iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027814

UUCD1 version

UUC-DaR-01352

Ensembl Protein ID

ENSDARP00000003705.5

UniProt Accession

Q803J2; Q803J2_DANRE

Genbank Protein ID

AAH44461.1; AAI64904.1; CAK04885.1

Protein Name

Ube2n protein; Ubiquitin-conjugating enzyme E2N; Ubiquitin-conjugating enzyme E2Na

Genbank Nucleotide ID

CR753897; BC164904; BX572633

Gene Name

ube2na; ube2n; CH211-276P10.3-001

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000008748.7	ENSDART00000014188.6	ENSDARP00000003705.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	6.10e-47	159.8	7	139

Active Site

Position(s)	Description	Evidence
87	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R+ ke+++l ++p++gi+a+p++  +   ++v+i Gp+d+p+egg+Fkle+ +pe+YP+ +Pkv+f+tki+hPnv++ G++Cl+ilk  
   Q: 7    RIIKETQRLLAEPVPGIKAEPDEG-NARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILK-- 92
           899********************9.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkk 136
           +kWspal++++vllsiq+ll+ pnp++pl +++ae++k+n+++  ++
   Q: 93   DKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIET 139
           ****************************************9876555 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MAGLPRRIIK ETQRLLAEPV PGIKAEPDEG NARYFHVVIA GPQDSPFEGG TFKLELFLPE 60
EYPMAAPKVR FMTKIYHPNV DKLGRICLDI LKDKWSPALQ IRTVLLSIQA LLSAPNPDDP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGCACCGCG CCGGAAGGCG TGTGTCTGTG CACTGCGTCT CCGCCGTCAA TGCAAACGAA 60
GTAAGAGGCA CCGTGAGTCA AAGCTAAAAT CCGCATTCAA GACAAGATGG CAGGGTTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0042769--P:DNA damage response, detection of DNA damage
GO:0006301--P:postreplication repair
GO:0070534--P:protein K63-linked ubiquitination
GO:0000209--P:protein polyubiquitination

KEGG

dre:406807

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000100	Aegilops tauschii	78.52	4.00e-69	253.00
IUUC-Aml-001889	Ailuropoda melanoleuca	95.86	6.00e-80	289.00
IUUC-Apl-003469	Anas platyrhynchos	95.89	3.00e-81	293.00
IUUC-Aca-005051	Anolis carolinensis	98.03	1.00e-85	308.00
IUUC-Afl-008733	Aspergillus flavus	72.60	5.00e-63	233.00
IUUC-Ani-009482	Aspergillus nidulans	71.62	4.00e-63	233.00
IUUC-Ang-009678	Aspergillus niger	72.60	9.00e-63	232.00
IUUC-Aor-010025	Aspergillus oryzae	72.60	5.00e-63	233.00
IUUC-Ame-010742	Astyanax mexicanus	100.00	1.00e-88	318.00
IUUC-Bgr-012156	Blumeria graminis	65.33	2.00e-53	201.00
IUUC-Bta-012636	Bos taurus	98.03	1.00e-85	308.00
IUUC-Bci-013761	Botrytis cinerea	72.30	3.00e-62	230.00
IUUC-Cel-018119	Caenorhabditis elegans	87.92	2.00e-74	271.00
IUUC-Cja-019108	Callithrix jacchus	98.03	1.00e-85	308.00
IUUC-Cfa-020561	Canis familiaris	97.37	7.00e-85	305.00
IUUC-Cpo-022280	Cavia porcellus	94.70	1.00e-81	294.00
IUUC-Cre-022978	Chlamydomonas reinhardtii	78.91	6.00e-67	246.00
IUUC-Csa-023860	Chlorocebus sabaeus	90.79	2.00e-78	284.00
IUUC-Cho-024459	Choloepus hoffmanni	98.03	1.00e-85	308.00
IUUC-Cin-025278	Ciona intestinalis	80.14	5.00e-68	249.00
IUUC-Cgl-026752	Colletotrichum gloeosporioides	71.92	5.00e-61	226.00
IUUC-Cme-027100	Cyanidioschyzon merolae	65.77	3.00e-56	210.00
IUUC-Dno-030059	Dasypus novemcinctus	96.05	1.00e-83	301.00
IUUC-Dor-030269	Dipodomys ordii	99.22	1.00e-72	264.00
IUUC-Ete-032369	Echinops telfairi	98.03	1.00e-85	308.00
IUUC-Eca-033230	Equus caballus	98.03	1.00e-85	308.00
IUUC-Fca-036161	Felis catus	93.42	2.00e-81	293.00
IUUC-Fal-036781	Ficedula albicollis	94.74	9.00e-83	298.00
IUUC-Gmo-039561	Gadus morhua	92.86	3.00e-83	300.00
IUUC-Ggr-039807	Gaeumannomyces graminis	73.29	3.00e-62	230.00
IUUC-Gga-041024	Gallus gallus	98.03	1.00e-85	308.00
IUUC-Ggo-044660	Gorilla gorilla	97.37	7.00e-85	305.00
IUUC-Hsa-045881	Homo sapiens	98.03	1.00e-85	308.00
IUUC-Itr-048350	Ictidomys tridecemlineatus	88.96	3.00e-77	280.00
IUUC-Lpe-051394	Leersia perrieri	79.73	5.00e-70	256.00
IUUC-Loc-052205	Lepisosteus oculatus	100.00	8.00e-89	318.00
IUUC-Lma-053056	Leptosphaeria maculans	72.60	3.00e-62	230.00
IUUC-Laf-053540	Loxodonta africana	97.89	1.00e-79	288.00
IUUC-Mcc-054863	Macaca mulatta	98.03	1.00e-85	308.00
IUUC-Meu-056482	Macropus eugenii	97.89	1.00e-79	288.00
IUUC-Mor-057014	Magnaporthe oryzae	72.60	5.00e-61	226.00
IUUC-Mla-058920	Melampsora laricipopulina	70.07	6.00e-61	226.00
IUUC-Mga-059649	Meleagris gallopavo	94.63	1.00e-80	291.00
IUUC-Mvi-060483	Microbotryum violaceum	75.00	6.00e-65	239.00
IUUC-Mmr-061167	Microcebus murinus	98.03	1.00e-85	308.00
IUUC-Mdo-062701	Monodelphis domestica	98.03	1.00e-85	308.00
IUUC-Mmu-064070	Mus musculus	98.03	1.00e-85	308.00
IUUC-Mac-064742	Musa acuminata	80.41	7.00e-71	259.00
IUUC-Mpu-066401	Mustela putorius furo	98.03	2.00e-85	307.00
IUUC-Mlu-067229	Myotis lucifugus	96.60	7.00e-81	292.00
IUUC-Ncr-068643	Neurospora crassa	72.60	1.00e-61	228.00
IUUC-Nle-070146	Nomascus leucogenys	98.03	1.00e-85	308.00
IUUC-Opr-070232	Ochotona princeps	76.97	5.00e-62	229.00
IUUC-Ont-072369	Oreochromis niloticus	94.81	3.00e-84	303.00
IUUC-Oan-073174	Ornithorhynchus anatinus	94.08	1.00e-81	294.00
IUUC-Ocu-074712	Oryctolagus cuniculus	98.03	1.00e-85	308.00
IUUC-Oba-075408	Oryza barthii	79.73	5.00e-70	256.00
IUUC-Obr-076881	Oryza brachyantha	79.73	5.00e-70	256.00
IUUC-Ogl-077242	Oryza glaberrima	79.73	5.00e-70	256.00
IUUC-Ogu-078465	Oryza glumaepatula	79.73	5.00e-70	256.00
IUUC-Oin-080035	Oryza indica	79.86	7.00e-66	242.00
IUUC-Olo-080555	Oryza longistaminata	79.73	5.00e-70	256.00
IUUC-Ome-081653	Oryza meridionalis	79.73	5.00e-70	256.00
IUUC-Oni-082400	Oryza nivara	79.73	5.00e-70	256.00
IUUC-Opu-083130	Oryza punctata	80.43	3.00e-65	241.00
IUUC-Oru-084649	Oryza rufipogon	79.73	5.00e-70	256.00
IUUC-Osa-085629	Oryza sativa	79.73	5.00e-70	256.00
IUUC-Olu-087886	Ostreococcus lucimarinus	68.03	4.00e-58	216.00
IUUC-Oga-088983	Otolemur garnettii	94.00	5.00e-81	292.00
IUUC-Oar-090440	Ovis aries	97.37	6.00e-85	305.00
IUUC-Ptr-090572	Pan troglodytes	98.03	1.00e-85	308.00
IUUC-Pan-092503	Papio anubis	96.05	8.00e-84	301.00
IUUC-Psi-093419	Pelodiscus sinensis	97.79	3.00e-76	276.00
IUUC-Pma-094136	Petromyzon marinus	91.67	2.00e-42	163.00
IUUC-Pno-094838	Phaeosphaeria nodorum	72.30	4.00e-63	233.00
IUUC-Ppa-096014	Physcomitrella patens	81.63	1.00e-70	258.00
IUUC-Pab-097778	Pongo abelii	98.03	1.00e-85	308.00
IUUC-Pop-099707	Populus trichocarpa	79.73	3.00e-70	256.00
IUUC-Pca-100334	Procavia capensis	82.24	2.00e-71	260.00
IUUC-Pva-102979	Pteropus vampyrus	98.03	1.00e-85	308.00
IUUC-Pte-104137	Pyrenophora teres	71.23	2.00e-61	227.00
IUUC-Pyt-104513	Pyrenophora triticirepentis	71.23	2.00e-61	227.00
IUUC-Sha-107493	Sarcophilus harrisii	98.03	1.00e-85	308.00
IUUC-Spo-108062	Schizosaccharomyces pombe	69.18	2.00e-56	211.00
IUUC-Ssl-108395	Sclerotinia sclerotiorum	71.23	2.00e-60	224.00
IUUC-Smo-109587	Selaginella moellendorffii	74.67	1.00e-63	235.00
IUUC-Sar-113464	Sorex araneus	97.89	1.00e-79	288.00
IUUC-Sre-114927	Sporisorium reilianum	78.08	1.00e-66	245.00
IUUC-Ssc-116096	Sus scrofa	98.03	1.00e-85	308.00
IUUC-Tgu-117266	Taeniopygia guttata	97.89	1.00e-79	288.00
IUUC-Tsy-118952	Tarsius syrichta	97.89	1.00e-79	288.00
IUUC-Tca-121752	Theobroma cacao	73.08	1.00e-65	243.00
IUUC-Tre-121979	Trichoderma reesei	73.97	5.00e-62	229.00
IUUC-Tvi-122515	Trichoderma virens	73.29	2.00e-61	227.00
IUUC-Tbe-127846	Tupaia belangeri	97.89	1.00e-79	288.00
IUUC-Vda-129810	Verticillium dahliae	71.23	2.00e-60	224.00
IUUC-Vpa-130221	Vicugna pacos	90.65	1.00e-68	251.00
IUUC-Xtr-132366	Xenopus tropicalis	95.45	7.00e-83	298.00
IUUC-Yli-134605	Yarrowia lipolytica	72.97	2.00e-63	234.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence