iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044739

UUCD1 version

UUC-GoG-00785

Ensembl Protein ID

ENSGGOP00000020785.1

UniProt Accession

G3QQR3; G3QQR3_GORGO

Protein Name

Uncharacterized protein

Gene Name

FBXW4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000005039.2	ENSGGOT00000005064.2	ENSGGOP00000004937.2
ENSGGOG00000005039.2	ENSGGOT00000022150.1	ENSGGOP00000020785.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-17	63.1	201	234
UBD/Beta-Prp	4.20e-40	138.2	272	410

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           H+ +v+c++  ++++vsGs+D t kvW l +g+l
   Q: 201  HEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRL 234
           99*******9449***************999875 PP

UBD/Beta-Prp

   S: 161  vrlWdlktgkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlq..tgecvrtlng.htdnvksvrfspnderlvsgs.sDg 244
           +r+Wdl++g+l+++l ++  +    l++ +++ + l+s+++d++v++wdl+    +cv+++++ h+++ ++++++  +++l++gs   g
   Q: 272  LRIWDLNSGQLMTHLGSDFPPGAGVLDVMYESpFTLLSCGYDTYVRYWDLRtsVRKCVMEWEEpHDSTLYCLQTD-GNHLLATGSsYYG 359
           79*************99999*******9999989*****************88789*****9999**********.999999999789* PP
   S: 245  siriWdlrsgdllktlqlhn.ssvisvavlsfgdnvlvlgsedskvniwklk 295
           ++r+Wd r++ +l+++ l+    +++v +l+++ ++l+++ +  ++++++++
   Q: 360  VVRLWDRRQRACLHAFPLTStPLSSPVYCLRLTTKHLYAALS-YNLHVLDFQ 410
           ******************99667889**********999866.467777665 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAAAAGEEEE EEEAAREAAA RPAAGPALWR LPEELLLLIC SYLDIRALGR LAQVCRWLRR 60
FTSCDLLWRR IARASLNSGF TRLGTDLMTS VPVKERVKVS QNWRLGRCRE GILLKWRCSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGTCGC CTCCTCCCGG GGCGGCGGCG GTGGCGGCTC GCGCTGGGCT CCGCGTCGGG 60
CNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNCCCCG GGAACGGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	97.59	0.00e+00	760.00
IUUC-Apl-003837	Anas platyrhynchos	72.05	1.00e-141	495.00
IUUC-Aca-004776	Anolis carolinensis	67.92	8.00e-140	489.00
IUUC-Ame-010651	Astyanax mexicanus	62.73	2.00e-114	405.00
IUUC-Bta-013495	Bos taurus	95.99	0.00e+00	717.00
IUUC-Cja-018901	Callithrix jacchus	99.19	0.00e+00	732.00
IUUC-Cfa-021251	Canis familiaris	96.52	0.00e+00	752.00
IUUC-Cpo-021750	Cavia porcellus	94.77	0.00e+00	649.00
IUUC-Csa-024026	Chlorocebus sabaeus	98.92	0.00e+00	765.00
IUUC-Cho-024496	Choloepus hoffmanni	75.61	3.00e-158	551.00
IUUC-Cin-025142	Ciona intestinalis	31.62	9.00e-25	106.00
IUUC-Csv-025883	Ciona savignyi	37.12	5.00e-66	244.00
IUUC-Dre-027447	Danio rerio	59.11	2.00e-132	465.00
IUUC-Dno-029572	Dasypus novemcinctus	82.07	3.00e-173	601.00
IUUC-Dor-030982	Dipodomys ordii	88.62	0.00e+00	670.00
IUUC-Ete-032917	Echinops telfairi	95.38	0.00e+00	653.00
IUUC-Eca-033969	Equus caballus	97.56	0.00e+00	720.00
IUUC-Eeu-034850	Erinaceus europaeus	85.64	0.00e+00	649.00
IUUC-Fca-036182	Felis catus	92.25	0.00e+00	689.00
IUUC-Fal-037391	Ficedula albicollis	68.53	3.00e-147	514.00
IUUC-Gmo-038632	Gadus morhua	56.77	9.00e-128	449.00
IUUC-Gga-040783	Gallus gallus	73.05	4.00e-160	557.00
IUUC-Gac-042314	Gasterosteus aculeatus	56.33	1.00e-111	395.00
IUUC-Hsa-046705	Homo sapiens	99.46	0.00e+00	732.00
IUUC-Itr-048014	Ictidomys tridecemlineatus	98.62	1.00e-172	598.00
IUUC-Loc-052397	Lepisosteus oculatus	65.19	3.00e-139	488.00
IUUC-Laf-054544	Loxodonta africana	94.64	0.00e+00	658.00
IUUC-Meu-056363	Macropus eugenii	59.38	1.00e-102	365.00
IUUC-Mga-059275	Meleagris gallopavo	73.35	4.00e-143	500.00
IUUC-Mmr-060906	Microcebus murinus	98.92	0.00e+00	763.00
IUUC-Mdo-062400	Monodelphis domestica	77.81	1.00e-175	608.00
IUUC-Mmu-063556	Mus musculus	93.50	0.00e+00	719.00
IUUC-Mpu-066500	Mustela putorius furo	97.33	0.00e+00	758.00
IUUC-Mlu-068074	Myotis lucifugus	97.54	0.00e+00	663.00
IUUC-Nle-069601	Nomascus leucogenys	99.73	0.00e+00	766.00
IUUC-Opr-070904	Ochotona princeps	87.94	2.00e-147	514.00
IUUC-Ont-072679	Oreochromis niloticus	56.51	8.00e-121	426.00
IUUC-Oan-073434	Ornithorhynchus anatinus	73.36	2.00e-84	304.00
IUUC-Ocu-074649	Oryctolagus cuniculus	95.93	0.00e+00	732.00
IUUC-Ola-087336	Oryzias latipes	49.48	3.00e-104	371.00
IUUC-Oga-088590	Otolemur garnettii	95.39	0.00e+00	707.00
IUUC-Oar-090178	Ovis aries	93.33	0.00e+00	669.00
IUUC-Pan-092881	Papio anubis	99.19	0.00e+00	764.00
IUUC-Pfo-096176	Poecilia formosa	56.25	2.00e-113	402.00
IUUC-Pab-098285	Pongo abelii	99.73	0.00e+00	767.00
IUUC-Pca-100888	Procavia capensis	91.98	0.00e+00	695.00
IUUC-Pva-102184	Pteropus vampyrus	82.93	6.00e-177	613.00
IUUC-Rno-105668	Rattus norvegicus	93.77	0.00e+00	724.00
IUUC-Sha-106629	Sarcophilus harrisii	77.64	4.00e-154	536.00
IUUC-Ssc-116183	Sus scrofa	98.13	0.00e+00	766.00
IUUC-Tgu-116630	Taeniopygia guttata	71.73	2.00e-167	581.00
IUUC-Tru-118761	Takifugu rubripes	52.37	4.00e-117	414.00
IUUC-Tni-120651	Tetraodon nigroviridis	51.98	3.00e-59	220.00
IUUC-Ttr-128582	Tursiops truncatus	95.19	0.00e+00	708.00
IUUC-Vpa-130431	Vicugna pacos	76.19	2.00e-97	348.00
IUUC-Xtr-132655	Xenopus tropicalis	66.40	8.00e-148	516.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence