iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-134311

Ensembl Protein ID

ENSXMAP00000003215.1

UniProt Accession

M3ZLX3; M3ZLX3_XIPMA

Genbank Protein ID

ENSXMAP00000003215

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AGAJ01020642

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000003197.1	ENSXMAT00000003220.1	ENSXMAP00000003215.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.20e-12	46.8	94	151

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 94   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 151
           67899************************.*********98..788899*********997 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MGQQVGRVGE VTSTALQPPQ PHASQPHQGK GSRGSVAGRR PREPGCSTMM PPVRTTVTNA 60
PDPGINIFTQ HSVLTEAVRW SSKENLLGAT ESDPNLFVAL YDFVASGDNT LSITKGEKLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCAGAACAC CGGTGTTTGC GCTGGAGCTG ACAGGGGGCC GAGGCGAGCC CCCCGCCTTG 60
TGCAACACAT CCTTCTATTC TGCGGTAAAG ATGGCGGCGT CAGAGGGGGC GCGCAGCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002263	Ailuropoda melanoleuca	67.01	0.00e+00	1337.00
IUUC-Apl-003389	Anas platyrhynchos	66.93	0.00e+00	1294.00
IUUC-Ame-010629	Astyanax mexicanus	65.60	0.00e+00	1184.00
IUUC-Bta-013370	Bos taurus	63.28	0.00e+00	1333.00
IUUC-Cja-018894	Callithrix jacchus	65.55	0.00e+00	1337.00
IUUC-Cfa-020398	Canis familiaris	83.70	0.00e+00	1048.00
IUUC-Cpo-022367	Cavia porcellus	65.96	0.00e+00	1294.00
IUUC-Csa-023386	Chlorocebus sabaeus	66.58	0.00e+00	1332.00
IUUC-Cho-024714	Choloepus hoffmanni	78.01	0.00e+00	1119.00
IUUC-Dre-027741	Danio rerio	76.74	0.00e+00	1563.00
IUUC-Dno-029246	Dasypus novemcinctus	63.95	0.00e+00	1310.00
IUUC-Dor-030416	Dipodomys ordii	59.19	0.00e+00	1177.00
IUUC-Ete-032899	Echinops telfairi	92.98	1.00e-124	441.00
IUUC-Eca-033387	Equus caballus	66.67	0.00e+00	1316.00
IUUC-Eeu-035058	Erinaceus europaeus	62.15	0.00e+00	1247.00
IUUC-Fca-036578	Felis catus	71.72	0.00e+00	1113.00
IUUC-Fal-037491	Ficedula albicollis	67.01	0.00e+00	1358.00
IUUC-Gmo-038509	Gadus morhua	80.61	0.00e+00	1345.00
IUUC-Gga-040638	Gallus gallus	65.95	0.00e+00	1320.00
IUUC-Gac-042550	Gasterosteus aculeatus	82.92	0.00e+00	1683.00
IUUC-Ggo-044487	Gorilla gorilla	62.96	0.00e+00	1332.00
IUUC-Hsa-046636	Homo sapiens	62.96	0.00e+00	1332.00
IUUC-Itr-048685	Ictidomys tridecemlineatus	66.47	0.00e+00	1326.00
IUUC-Lch-049530	Latimeria chalumnae	67.83	0.00e+00	1337.00
IUUC-Loc-051933	Lepisosteus oculatus	76.09	0.00e+00	1494.00
IUUC-Laf-053802	Loxodonta africana	63.53	0.00e+00	1383.00
IUUC-Mcc-054836	Macaca mulatta	63.20	0.00e+00	1335.00
IUUC-Mga-059277	Meleagris gallopavo	67.22	0.00e+00	1327.00
IUUC-Mmr-061206	Microcebus murinus	63.43	0.00e+00	1295.00
IUUC-Mdo-062281	Monodelphis domestica	77.42	0.00e+00	1055.00
IUUC-Mmu-063847	Mus musculus	63.07	0.00e+00	1313.00
IUUC-Mpu-066309	Mustela putorius furo	75.37	0.00e+00	1063.00
IUUC-Mlu-068070	Myotis lucifugus	66.75	0.00e+00	1328.00
IUUC-Nle-070062	Nomascus leucogenys	75.40	0.00e+00	1055.00
IUUC-Ont-072440	Oreochromis niloticus	85.24	0.00e+00	1806.00
IUUC-Oan-073526	Ornithorhynchus anatinus	72.98	0.00e+00	1219.00
IUUC-Ocu-074051	Oryctolagus cuniculus	66.75	0.00e+00	1296.00
IUUC-Ola-086752	Oryzias latipes	98.48	0.00e+00	934.00
IUUC-Oga-088767	Otolemur garnettii	61.11	0.00e+00	1136.00
IUUC-Oar-089800	Ovis aries	66.78	0.00e+00	1326.00
IUUC-Ptr-090857	Pan troglodytes	75.40	0.00e+00	1058.00
IUUC-Pan-092279	Papio anubis	64.19	0.00e+00	1345.00
IUUC-Psi-093573	Pelodiscus sinensis	66.81	0.00e+00	1299.00
IUUC-Pfo-096543	Poecilia formosa	96.22	0.00e+00	1857.00
IUUC-Pab-097949	Pongo abelii	63.25	0.00e+00	1313.00
IUUC-Pca-100370	Procavia capensis	59.48	0.00e+00	887.00
IUUC-Pva-103220	Pteropus vampyrus	57.44	0.00e+00	1110.00
IUUC-Rno-105924	Rattus norvegicus	62.86	0.00e+00	1314.00
IUUC-Sha-107114	Sarcophilus harrisii	75.66	0.00e+00	1101.00
IUUC-Sbi-114480	Sorghum bicolor	33.33	3.00e-24	107.00
IUUC-Ssc-115968	Sus scrofa	62.94	0.00e+00	1338.00
IUUC-Tgu-117301	Taeniopygia guttata	67.48	0.00e+00	1341.00
IUUC-Tru-118410	Takifugu rubripes	83.24	0.00e+00	1822.00
IUUC-Tni-119991	Tetraodon nigroviridis	82.28	0.00e+00	1827.00
IUUC-Tca-121389	Theobroma cacao	33.33	1.00e-23	105.00
IUUC-Tbe-127362	Tupaia belangeri	70.82	0.00e+00	1162.00
IUUC-Ttr-129291	Tursiops truncatus	67.33	0.00e+00	1325.00
IUUC-Vpa-130800	Vicugna pacos	77.04	0.00e+00	1160.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence