iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090705

UUCD1 version

UUC-PaT-01070

Ensembl Protein ID

ENSPTRP00000027018.3

UniProt Accession

H2QNW5; H2QNW5_PANTR

Genbank Protein ID

JAA08786.1; JAA14801.1; JAA22556.1; JAA38774.1

Protein Name

SUMO1/sentrin/SMT3 specific peptidase 2

Genbank Nucleotide ID

AACZ03026744; GABF01007344; GABD01010544; GABE01005965

Gene Name

SENP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000015703.3	ENSPTRT00000029273.3	ENSPTRP00000027018.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/ULP	3.00e-55	187.0	396	558

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/ULP

   S: 2    svtnedlkcLeegeflnDviidfylkylvleklkkekverihifssffykklkqkerrrvktwtrkvdlfekdlifvpineaaHWslav 90
            +t+ d+++L++ ++lnD++i+fy++ l++e+ kk+ ++ +h+fs+ffy klk+ ++++vk+wt+ v+lfe+++i+vpi++++HWsl+v
   Q: 396  RITRGDIQTLKNYHWLNDEVINFYMN-LLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVV 483
           699***********************.999*********************************************************** PP
   S: 91   vcfkkksilllDSlrgasksnvvkklreylevevkkkskrefskeklkgsnpk...vpqQkNssDCGvyvlqyves 163
           ++++kk++ +lDS+ g++ ++++++l +yl++e+k+k++++++  ++ ++++k   +pqQ N+sDCG++ ++y+++
   Q: 484  IDLRKKCLKYLDSM-GQKGHRICEILLQYLQDESKTKRNIDLNLLEWTHHSMKpheIPQQLNGSDCGMFTCKYADY 558
           **************.********************************998888889*****************986 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MYRWLVRILG TIFRFCDRSV PPARALLKRR RSDSTLFSTV DTDEIPAKRP RLDCFIHQVK 60
NSLYNAASLF GFPFQMTTKP MVTSACNGTR NVAPSGEVFS NSSSCELTGS GSWNNMLKLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCCTCTGG TAGCCCTGGG GACGCTGTAT CTGTGGGCTC TTGAATCGCG TCACAAATCA 60
GCGACCGAAC TCTGGCGGTG GTGGTTAAGA CGGCGAAGGC GGCAGCGGCG GCGACAGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003653--Peptidase_C48_C

PROSITE

PS50600--ULP_PROTEASE

Pfam

PF02902--Peptidase_C48

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0005643--C:nuclear pore
GO:0005634--C:nucleus
GO:0016605--C:PML body
GO:0004175--F:endopeptidase activity
GO:0016929--F:SUMO-specific protease activity
GO:0045444--P:fat cell differentiation
GO:0007507--P:heart development
GO:0060711--P:labyrinthine layer development
GO:0035562--P:negative regulation of chromatin binding
GO:0043518--P:negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0031397--P:negative regulation of protein ubiquitination
GO:0031398--P:positive regulation of protein ubiquitination
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0031648--P:protein destabilization
GO:0016926--P:protein desumoylation
GO:0032875--P:regulation of DNA endoreduplication
GO:2000045--P:regulation of G1/S transition of mitotic cell cycle
GO:0060712--P:spongiotrophoblast layer development
GO:0060707--P:trophoblast giant cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001512	Ailuropoda melanoleuca	92.37	0.00e+00	1068.00
IUUC-Atr-003110	Amborella trichopoda	41.74	2.00e-42	167.00
IUUC-Apl-003602	Anas platyrhynchos	50.12	4.00e-113	401.00
IUUC-Aca-004819	Anolis carolinensis	61.92	2.00e-101	362.00
IUUC-Afl-008417	Aspergillus flavus	30.30	3.00e-30	127.00
IUUC-Aor-010104	Aspergillus oryzae	32.04	4.00e-29	120.00
IUUC-Ame-011519	Astyanax mexicanus	35.26	6.00e-76	278.00
IUUC-Bta-013157	Bos taurus	91.17	0.00e+00	1063.00
IUUC-Cja-018720	Callithrix jacchus	96.78	0.00e+00	1123.00
IUUC-Cfa-020805	Canis familiaris	93.39	0.00e+00	1078.00
IUUC-Cpo-021808	Cavia porcellus	89.64	0.00e+00	1045.00
IUUC-Cre-022877	Chlamydomonas reinhardtii	31.49	1.00e-18	85.90
IUUC-Cho-024783	Choloepus hoffmanni	67.21	0.00e+00	634.00
IUUC-Cgl-026530	Colletotrichum gloeosporioides	25.21	1.00e-14	75.90
IUUC-Dno-028882	Dasypus novemcinctus	93.21	0.00e+00	1087.00
IUUC-Dor-030693	Dipodomys ordii	70.46	0.00e+00	729.00
IUUC-Ete-032724	Echinops telfairi	77.29	0.00e+00	870.00
IUUC-Eca-034052	Equus caballus	92.70	0.00e+00	1076.00
IUUC-Eeu-034465	Erinaceus europaeus	89.69	0.00e+00	949.00
IUUC-Fca-036319	Felis catus	93.39	0.00e+00	1085.00
IUUC-Fal-037347	Ficedula albicollis	56.35	2.00e-86	311.00
IUUC-Gga-041045	Gallus gallus	62.96	2.00e-99	355.00
IUUC-Gma-043405	Glycine max	37.41	2.00e-36	146.00
IUUC-Ggo-044694	Gorilla gorilla	90.83	0.00e+00	1024.00
IUUC-Hsa-045920	Homo sapiens	99.15	0.00e+00	1144.00
IUUC-Hvu-047684	Hordeum vulgare	45.22	6.00e-44	171.00
IUUC-Itr-048799	Ictidomys tridecemlineatus	93.38	0.00e+00	1088.00
IUUC-Lch-049790	Latimeria chalumnae	63.25	2.00e-88	318.00
IUUC-Lpe-051248	Leersia perrieri	38.63	2.00e-42	166.00
IUUC-Lma-052978	Leptosphaeria maculans	34.39	2.00e-20	94.40
IUUC-Laf-053368	Loxodonta africana	90.49	0.00e+00	1051.00
IUUC-Mcc-055057	Macaca mulatta	97.96	0.00e+00	1131.00
IUUC-Meu-056435	Macropus eugenii	56.59	0.00e+00	639.00
IUUC-Mtr-058391	Medicago truncatula	37.66	2.00e-36	146.00
IUUC-Mmr-061684	Microcebus murinus	94.74	0.00e+00	1108.00
IUUC-Mdo-062858	Monodelphis domestica	69.79	9.00e-136	476.00
IUUC-Mmu-063498	Mus musculus	85.93	0.00e+00	978.00
IUUC-Mpu-066611	Mustela putorius furo	89.95	0.00e+00	1021.00
IUUC-Mlu-067118	Myotis lucifugus	87.90	0.00e+00	1082.00
IUUC-Ncr-068706	Neurospora crassa	29.91	1.00e-16	82.00
IUUC-Nle-069443	Nomascus leucogenys	98.98	0.00e+00	1143.00
IUUC-Opr-070806	Ochotona princeps	80.54	0.00e+00	911.00
IUUC-Oan-073590	Ornithorhynchus anatinus	55.12	1.00e-79	289.00
IUUC-Ocu-073901	Oryctolagus cuniculus	91.53	0.00e+00	1079.00
IUUC-Oga-089135	Otolemur garnettii	95.08	0.00e+00	1102.00
IUUC-Oar-089942	Ovis aries	91.51	0.00e+00	1072.00
IUUC-Pan-092887	Papio anubis	97.15	0.00e+00	923.00
IUUC-Psi-093140	Pelodiscus sinensis	51.48	2.00e-142	499.00
IUUC-Pno-094805	Phaeosphaeria nodorum	34.81	1.00e-21	98.20
IUUC-Pab-098511	Pongo abelii	98.63	2.00e-162	565.00
IUUC-Pca-100253	Procavia capensis	63.56	0.00e+00	637.00
IUUC-Ppe-101189	Prunus persica	41.08	7.00e-34	137.00
IUUC-Pva-103179	Pteropus vampyrus	90.15	0.00e+00	1039.00
IUUC-Pte-104020	Pyrenophora teres	32.70	5.00e-18	86.70
IUUC-Pyt-104575	Pyrenophora triticirepentis	31.65	7.00e-19	89.40
IUUC-Rno-105258	Rattus norvegicus	86.95	0.00e+00	973.00
IUUC-Sha-107397	Sarcophilus harrisii	39.93	8.00e-100	357.00
IUUC-Sit-110193	Setaria italica	42.48	2.00e-43	169.00
IUUC-Stu-112651	Solanum tuberosum	37.39	5.00e-36	145.00
IUUC-Sar-113372	Sorex araneus	89.83	0.00e+00	915.00
IUUC-Sbi-114067	Sorghum bicolor	42.29	2.00e-43	170.00
IUUC-Ssc-115700	Sus scrofa	90.03	0.00e+00	1025.00
IUUC-Tgu-117433	Taeniopygia guttata	61.67	5.00e-86	310.00
IUUC-Tsy-118960	Tarsius syrichta	83.40	0.00e+00	833.00
IUUC-Tca-121652	Theobroma cacao	40.17	2.00e-37	150.00
IUUC-Tae-125765	Triticum aestivum	43.29	4.00e-44	172.00
IUUC-Tur-126817	Triticum urartu	43.72	4.00e-44	172.00
IUUC-Tbe-127893	Tupaia belangeri	66.43	0.00e+00	663.00
IUUC-Ttr-128910	Tursiops truncatus	92.61	0.00e+00	995.00
IUUC-Vda-129779	Verticillium dahliae	24.08	1.00e-10	62.00
IUUC-Vpa-130290	Vicugna pacos	93.21	0.00e+00	1095.00
IUUC-Vvi-131660	Vitis vinifera	40.09	2.00e-37	149.00
IUUC-Zma-135913	Zea mays	41.41	2.00e-42	167.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence