iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037088

Ensembl Protein ID

ENSFALP00000011157.1

UniProt Accession

U3K803; U3K803_FICAL

Genbank Protein ID

ENSFALP00000011157

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01012002

Gene Name

USP47

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000010692.1	ENSFALT00000011202.1	ENSFALP00000011157.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.60e-76	256.7	51	425

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl N+  tCY+NS+LQ+L+++pe+r++l +    +++e++ ++p+ ++  +lq+lf  l++skk+a++++++++++++ ++e    +q
   Q: 51   VGLVNQAMTCYLNSLLQTLFMTPEFRNALYK---WEFEESE-EDPERSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSE--AWQQ 133
           6******************************...5555443.6899*********************************9998..9*** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++++d+le++                           k++++ +li++l+qg+lk+ ++clec+ +  r ++ ld++l ++ 
   Q: 134  HDVQELCRVMFDALEQKW--------------------------KQTEQADLINQLYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRP 196
           ******************..........................678999*************************************95 PP
   S: 179  ke.etkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfct 266
              +++  s++++L++f ++e l+g n+y+ce+ckkk++a+k l++ ++P  L+l+LkRf f+ ++++r+k+n++++fp+eLd+s f  
   Q: 197  YGsSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSVFID 285
           54045678*****************************************************************************9999 PP
   S: 267  speekqke.....................................................kkkYeLiavvvHsGslssGHYvayvkn. 301
            ++ek+ +                                                     +  YeL++v+vHsGs+ +GHY+a++k+ 
   Q: 286  VEDEKSPQtesctdsgaenegschsdqmsndfsnddgvdegiclesnsaaeriskagseksSLLYELFSVMVHSGSAAGGHYYACIKSf 374
           8666665577777888888888888888888888888888888888888888888888888***************************5 PP
   S: 302  ekgkWllfdDskVtevkeeevleetg................staYvlfYk 336
           ++++W+ f+D++V+++++e+++++ g                ++aY+l+Y+
   Q: 375  SDDQWYSFNDQHVSKITQEDIKKTYGgssgsrgyyssafassTNAYMLIYR 425
           5666*******************888************************8 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MQEEAGTAED GAQERFIGPL PREGSMGCTN DYVSQSYSYS SVLSKSETGY VGLVNQAMTC 60
YLNSLLQTLF MTPEFRNALY KWEFEESEED PERSIPYQLQ RLFVLLQTSK KRAIETTDVT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATATGGATC TGTTTCTAGA AAGTGTTGTT TATGTTGTTT TAATCTTTTT TAGCAGACTC 60
CAATAGATCA GAACAGTGAC AAAACCATTC TTGATGCTGG TTTTGAGCCA GGGAAAAAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF14560--Ubiquitin_2
PF00443--UCH

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006284--P:base-excision repair
GO:0034644--P:cellular response to UV
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0010972--P:negative regulation of G2/M transition of mitotic cell cycle
GO:1902230--P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0030307--P:positive regulation of cell growth
GO:0042493--P:response to drug
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002228	Ailuropoda melanoleuca	88.33	0.00e+00	2075.00
IUUC-Apl-003486	Anas platyrhynchos	95.23	0.00e+00	2223.00
IUUC-Aca-005061	Anolis carolinensis	91.11	0.00e+00	2177.00
IUUC-Ame-011206	Astyanax mexicanus	81.73	0.00e+00	1892.00
IUUC-Bta-012942	Bos taurus	88.78	0.00e+00	2120.00
IUUC-Cel-018600	Caenorhabditis elegans	37.66	6.00e-121	429.00
IUUC-Cja-018950	Callithrix jacchus	90.15	0.00e+00	2120.00
IUUC-Cfa-020299	Canis familiaris	90.07	0.00e+00	2131.00
IUUC-Cpo-021943	Cavia porcellus	89.75	0.00e+00	2113.00
IUUC-Csa-023285	Chlorocebus sabaeus	90.31	0.00e+00	2125.00
IUUC-Cho-025006	Choloepus hoffmanni	84.92	0.00e+00	1913.00
IUUC-Cin-025145	Ciona intestinalis	41.32	0.00e+00	697.00
IUUC-Csv-025839	Ciona savignyi	49.32	6.00e-161	561.00
IUUC-Dre-027959	Danio rerio	82.36	0.00e+00	1839.00
IUUC-Dno-030023	Dasypus novemcinctus	87.37	0.00e+00	2009.00
IUUC-Dor-030994	Dipodomys ordii	86.91	0.00e+00	863.00
IUUC-Dme-031604	Drosophila melanogaster	49.22	2.00e-144	507.00
IUUC-Ete-032596	Echinops telfairi	74.24	0.00e+00	744.00
IUUC-Eca-033913	Equus caballus	89.03	0.00e+00	2128.00
IUUC-Eeu-034518	Erinaceus europaeus	82.57	0.00e+00	1890.00
IUUC-Fca-035997	Felis catus	89.68	0.00e+00	2122.00
IUUC-Gmo-038920	Gadus morhua	78.84	0.00e+00	1805.00
IUUC-Gga-040953	Gallus gallus	96.29	0.00e+00	2224.00
IUUC-Gac-042400	Gasterosteus aculeatus	79.92	0.00e+00	1811.00
IUUC-Ggo-044820	Gorilla gorilla	91.27	0.00e+00	2093.00
IUUC-Hsa-046634	Homo sapiens	90.23	0.00e+00	2117.00
IUUC-Lch-050440	Latimeria chalumnae	86.60	0.00e+00	2056.00
IUUC-Loc-051904	Lepisosteus oculatus	84.96	0.00e+00	2000.00
IUUC-Laf-053760	Loxodonta africana	89.60	0.00e+00	2120.00
IUUC-Mcc-054637	Macaca mulatta	90.31	0.00e+00	2122.00
IUUC-Meu-056904	Macropus eugenii	89.31	0.00e+00	1574.00
IUUC-Mga-059556	Meleagris gallopavo	95.24	0.00e+00	2198.00
IUUC-Mmr-061192	Microcebus murinus	90.31	0.00e+00	2120.00
IUUC-Mdo-061929	Monodelphis domestica	90.31	0.00e+00	2140.00
IUUC-Mmu-063726	Mus musculus	88.62	0.00e+00	2115.00
IUUC-Mpu-066014	Mustela putorius furo	90.23	0.00e+00	2135.00
IUUC-Mlu-067232	Myotis lucifugus	89.69	0.00e+00	2108.00
IUUC-Nle-069619	Nomascus leucogenys	90.15	0.00e+00	2120.00
IUUC-Opr-070224	Ochotona princeps	84.73	0.00e+00	1044.00
IUUC-Ont-071384	Oreochromis niloticus	81.78	0.00e+00	1856.00
IUUC-Oan-073208	Ornithorhynchus anatinus	86.27	0.00e+00	2045.00
IUUC-Ocu-074285	Oryctolagus cuniculus	89.83	0.00e+00	2112.00
IUUC-Ola-087051	Oryzias latipes	81.78	0.00e+00	1812.00
IUUC-Oga-088928	Otolemur garnettii	89.99	0.00e+00	2116.00
IUUC-Oar-090215	Ovis aries	88.81	0.00e+00	2122.00
IUUC-Ptr-091035	Pan troglodytes	90.23	0.00e+00	2120.00
IUUC-Pan-092377	Papio anubis	89.75	0.00e+00	2100.00
IUUC-Pfo-096722	Poecilia formosa	80.93	0.00e+00	1840.00
IUUC-Pab-098723	Pongo abelii	90.23	0.00e+00	2122.00
IUUC-Pca-100105	Procavia capensis	84.67	0.00e+00	1913.00
IUUC-Pva-102514	Pteropus vampyrus	91.85	0.00e+00	645.00
IUUC-Rno-105384	Rattus norvegicus	89.06	0.00e+00	2077.00
IUUC-Sha-106982	Sarcophilus harrisii	88.14	0.00e+00	2122.00
IUUC-Sar-113723	Sorex araneus	82.35	0.00e+00	879.00
IUUC-Ssc-115671	Sus scrofa	89.49	0.00e+00	1897.00
IUUC-Tgu-116722	Taeniopygia guttata	97.18	0.00e+00	2265.00
IUUC-Tru-118380	Takifugu rubripes	80.34	0.00e+00	1860.00
IUUC-Tsy-119646	Tarsius syrichta	83.13	0.00e+00	1929.00
IUUC-Tni-120762	Tetraodon nigroviridis	80.10	0.00e+00	1864.00
IUUC-Tbe-127861	Tupaia belangeri	87.73	0.00e+00	2008.00
IUUC-Ttr-129254	Tursiops truncatus	81.30	0.00e+00	1223.00
IUUC-Vpa-130141	Vicugna pacos	83.66	0.00e+00	1036.00
IUUC-Xtr-132700	Xenopus tropicalis	82.64	0.00e+00	1966.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence