iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-068074

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02031063

Gene Name

FBXW4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000004952.2	ENSMLUT00000004951.2	ENSMLUP00000004513.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.20e-19	66.9	114	147
UBD/Beta-Prp	1.20e-40	139.6	185	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           H+ +v+c++  ++++vsGs+D t kvW+l +g+l
   Q: 114  HEQEVNCVDCRGGIIVSGSRDRTAKVWSLASGRL 147
           99*******9669****************99985 PP

UBD/Beta-Prp

   S: 161  vrlWdlktgkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlq..tgecvrtlng.htdnvksvrfspnderlvsgs.sDg 244
           +r+Wdl++g+l+++l ++  +    l++ +++ + l+s+++d++v++wdl+    +cv+++++ h+++ ++++++  +++l++gs   g
   Q: 185  LRIWDLNSGQLMTHLGSDFPPGAGVLDLMYESpFTLLSCGYDTYVRYWDLRasVRKCVMEWEEpHDSTLYCLQTD-GNHLLATGSsYYG 272
           79*************999999******9999989*****************99899*****9999**********.999999999789* PP
   S: 245  siriWdlrsgdllktlqlhn.ssvisvavlsfgdnvlvlgsedskvniwklk 295
           ++r+Wd r++ +l+++ l+    +++v +l+f+ ++l+++ +  ++++++++
   Q: 273  VVRLWDRRQRACLHAFPLTStPLSSPVYCLRFTTKHLYAALS-YNLHVLDFQ 323
           ******************99667889***********99866.467777765 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MASVPVKERV KVSQNWRLGR CREGILLKWR CSQMPWMQLE GDSLYISQAN FILAYQFRPD 60
GASLNRRPLG VFAGHDEDVC HFVLANSHII SAGGDGKIGV HKIHSTFTVK YSAHEQEVNC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCAGTG TACCAGTAAA AGAACGAGTG AAGGTGTCTC AAAACTGGAG GTTGGGGCGC 60
TGCCGAGAGG GGATTCTGTT GAAGTGGAGA TGCAGGTAAG TAGCCTTTTG ACTCTTAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0051216--P:cartilage development
GO:0042733--P:embryonic digit morphogenesis
GO:0002053--P:positive regulation of mesenchymal cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	98.77	0.00e+00	669.00
IUUC-Apl-003837	Anas platyrhynchos	71.91	5.00e-143	499.00
IUUC-Aca-004776	Anolis carolinensis	68.94	1.00e-121	429.00
IUUC-Ame-010651	Astyanax mexicanus	62.11	3.00e-114	404.00
IUUC-Bta-013495	Bos taurus	96.92	0.00e+00	632.00
IUUC-Cja-018901	Callithrix jacchus	97.54	0.00e+00	635.00
IUUC-Cfa-021251	Canis familiaris	97.85	0.00e+00	662.00
IUUC-Cpo-021750	Cavia porcellus	93.85	0.00e+00	645.00
IUUC-Csa-024026	Chlorocebus sabaeus	97.23	0.00e+00	664.00
IUUC-Cho-024496	Choloepus hoffmanni	73.85	1.00e-134	473.00
IUUC-Cin-025142	Ciona intestinalis	31.91	4.00e-17	81.60
IUUC-Csv-025883	Ciona savignyi	38.10	2.00e-62	233.00
IUUC-Dre-027447	Danio rerio	61.80	3.00e-116	411.00
IUUC-Dno-029572	Dasypus novemcinctus	87.77	5.00e-167	580.00
IUUC-Dor-030982	Dipodomys ordii	96.92	1.00e-170	592.00
IUUC-Dme-031804	Drosophila melanogaster	23.01	7.00e-12	65.10
IUUC-Ete-032917	Echinops telfairi	95.08	0.00e+00	652.00
IUUC-Eca-033969	Equus caballus	97.54	0.00e+00	635.00
IUUC-Eeu-034850	Erinaceus europaeus	85.23	4.00e-165	573.00
IUUC-Fca-036182	Felis catus	98.46	0.00e+00	668.00
IUUC-Fal-037391	Ficedula albicollis	71.34	9.00e-138	483.00
IUUC-Gmo-038632	Gadus morhua	59.81	3.00e-113	401.00
IUUC-Gga-040783	Gallus gallus	73.35	6.00e-144	503.00
IUUC-Gac-042314	Gasterosteus aculeatus	59.08	2.00e-96	345.00
IUUC-Ggo-044739	Gorilla gorilla	97.54	0.00e+00	664.00
IUUC-Hsa-046705	Homo sapiens	97.23	0.00e+00	634.00
IUUC-Itr-048014	Ictidomys tridecemlineatus	97.58	2.00e-169	587.00
IUUC-Loc-052397	Lepisosteus oculatus	69.25	7.00e-129	453.00
IUUC-Laf-054544	Loxodonta africana	96.64	0.00e+00	657.00
IUUC-Meu-056363	Macropus eugenii	58.15	9.00e-102	363.00
IUUC-Mga-059275	Meleagris gallopavo	73.35	5.00e-144	503.00
IUUC-Mmr-060906	Microcebus murinus	97.23	0.00e+00	662.00
IUUC-Mdo-062400	Monodelphis domestica	77.23	2.00e-154	538.00
IUUC-Mmu-063556	Mus musculus	92.31	0.00e+00	632.00
IUUC-Mpu-066500	Mustela putorius furo	98.46	0.00e+00	667.00
IUUC-Nle-069601	Nomascus leucogenys	97.54	0.00e+00	664.00
IUUC-Opr-070904	Ochotona princeps	85.29	1.00e-119	422.00
IUUC-Ont-072679	Oreochromis niloticus	57.63	5.00e-111	394.00
IUUC-Oan-073434	Ornithorhynchus anatinus	73.26	8.00e-68	249.00
IUUC-Ocu-074649	Oryctolagus cuniculus	95.38	0.00e+00	653.00
IUUC-Ola-087336	Oryzias latipes	51.09	3.00e-89	322.00
IUUC-Oga-088590	Otolemur garnettii	93.23	5.00e-176	610.00
IUUC-Oar-090178	Ovis aries	97.23	0.00e+00	629.00
IUUC-Pan-092881	Papio anubis	97.54	0.00e+00	664.00
IUUC-Pfo-096176	Poecilia formosa	58.64	2.00e-99	355.00
IUUC-Pab-098285	Pongo abelii	97.54	0.00e+00	665.00
IUUC-Pca-100888	Procavia capensis	90.46	2.00e-172	597.00
IUUC-Pva-102184	Pteropus vampyrus	81.23	2.00e-152	531.00
IUUC-Rno-105668	Rattus norvegicus	92.31	0.00e+00	632.00
IUUC-Sha-106629	Sarcophilus harrisii	77.64	6.00e-155	540.00
IUUC-Ssc-116183	Sus scrofa	98.46	0.00e+00	668.00
IUUC-Tgu-116630	Taeniopygia guttata	71.65	3.00e-142	498.00
IUUC-Tru-118761	Takifugu rubripes	54.55	1.00e-102	366.00
IUUC-Tni-120651	Tetraodon nigroviridis	51.98	1.00e-59	222.00
IUUC-Ttr-128582	Tursiops truncatus	96.00	1.00e-178	619.00
IUUC-Vpa-130431	Vicugna pacos	75.76	7.00e-97	347.00
IUUC-Xtr-132655	Xenopus tropicalis	67.71	2.00e-131	461.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence