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Tag Content
iUUCD ID IUUC-Mlu-066980
Ensembl Protein ID ENSMLUP00000010693.2
UniProt Accession G1PIY7; G1PIY7_MYOLU
Genbank Protein ID ENSMLUP00000010693
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAPE02015885
Gene Name PML
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMLUG00000011733.2 ENSMLUT00000011739.2 ENSMLUP00000010693.2
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 78.65 0.00e+00 1201.00 IUUC-Hsa-045861
E3 activity/RING/RING 64.72 0.00e+00 953.00 IUUC-Mmu-063118
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Myotis lucifugus
Protein Sequence
(Fasta)
MQPEPAPARS SGTQQDSALP DMSTMPPPES PSESQQPSPD HSPTEQTTEE EFQFLRCHGC 60
QAEAKCPKLL LCLHTLCSGC LQAPDMQCPI CQASLPPGAD GPVLDNIFFE SLQRRLSVYQ 120
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Protein Fasta Sequence



>IUUC-Mlu-066980|E3,RING|Myotis lucifugus
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Nucleotide Sequence
(Fasta)
ATGCAGCCGG AGCCTGCACC CGCCAGATCT TCGGGGACCC AACAGGACTC CGCACTGCCC 60
GACATGTCCA CCATGCCTCC CCCGGAGTCT CCCTCCGAAA GCCAGCAGCC CAGCCCGGAC 120
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Nucleotide Fasta Sequence



>IUUC-Mlu-066980|E3,RING|Myotis lucifugus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR021978--DUF3583
IPR012337--RNaseH-like_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12126--DUF3583
PF00643--zf-B_box

SMART

SM00336--BBOX

Gene Ontology

GO:0005829--C:cytosol
GO:0042406--C:extrinsic component of endoplasmic reticulum membrane
GO:0000784--C:nuclear chromosome, telomeric region
GO:0016363--C:nuclear matrix
GO:0031965--C:nuclear membrane
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0007050--P:cell cycle arrest
GO:0045165--P:cell fate commitment
GO:0071353--P:cellular response to interleukin-4
GO:0090398--P:cellular senescence
GO:0032922--P:circadian regulation of gene expression
GO:0007182--P:common-partner SMAD protein phosphorylation
GO:0006977--P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0032469--P:endoplasmic reticulum calcium ion homeostasis
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0097191--P:extrinsic apoptotic signaling pathway
GO:0010761--P:fibroblast migration
GO:0045087--P:innate immune response
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0051457--P:maintenance of protein location in nucleus
GO:0030099--P:myeloid cell differentiation
GO:0016525--P:negative regulation of angiogenesis
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0050713--P:negative regulation of interleukin-1 beta secretion
GO:2000059--P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1902187--P:negative regulation of viral release from host cell
GO:0030578--P:PML body organization
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0048146--P:positive regulation of fibroblast proliferation
GO:0045345--P:positive regulation of MHC class I biosynthetic process
GO:0032206--P:positive regulation of telomere maintenance
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006461--P:protein complex assembly
GO:0010522--P:regulation of calcium ion transport into cytosol
GO:0030155--P:regulation of cell adhesion
GO:2000779--P:regulation of double-strand break repair
GO:0001932--P:regulation of protein phosphorylation
GO:0010332--P:response to gamma radiation
GO:0001666--P:response to hypoxia
GO:0009411--P:response to UV
GO:0048384--P:retinoic acid receptor signaling pathway
GO:0007184--P:SMAD protein import into nucleus
GO:0007179--P:transforming growth factor beta receptor signaling pathway

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001901 Ailuropoda melanoleuca 74.57 0.00e+00 1137.00
IUUC-Bta-012427 Bos taurus 71.30 0.00e+00 1157.00
IUUC-Cja-019029 Callithrix jacchus 77.26 0.00e+00 1196.00
IUUC-Cfa-021127 Canis familiaris 73.52 0.00e+00 1141.00
IUUC-Cpo-022553 Cavia porcellus 65.90 0.00e+00 967.00
IUUC-Csa-023187 Chlorocebus sabaeus 75.09 0.00e+00 802.00
IUUC-Cho-024937 Choloepus hoffmanni 67.55 6.00e-96 345.00
IUUC-Dno-029326 Dasypus novemcinctus 73.68 0.00e+00 1108.00
IUUC-Dor-030808 Dipodomys ordii 60.48 0.00e+00 674.00
IUUC-Ete-032746 Echinops telfairi 54.31 2.00e-172 599.00
IUUC-Eca-033234 Equus caballus 77.80 0.00e+00 1160.00
IUUC-Fca-035648 Felis catus 77.98 0.00e+00 1224.00
IUUC-Ggo-044927 Gorilla gorilla 77.89 0.00e+00 1240.00
IUUC-Hsa-045861 Homo sapiens 77.89 0.00e+00 1239.00
IUUC-Itr-047861 Ictidomys tridecemlineatus 76.93 0.00e+00 1226.00
IUUC-Loc-052276 Lepisosteus oculatus 35.15 2.00e-50 194.00
IUUC-Laf-054059 Loxodonta africana 71.56 0.00e+00 1089.00
IUUC-Meu-056495 Macropus eugenii 54.14 2.00e-102 367.00
IUUC-Mga-059224 Meleagris gallopavo 42.02 2.00e-41 164.00
IUUC-Mmr-061507 Microcebus murinus 73.68 0.00e+00 1134.00
IUUC-Mdo-062196 Monodelphis domestica 46.58 0.00e+00 640.00
IUUC-Mmu-063118 Mus musculus 64.16 0.00e+00 1016.00
IUUC-Mpu-066024 Mustela putorius furo 70.68 0.00e+00 1097.00
IUUC-Nle-069779 Nomascus leucogenys 76.98 0.00e+00 1165.00
IUUC-Ocu-074016 Oryctolagus cuniculus 64.33 0.00e+00 974.00
IUUC-Oga-089085 Otolemur garnettii 67.68 0.00e+00 1050.00
IUUC-Oar-089980 Ovis aries 68.68 0.00e+00 1093.00
IUUC-Ptr-091681 Pan troglodytes 77.83 0.00e+00 1237.00
IUUC-Pan-091965 Papio anubis 77.21 0.00e+00 1172.00
IUUC-Psi-093577 Pelodiscus sinensis 38.08 2.00e-107 383.00
IUUC-Pab-098215 Pongo abelii 73.72 4.00e-179 622.00
IUUC-Pca-100883 Procavia capensis 69.72 0.00e+00 805.00
IUUC-Pva-102465 Pteropus vampyrus 74.96 0.00e+00 833.00
IUUC-Rno-105120 Rattus norvegicus 64.19 0.00e+00 1046.00
IUUC-Sar-113320 Sorex araneus 62.21 1.00e-87 317.00
IUUC-Ssc-116042 Sus scrofa 74.21 0.00e+00 1170.00
IUUC-Tbe-127880 Tupaia belangeri 60.39 0.00e+00 816.00
Created Date 25-Jun-2017

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