iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022215

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02032054

Gene Name

TBL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000008889.3	ENSCPOT00000008969.2	ENSCPOP00000007984.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-23	81.8	86	119
UBD/Beta-Prp	5.90e-43	147.1	72	306

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H++ ++c++f s+ ++l++++dD t+++W+++++
   Q: 86   HSGNISCMDFsSNgKYLATCADDRTVRIWSTKDF 119
           9**********777***************98775 PP

UBD/Beta-Prp

   S: 37   wdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls....tgkcvhtlkghedsvlslsfspsg.dklvsGshdrtirv 120
           +++t   l + l++h++ +++++fs++gk+l+t+++Drt+++w+ +         +  + + d +++++fsp+   ++v   + +t+rv
   Q: 72   HNFTHRLLAAALKSHSGNISCMDFSSNGKYLATCADDRTVRIWSTKdflqREHRSMRANVELDHATLVRFSPDCrAFIVWLANGDTLRV 160
           566777778999*******************************7773433333333344678999*******655************** PP
   S: 121  wdletgqclee........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsld 201
           +++++++            + ++h++ v  + + ++g+ ++++s D+t+ +W+l  g++l t   ++ + +y   +++ +++++s++  
   Q: 161  FKMSKREDGGFtftatpedFPKKHKAPVINIGIADTGKFIMTASSDTTIIIWNL-KGQVLSTINTNQMNNIYAA-ISPCSRFVASCGFT 247
           ***9998765578889999***********************************.7888888877799999976.567789******** PP
   S: 202  gtvklwdlqtgec........vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlr 252
            +vk+w++  g+           +l+gh++ v + +fs+++ r++s+s+Dg+ ++Wd++
   Q: 248  PDVKIWEVCFGKKgefqevvrAFELKGHSAAVHCFAFSNDSRRMASVSKDGTWKLWDTD 306
           ********944444447777788999******************************865 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MDFRAVWELV VLSLLVGLLA LVATAAVARG WLRAEEKKGS QPVAQKTNEP KKPGSKKQKQ 60
QQRIRKEKPQ QHNFTHRLLA AALKSHSGNI SCMDFSSNGK YLATCADDRT VRIWSTKDFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACTTTC GGGCGGTGTG GGAGTTGGTG GTGCTGTCCC TGCTGGTCGG GCTGCTGGCC 60
CTCGTGGCGA CGGCGGCAGT GGCGCGGGGA TGGCTGCGCG CCGAGGAGAA GAAGGGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0003723--F:RNA binding
GO:0042149--P:cellular response to glucose starvation
GO:0071456--P:cellular response to hypoxia
GO:0030968--P:endoplasmic reticulum unfolded protein response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000109	Aegilops tauschii	31.82	2.00e-22	98.60
IUUC-Aml-002212	Ailuropoda melanoleuca	91.26	0.00e+00	712.00
IUUC-Atr-002903	Amborella trichopoda	29.22	1.00e-36	147.00
IUUC-Apl-003635	Anas platyrhynchos	74.39	1.00e-164	572.00
IUUC-Aca-004472	Anolis carolinensis	74.81	2.00e-167	581.00
IUUC-Aly-005761	Arabidopsis lyrata	30.57	7.00e-39	154.00
IUUC-Ath-007476	Arabidopsis thaliana	30.36	8.00e-39	154.00
IUUC-Ame-011221	Astyanax mexicanus	66.86	6.00e-148	517.00
IUUC-Bta-013186	Bos taurus	87.08	0.00e+00	714.00
IUUC-Bdi-014298	Brachypodium distachyon	30.35	4.00e-39	155.00
IUUC-Bol-015192	Brassica oleracea	29.10	1.00e-36	147.00
IUUC-Bra-017078	Brassica rapa	29.66	1.00e-37	150.00
IUUC-Cel-018602	Caenorhabditis elegans	31.91	1.00e-57	216.00
IUUC-Cja-018909	Callithrix jacchus	86.40	0.00e+00	689.00
IUUC-Cfa-020970	Canis familiaris	89.23	0.00e+00	723.00
IUUC-Cre-022949	Chlamydomonas reinhardtii	37.50	6.00e-21	93.20
IUUC-Csa-023530	Chlorocebus sabaeus	85.44	0.00e+00	706.00
IUUC-Cho-024598	Choloepus hoffmanni	92.47	3.00e-135	474.00
IUUC-Cin-025486	Ciona intestinalis	48.37	2.00e-105	376.00
IUUC-Csv-025930	Ciona savignyi	47.15	2.00e-96	345.00
IUUC-Dre-027507	Danio rerio	67.14	4.00e-149	521.00
IUUC-Dno-029726	Dasypus novemcinctus	86.60	0.00e+00	715.00
IUUC-Dor-030501	Dipodomys ordii	78.31	1.00e-178	619.00
IUUC-Ete-032794	Echinops telfairi	86.13	4.00e-131	460.00
IUUC-Eca-033982	Equus caballus	88.28	0.00e+00	674.00
IUUC-Eeu-035090	Erinaceus europaeus	87.73	1.00e-134	473.00
IUUC-Fca-035944	Felis catus	89.47	0.00e+00	741.00
IUUC-Fal-036992	Ficedula albicollis	66.93	7.00e-151	526.00
IUUC-Gmo-038710	Gadus morhua	65.63	7.00e-148	516.00
IUUC-Gga-040885	Gallus gallus	70.46	3.00e-116	410.00
IUUC-Gac-041922	Gasterosteus aculeatus	66.40	5.00e-154	537.00
IUUC-Gma-044233	Glycine max	30.61	5.00e-37	148.00
IUUC-Ggo-045172	Gorilla gorilla	87.70	0.00e+00	683.00
IUUC-Hsa-045711	Homo sapiens	85.20	0.00e+00	702.00
IUUC-Itr-048196	Ictidomys tridecemlineatus	91.57	0.00e+00	737.00
IUUC-Lch-049739	Latimeria chalumnae	71.17	5.00e-163	566.00
IUUC-Lpe-050795	Leersia perrieri	26.59	4.00e-23	102.00
IUUC-Loc-052113	Lepisosteus oculatus	73.26	5.00e-154	537.00
IUUC-Laf-053751	Loxodonta africana	85.58	0.00e+00	719.00
IUUC-Mcc-055022	Macaca mulatta	85.68	0.00e+00	696.00
IUUC-Meu-056003	Macropus eugenii	72.90	4.00e-162	563.00
IUUC-Mtr-058500	Medicago truncatula	30.11	1.00e-35	144.00
IUUC-Mga-059278	Meleagris gallopavo	69.94	1.00e-127	449.00
IUUC-Mmr-061148	Microcebus murinus	90.34	0.00e+00	702.00
IUUC-Mdo-063002	Monodelphis domestica	70.47	1.00e-158	552.00
IUUC-Mmu-063607	Mus musculus	90.80	0.00e+00	731.00
IUUC-Mac-065359	Musa acuminata	27.96	3.00e-37	149.00
IUUC-Mpu-066323	Mustela putorius furo	82.35	1.00e-171	595.00
IUUC-Mlu-067946	Myotis lucifugus	89.23	0.00e+00	736.00
IUUC-Nle-069019	Nomascus leucogenys	84.96	0.00e+00	697.00
IUUC-Opr-071047	Ochotona princeps	85.65	0.00e+00	686.00
IUUC-Ont-071694	Oreochromis niloticus	68.88	3.00e-152	531.00
IUUC-Oan-073474	Ornithorhynchus anatinus	56.16	1.00e-100	360.00
IUUC-Ocu-074493	Oryctolagus cuniculus	87.08	0.00e+00	684.00
IUUC-Oba-075468	Oryza barthii	27.70	1.00e-35	144.00
IUUC-Obr-076681	Oryza brachyantha	28.90	9.00e-37	147.00
IUUC-Ogl-077870	Oryza glaberrima	27.70	1.00e-35	144.00
IUUC-Ogu-078536	Oryza glumaepatula	27.70	1.00e-35	144.00
IUUC-Oin-080175	Oryza indica	27.70	1.00e-35	144.00
IUUC-Olo-080796	Oryza longistaminata	28.83	1.00e-33	137.00
IUUC-Oni-082076	Oryza nivara	27.70	1.00e-35	144.00
IUUC-Opu-083267	Oryza punctata	28.53	1.00e-35	144.00
IUUC-Oru-084553	Oryza rufipogon	27.70	2.00e-35	143.00
IUUC-Osa-085389	Oryza sativa	27.70	1.00e-35	144.00
IUUC-Ola-086414	Oryzias latipes	66.57	2.00e-149	522.00
IUUC-Oga-088656	Otolemur garnettii	85.89	0.00e+00	708.00
IUUC-Oar-089719	Ovis aries	90.55	0.00e+00	699.00
IUUC-Ptr-091087	Pan troglodytes	85.44	0.00e+00	706.00
IUUC-Pan-091709	Papio anubis	86.16	0.00e+00	711.00
IUUC-Psi-093265	Pelodiscus sinensis	71.50	5.00e-168	583.00
IUUC-Pma-094482	Petromyzon marinus	61.40	6.00e-60	223.00
IUUC-Ppa-095365	Physcomitrella patens	29.13	2.00e-39	156.00
IUUC-Pfo-097494	Poecilia formosa	67.14	1.00e-150	526.00
IUUC-Pab-098362	Pongo abelii	85.20	0.00e+00	702.00
IUUC-Pop-099163	Populus trichocarpa	29.45	4.00e-32	132.00
IUUC-Pca-101019	Procavia capensis	85.19	2.00e-149	522.00
IUUC-Ppe-102101	Prunus persica	29.32	2.00e-39	157.00
IUUC-Pva-102849	Pteropus vampyrus	90.00	0.00e+00	695.00
IUUC-Rno-105511	Rattus norvegicus	90.31	0.00e+00	715.00
IUUC-Sha-107265	Sarcophilus harrisii	68.12	3.00e-168	584.00
IUUC-Smo-108866	Selaginella moellendorffii	32.52	2.00e-36	146.00
IUUC-Sit-110806	Setaria italica	28.61	5.00e-35	142.00
IUUC-Sly-110994	Solanum lycopersicum	29.10	1.00e-36	147.00
IUUC-Stu-112493	Solanum tuberosum	36.98	6.00e-32	130.00
IUUC-Sar-113628	Sorex araneus	84.96	0.00e+00	682.00
IUUC-Sbi-114397	Sorghum bicolor	29.47	7.00e-37	148.00
IUUC-Ssc-116418	Sus scrofa	87.74	0.00e+00	733.00
IUUC-Tgu-117054	Taeniopygia guttata	67.55	1.00e-154	539.00
IUUC-Tru-118504	Takifugu rubripes	67.80	7.00e-162	563.00
IUUC-Tni-120254	Tetraodon nigroviridis	66.75	6.00e-160	556.00
IUUC-Tca-121085	Theobroma cacao	30.75	3.00e-37	149.00
IUUC-Tae-124320	Triticum aestivum	29.39	3.00e-38	152.00
IUUC-Tur-126756	Triticum urartu	27.17	6.00e-33	134.00
IUUC-Tbe-127903	Tupaia belangeri	83.93	0.00e+00	676.00
IUUC-Ttr-129118	Tursiops truncatus	86.60	0.00e+00	724.00
IUUC-Vvi-131125	Vitis vinifera	29.53	7.00e-37	147.00
IUUC-Xtr-132287	Xenopus tropicalis	74.79	7.00e-164	570.00
IUUC-Xma-134246	Xiphophorus maculatus	67.44	1.00e-150	526.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence