iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004499

Ensembl Protein ID

ENSACAP00000001425.2

UniProt Accession

H9G577; H9G577_ANOCA

Protein Name

Uncharacterized protein

Gene Name

DDX58

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000001354.2	ENSACAT00000001459.2	ENSACAP00000001425.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	4.30e-10	39.9	9	72

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 9    lstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL..vqkegWfrefl 73
           l +++ ++ k+L ++++l+ y+  +l+   +e+i+  +    + +aae +L+ +  +   gWfr+fl
   Q: 9    LLRFRHYIQKTLNPVYILS-YMKDWLPDDMVEKIQGLK--DNPTTAAEIFLQSIveLTSDGWFRGFL 72
           6689***************.******************..7799**********99999******96 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MTAEEKENLL RFRHYIQKTL NPVYILSYMK DWLPDDMVEK IQGLKDNPTT AAEIFLQSIV 60
ELTSDGWFRG FLNALSAAGY TGLHHAIENW NFEMIENLAP HRALLNVIEP SLRVVDPEQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTGCCG AGGAGAAGGA GAACTTGCTC CGCTTCAGGC ATTACATCCA GAAGACCCTC 60
AACCCCGTCT ACATTCTGAG CTACATGAAG GACTGGCTCC CCGATGGTGA GCGTGTGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR031964--CARD_dom
IPR011545--DEAD/DEAH_box_helicase_dom
IPR011029--DEATH-like_dom
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00270--DEAD
PF00271--Helicase_C
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001898	Ailuropoda melanoleuca	46.64	0.00e+00	756.00
IUUC-Apl-003966	Anas platyrhynchos	48.31	0.00e+00	764.00
IUUC-Ago-007924	Ashbya gossypii	45.83	5.90e-01	29.30
IUUC-Ame-011950	Astyanax mexicanus	40.24	7.00e-91	328.00
IUUC-Bta-012489	Bos taurus	46.85	0.00e+00	769.00
IUUC-Cja-018716	Callithrix jacchus	46.83	0.00e+00	779.00
IUUC-Cfa-020269	Canis familiaris	47.34	0.00e+00	791.00
IUUC-Cpo-022507	Cavia porcellus	46.59	0.00e+00	754.00
IUUC-Csa-024209	Chlorocebus sabaeus	46.83	0.00e+00	787.00
IUUC-Cho-025104	Choloepus hoffmanni	44.50	2.00e-168	586.00
IUUC-Dno-028954	Dasypus novemcinctus	45.39	0.00e+00	706.00
IUUC-Eca-034039	Equus caballus	47.32	0.00e+00	775.00
IUUC-Eeu-035009	Erinaceus europaeus	44.20	7.00e-140	491.00
IUUC-Fca-036169	Felis catus	47.01	0.00e+00	779.00
IUUC-Fal-037579	Ficedula albicollis	50.68	0.00e+00	793.00
IUUC-Ggo-045318	Gorilla gorilla	45.46	0.00e+00	691.00
IUUC-Hsa-046671	Homo sapiens	46.94	0.00e+00	764.00
IUUC-Itr-047996	Ictidomys tridecemlineatus	43.88	0.00e+00	718.00
IUUC-Lch-050461	Latimeria chalumnae	42.04	0.00e+00	665.00
IUUC-Loc-052582	Lepisosteus oculatus	43.04	0.00e+00	678.00
IUUC-Laf-054324	Loxodonta africana	46.87	0.00e+00	751.00
IUUC-Mcc-055390	Macaca mulatta	46.51	0.00e+00	778.00
IUUC-Meu-056365	Macropus eugenii	51.65	4.00e-97	349.00
IUUC-Mla-059094	Melampsora laricipopulina	48.28	3.10e-01	30.00
IUUC-Mmr-061407	Microcebus murinus	46.17	0.00e+00	787.00
IUUC-Mmu-063939	Mus musculus	46.25	0.00e+00	770.00
IUUC-Mpu-066226	Mustela putorius furo	45.56	0.00e+00	686.00
IUUC-Mlu-068092	Myotis lucifugus	46.80	0.00e+00	738.00
IUUC-Opr-070246	Ochotona princeps	38.44	4.00e-68	253.00
IUUC-Oan-072742	Ornithorhynchus anatinus	47.89	0.00e+00	669.00
IUUC-Ocu-073959	Oryctolagus cuniculus	45.87	0.00e+00	748.00
IUUC-Oga-089173	Otolemur garnettii	44.62	0.00e+00	741.00
IUUC-Oar-089369	Ovis aries	46.21	0.00e+00	741.00
IUUC-Ptr-091032	Pan troglodytes	46.94	0.00e+00	764.00
IUUC-Pan-092383	Papio anubis	46.67	0.00e+00	778.00
IUUC-Psi-093432	Pelodiscus sinensis	52.09	0.00e+00	964.00
IUUC-Pab-098416	Pongo abelii	46.88	0.00e+00	716.00
IUUC-Pca-101006	Procavia capensis	42.72	5.00e-75	275.00
IUUC-Pva-102966	Pteropus vampyrus	47.01	0.00e+00	768.00
IUUC-Pgr-103529	Puccinia graminis	24.95	1.00e-22	102.00
IUUC-Rno-105059	Rattus norvegicus	49.49	6.00e-131	461.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	27.33	7.00e-04	40.80
IUUC-Sar-113202	Sorex araneus	41.61	3.00e-150	525.00
IUUC-Ssc-116120	Sus scrofa	47.18	0.00e+00	738.00
IUUC-Tgu-117314	Taeniopygia guttata	48.97	0.00e+00	816.00
IUUC-Tsy-119453	Tarsius syrichta	44.23	1.00e-110	394.00
IUUC-Ttr-128421	Tursiops truncatus	44.90	4.00e-167	581.00
IUUC-Vpa-130602	Vicugna pacos	45.66	0.00e+00	705.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence