iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000008574.3	ENSMMUT00000075160.1	ENSMMUP00000054736.1
ENSMMUG00000008574.3	ENSMMUT00000053564.1	ENSMMUP00000042415.1
ENSMMUG00000008574.3	ENSMMUT00000011988.3	ENSMMUP00000011245.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-82	278.8	44	353

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           tGl+NlgNtCYmN++LQcL +i++l e++l+ k+  +l     +++  e++++++ l++ +w +++  vsp+ + +al+++ + f++  
   Q: 44   TGLRNLGNTCYMNAILQCLCSISPLVEYFLSgKYITAL-----QNDCSEVATAFAYLMTDMWLGDSDCVSPEIFRSALGNLYPAFTKKT 127
           7******************************3333333.....35678***************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvp 177
           qqDaqEfl ++l++l+e+lkk    ++ + + ++++ + +   +k  + ++s+i++lF+gql  +i+cl+c++ + ++e f+ lslp+p
   Q: 128  QQDAQEFLIYVLNELHEALKK---YHYPRRR-SHEKGSAQRCCRKWITTETSVITQLFEGQLNYSIVCLKCEKCTYKNEVFTVLSLPIP 212
           *******************54...2222222.233445566678999999*************************************** PP
   S: 178  gkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfc 265
           ++ e+   slqdcL+ f+++++l+ +n+++c+ c+ kqe+  + +++k P+++i+hLkRf  + ++  ++k+ + +++pl+ Ldl+p+ 
   Q: 213  SEYEC---SLQDCLQCFFQQDTLTWNNQIHCSFCETKQETAVRAGISKAPKIIIFHLKRF--DIQGTTKRKLRTDIHYPLTnLDLTPYI 296
           *****...****************************************************..66778999******************* PP
   S: 266  tspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevle 324
           +   +k   + kY+L+avv+H G l++GHY+a++kn+  + W  fdD++V+e++ ++ ++
   Q: 297  CPIFRK---YPKYNLCAVVNHFGDLDGGHYTAFCKNSFTQaWNSFDDTRVSEIPDTSGVK 353
           **6655...8**************************76668************9876655 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MTSQRSLPAD DFGIYYVLAE CTDYYDTLPV KEADGSQPCS QGVTGLRNLG NTCYMNAILQ 60
CLCSISPLVE YFLSGKYITA LQNDCSEVAT AFAYLMTDMW LGDSDCVSPE IFRSALGNLY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTTCTC AGCGATCTCT CCCTGCAGAT GACTTCGGTA TCTACTATGT CCTGTGAGCC 60
TTGATCTACT ACAGCTTTCT AGATAAGCCC AGCTCAGAGG AGTCAGGGGA TACATGCTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002089	Ailuropoda melanoleuca	88.00	0.00e+00	640.00
IUUC-Aca-005256	Anolis carolinensis	48.09	3.00e-90	325.00
IUUC-Bta-012753	Bos taurus	82.00	9.00e-171	592.00
IUUC-Cfa-020054	Canis familiaris	87.13	3.00e-177	613.00
IUUC-Cpo-021375	Cavia porcellus	79.27	9.00e-160	556.00
IUUC-Csa-023902	Chlorocebus sabaeus	98.64	3.00e-129	453.00
IUUC-Cho-024755	Choloepus hoffmanni	75.88	3.00e-146	511.00
IUUC-Dor-030311	Dipodomys ordii	87.91	7.00e-95	340.00
IUUC-Ete-032570	Echinops telfairi	65.31	1.00e-106	379.00
IUUC-Eca-034343	Equus caballus	87.43	0.00e+00	633.00
IUUC-Eeu-034510	Erinaceus europaeus	85.05	3.00e-164	570.00
IUUC-Fca-035920	Felis catus	86.29	0.00e+00	636.00
IUUC-Fal-036903	Ficedula albicollis	55.76	4.00e-102	364.00
IUUC-Gac-042261	Gasterosteus aculeatus	43.22	6.00e-68	251.00
IUUC-Ggo-045650	Gorilla gorilla	86.45	1.00e-71	262.00
IUUC-Hsa-046665	Homo sapiens	89.21	0.00e+00	627.00
IUUC-Itr-048167	Ictidomys tridecemlineatus	91.43	0.00e+00	676.00
IUUC-Lch-049925	Latimeria chalumnae	56.21	2.00e-96	345.00
IUUC-Loc-051880	Lepisosteus oculatus	47.99	2.00e-75	277.00
IUUC-Laf-054494	Loxodonta africana	88.29	0.00e+00	651.00
IUUC-Meu-055906	Macropus eugenii	76.88	3.00e-156	544.00
IUUC-Mmr-061564	Microcebus murinus	65.29	2.00e-113	401.00
IUUC-Mdo-061800	Monodelphis domestica	74.73	7.00e-163	566.00
IUUC-Mmu-063618	Mus musculus	82.00	3.00e-171	594.00
IUUC-Mpu-066699	Mustela putorius furo	88.57	0.00e+00	648.00
IUUC-Mlu-067672	Myotis lucifugus	85.43	9.00e-180	622.00
IUUC-Opr-070949	Ochotona princeps	85.49	3.00e-159	554.00
IUUC-Ont-072200	Oreochromis niloticus	44.69	7.00e-64	238.00
IUUC-Oan-073725	Ornithorhynchus anatinus	65.32	1.00e-132	465.00
IUUC-Ocu-074021	Oryctolagus cuniculus	91.43	0.00e+00	670.00
IUUC-Oga-088258	Otolemur garnettii	88.92	2.00e-169	588.00
IUUC-Oar-089881	Ovis aries	84.86	3.00e-179	620.00
IUUC-Ptr-090988	Pan troglodytes	90.45	3.00e-177	613.00
IUUC-Pan-091773	Papio anubis	98.86	0.00e+00	726.00
IUUC-Psi-093243	Pelodiscus sinensis	74.32	2.00e-130	457.00
IUUC-Pab-097713	Pongo abelii	91.22	0.00e+00	667.00
IUUC-Pca-100226	Procavia capensis	67.65	2.00e-132	464.00
IUUC-Pva-103172	Pteropus vampyrus	87.94	2.00e-179	621.00
IUUC-Rno-105950	Rattus norvegicus	84.00	9.00e-175	605.00
IUUC-Sha-107026	Sarcophilus harrisii	74.58	4.00e-159	553.00
IUUC-Ssc-116383	Sus scrofa	88.00	0.00e+00	646.00
IUUC-Tgu-116511	Taeniopygia guttata	55.42	1.00e-95	342.00
IUUC-Tsy-119444	Tarsius syrichta	93.91	8.00e-64	237.00
IUUC-Tbe-127808	Tupaia belangeri	83.94	5.00e-62	231.00
IUUC-Ttr-129046	Tursiops truncatus	83.53	2.00e-167	581.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence