iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132461

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01083421

Gene Name

rnf139

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000017487.3	ENSXETT00000037995.3	ENSXETP00000037995.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.10e-07	32.5	549	587

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           CaiC+++f +  +++pC H fha Cl kw       + +++CP C
   Q: 549  CAICYQEFHTSARITPCHHYFHALCLRKW------LYIQDTCPMC 587
           ********999******************......********** PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

EGAAEPMESP PVVVGQRVRA VLDVALRVPS LFITDAILNL PHDASAGFLS LLLQLALRLL 60
GVVASIVVLV LSRRALFKFY MITAALALAA TSVLVSYYAT LHLNFSRASY SAALGLEFLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGGAAGGA GATGAGGGGG CAATTGGATT CCGGAGGGAA ATAGCCCGAG GGGGCGGCGG 60
AGCCCATGGA GTCCCCTCCG GTGGTGGTCG GGCAGCGGGT ACGGGCCGTG CTGGATGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025754--TRC8_N_dom
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13705--TRC8_N
PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002401	Ailuropoda melanoleuca	70.68	0.00e+00	911.00
IUUC-Apl-004214	Anas platyrhynchos	79.30	0.00e+00	876.00
IUUC-Aca-005326	Anolis carolinensis	73.37	0.00e+00	890.00
IUUC-Ame-011687	Astyanax mexicanus	65.26	0.00e+00	832.00
IUUC-Bta-013394	Bos taurus	70.75	0.00e+00	941.00
IUUC-Cja-019499	Callithrix jacchus	70.25	0.00e+00	943.00
IUUC-Cfa-020357	Canis familiaris	70.85	0.00e+00	921.00
IUUC-Cpo-021924	Cavia porcellus	73.77	0.00e+00	931.00
IUUC-Csa-023513	Chlorocebus sabaeus	70.40	0.00e+00	937.00
IUUC-Cho-024285	Choloepus hoffmanni	65.85	0.00e+00	805.00
IUUC-Cin-025223	Ciona intestinalis	51.84	2.00e-72	265.00
IUUC-Csv-026018	Ciona savignyi	46.37	1.00e-62	233.00
IUUC-Dre-028660	Danio rerio	65.97	0.00e+00	761.00
IUUC-Dno-029463	Dasypus novemcinctus	78.14	1.00e-117	416.00
IUUC-Dor-030728	Dipodomys ordii	71.66	0.00e+00	880.00
IUUC-Dme-032186	Drosophila melanogaster	48.20	5.00e-101	362.00
IUUC-Ete-032368	Echinops telfairi	69.30	0.00e+00	918.00
IUUC-Eca-034325	Equus caballus	70.45	0.00e+00	917.00
IUUC-Fca-035537	Felis catus	72.07	0.00e+00	912.00
IUUC-Fal-037459	Ficedula albicollis	78.29	0.00e+00	856.00
IUUC-Gmo-039442	Gadus morhua	80.92	6.00e-97	348.00
IUUC-Gga-041071	Gallus gallus	74.76	0.00e+00	895.00
IUUC-Gac-042483	Gasterosteus aculeatus	65.21	0.00e+00	877.00
IUUC-Ggo-044672	Gorilla gorilla	70.55	0.00e+00	938.00
IUUC-Hsa-045836	Homo sapiens	70.25	0.00e+00	919.00
IUUC-Itr-048588	Ictidomys tridecemlineatus	72.71	0.00e+00	955.00
IUUC-Lch-050073	Latimeria chalumnae	72.07	0.00e+00	956.00
IUUC-Loc-052908	Lepisosteus oculatus	69.30	0.00e+00	915.00
IUUC-Laf-053519	Loxodonta africana	69.55	0.00e+00	940.00
IUUC-Mga-059922	Meleagris gallopavo	78.16	0.00e+00	863.00
IUUC-Mmr-061452	Microcebus murinus	69.76	0.00e+00	915.00
IUUC-Mdo-062412	Monodelphis domestica	71.12	0.00e+00	920.00
IUUC-Mmu-063147	Mus musculus	72.96	0.00e+00	936.00
IUUC-Mpu-065929	Mustela putorius furo	70.19	0.00e+00	917.00
IUUC-Mlu-067899	Myotis lucifugus	70.10	0.00e+00	912.00
IUUC-Nle-070083	Nomascus leucogenys	70.55	0.00e+00	939.00
IUUC-Opr-070461	Ochotona princeps	69.85	0.00e+00	942.00
IUUC-Ont-072256	Oreochromis niloticus	61.91	0.00e+00	866.00
IUUC-Oan-073150	Ornithorhynchus anatinus	75.35	0.00e+00	832.00
IUUC-Ocu-073748	Oryctolagus cuniculus	68.96	0.00e+00	902.00
IUUC-Oga-088565	Otolemur garnettii	71.04	0.00e+00	934.00
IUUC-Oar-089432	Ovis aries	73.93	0.00e+00	930.00
IUUC-Ptr-091422	Pan troglodytes	70.70	0.00e+00	940.00
IUUC-Pan-092331	Papio anubis	70.40	0.00e+00	938.00
IUUC-Psi-092933	Pelodiscus sinensis	77.76	0.00e+00	843.00
IUUC-Pfo-097466	Poecilia formosa	62.76	0.00e+00	865.00
IUUC-Pab-098702	Pongo abelii	70.55	0.00e+00	937.00
IUUC-Pca-100125	Procavia capensis	70.23	0.00e+00	924.00
IUUC-Pva-102628	Pteropus vampyrus	70.51	0.00e+00	919.00
IUUC-Rno-104886	Rattus norvegicus	72.74	0.00e+00	941.00
IUUC-Sha-106702	Sarcophilus harrisii	70.53	0.00e+00	918.00
IUUC-Ssc-116164	Sus scrofa	70.90	0.00e+00	937.00
IUUC-Tgu-116829	Taeniopygia guttata	76.05	0.00e+00	875.00
IUUC-Tru-118557	Takifugu rubripes	64.93	0.00e+00	841.00
IUUC-Tsy-119399	Tarsius syrichta	72.22	1.00e-154	539.00
IUUC-Tni-120006	Tetraodon nigroviridis	58.95	0.00e+00	723.00
IUUC-Tbe-127664	Tupaia belangeri	69.92	0.00e+00	904.00
IUUC-Ttr-129144	Tursiops truncatus	70.31	0.00e+00	941.00
IUUC-Vpa-130226	Vicugna pacos	70.60	0.00e+00	938.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence