iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090401

Ensembl Protein ID

ENSOARP00000008842.1

UniProt Accession

W5PEH8; W5PEH8_SHEEP

Genbank Protein ID

ENSOARP00000008842

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01087809

Gene Name

NOD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000008243.1	ENSOART00000008970.1	ENSOARP00000008842.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/CARD	80.92	0.00e+00	1503.00	IUUC-Hsa-046886

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

VWGKQPLASL TMEKHGRSEM EIVPSEPHSF IKLLKVSREH LVTHIRNTQC LLDNLLQNDY 60
FSTEDAEIVC ACPTQPDKVR RILDLVQSKG EEVSEFFLHV IQQLSDAYVD LKPWLSEIGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTGGGGAA AGCAGCCGCT TGCGTCTTTA ACCATGGAAA AGCACGGCCG CAGTGAGATG 60
GAAATAGTCC CATCAGAGCC TCACTCCTTC ATCAAGTTGT TGAAAGTCAG CCGGGAGCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001611--Leu-rich_rpt
IPR007111--NACHT_NTPase

PROSITE

PS50209--CARD
PS50837--NACHT

Pfam

PF00619--CARD
PF13516--LRR_6

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0071225--P:cellular response to muramyl dipeptide
GO:0050830--P:defense response to Gram-positive bacterium
GO:0016045--P:detection of bacterium
GO:0042228--P:interleukin-8 biosynthetic process
GO:0035556--P:intracellular signal transduction
GO:0002606--P:positive regulation of dendritic cell antigen processing and presentation
GO:0070374--P:positive regulation of ERK1 and ERK2 cascade
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032755--P:positive regulation of interleukin-6 production
GO:0046330--P:positive regulation of JNK cascade
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0032760--P:positive regulation of tumor necrosis factor production
GO:1904417--P:positive regulation of xenophagy

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001299	Ailuropoda melanoleuca	80.92	0.00e+00	1366.00
IUUC-Apl-003908	Anas platyrhynchos	63.02	0.00e+00	1164.00
IUUC-Aca-005144	Anolis carolinensis	61.69	0.00e+00	1145.00
IUUC-Ame-010829	Astyanax mexicanus	50.05	0.00e+00	865.00
IUUC-Bta-013358	Bos taurus	95.28	0.00e+00	1694.00
IUUC-Cja-019392	Callithrix jacchus	80.61	0.00e+00	1431.00
IUUC-Cfa-020776	Canis familiaris	82.38	0.00e+00	1464.00
IUUC-Cpo-021393	Cavia porcellus	75.92	0.00e+00	1342.00
IUUC-Csa-023872	Chlorocebus sabaeus	80.92	0.00e+00	1479.00
IUUC-Cho-024569	Choloepus hoffmanni	69.54	6.00e-165	574.00
IUUC-Dre-027478	Danio rerio	49.52	0.00e+00	840.00
IUUC-Dno-029231	Dasypus novemcinctus	81.76	0.00e+00	1488.00
IUUC-Dor-030251	Dipodomys ordii	56.38	1.00e-155	543.00
IUUC-Ete-032484	Echinops telfairi	69.59	0.00e+00	703.00
IUUC-Eca-033564	Equus caballus	84.87	0.00e+00	1531.00
IUUC-Eeu-034456	Erinaceus europaeus	62.32	1.00e-128	453.00
IUUC-Fca-036372	Felis catus	82.49	0.00e+00	1460.00
IUUC-Fal-037418	Ficedula albicollis	62.92	0.00e+00	1164.00
IUUC-Gmo-038740	Gadus morhua	50.27	0.00e+00	866.00
IUUC-Gga-040775	Gallus gallus	62.95	0.00e+00	1194.00
IUUC-Gac-041612	Gasterosteus aculeatus	49.53	0.00e+00	865.00
IUUC-Ggo-045161	Gorilla gorilla	79.73	0.00e+00	1232.00
IUUC-Hsa-046886	Homo sapiens	80.92	0.00e+00	1478.00
IUUC-Itr-048414	Ictidomys tridecemlineatus	79.79	0.00e+00	1472.00
IUUC-Lch-049764	Latimeria chalumnae	59.07	0.00e+00	973.00
IUUC-Loc-052143	Lepisosteus oculatus	54.03	0.00e+00	960.00
IUUC-Laf-053503	Loxodonta africana	78.51	0.00e+00	1451.00
IUUC-Mcc-054992	Macaca mulatta	80.92	0.00e+00	1476.00
IUUC-Meu-056406	Macropus eugenii	60.22	0.00e+00	1068.00
IUUC-Mga-059351	Meleagris gallopavo	62.29	0.00e+00	1186.00
IUUC-Mmr-061537	Microcebus murinus	80.92	0.00e+00	1401.00
IUUC-Mdo-061832	Monodelphis domestica	63.82	0.00e+00	1052.00
IUUC-Mmu-064282	Mus musculus	76.80	0.00e+00	1375.00
IUUC-Mpu-066399	Mustela putorius furo	82.70	0.00e+00	1474.00
IUUC-Mlu-067265	Myotis lucifugus	80.48	0.00e+00	1421.00
IUUC-Nle-069078	Nomascus leucogenys	80.71	0.00e+00	1475.00
IUUC-Opr-070946	Ochotona princeps	71.01	0.00e+00	1258.00
IUUC-Ont-071355	Oreochromis niloticus	49.09	0.00e+00	863.00
IUUC-Oan-072937	Ornithorhynchus anatinus	72.97	0.00e+00	1342.00
IUUC-Ocu-073815	Oryctolagus cuniculus	78.30	0.00e+00	1455.00
IUUC-Ola-087381	Oryzias latipes	49.14	0.00e+00	856.00
IUUC-Oga-088725	Otolemur garnettii	79.77	0.00e+00	1456.00
IUUC-Ptr-090590	Pan troglodytes	80.82	0.00e+00	1473.00
IUUC-Pan-091765	Papio anubis	80.71	0.00e+00	1474.00
IUUC-Psi-093182	Pelodiscus sinensis	63.31	0.00e+00	1141.00
IUUC-Ppa-095344	Physcomitrella patens	30.11	5.00e-04	40.00
IUUC-Pfo-097422	Poecilia formosa	47.87	0.00e+00	845.00
IUUC-Pab-098289	Pongo abelii	80.82	0.00e+00	1472.00
IUUC-Pca-100165	Procavia capensis	72.33	0.00e+00	951.00
IUUC-Pva-102943	Pteropus vampyrus	83.33	0.00e+00	1489.00
IUUC-Rno-104930	Rattus norvegicus	76.62	0.00e+00	1385.00
IUUC-Sha-106800	Sarcophilus harrisii	57.60	6.00e-176	611.00
IUUC-Sar-113205	Sorex araneus	71.03	0.00e+00	969.00
IUUC-Ssc-115910	Sus scrofa	86.64	0.00e+00	1369.00
IUUC-Tgu-117179	Taeniopygia guttata	63.48	0.00e+00	1169.00
IUUC-Tru-118220	Takifugu rubripes	47.92	0.00e+00	823.00
IUUC-Tsy-119418	Tarsius syrichta	77.78	0.00e+00	1139.00
IUUC-Tni-120033	Tetraodon nigroviridis	50.18	2.00e-66	245.00
IUUC-Tbe-127308	Tupaia belangeri	91.01	0.00e+00	667.00
IUUC-Ttr-129233	Tursiops truncatus	87.11	0.00e+00	1578.00
IUUC-Vpa-130620	Vicugna pacos	85.26	5.00e-117	415.00
IUUC-Xtr-132075	Xenopus tropicalis	54.81	0.00e+00	997.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence