iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-051899

Ensembl Protein ID

ENSLOCP00000015394.1

UniProt Accession

W5N435; W5N435_LEPOC

Genbank Protein ID

ENSLOCP00000015394

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01026404

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000012494.1	ENSLOCT00000015423.1	ENSLOCP00000015394.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.80e-195	649.5	429	918

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv......gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealke 83
           YD +++++Ge+ ++kl + + +lvG+g++GcE+lKn++l+G       g++ ++D d +e+snlnrqFLfr+++++ +K+ +aa a  +
   Q: 429  YDALRACIGETMCQKLHRLRTFLVGCGAIGCEMLKNFALLGAgvasssGELFITDPDLIEKSNLNRQFLFRPHHIQYPKSSTAATATLD 517
           9**************************************99888********************************************* PP
   S: 84   lnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqk 169
           +np+ ++ ah +++++ +e+i+   F++++dvVv+aldn+earr+v+++cl++r+pl++sgt+G++G+++vi++ +te+y++++dpp++
   Q: 518  INPQLKINAHLNKVCPATESIYsdeFYNRIDVVVTALDNVEARRYVDSRCLSNRKPLLDSGTMGTKGHTEVIVPDMTESYNSHRDPPEE 606
           ***************************************************************************************** PP
   S: 170  tiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafa 246
           ++Pfctlk++p+++ehti+wa            ++ nk+++++++ eevl++++s+e+++g ++v  +l s+++ +++ ++++a+ +f+
   Q: 607  EVPFCTLKSFPAVIEHTIQWArdkfesafthkpSIYNKFWQTYSSVEEVLQRMKSQETLDGSFQV-IKLLSRRPMSWASCVTLARLKFE 694
           *****************************************************************.999******************** PP
   S: 247  kttinsikqllksfecdivtkskspfwv.........................................................sfcs 278
           k+++ ++ qll+sf+ d   k++s fw+                                                         ++++
   Q: 695  KYFKRKAVQLLHSFPLDTKLKDGSLFWQspkrppspidfdfkdplhfsfivsaarlfaemyniphaekdlspetiiriisgvtipEYKP 783
           *************************************************************************************8888 PP
   S: 279  naealqvpekvekdeevvkasap.......lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddli 358
            +++++++e++ k+e+++ + ++       ++l+  + + + +k+ +  + + fekddds  ++d++taa+nlra +++iep +d+ ++
   Q: 784  AEKKIEIDENARKPEQTKLVVSSeeeqeaiSQLEDVISSHAVTKDHLHIKPVFFEKDDDSngHIDFITAASNLRARMYNIEP-ADRLKT 871
           888888777766666544332222346663344444445566777788889*******************************.****** PP
   S: 359  keiagniipaiattnavvgGlaaqEviKvvsg.kfeplknfflfdae 404
           k+iag+iipaiat +a+v+Gl+a+E+iK+v g +f+ +kn+f+++a+
   Q: 872  KRIAGKIIPAIATATAAVSGLVALEIIKIVGGhCFDSFKNCFFNLAI 918
           ********************************99*********9876 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MSVALHTDRK FEEHIPRMAA DSMEIDDSLY SRQRYVLGDS AMQQMAQSHV FLSGMGGLGV 60
EMAKNIVLAG VKALTVHDAK KCEIWDLGTN FFIHEEDVLS NKARVEAVYP RIAELNPYVQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCTATTAG CTGTTGGTCT TTACAATAGT TTCCAGCCAC TTTTGGAAGG ACACATTTTT 60
GTTTGGTCAG GAATGAGACT TTTCCCTGCC CAGCACTGCA CAGCTCTGTG TCAATTTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001608	Ailuropoda melanoleuca	68.76	0.00e+00	1502.00
IUUC-Apl-004158	Anas platyrhynchos	72.40	0.00e+00	1538.00
IUUC-Aca-005349	Anolis carolinensis	71.33	0.00e+00	1561.00
IUUC-Bta-012696	Bos taurus	68.66	0.00e+00	1493.00
IUUC-Cja-019563	Callithrix jacchus	68.13	0.00e+00	1482.00
IUUC-Cfa-020951	Canis familiaris	69.35	0.00e+00	1514.00
IUUC-Cpo-022307	Cavia porcellus	66.80	0.00e+00	1459.00
IUUC-Csa-023647	Chlorocebus sabaeus	68.33	0.00e+00	1495.00
IUUC-Cho-024682	Choloepus hoffmanni	56.22	0.00e+00	699.00
IUUC-Dre-028022	Danio rerio	73.82	0.00e+00	1618.00
IUUC-Dno-029796	Dasypus novemcinctus	68.59	0.00e+00	1486.00
IUUC-Dor-030981	Dipodomys ordii	57.81	0.00e+00	1168.00
IUUC-Ete-032514	Echinops telfairi	59.95	0.00e+00	864.00
IUUC-Eca-033697	Equus caballus	68.88	0.00e+00	1501.00
IUUC-Eeu-035323	Erinaceus europaeus	65.19	0.00e+00	1044.00
IUUC-Fca-035858	Felis catus	69.18	0.00e+00	1513.00
IUUC-Fal-036848	Ficedula albicollis	71.62	0.00e+00	1543.00
IUUC-Gmo-039326	Gadus morhua	72.98	0.00e+00	1530.00
IUUC-Gga-040747	Gallus gallus	71.72	0.00e+00	1529.00
IUUC-Gac-041406	Gasterosteus aculeatus	73.95	0.00e+00	1537.00
IUUC-Ggo-044577	Gorilla gorilla	68.16	0.00e+00	1488.00
IUUC-Hsa-046007	Homo sapiens	68.33	0.00e+00	1485.00
IUUC-Itr-048191	Ictidomys tridecemlineatus	73.40	0.00e+00	815.00
IUUC-Lch-049992	Latimeria chalumnae	70.45	0.00e+00	1488.00
IUUC-Laf-054413	Loxodonta africana	67.66	0.00e+00	1392.00
IUUC-Mcc-054656	Macaca mulatta	68.23	0.00e+00	1490.00
IUUC-Meu-056463	Macropus eugenii	58.92	0.00e+00	1130.00
IUUC-Mga-059721	Meleagris gallopavo	70.54	0.00e+00	1430.00
IUUC-Mmr-060908	Microcebus murinus	66.47	0.00e+00	1436.00
IUUC-Mdo-062096	Monodelphis domestica	70.49	0.00e+00	1531.00
IUUC-Mmu-064114	Mus musculus	69.40	0.00e+00	1516.00
IUUC-Mpu-066017	Mustela putorius furo	68.79	0.00e+00	1506.00
IUUC-Mlu-068037	Myotis lucifugus	67.80	0.00e+00	1471.00
IUUC-Nle-069494	Nomascus leucogenys	68.33	0.00e+00	1486.00
IUUC-Ont-071592	Oreochromis niloticus	75.12	0.00e+00	1589.00
IUUC-Oan-073268	Ornithorhynchus anatinus	67.11	0.00e+00	1339.00
IUUC-Ocu-074296	Oryctolagus cuniculus	69.35	0.00e+00	1505.00
IUUC-Ola-086376	Oryzias latipes	73.75	0.00e+00	1520.00
IUUC-Oga-088186	Otolemur garnettii	68.59	0.00e+00	1479.00
IUUC-Oar-089307	Ovis aries	68.66	0.00e+00	1496.00
IUUC-Ptr-090609	Pan troglodytes	68.23	0.00e+00	1484.00
IUUC-Pan-092905	Papio anubis	67.61	0.00e+00	1417.00
IUUC-Psi-093489	Pelodiscus sinensis	71.72	0.00e+00	1545.00
IUUC-Pma-094203	Petromyzon marinus	64.58	4.00e-56	209.00
IUUC-Pfo-096670	Poecilia formosa	74.63	0.00e+00	1600.00
IUUC-Pab-098418	Pongo abelii	68.00	0.00e+00	1478.00
IUUC-Pca-100889	Procavia capensis	57.53	0.00e+00	1184.00
IUUC-Pva-103144	Pteropus vampyrus	61.30	0.00e+00	1059.00
IUUC-Rno-105612	Rattus norvegicus	69.50	0.00e+00	1519.00
IUUC-Sha-107388	Sarcophilus harrisii	70.56	0.00e+00	1518.00
IUUC-Sar-113128	Sorex araneus	68.69	0.00e+00	1491.00
IUUC-Ssc-116117	Sus scrofa	68.13	0.00e+00	1492.00
IUUC-Tgu-116565	Taeniopygia guttata	71.92	0.00e+00	1548.00
IUUC-Tru-118591	Takifugu rubripes	73.26	0.00e+00	1558.00
IUUC-Tsy-119436	Tarsius syrichta	60.66	0.00e+00	1246.00
IUUC-Tni-120880	Tetraodon nigroviridis	73.12	0.00e+00	1544.00
IUUC-Tbe-127714	Tupaia belangeri	60.90	0.00e+00	1070.00
IUUC-Ttr-129159	Tursiops truncatus	65.32	0.00e+00	1220.00
IUUC-Vpa-130716	Vicugna pacos	66.14	0.00e+00	1405.00
IUUC-Xtr-132947	Xenopus tropicalis	64.49	0.00e+00	1392.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence