iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tbe-127373

UUCD1 version

UUC-TuB-00179

Ensembl Protein ID

ENSTBEP00000009651.1

UniProt Accession

A0A077B9N5; A0A077B9N5_TUPBE

Genbank Protein ID

AIL01926.1

Protein Name

TRIM5-3 alpha isoform

Genbank Nucleotide ID

KJ697759

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTBEG00000011188.1	ENSTBET00000011173.1	ENSTBEP00000009651.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.10e-07	31.9	15	60
E3 activity/RING/U-box	1.70e-07	30.9	9	84

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl..qkwpglknssskefrCPlCr 46
           C+iCle + + p +l+CgH f+++C+  ++   l   + +e  CP+Cr
   Q: 15   CPICLELLTE-PQSLDCGHSFCQSCItaNHT-KLTVGQEGESCCPVCR 60
           ********99.***************87555.6788899********8 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwl......asggktcPvtrqplteedlvPnltlrrliqawcee 71
           v ee  CpI lel ++P  l +G+++ +s+I          ++g++ cPv+r + ++ +l Pn  l +++++ + +
   Q: 9    VKEEVTCPICLELLTEPQSLDCGHSFCQSCITANHtkltvgQEGESCCPVCRVSYQPGSLRPNRHLANIVEKLRVA 84
           7899***************************864336666666666********************9999886655 PP

Organism

Tupaia belangeri

Protein Sequence
(Fasta)

MALAILVDVK EEVTCPICLE LLTEPQSLDC GHSFCQSCIT ANHTKLTVGQ EGESCCPVCR 60
VSYQPGSLRP NRHLANIVEK LRVANLSPEE GQKVDCCARH GEKLLLFCKQ DGKVICWLCE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTTGG CCATCCTGGT GGATGTAAAG GAGGAGGTGA CCTGCCCCAT TTGCCTGGAG 60
CTCCTGACAG AACCCCAGAG CCTAGACTGT GGACACAGCT TCTGCCAGTC CTGCATCACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0479--Metal-binding
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR003877--SPRY_dom
IPR032917--TRIM5
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0051607--P:defense response to virus
GO:0045087--P:innate immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006191	Arabidopsis lyrata	33.73	9.00e-08	48.10
IUUC-Bci-013931	Botrytis cinerea	31.68	5.00e-07	49.70
IUUC-Cpo-021972	Cavia porcellus	54.80	5.00e-72	263.00
IUUC-Cho-024416	Choloepus hoffmanni	55.60	1.00e-76	280.00
IUUC-Cme-027197	Cyanidioschyzon merolae	33.65	2.00e-06	47.80
IUUC-Itr-048793	Ictidomys tridecemlineatus	57.60	2.00e-73	268.00
IUUC-Meu-056452	Macropus eugenii	50.00	2.00e-34	138.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence