iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048621

Ensembl Protein ID

ENSSTOP00000012850.2

UniProt Accession

I3MMR4; I3MMR4_ICTTR

Genbank Protein ID

ENSSTOP00000012850

Protein Name

DNA repair protein REV1

Genbank Nucleotide ID

AGTP01088878

Gene Name

REV1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000014323.2	ENSSTOT00000014347.2	ENSSTOP00000012850.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBM	2.60e-22	77.7	1011	1039

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBM

   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
           ++sqvDpeVf++LP+e+Q+E++a+++q++
   Q: 1011 AFSQVDPEVFAALPAELQKELKAAYEQRQ 1039
           59*************************98 PP

Organism

Ictidomys tridecemlineatus

Functional Description
(View)

Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.

Protein Sequence
(Fasta)

MRRGGWRKRA ENDGWEKWGG YMAAKVQKLE EQFRTDAALQ KDGTSSTIFS GVAIYVNGYT 60
DPSAEELRKL MMLHGGQYHV YYSRSKTTHI IATNLPNAKI KELKGEKVIR PEWIVESIKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGCGAG GTGGATGGAG GAAGCGAGCT GAAAATGATG GCTGGGAAAA ATGGGTGTGT 60
TTTAAAGAAT AAAAATATTT TTCATTCTTT TACCTTATAA TGTGGCTTAA GGCATAAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000375	Aegilops tauschii	31.06	2.00e-30	127.00
IUUC-Aml-001185	Ailuropoda melanoleuca	87.63	0.00e+00	2137.00
IUUC-Atr-002915	Amborella trichopoda	32.42	8.00e-84	305.00
IUUC-Apl-004054	Anas platyrhynchos	75.24	0.00e+00	1793.00
IUUC-Aca-004304	Anolis carolinensis	69.49	0.00e+00	1657.00
IUUC-Aly-005696	Arabidopsis lyrata	34.15	1.00e-85	311.00
IUUC-Ath-006893	Arabidopsis thaliana	35.14	2.00e-87	317.00
IUUC-Ago-007722	Ashbya gossypii	28.60	2.00e-40	160.00
IUUC-Acl-008347	Aspergillus clavatus	37.67	5.00e-88	319.00
IUUC-Afl-008444	Aspergillus flavus	35.80	5.00e-88	319.00
IUUC-Afu-008837	Aspergillus fumigatus	32.24	1.00e-86	314.00
IUUC-Ani-009188	Aspergillus nidulans	32.46	6.00e-94	338.00
IUUC-Ang-009866	Aspergillus niger	34.09	1.00e-100	360.00
IUUC-Aor-010107	Aspergillus oryzae	35.80	6.00e-88	318.00
IUUC-Ate-010359	Aspergillus terreus	32.82	2.00e-94	340.00
IUUC-Ame-010664	Astyanax mexicanus	49.70	0.00e+00	1111.00
IUUC-Bgr-012244	Blumeria graminis	30.35	6.00e-83	302.00
IUUC-Bta-013405	Bos taurus	80.07	0.00e+00	1815.00
IUUC-Bci-013849	Botrytis cinerea	31.53	2.00e-87	317.00
IUUC-Bdi-014066	Brachypodium distachyon	36.73	9.00e-86	311.00
IUUC-Bol-015544	Brassica oleracea	35.61	2.00e-89	323.00
IUUC-Bra-017792	Brassica rapa	34.17	1.00e-86	314.00
IUUC-Cel-018148	Caenorhabditis elegans	35.80	2.00e-82	300.00
IUUC-Cja-019742	Callithrix jacchus	76.66	0.00e+00	1517.00
IUUC-Cfa-020112	Canis familiaris	88.28	0.00e+00	2167.00
IUUC-Cpo-022152	Cavia porcellus	85.08	0.00e+00	2169.00
IUUC-Cre-022951	Chlamydomonas reinhardtii	28.87	2.00e-44	174.00
IUUC-Csa-023504	Chlorocebus sabaeus	88.68	0.00e+00	2182.00
IUUC-Cho-024780	Choloepus hoffmanni	66.79	0.00e+00	733.00
IUUC-Cin-025276	Ciona intestinalis	41.93	6.00e-112	397.00
IUUC-Csv-026283	Ciona savignyi	45.34	3.00e-114	405.00
IUUC-Cgl-026726	Colletotrichum gloeosporioides	30.95	2.00e-89	324.00
IUUC-Cne-027079	Cryptococcus neoformans	33.93	1.00e-77	285.00
IUUC-Cme-027346	Cyanidioschyzon merolae	26.12	2.00e-46	181.00
IUUC-Dre-028073	Danio rerio	50.19	0.00e+00	1107.00
IUUC-Dno-030038	Dasypus novemcinctus	81.98	0.00e+00	2009.00
IUUC-Dor-031100	Dipodomys ordii	84.79	0.00e+00	1563.00
IUUC-Dse-031310	Dothistroma septosporum	30.00	2.00e-86	314.00
IUUC-Dme-031991	Drosophila melanogaster	41.62	9.00e-113	401.00
IUUC-Ete-033082	Echinops telfairi	77.37	0.00e+00	1426.00
IUUC-Eca-033471	Equus caballus	86.92	0.00e+00	2127.00
IUUC-Eeu-034993	Erinaceus europaeus	84.75	0.00e+00	1415.00
IUUC-Fca-035367	Felis catus	87.21	0.00e+00	2067.00
IUUC-Fal-036973	Ficedula albicollis	74.82	0.00e+00	1731.00
IUUC-Fox-037677	Fusarium oxysporum	30.99	1.00e-88	321.00
IUUC-Fso-038252	Fusarium solani	30.89	3.00e-93	336.00
IUUC-Gmo-039669	Gadus morhua	51.09	0.00e+00	810.00
IUUC-Ggr-039988	Gaeumannomyces graminis	33.81	1.00e-86	314.00
IUUC-Gga-040423	Gallus gallus	75.55	0.00e+00	1790.00
IUUC-Gac-042134	Gasterosteus aculeatus	47.33	0.00e+00	978.00
IUUC-Gma-042929	Glycine max	30.58	8.00e-115	408.00
IUUC-Ggo-044528	Gorilla gorilla	89.00	0.00e+00	2175.00
IUUC-Hsa-046259	Homo sapiens	88.84	0.00e+00	2142.00
IUUC-Hvu-047139	Hordeum vulgare	35.73	9.00e-59	220.00
IUUC-Kpa-049169	Komagataella pastoris	29.64	1.00e-60	228.00
IUUC-Lch-050471	Latimeria chalumnae	66.02	0.00e+00	1556.00
IUUC-Lpe-050800	Leersia perrieri	33.73	9.00e-89	321.00
IUUC-Loc-052320	Lepisosteus oculatus	47.05	0.00e+00	937.00
IUUC-Lma-053149	Leptosphaeria maculans	28.15	4.00e-95	342.00
IUUC-Laf-053810	Loxodonta africana	82.38	0.00e+00	1962.00
IUUC-Mcc-055574	Macaca mulatta	89.31	0.00e+00	2137.00
IUUC-Meu-055945	Macropus eugenii	64.94	0.00e+00	1137.00
IUUC-Mor-057195	Magnaporthe oryzae	30.41	2.00e-89	323.00
IUUC-Mpo-057488	Magnaporthe poae	35.06	7.00e-87	315.00
IUUC-Mtr-057955	Medicago truncatula	37.21	5.00e-92	332.00
IUUC-Mla-059027	Melampsora laricipopulina	35.56	4.00e-81	295.00
IUUC-Mga-060156	Meleagris gallopavo	75.24	0.00e+00	1791.00
IUUC-Mvi-060398	Microbotryum violaceum	36.49	6.00e-83	302.00
IUUC-Mmr-061113	Microcebus murinus	89.15	0.00e+00	2177.00
IUUC-Mdo-063001	Monodelphis domestica	81.27	0.00e+00	1958.00
IUUC-Mmu-063180	Mus musculus	83.81	0.00e+00	2054.00
IUUC-Mac-065551	Musa acuminata	38.49	3.00e-54	206.00
IUUC-Mpu-066525	Mustela putorius furo	88.20	0.00e+00	2141.00
IUUC-Mlu-067877	Myotis lucifugus	85.17	0.00e+00	2070.00
IUUC-Nfi-068418	Neosartorya fischeri	32.19	2.00e-86	314.00
IUUC-Ncr-068648	Neurospora crassa	32.56	1.00e-89	325.00
IUUC-Nle-069959	Nomascus leucogenys	89.00	0.00e+00	2151.00
IUUC-Opr-070522	Ochotona princeps	82.13	0.00e+00	1178.00
IUUC-Ont-072293	Oreochromis niloticus	47.97	0.00e+00	812.00
IUUC-Oan-073519	Ornithorhynchus anatinus	77.47	0.00e+00	1890.00
IUUC-Ocu-074492	Oryctolagus cuniculus	84.49	0.00e+00	1954.00
IUUC-Oba-075567	Oryza barthii	32.89	3.00e-89	323.00
IUUC-Obr-076332	Oryza brachyantha	36.67	3.00e-86	313.00
IUUC-Ogl-077348	Oryza glaberrima	32.89	4.00e-89	323.00
IUUC-Ogu-078779	Oryza glumaepatula	32.74	5.00e-89	322.00
IUUC-Oin-079738	Oryza indica	30.43	1.00e-77	284.00
IUUC-Olo-080701	Oryza longistaminata	30.66	4.00e-78	286.00
IUUC-Ome-081708	Oryza meridionalis	33.23	5.00e-86	312.00
IUUC-Oni-082251	Oryza nivara	32.31	3.00e-86	313.00
IUUC-Opu-083528	Oryza punctata	32.24	3.00e-81	296.00
IUUC-Oru-084293	Oryza rufipogon	32.14	3.00e-84	306.00
IUUC-Osa-085549	Oryza sativa	32.89	7.00e-89	322.00
IUUC-Ola-086793	Oryzias latipes	49.07	0.00e+00	826.00
IUUC-Olu-087786	Ostreococcus lucimarinus	30.15	2.00e-61	229.00
IUUC-Oga-089006	Otolemur garnettii	88.07	0.00e+00	2148.00
IUUC-Oar-089597	Ovis aries	81.74	0.00e+00	1990.00
IUUC-Ptr-091520	Pan troglodytes	88.92	0.00e+00	2144.00
IUUC-Pan-092333	Papio anubis	88.84	0.00e+00	2115.00
IUUC-Psi-094004	Pelodiscus sinensis	77.15	0.00e+00	1850.00
IUUC-Pma-094128	Petromyzon marinus	53.87	3.00e-95	342.00
IUUC-Pno-094849	Phaeosphaeria nodorum	28.45	6.00e-82	299.00
IUUC-Ppa-095714	Physcomitrella patens	36.88	7.00e-91	328.00
IUUC-Pfo-096569	Poecilia formosa	47.03	0.00e+00	993.00
IUUC-Pab-097960	Pongo abelii	88.60	0.00e+00	2138.00
IUUC-Pop-098921	Populus trichocarpa	36.12	2.00e-84	307.00
IUUC-Pca-100509	Procavia capensis	68.05	0.00e+00	1161.00
IUUC-Ppe-101730	Prunus persica	30.70	1.00e-90	327.00
IUUC-Pva-102142	Pteropus vampyrus	84.29	0.00e+00	2025.00
IUUC-Pgr-103446	Puccinia graminis	31.17	7.00e-69	255.00
IUUC-Ptt-103849	Puccinia triticina	30.29	6.00e-71	263.00
IUUC-Pte-104128	Pyrenophora teres	31.34	1.00e-85	311.00
IUUC-Pyt-104754	Pyrenophora triticirepentis	32.28	8.00e-85	308.00
IUUC-Rno-104871	Rattus norvegicus	80.96	0.00e+00	1995.00
IUUC-Sce-106236	Saccharomyces cerevisiae	27.64	2.00e-41	164.00
IUUC-Sha-106962	Sarcophilus harrisii	81.00	0.00e+00	1948.00
IUUC-Sja-107691	Schizosaccharomyces japonicus	32.15	3.00e-62	233.00
IUUC-Spo-108170	Schizosaccharomyces pombe	35.74	2.00e-65	243.00
IUUC-Ssl-108668	Sclerotinia sclerotiorum	32.45	1.00e-87	318.00
IUUC-Smo-109554	Selaginella moellendorffii	32.15	2.00e-85	310.00
IUUC-Sit-110479	Setaria italica	42.05	4.00e-70	259.00
IUUC-Sly-111752	Solanum lycopersicum	37.76	1.00e-89	324.00
IUUC-Sar-113304	Sorex araneus	85.32	0.00e+00	2026.00
IUUC-Sbi-114196	Sorghum bicolor	42.38	4.00e-71	263.00
IUUC-Sre-115151	Sporisorium reilianum	31.72	5.00e-85	309.00
IUUC-Ssc-116104	Sus scrofa	84.62	0.00e+00	2072.00
IUUC-Tgu-117438	Taeniopygia guttata	75.47	0.00e+00	1776.00
IUUC-Tru-118553	Takifugu rubripes	46.78	0.00e+00	990.00
IUUC-Tsy-119056	Tarsius syrichta	85.11	0.00e+00	2008.00
IUUC-Tni-119933	Tetraodon nigroviridis	46.29	0.00e+00	950.00
IUUC-Tca-121376	Theobroma cacao	33.96	1.00e-85	311.00
IUUC-Tre-121972	Trichoderma reesei	27.80	3.00e-85	310.00
IUUC-Tvi-122342	Trichoderma virens	31.27	2.00e-81	297.00
IUUC-Tae-123898	Triticum aestivum	32.94	3.00e-89	323.00
IUUC-Tur-126735	Triticum urartu	26.12	3.00e-36	147.00
IUUC-Tme-126999	Tuber melanosporum	33.33	9.00e-81	295.00
IUUC-Tbe-127280	Tupaia belangeri	87.30	8.00e-139	488.00
IUUC-Ttr-129104	Tursiops truncatus	85.50	0.00e+00	2049.00
IUUC-Uma-129562	Ustilago maydis	31.03	1.00e-87	318.00
IUUC-Vda-129862	Verticillium dahliae	30.66	4.00e-91	329.00
IUUC-Vpa-130819	Vicugna pacos	82.46	0.00e+00	1071.00
IUUC-Vvi-131111	Vitis vinifera	35.39	8.00e-86	311.00
IUUC-Xtr-132629	Xenopus tropicalis	61.64	0.00e+00	1402.00
IUUC-Xma-134065	Xiphophorus maculatus	50.70	0.00e+00	785.00
IUUC-Yli-134633	Yarrowia lipolytica	33.40	5.00e-65	243.00
IUUC-Zma-135176	Zea mays	36.86	1.00e-87	318.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence