iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035611

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02078436

Gene Name

BAP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000015711.2	ENSFCAT00000015715.2	ENSFCAP00000014571.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.60e-164	547.4	8	729

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 11   LesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsC 99
           L   Pglftllvedfgvk++ qvee+y+L++++    q+pv+g+++lFk++e+r+s+rk++++++d++v+d+di++++ffa+q+i+NsC
   Q: 8    LSPHPGLFTLLVEDFGVKGV-QVEEIYDLQSKC----QGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSC 91
           6668****************.************....**************************************************** PP
   S: 100  atyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvning 188
           at+Allsvllnc+++  dlG+tlsr+k++tk++spe+k++a+gn+++l+++hns+ar+e+r++pe+q+++++++t+eafhfvsyv+i+g
   Q: 92   ATHALLSVLLNCSNV--DLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITG 178
           *************99..************************************************************************ PP
   S: 189  rlyeldglkpfPldlgkkketeelkdklkvvraflerikllesde....irfnllaivadrrviktlrlnvlkid.............. 259
           rl+eldglk++P+d+g+++e+ee++dk+++v+  +eri+l++++e    irfnl+a+v+drr+++++rl+vlk++              
   Q: 179  RLFELDGLKVYPIDHGPWGEDEEWTDKARRVI--MERIGLATAGEpyhdIRFNLMAVVPDRRIKYEARLHVLKVNrqtvlealqqlirv 265
           ********************************..******************************************************* PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 266  tqpeliqthksqepqlpeeskpassksplaleagrapaasegihtdgvedvagscpqapshsppskpklvvkppgsslngvppnptpiv 354
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 355  qrlpafldnhnyakspmqeeedlaagvgrsrapvrppqqysddeddyeddedddvqntnsairykrkgpgkpgplsgsgdgqlsvlqpn 443
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 444  tinvlaeklkesqkdlsiplsiktssgaaspavavpthpqpsptpsnestdtaseigsafnsplrspirsanptrpsspvtshiskvlf 532
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 533  geddsllrvdcirynravrdlgpvistgllhlaedgvlsplaltecgkgsspcsrpsqgsqgssspeekevvesadgrekpglarpgep 621
           ***************************************************************************************** PP
   S: 260  ........keLlkLlkdieseeekieaqlddekekrkkfkiddirRtenydeficifikdlaregilrklveetisevrefgvnegrla 340
                   keLl+Llk++e+e++++ea+l++e+ekrkkfkidd+rRt+nydefic+fi++la+eg+l++lve++is++r++gv++grl+
   Q: 622  lsgekyspKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLH 710
           ***************************************************************************************** PP
   S: 341  kqrkqgrekkirplkrkrk 359
           kqrk++r+k++rp+k+kr+
   Q: 711  KQRKPDRRKRSRPYKAKRQ 729
           *****************97 PP

Organism

Felis catus

Protein Sequence
(Fasta)

LTTSPLLLSP HPGLFTLLVE DFGVKGVQVE EIYDLQSKCQ GPVYGFIFLF KWIEERRSRR 60
KVSTLVDDTS VIDDDIVNNM FFAHQLIPNS CATHALLSVL LNCSNVDLGP TLSRMKDFTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTGACCACC AGCCCGCTCC TCTTGTCGCC CCACCCAGGC CTCTTCACCC TCCTGGTGGA 60
AGATTTCGGT AAGAGCCTCT CCTACCCGTC GGATCCGGCT TTTGGCGGGG GGGGGGGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001578--Peptidase_C12_UCH

Pfam

PF01088--Peptidase_C12

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0035517--C:PR-DUB complex
GO:0003682--F:chromatin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0061519--P:macrophage homeostasis
GO:0035522--P:monoubiquitinated histone H2A deubiquitination
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0016579--P:protein deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0051726--P:regulation of cell cycle
GO:0001558--P:regulation of cell growth
GO:1900015--P:regulation of cytokine production involved in inflammatory response
GO:0010035--P:response to inorganic substance
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001263	Ailuropoda melanoleuca	95.35	0.00e+00	1198.00
IUUC-Apl-003405	Anas platyrhynchos	69.42	0.00e+00	630.00
IUUC-Aca-004836	Anolis carolinensis	79.32	0.00e+00	1146.00
IUUC-Ame-011946	Astyanax mexicanus	61.56	0.00e+00	853.00
IUUC-Bta-013131	Bos taurus	91.48	0.00e+00	1051.00
IUUC-Cja-019599	Callithrix jacchus	95.03	0.00e+00	1279.00
IUUC-Cfa-021003	Canis familiaris	97.65	0.00e+00	1199.00
IUUC-Cpo-022143	Cavia porcellus	94.48	0.00e+00	1258.00
IUUC-Csa-023477	Chlorocebus sabaeus	95.17	0.00e+00	1253.00
IUUC-Cho-024734	Choloepus hoffmanni	82.42	0.00e+00	738.00
IUUC-Csv-025842	Ciona savignyi	56.60	2.00e-89	322.00
IUUC-Dre-027793	Danio rerio	64.22	0.00e+00	879.00
IUUC-Dno-029253	Dasypus novemcinctus	95.43	0.00e+00	1274.00
IUUC-Dor-030891	Dipodomys ordii	87.43	0.00e+00	1156.00
IUUC-Dme-031796	Drosophila melanogaster	56.99	6.00e-88	317.00
IUUC-Ete-032646	Echinops telfairi	85.71	2.00e-167	582.00
IUUC-Eca-033805	Equus caballus	95.58	0.00e+00	1246.00
IUUC-Eeu-035216	Erinaceus europaeus	93.54	4.00e-144	504.00
IUUC-Fal-037186	Ficedula albicollis	79.42	0.00e+00	989.00
IUUC-Gmo-038824	Gadus morhua	69.59	8.00e-174	603.00
IUUC-Gga-040875	Gallus gallus	80.69	0.00e+00	1086.00
IUUC-Gac-042226	Gasterosteus aculeatus	66.94	0.00e+00	908.00
IUUC-Ggo-045122	Gorilla gorilla	94.89	0.00e+00	1286.00
IUUC-Hsa-045882	Homo sapiens	94.89	0.00e+00	1285.00
IUUC-Itr-048185	Ictidomys tridecemlineatus	96.13	0.00e+00	1272.00
IUUC-Lch-049960	Latimeria chalumnae	71.49	0.00e+00	979.00
IUUC-Loc-052408	Lepisosteus oculatus	74.62	0.00e+00	637.00
IUUC-Laf-054187	Loxodonta africana	95.30	0.00e+00	1229.00
IUUC-Mcc-055273	Macaca mulatta	95.90	0.00e+00	1251.00
IUUC-Meu-056267	Macropus eugenii	83.57	0.00e+00	1135.00
IUUC-Mga-059958	Meleagris gallopavo	93.59	1.00e-153	535.00
IUUC-Mmr-061280	Microcebus murinus	94.76	0.00e+00	1232.00
IUUC-Mdo-062625	Monodelphis domestica	88.95	0.00e+00	1248.00
IUUC-Mmu-063853	Mus musculus	92.68	0.00e+00	1251.00
IUUC-Mlu-067771	Myotis lucifugus	95.17	0.00e+00	1223.00
IUUC-Opr-070741	Ochotona princeps	92.68	0.00e+00	1259.00
IUUC-Ont-072172	Oreochromis niloticus	66.67	0.00e+00	915.00
IUUC-Oan-073167	Ornithorhynchus anatinus	79.14	0.00e+00	1113.00
IUUC-Ocu-074176	Oryctolagus cuniculus	95.01	0.00e+00	1214.00
IUUC-Ola-087203	Oryzias latipes	81.82	3.00e-128	451.00
IUUC-Oga-089153	Otolemur garnettii	94.61	0.00e+00	1267.00
IUUC-Oar-090008	Ovis aries	92.40	0.00e+00	1217.00
IUUC-Ptr-091234	Pan troglodytes	95.17	0.00e+00	1290.00
IUUC-Pan-092005	Papio anubis	95.44	0.00e+00	1274.00
IUUC-Psi-093995	Pelodiscus sinensis	84.11	0.00e+00	654.00
IUUC-Pma-094110	Petromyzon marinus	88.19	6.00e-65	241.00
IUUC-Pfo-097418	Poecilia formosa	64.31	0.00e+00	897.00
IUUC-Pab-098267	Pongo abelii	95.03	0.00e+00	1263.00
IUUC-Pca-101084	Procavia capensis	93.09	0.00e+00	1183.00
IUUC-Pva-102292	Pteropus vampyrus	95.49	0.00e+00	890.00
IUUC-Rno-105251	Rattus norvegicus	90.91	0.00e+00	1220.00
IUUC-Sha-107100	Sarcophilus harrisii	88.42	0.00e+00	1263.00
IUUC-Sar-113559	Sorex araneus	86.48	0.00e+00	1075.00
IUUC-Ssc-115688	Sus scrofa	94.89	0.00e+00	1257.00
IUUC-Tgu-117424	Taeniopygia guttata	81.00	0.00e+00	1117.00
IUUC-Tru-118585	Takifugu rubripes	67.16	0.00e+00	906.00
IUUC-Tsy-119299	Tarsius syrichta	84.57	0.00e+00	947.00
IUUC-Tni-120808	Tetraodon nigroviridis	65.43	0.00e+00	893.00
IUUC-Tbe-127705	Tupaia belangeri	94.82	2.00e-176	611.00
IUUC-Ttr-128225	Tursiops truncatus	94.75	0.00e+00	1222.00
IUUC-Vpa-130193	Vicugna pacos	95.31	3.00e-130	458.00
IUUC-Xtr-132449	Xenopus tropicalis	70.43	0.00e+00	935.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence