iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073670

UUCD1 version

UUC-OrA-00681

Ensembl Protein ID

ENSOANP00000021654.2

UniProt Accession

F7FNZ8; F7FNZ8_ORNAN

Protein Name

Uncharacterized protein

Gene Name

TAF5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000013730.2	ENSOANT00000021657.2	ENSOANP00000021654.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-41	138.6	414	450
UBD/Beta-Prp	3.30e-68	230.3	174	477

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gHtd +t+laf +d  l++s+s D++++vWD+r+ ++
   Q: 414  GHTDNITSLAFsPDsSLVASASMDNSVRVWDIRSAHC 450
           8***********9999***************999876 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkl..............................lrslsgheaevtavkfspdgki 66
           h ++ ++   +spd++lla+g++d+++k+w+++++kl                              +++l gh ++v+ ++f +dg+ 
   Q: 174  HTEQLLNTAEISPDGRLLAAGFDDSCVKLWSLRSQKLkaephcvdvarvhlacdvldaeeedgagteMKTLRGHCGPVYGTRFLSDGSG 262
           45556677889****************************************************************************** PP
   S: 67   lvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsG 155
           l+++seD  i+ wdl t++ ++ ++gh++ v++l++sp + +++s+shdrt+r+w  +  + l+ + +gh + v cv++hp++n+l++G
   Q: 263  LLSCSEDTSIRYWDLGTFTNTVLYQGHSYPVWDLDVSPCSLYFASASHDRTARLWSPDRTYPLR-VYAGHLADVDCVRFHPNSNYLATG 350
           ****************************************************************.************************ PP
   S: 156  slDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDg 244
           s+D+tvrlW+ ++g+ +r +tg h ++v sl+f++ngk+l+s+++d+++klwdl  g+  ++l+ghtdn++s++fsp++ +++s+s+D+
   Q: 351  STDKTVRLWSAQQGSSVRLFTG-HRGPVLSLAFSPNGKFLASAGEDQRLKLWDLAGGTPFKELRGHTDNITSLAFSPDSSLVASASMDN 438
           *********************9.****************************************************************** PP
   S: 245  siriWdlrsgdllktlqlhn...........ssvisvav 272
           s+r+Wd+rs  +  +  ++            ssv sv++
   Q: 439  SVRVWDIRSAHCGAAADGSSgelvgvyagqaSSVLSVQF 477
           *****9999999999888886666666655566666665 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MPLLYPLFVY LHLSMVQSGL KSTVDSFYSR FHGLFLQNAG QKDVIEQLQT ALTPQDILAN 60
LTLRAFLDNK YVVRLQEDSY NFLLRYLQSD DNGALVQVLT LHIHLDVQPA KRTDYQLYAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGCGGGGA GGCCCTTCAA GCCGTTTTTG GTGCCGTTGC AGATTCCGAC TCCCAGCACA 60
GCCACGAAGT GATGCCTCTC CTGTATCCCC TGTTCGTCTA CCTCCACCTG AGCATGGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR023302--Pept_S9A_N
IPR007582--TFIID_NTD2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	83.30	0.00e+00	807.00
IUUC-Apl-003636	Anas platyrhynchos	83.70	0.00e+00	873.00
IUUC-Aca-004229	Anolis carolinensis	83.90	0.00e+00	853.00
IUUC-Ame-010599	Astyanax mexicanus	66.67	0.00e+00	684.00
IUUC-Bta-013404	Bos taurus	81.89	0.00e+00	786.00
IUUC-Cja-019643	Callithrix jacchus	82.70	0.00e+00	820.00
IUUC-Cfa-020913	Canis familiaris	83.10	0.00e+00	823.00
IUUC-Cpo-021777	Cavia porcellus	82.90	0.00e+00	793.00
IUUC-Csa-024184	Chlorocebus sabaeus	83.30	0.00e+00	831.00
IUUC-Cho-024638	Choloepus hoffmanni	84.10	0.00e+00	811.00
IUUC-Cin-025618	Ciona intestinalis	34.99	3.00e-78	285.00
IUUC-Csv-025874	Ciona savignyi	34.32	2.00e-78	286.00
IUUC-Dre-028817	Danio rerio	66.93	0.00e+00	665.00
IUUC-Dno-029969	Dasypus novemcinctus	81.12	0.00e+00	810.00
IUUC-Dor-031117	Dipodomys ordii	82.90	0.00e+00	819.00
IUUC-Ete-032712	Echinops telfairi	82.70	0.00e+00	800.00
IUUC-Eca-033742	Equus caballus	83.10	0.00e+00	822.00
IUUC-Eeu-035096	Erinaceus europaeus	81.93	0.00e+00	835.00
IUUC-Fca-035769	Felis catus	83.10	0.00e+00	848.00
IUUC-Fal-036645	Ficedula albicollis	83.19	0.00e+00	816.00
IUUC-Gmo-038636	Gadus morhua	64.82	0.00e+00	639.00
IUUC-Gga-040144	Gallus gallus	83.50	0.00e+00	849.00
IUUC-Gac-041716	Gasterosteus aculeatus	67.26	0.00e+00	669.00
IUUC-Ggo-044568	Gorilla gorilla	82.70	0.00e+00	821.00
IUUC-Hsa-046178	Homo sapiens	82.70	0.00e+00	821.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	81.49	0.00e+00	829.00
IUUC-Lch-050501	Latimeria chalumnae	74.79	0.00e+00	727.00
IUUC-Loc-052895	Lepisosteus oculatus	67.54	3.00e-177	614.00
IUUC-Laf-053950	Loxodonta africana	81.49	0.00e+00	791.00
IUUC-Mcc-055450	Macaca mulatta	82.49	0.00e+00	816.00
IUUC-Meu-056182	Macropus eugenii	84.71	0.00e+00	839.00
IUUC-Mga-059619	Meleagris gallopavo	83.70	0.00e+00	852.00
IUUC-Mmr-061074	Microcebus murinus	82.90	0.00e+00	840.00
IUUC-Mdo-062307	Monodelphis domestica	83.76	0.00e+00	653.00
IUUC-Mmu-063226	Mus musculus	81.49	0.00e+00	796.00
IUUC-Mpu-066016	Mustela putorius furo	83.30	0.00e+00	807.00
IUUC-Mlu-067257	Myotis lucifugus	80.59	0.00e+00	825.00
IUUC-Nle-070139	Nomascus leucogenys	82.90	0.00e+00	823.00
IUUC-Opr-070243	Ochotona princeps	81.09	0.00e+00	818.00
IUUC-Ont-072686	Oreochromis niloticus	68.64	0.00e+00	694.00
IUUC-Ocu-074525	Oryctolagus cuniculus	82.49	0.00e+00	823.00
IUUC-Ola-086524	Oryzias latipes	69.23	0.00e+00	726.00
IUUC-Oga-088540	Otolemur garnettii	83.30	0.00e+00	825.00
IUUC-Oar-089793	Ovis aries	78.27	0.00e+00	724.00
IUUC-Ptr-091154	Pan troglodytes	82.70	0.00e+00	821.00
IUUC-Pan-092759	Papio anubis	82.49	0.00e+00	816.00
IUUC-Psi-094008	Pelodiscus sinensis	80.68	0.00e+00	838.00
IUUC-Pma-094593	Petromyzon marinus	49.19	1.00e-123	436.00
IUUC-Pfo-097409	Poecilia formosa	66.67	0.00e+00	674.00
IUUC-Pab-097946	Pongo abelii	77.06	0.00e+00	761.00
IUUC-Pca-100727	Procavia capensis	82.29	0.00e+00	797.00
IUUC-Pva-103211	Pteropus vampyrus	79.84	0.00e+00	786.00
IUUC-Rno-105236	Rattus norvegicus	82.49	0.00e+00	783.00
IUUC-Sha-106833	Sarcophilus harrisii	83.40	0.00e+00	828.00
IUUC-Sar-113381	Sorex araneus	82.90	0.00e+00	847.00
IUUC-Ssc-116421	Sus scrofa	83.10	0.00e+00	848.00
IUUC-Tgu-117143	Taeniopygia guttata	83.10	0.00e+00	870.00
IUUC-Tru-118680	Takifugu rubripes	67.25	0.00e+00	710.00
IUUC-Tsy-119622	Tarsius syrichta	73.04	0.00e+00	664.00
IUUC-Tni-120131	Tetraodon nigroviridis	67.65	0.00e+00	709.00
IUUC-Tbe-127656	Tupaia belangeri	79.78	1.00e-75	276.00
IUUC-Ttr-129171	Tursiops truncatus	83.50	0.00e+00	805.00
IUUC-Xtr-132241	Xenopus tropicalis	77.13	0.00e+00	779.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence