iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006740

Ensembl Protein ID

AT3G18060.1

UniProt Accession

Q9LV35; AIP12_ARATH

Genbank Protein ID

BAB02018.1; AEE76041.1; AAL32514.1; AAM47943.1

Protein Name

Actin-interacting protein 1-2

Genbank Nucleotide ID

AB020749; CP002686; AY062436; AY114624

Gene Name

AIP1-2; At3g18060; MRC8.4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G18060	AT3G18060.1	AT3G18060.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.00e-32	109.8	230	263
UBD/Beta-Prp	3.60e-62	211.1	50	312

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           gH++s++++++ +d + +++ s D++ k+WD+++
   Q: 230  GHKGSIYAVSWsPDgKQVLTVSADKSAKIWDISD 263
           8***********999****************765 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD....rtikvwdlstgkcvhtlkgheds 96
           ++ g+h  + t+  +sp+++++a+g  +gt+++w + +  +l+   +   + + ++++s dg +++ +s D     +++ +  ++g+ v  + gh+++
   Q: 50   SIYGEHAYPATVARYSPNGEWIASGDVSGTVRIWGAYNDHVLKNEfKVLAGRIDDLQWSADG-MRIVASGDgkgkSLVRAFMWDSGSNVGEFDGHSRR 146
           5668899999*9**********************988777765544999999*********9.7888888879999********************** PP
   S: 97   vlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgghtdsvyslsfdsn 191
           vls+++ p++  ++v+ ++d  ++ ++ +  +      ++h+ +vncv++ pdg+ +++ s D++  ++d kt ++l +l    gh++s+y +s++++
   Q: 147  VLSCAIKPTRpFRIVTCGEDFLVNFYEGPPFKFKL-SSREHSNFVNCVRFAPDGSKFITVSSDKKGIIYDGKTCEILGELssDDGHKGSIYAVSWSPD 243
           ********99899*******************999.9*******************************************88455************* PP
   S: 192  gkelvsgsldgtvklwdlq...tgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW...d 250
           gk+++++s d++ k+wd++   +g+   tln+       d +++  ++ +++++v++s  g+i+i+   d
   Q: 244  GKQVLTVSADKSAKIWDISdngSGSLNTTLNCPGssggvDDMLVGCLW-QNDHIVTVSLGGTISIFsasD 312
           ********************9988888888876645444555555556.88889999*9****9984444 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Binds actin. Enhances the F-actin depolymerization activity of actin-depolymerizing factor (ADF) proteins.

Protein Sequence
(Fasta)

MELSETYACV PSTERGRGIL ISGNSKSDTI LYTNGRSVVT LDLNNPLKVS IYGEHAYPAT 60
VARYSPNGEW IASGDVSGTV RIWGAYNDHV LKNEFKVLAG RIDDLQWSAD GMRIVASGDG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAAGTCTTA AGAAACAAAG TGATTAGCAC AAAACTATTA TACAACTACA CTTTACATTA 60
TTTTTGGGTT ATCTAATGAG TTTGTGCCAG AGAAGTGAAT GTTGCAACAA TGATTATCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0009--Actin-binding
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011045--N2O_reductase_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0042643--C:actomyosin, actin portion
GO:0030864--C:cortical actin cytoskeleton
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0051015--F:actin filament binding
GO:0030042--P:actin filament depolymerization
GO:0030836--P:positive regulation of actin filament depolymerization

KEGG

ath:AT3G18060

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	67.33	0.00e+00	720.00
IUUC-Aml-002368	Ailuropoda melanoleuca	36.76	9.00e-108	383.00
IUUC-Atr-003160	Amborella trichopoda	72.79	0.00e+00	931.00
IUUC-Apl-004012	Anas platyrhynchos	39.12	5.00e-110	390.00
IUUC-Aca-004707	Anolis carolinensis	37.85	1.00e-112	399.00
IUUC-Aly-006465	Arabidopsis lyrata	97.04	0.00e+00	1192.00
IUUC-Acl-008262	Aspergillus clavatus	33.22	2.00e-84	306.00
IUUC-Afu-008989	Aspergillus fumigatus	32.14	2.00e-75	275.00
IUUC-Ani-009167	Aspergillus nidulans	32.24	3.00e-89	322.00
IUUC-Ang-009595	Aspergillus niger	31.86	4.00e-79	288.00
IUUC-Aor-009908	Aspergillus oryzae	32.14	1.00e-84	306.00
IUUC-Ate-010580	Aspergillus terreus	32.46	2.00e-83	304.00
IUUC-Ame-011269	Astyanax mexicanus	43.16	2.00e-44	172.00
IUUC-Bgr-011996	Blumeria graminis	30.57	7.00e-82	297.00
IUUC-Bta-013278	Bos taurus	36.81	1.00e-112	400.00
IUUC-Bdi-014659	Brachypodium distachyon	64.37	0.00e+00	825.00
IUUC-Bol-016529	Brassica oleracea	91.02	0.00e+00	955.00
IUUC-Bra-017139	Brassica rapa	90.97	0.00e+00	1133.00
IUUC-Cja-019952	Callithrix jacchus	36.91	3.00e-105	375.00
IUUC-Cfa-020225	Canis familiaris	36.59	2.00e-110	392.00
IUUC-Cpo-021900	Cavia porcellus	36.93	4.00e-106	378.00
IUUC-Csa-023028	Chlorocebus sabaeus	37.07	1.00e-105	376.00
IUUC-Cho-025030	Choloepus hoffmanni	30.84	3.00e-67	248.00
IUUC-Cin-025152	Ciona intestinalis	39.68	1.00e-53	202.00
IUUC-Csv-025986	Ciona savignyi	31.49	6.00e-61	227.00
IUUC-Cne-026814	Cryptococcus neoformans	30.89	7.00e-73	267.00
IUUC-Dre-027498	Danio rerio	43.01	2.00e-44	171.00
IUUC-Dno-029383	Dasypus novemcinctus	37.40	3.00e-105	375.00
IUUC-Dor-030633	Dipodomys ordii	35.84	6.00e-97	347.00
IUUC-Dme-031597	Drosophila melanogaster	36.89	1.00e-115	409.00
IUUC-Ete-032780	Echinops telfairi	33.50	6.00e-91	327.00
IUUC-Eca-034306	Equus caballus	35.78	7.00e-104	370.00
IUUC-Eeu-034531	Erinaceus europaeus	32.82	3.00e-36	145.00
IUUC-Fca-036301	Felis catus	37.75	3.00e-112	398.00
IUUC-Fal-037361	Ficedula albicollis	38.57	2.00e-117	416.00
IUUC-Gmo-039238	Gadus morhua	36.01	1.00e-101	363.00
IUUC-Gga-040235	Gallus gallus	38.86	2.00e-109	389.00
IUUC-Gac-042363	Gasterosteus aculeatus	37.40	3.00e-111	395.00
IUUC-Gma-043218	Glycine max	75.78	0.00e+00	977.00
IUUC-Ggo-044632	Gorilla gorilla	35.55	6.00e-100	357.00
IUUC-Hsa-045792	Homo sapiens	37.40	7.00e-111	393.00
IUUC-Hvu-047517	Hordeum vulgare	66.17	0.00e+00	866.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	37.42	1.00e-108	386.00
IUUC-Lch-050428	Latimeria chalumnae	38.60	2.00e-116	412.00
IUUC-Lpe-051306	Leersia perrieri	68.97	0.00e+00	892.00
IUUC-Loc-052096	Lepisosteus oculatus	34.39	4.00e-91	328.00
IUUC-Lma-053313	Leptosphaeria maculans	35.29	2.00e-91	331.00
IUUC-Laf-054060	Loxodonta africana	36.33	1.00e-107	383.00
IUUC-Mcc-055619	Macaca mulatta	36.30	3.00e-101	362.00
IUUC-Meu-056689	Macropus eugenii	35.46	6.00e-65	241.00
IUUC-Mtr-057922	Medicago truncatula	75.16	0.00e+00	960.00
IUUC-Mla-059103	Melampsora laricipopulina	30.86	2.00e-71	262.00
IUUC-Mga-060150	Meleagris gallopavo	39.09	1.00e-109	389.00
IUUC-Mvi-060448	Microbotryum violaceum	28.69	3.00e-59	222.00
IUUC-Mmr-061226	Microcebus murinus	36.33	4.00e-104	371.00
IUUC-Mdo-062674	Monodelphis domestica	37.24	1.00e-111	396.00
IUUC-Mmu-064170	Mus musculus	36.26	1.00e-107	383.00
IUUC-Mac-065124	Musa acuminata	72.37	0.00e+00	942.00
IUUC-Mpu-066001	Mustela putorius furo	35.58	2.00e-105	376.00
IUUC-Mlu-067253	Myotis lucifugus	37.42	2.00e-106	379.00
IUUC-Nfi-068550	Neosartorya fischeri	32.08	3.00e-85	308.00
IUUC-Nle-070115	Nomascus leucogenys	35.65	8.00e-95	340.00
IUUC-Opr-070254	Ochotona princeps	36.93	2.00e-100	358.00
IUUC-Ont-071666	Oreochromis niloticus	39.19	2.00e-108	385.00
IUUC-Oan-073292	Ornithorhynchus anatinus	46.76	3.00e-35	140.00
IUUC-Ocu-074824	Oryctolagus cuniculus	35.50	5.00e-100	357.00
IUUC-Oba-075010	Oryza barthii	67.65	0.00e+00	884.00
IUUC-Obr-076364	Oryza brachyantha	68.14	0.00e+00	877.00
IUUC-Ogl-077019	Oryza glaberrima	67.65	0.00e+00	884.00
IUUC-Ogu-078496	Oryza glumaepatula	67.65	0.00e+00	884.00
IUUC-Oin-080116	Oryza indica	67.49	0.00e+00	882.00
IUUC-Olo-080290	Oryza longistaminata	67.82	0.00e+00	887.00
IUUC-Ome-081969	Oryza meridionalis	67.49	0.00e+00	882.00
IUUC-Oni-082075	Oryza nivara	67.65	0.00e+00	884.00
IUUC-Opu-083959	Oryza punctata	67.82	0.00e+00	880.00
IUUC-Oru-084711	Oryza rufipogon	67.65	0.00e+00	884.00
IUUC-Osa-085958	Oryza sativa	67.49	0.00e+00	882.00
IUUC-Ola-086968	Oryzias latipes	37.13	1.00e-111	396.00
IUUC-Oga-089108	Otolemur garnettii	36.29	1.00e-109	389.00
IUUC-Oar-089986	Ovis aries	34.25	2.00e-98	352.00
IUUC-Ptr-091281	Pan troglodytes	37.42	6.00e-110	390.00
IUUC-Pan-092585	Papio anubis	37.07	7.00e-106	377.00
IUUC-Psi-093811	Pelodiscus sinensis	37.34	5.00e-111	394.00
IUUC-Pma-094396	Petromyzon marinus	35.31	3.00e-108	385.00
IUUC-Pno-095086	Phaeosphaeria nodorum	32.70	7.00e-86	310.00
IUUC-Ppa-095876	Physcomitrella patens	56.44	0.00e+00	718.00
IUUC-Pfo-096973	Poecilia formosa	38.70	1.00e-120	426.00
IUUC-Pab-098391	Pongo abelii	37.07	1.00e-105	376.00
IUUC-Pop-098850	Populus trichocarpa	80.43	0.00e+00	1018.00
IUUC-Pca-100257	Procavia capensis	56.25	5.00e-24	105.00
IUUC-Ppe-101578	Prunus persica	77.14	0.00e+00	985.00
IUUC-Pva-102872	Pteropus vampyrus	34.74	2.00e-103	369.00
IUUC-Pgr-103593	Puccinia graminis	30.23	8.00e-69	254.00
IUUC-Pte-104365	Pyrenophora teres	33.01	5.00e-83	301.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	32.68	3.00e-85	308.00
IUUC-Rno-105737	Rattus norvegicus	36.26	1.00e-111	396.00
IUUC-Sha-107084	Sarcophilus harrisii	35.95	5.00e-90	324.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	32.73	3.00e-89	322.00
IUUC-Spo-108309	Schizosaccharomyces pombe	33.50	3.00e-84	305.00
IUUC-Smo-109255	Selaginella moellendorffii	53.92	0.00e+00	652.00
IUUC-Sit-109962	Setaria italica	67.82	0.00e+00	884.00
IUUC-Sly-110897	Solanum lycopersicum	76.15	0.00e+00	971.00
IUUC-Stu-111971	Solanum tuberosum	76.64	0.00e+00	978.00
IUUC-Sbi-114857	Sorghum bicolor	68.64	0.00e+00	885.00
IUUC-Tgu-117256	Taeniopygia guttata	38.93	3.00e-118	418.00
IUUC-Tru-117871	Takifugu rubripes	36.97	3.00e-110	392.00
IUUC-Tsy-119172	Tarsius syrichta	43.15	7.00e-57	214.00
IUUC-Tni-120339	Tetraodon nigroviridis	36.99	4.00e-112	397.00
IUUC-Tca-121609	Theobroma cacao	77.39	0.00e+00	990.00
IUUC-Tvi-122528	Trichoderma virens	32.95	3.00e-88	318.00
IUUC-Tae-123530	Triticum aestivum	66.17	0.00e+00	865.00
IUUC-Tur-126845	Triticum urartu	61.14	0.00e+00	692.00
IUUC-Tme-127217	Tuber melanosporum	31.83	8.00e-81	294.00
IUUC-Tbe-127526	Tupaia belangeri	34.50	6.00e-105	374.00
IUUC-Ttr-128898	Tursiops truncatus	33.01	8.00e-92	330.00
IUUC-Vvi-131217	Vitis vinifera	78.12	0.00e+00	981.00
IUUC-Xtr-132860	Xenopus tropicalis	34.51	1.00e-92	333.00
IUUC-Xma-133830	Xiphophorus maculatus	38.70	5.00e-121	427.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence