iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000020384.1	ENSONIT00000025707.1	ENSONIP00000025686.1
ENSONIG00000020384.1	ENSONIT00000025708.1	ENSONIP00000025687.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.40e-49	165.9	13	153

Active Site

Position(s)	Description	Evidence
93	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk... 87
           l+ elk+l+++p+eg+++++v+esdl++wev+i+Gp++t Yegg+Fk++i+fp dYP++PP+++fltk++hPn+yenG+vC+sil+   
   Q: 13   LMMELKSLQEQPVEGFRITLVEESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPVDYPYSPPTFRFLTKMWHPNIYENGDVCISILHppv 101
           689**********************************************************************************9999 PP
   S: 88   ........eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
                   ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ +++k+r 
   Q: 102  ddpqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMFRKWRD 153
           99999*9*************************************99998875 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MAHQSTPSSQ KALMMELKSL QEQPVEGFRI TLVEESDLYN WEVAIFGPPN TLYEGGYFKA 60
HIKFPVDYPY SPPTFRFLTK MWHPNIYENG DVCISILHPP VDDPQSGELP SERWNPTQNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCACAGCCAG GTTAGCATGG ACAGCCAATG AGTTTACCCT GCAGGGCTCA GCTGTAAGGA 60
AGCGAACACA CAGTGCAAGG AGACAGAGGT AAACACTTTC TGTTAACTTT GCTTTTTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003563	Anas platyrhynchos	93.06	1.00e-80	291.00
IUUC-Aca-004589	Anolis carolinensis	92.00	5.00e-111	393.00
IUUC-Ame-011300	Astyanax mexicanus	79.62	9.00e-115	405.00
IUUC-Bta-012968	Bos taurus	94.12	2.00e-106	378.00
IUUC-Cel-018460	Caenorhabditis elegans	66.14	5.00e-74	270.00
IUUC-Cja-018764	Callithrix jacchus	92.50	1.00e-111	395.00
IUUC-Cfa-020955	Canis familiaris	92.50	1.00e-111	395.00
IUUC-Cpo-021451	Cavia porcellus	92.50	1.00e-111	395.00
IUUC-Csa-024239	Chlorocebus sabaeus	92.50	1.00e-111	395.00
IUUC-Cho-024999	Choloepus hoffmanni	80.00	2.00e-25	109.00
IUUC-Cin-025257	Ciona intestinalis	70.50	4.00e-85	307.00
IUUC-Csv-025954	Ciona savignyi	71.50	5.00e-86	310.00
IUUC-Dre-028153	Danio rerio	94.97	6.00e-114	403.00
IUUC-Dno-029368	Dasypus novemcinctus	94.12	2.00e-106	378.00
IUUC-Dor-030686	Dipodomys ordii	92.50	1.00e-111	395.00
IUUC-Dme-032106	Drosophila melanogaster	74.87	4.00e-88	317.00
IUUC-Ete-033001	Echinops telfairi	93.75	7.00e-60	222.00
IUUC-Eca-034221	Equus caballus	93.71	7.00e-80	289.00
IUUC-Fca-036381	Felis catus	93.10	2.00e-80	291.00
IUUC-Fal-037135	Ficedula albicollis	92.50	4.00e-109	387.00
IUUC-Gmo-039565	Gadus morhua	97.99	2.00e-117	414.00
IUUC-Gga-040182	Gallus gallus	92.50	4.00e-109	387.00
IUUC-Gac-041909	Gasterosteus aculeatus	98.49	4.00e-118	416.00
IUUC-Ggo-045150	Gorilla gorilla	92.00	1.00e-110	392.00
IUUC-Hsa-046611	Homo sapiens	92.50	1.00e-111	395.00
IUUC-Itr-047984	Ictidomys tridecemlineatus	85.00	6.00e-98	349.00
IUUC-Lch-050173	Latimeria chalumnae	92.00	1.00e-111	395.00
IUUC-Loc-051916	Lepisosteus oculatus	93.03	3.00e-111	394.00
IUUC-Laf-053860	Loxodonta africana	92.50	1.00e-111	395.00
IUUC-Mcc-054820	Macaca mulatta	92.50	1.00e-111	395.00
IUUC-Meu-056681	Macropus eugenii	87.00	1.00e-104	372.00
IUUC-Mmr-060666	Microcebus murinus	92.50	1.00e-111	395.00
IUUC-Mdo-062804	Monodelphis domestica	92.50	4.00e-112	397.00
IUUC-Mmu-063472	Mus musculus	92.50	1.00e-111	395.00
IUUC-Mlu-067397	Myotis lucifugus	89.34	3.00e-105	374.00
IUUC-Nle-070152	Nomascus leucogenys	98.17	3.00e-63	232.00
IUUC-Ocu-074229	Oryctolagus cuniculus	94.15	6.00e-107	380.00
IUUC-Ola-086587	Oryzias latipes	95.38	6.00e-129	453.00
IUUC-Oga-089161	Otolemur garnettii	94.12	2.00e-106	378.00
IUUC-Oar-089383	Ovis aries	92.50	1.00e-111	395.00
IUUC-Ptr-091096	Pan troglodytes	92.50	1.00e-111	395.00
IUUC-Pan-092560	Papio anubis	94.12	2.00e-106	378.00
IUUC-Psi-093263	Pelodiscus sinensis	93.71	2.00e-80	291.00
IUUC-Pfo-096974	Poecilia formosa	96.15	4.00e-130	457.00
IUUC-Pab-098344	Pongo abelii	92.50	1.00e-111	395.00
IUUC-Rno-105821	Rattus norvegicus	92.50	1.00e-111	395.00
IUUC-Sha-107364	Sarcophilus harrisii	92.50	4.00e-112	397.00
IUUC-Sar-112992	Sorex araneus	89.55	3.00e-103	367.00
IUUC-Tgu-117074	Taeniopygia guttata	92.50	4.00e-109	387.00
IUUC-Tru-118641	Takifugu rubripes	93.08	3.00e-126	444.00
IUUC-Tsy-118797	Tarsius syrichta	92.03	9.00e-75	272.00
IUUC-Tni-119817	Tetraodon nigroviridis	84.62	1.00e-119	422.00
IUUC-Tbe-128014	Tupaia belangeri	92.50	1.00e-111	395.00
IUUC-Ttr-129037	Tursiops truncatus	94.51	4.00e-102	363.00
IUUC-Vpa-130680	Vicugna pacos	94.33	4.00e-79	286.00
IUUC-Xtr-131819	Xenopus tropicalis	94.59	2.00e-105	375.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence