abelii	72.52	2.00e-176	611.00
IUUC-Pca-101052	Procavia capensis	64.71	2.00e-87	315.00
IUUC-Pva-103178	Pteropus vampyrus	72.64	8.00e-128	450.00
IUUC-Rno-105519	Rattus norvegicus	55.66	1.00e-118	420.00
IUUC-Ssc-115925	Sus scrofa	66.82	2.00e-158	551.00
IUUC-Tgu-116757	Taeniopygia guttata	49.62	1.00e-33	135.00
IUUC-Ttr-128972	Tursiops truncatus	55.29	6.00e-65	239.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence