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Tag Content
iUUCD ID IUUC-Aor-009927
Ensembl Protein ID BAE59472
UniProt Accession Q2UG43; SEC13_ASPOR
Genbank Protein ID BAE59472.1
Protein Name Protein transport protein sec13
Genbank Nucleotide ID AP007157
Gene Name sec13; AO090023000986
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AO090023000986 BAE59472 BAE59472
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.00e-33 113.2 40 72
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sd..tllvsGsdDgtikvWD 29
           gH++ v+c+a+  +   t+l+s+s+Dg++ +W+
   Q: 40   GHEGAVWCIAWahPKfgTILASSSYDGKVLIWR 72
           8***********9555599*************8 PP
   
Organism Aspergillus oryzae
Functional Description
(View)

Functional Description


     Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Sec13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
 Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Sec13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
Protein Sequence
(Fasta)
MHDAGLDYYG RRLATCSSDK TIKIFEIEGE THRLVETLKG HEGAVWCIAW AHPKFGTILA 60
SSSYDGKVLI WREQHQNTTS PVAVNTWTKV FDFSLHTASV NMVSWAPHES GCLLACASSD 120
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Protein Fasta Sequence


>IUUC-Aor-009927|E3,WD_repeat|Aspergillus oryzae
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Nucleotide Sequence
(Fasta)
ATGGTGCGTT TCCCCCTTTC AGTCCATCCC AATACTGTTT GTTTTTTTCC AAACATTGAC 60
GTTCCGACCT GGACTTTTAG GCGGCTGCTC AGATTATCTC CAATTCCGGA CACGATGACA 120
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Nucleotide Fasta Sequence


>IUUC-Aor-009927|E3,WD_repeat|Aspergillus oryzae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0256--Endoplasmic reticulum
KW-0931--ER-Golgi transport
KW-0472--Membrane
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0811--Translocation
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030127--C:COPII vesicle coat
GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0031080--C:nuclear pore outer ring
GO:0035859--C:Seh1-associated complex
GO:0005198--F:structural molecule activity
GO:0090114--P:COPII-coated vesicle budding
GO:0051028--P:mRNA transport
GO:0031081--P:nuclear pore distribution
GO:0043547--P:positive regulation of GTPase activity
GO:1904263--P:positive regulation of TORC1 signaling
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0015031--P:protein transport
GO:0030433--P:ubiquitin-dependent ERAD pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000671 Aegilops tauschii 49.50 8.00e-77 278.00
IUUC-Aml-001832 Ailuropoda melanoleuca 50.33 6.00e-80 288.00
IUUC-Atr-002914 Amborella trichopoda 50.67 9.00e-78 281.00
IUUC-Apl-003992 Anas platyrhynchos 51.17 4.00e-81 292.00
IUUC-Aca-005283 Anolis carolinensis 50.33 2.00e-80 290.00
IUUC-Aly-005654 Arabidopsis lyrata 47.68 3.00e-70 256.00
IUUC-Ath-006816 Arabidopsis thaliana 47.85 8.00e-70 254.00
IUUC-Ago-007827 Ashbya gossypii 55.96 4.00e-93 332.00
IUUC-Acl-008205 Aspergillus clavatus 93.54 5.00e-166 574.00
IUUC-Afl-008748 Aspergillus flavus 99.66 9.00e-175 603.00
IUUC-Afu-008791 Aspergillus fumigatus 95.90 6.00e-169 584.00
IUUC-Ani-009152 Aspergillus nidulans 89.46 4.00e-161 558.00
IUUC-Ang-009765 Aspergillus niger 94.22 2.00e-167 579.00
IUUC-Ate-010248 Aspergillus terreus 94.90 2.00e-168 582.00
IUUC-Ame-011478 Astyanax mexicanus 51.00 1.00e-81 294.00
IUUC-Bgr-012276 Blumeria graminis 69.49 2.00e-122 429.00
IUUC-Bta-012700 Bos taurus 50.33 3.00e-79 286.00
IUUC-Bci-013722 Botrytis cinerea 71.81 5.00e-124 435.00
IUUC-Bdi-014818 Brachypodium distachyon 49.17 2.00e-76 277.00
IUUC-Bol-015779 Brassica oleracea 47.70 2.00e-69 253.00
IUUC-Bra-017934 Brassica rapa 48.03 1.00e-69 254.00
IUUC-Cel-018479 Caenorhabditis elegans 38.85 4.00e-58 216.00
IUUC-Cja-019956 Callithrix jacchus 50.88 1.00e-73 268.00
IUUC-Cfa-020752 Canis familiaris 50.33 1.00e-79 288.00
IUUC-Cpo-021871 Cavia porcellus 51.00 9.00e-81 291.00
IUUC-Cre-022797 Chlamydomonas reinhardtii 47.81 5.00e-74 269.00
IUUC-Csa-023393 Chlorocebus sabaeus 51.00 2.00e-80 290.00
IUUC-Cho-024786 Choloepus hoffmanni 58.00 2.00e-26 110.00
IUUC-Cin-025332 Ciona intestinalis 53.64 5.00e-84 302.00
IUUC-Csv-025926 Ciona savignyi 53.33 2.00e-83 300.00
IUUC-Cgl-026413 Colletotrichum gloeosporioides 70.71 1.00e-116 410.00
IUUC-Cne-027054 Cryptococcus neoformans 52.24 1.00e-76 278.00
IUUC-Cme-027165 Cyanidioschyzon merolae 35.48 5.00e-47 180.00
IUUC-Dre-027782 Danio rerio 51.33 3.00e-81 293.00
IUUC-Dno-029628 Dasypus novemcinctus 50.00 2.00e-79 287.00
IUUC-Dor-030650 Dipodomys ordii 48.92 8.00e-58 215.00
IUUC-Dse-031206 Dothistroma septosporum 67.11 3.00e-116 409.00
IUUC-Dme-031854 Drosophila melanogaster 49.32 3.00e-71 259.00
IUUC-Ete-032618 Echinops telfairi 42.86 1.00e-36 144.00
IUUC-Eca-033268 Equus caballus 50.33 1.00e-79 287.00
IUUC-Fca-035918 Felis catus 50.33 2.00e-79 286.00
IUUC-Fal-037551 Ficedula albicollis 50.67 3.00e-76 276.00
IUUC-Fox-037763 Fusarium oxysporum 70.47 1.00e-124 437.00
IUUC-Fso-038341 Fusarium solani 70.27 4.00e-123 431.00
IUUC-Gmo-038638 Gadus morhua 50.00 3.00e-80 290.00
IUUC-Ggr-039865 Gaeumannomyces graminis 70.13 2.00e-123 432.00
IUUC-Gga-040193 Gallus gallus 51.00 2.00e-81 293.00
IUUC-Gac-041337 Gasterosteus aculeatus 32.57 3.00e-32 130.00
IUUC-Gma-044311 Glycine max 49.66 5.00e-75 272.00
IUUC-Ggo-045252 Gorilla gorilla 51.00 2.00e-80 290.00
IUUC-Hsa-046565 Homo sapiens 51.00 2.00e-80 290.00
IUUC-Hvu-047835 Hordeum vulgare 49.83 1.00e-76 278.00
IUUC-Itr-048587 Ictidomys tridecemlineatus 50.67 8.00e-80 288.00
IUUC-Kpa-049148 Komagataella pastoris 58.39 2.00e-95 339.00
IUUC-Lch-050421 Latimeria chalumnae 52.33 4.00e-83 299.00
IUUC-Lpe-051187 Leersia perrieri 47.33 1.00e-75 276.00
IUUC-Loc-052167 Lepisosteus oculatus 50.67 1.00e-82 297.00
IUUC-Lma-053250 Leptosphaeria maculans 69.49 3.00e-118 415.00
IUUC-Laf-054304 Loxodonta africana 50.33 2.00e-80 290.00
IUUC-Mcc-055519 Macaca mulatta 51.00 2.00e-80 290.00
IUUC-Meu-056439 Macropus eugenii 50.33 7.00e-81 291.00
IUUC-Mor-057241 Magnaporthe oryzae 70.71 8.00e-124 434.00
IUUC-Mpo-057373 Magnaporthe poae 62.37 2.00e-100 356.00
IUUC-Mtr-058412 Medicago truncatula 47.81 8.00e-73 265.00
IUUC-Mla-058966 Melampsora laricipopulina 50.93 3.00e-88 316.00
IUUC-Mga-060066 Meleagris gallopavo 51.17 4.00e-81 292.00
IUUC-Mvi-060290 Microbotryum violaceum 53.73 2.00e-87 316.00
IUUC-Mmr-060717 Microcebus murinus 50.67 3.00e-80 289.00
IUUC-Mdo-062496 Monodelphis domestica 50.00 1.00e-80 291.00
IUUC-Mmu-063490 Mus musculus 50.67 4.00e-80 289.00
IUUC-Mac-064519 Musa acuminata 47.99 8.00e-73 265.00
IUUC-Mpu-066601 Mustela putorius furo 50.33 1.00e-79 288.00
IUUC-Mlu-067501 Myotis lucifugus 50.33 6.00e-80 288.00
IUUC-Nfi-068360 Neosartorya fischeri 95.33 2.00e-145 505.00
IUUC-Ncr-068928 Neurospora crassa 71.38 6.00e-128 447.00
IUUC-Nle-069028 Nomascus leucogenys 50.67 3.00e-80 290.00
IUUC-Opr-070446 Ochotona princeps 50.84 3.00e-79 286.00
IUUC-Ont-071587 Oreochromis niloticus 52.00 5.00e-83 298.00
IUUC-Oan-073211 Ornithorhynchus anatinus 49.33 3.00e-79 286.00
IUUC-Ocu-074306 Oryctolagus cuniculus 51.00 4.00e-80 289.00
IUUC-Oba-075069 Oryza barthii 48.50 4.00e-75 272.00
IUUC-Obr-076667 Oryza brachyantha 49.17 5.00e-76 275.00
IUUC-Ogl-077208 Oryza glaberrima 48.50 4.00e-75 272.00
IUUC-Ogu-078513 Oryza glumaepatula 48.50 4.00e-75 272.00
IUUC-Oin-079094 Oryza indica 48.50 4.00e-75 272.00
IUUC-Olo-080473 Oryza longistaminata 48.50 4.00e-75 272.00
IUUC-Ome-081643 Oryza meridionalis 48.50 4.00e-75 272.00
IUUC-Oni-082589 Oryza nivara 48.50 4.00e-75 272.00
IUUC-Opu-083677 Oryza punctata 48.33 3.00e-75 273.00
IUUC-Oru-084537 Oryza rufipogon 48.50 4.00e-75 272.00
IUUC-Osa-085449 Oryza sativa 48.50 4.00e-75 272.00
IUUC-Ola-087226 Oryzias latipes 51.33 4.00e-82 296.00
IUUC-Olu-087893 Ostreococcus lucimarinus 50.00 3.00e-68 249.00
IUUC-Oga-088837 Otolemur garnettii 50.33 8.00e-80 288.00
IUUC-Oar-089594 Ovis aries 50.67 2.00e-79 286.00
IUUC-Ptr-091132 Pan troglodytes 51.00 2.00e-80 290.00
IUUC-Pan-092013 Papio anubis 31.56 6.00e-25 105.00
IUUC-Psi-093568 Pelodiscus sinensis 50.67 4.00e-81 292.00
IUUC-Pma-094172 Petromyzon marinus 46.79 8.00e-33 130.00
IUUC-Pno-094955 Phaeosphaeria nodorum 69.05 3.00e-117 412.00
IUUC-Ppa-095835 Physcomitrella patens 50.00 5.00e-74 269.00
IUUC-Pfo-096063 Poecilia formosa 52.00 2.00e-82 296.00
IUUC-Pab-098674 Pongo abelii 50.67 2.00e-79 287.00
IUUC-Pop-099402 Populus trichocarpa 46.98 3.00e-71 259.00
IUUC-Pca-100824 Procavia capensis 37.46 3.00e-54 203.00
IUUC-Ppe-101278 Prunus persica 47.51 3.00e-70 256.00
IUUC-Pva-103161 Pteropus vampyrus 46.33 5.00e-72 262.00
IUUC-Pgr-103573 Puccinia graminis 51.27 2.00e-86 310.00
IUUC-Ptt-103700 Puccinia triticina 50.00 8.00e-84 301.00
IUUC-Pte-104267 Pyrenophora teres 67.56 2.00e-113 400.00
IUUC-Pyt-104535 Pyrenophora triticirepentis 67.46 1.00e-107 380.00
IUUC-Rno-104833 Rattus norvegicus 50.67 5.00e-80 288.00
IUUC-Sce-106437 Saccharomyces cerevisiae 59.40 3.00e-93 332.00
IUUC-Sha-106611 Sarcophilus harrisii 50.33 7.00e-81 291.00
IUUC-Sja-107654 Schizosaccharomyces japonicus 54.88 1.00e-88 317.00
IUUC-Spo-108362 Schizosaccharomyces pombe 53.56 9.00e-84 301.00
IUUC-Smo-108797 Selaginella moellendorffii 49.50 9.00e-74 268.00
IUUC-Sit-110132 Setaria italica 49.00 5.00e-76 275.00
IUUC-Sly-111852 Solanum lycopersicum 47.67 4.00e-70 256.00
IUUC-Stu-112195 Solanum tuberosum 48.67 1.00e-71 261.00
IUUC-Sar-113279 Sorex araneus 30.11 2.00e-23 101.00
IUUC-Sbi-114229 Sorghum bicolor 50.33 2.00e-77 280.00
IUUC-Sre-114898 Sporisorium reilianum 47.65 4.00e-82 296.00
IUUC-Ssc-115995 Sus scrofa 51.56 2.00e-36 142.00
IUUC-Tgu-116793 Taeniopygia guttata 50.67 4.00e-76 276.00
IUUC-Tru-117797 Takifugu rubripes 51.00 8.00e-82 295.00
IUUC-Tsy-118913 Tarsius syrichta 29.96 5.00e-21 93.20
IUUC-Tni-120366 Tetraodon nigroviridis 52.33 1.00e-83 301.00
IUUC-Tca-121068 Theobroma cacao 47.96 4.00e-72 262.00
IUUC-Tre-121899 Trichoderma reesei 70.03 4.00e-123 432.00
IUUC-Tvi-122380 Trichoderma virens 70.71 6.00e-124 434.00
IUUC-Tae-123998 Triticum aestivum 49.83 1.00e-77 281.00
IUUC-Tur-126202 Triticum urartu 49.50 9.00e-77 278.00
IUUC-Tme-127181 Tuber melanosporum 59.35 1.00e-102 364.00
IUUC-Ttr-128448 Tursiops truncatus 49.62 2.00e-64 237.00
IUUC-Uma-129661 Ustilago maydis 48.21 9.00e-83 298.00
IUUC-Vda-129666 Verticillium dahliae 70.37 2.00e-119 419.00
IUUC-Vpa-130318 Vicugna pacos 50.33 1.00e-79 287.00
IUUC-Vvi-130868 Vitis vinifera 48.66 4.00e-74 269.00
IUUC-Xtr-131859 Xenopus tropicalis 51.00 7.00e-82 295.00
IUUC-Xma-133898 Xiphophorus maculatus 52.33 5.00e-83 299.00
IUUC-Yli-134559 Yarrowia lipolytica 59.60 2.00e-95 340.00
Created Date 25-Jun-2017

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