iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000040571.7	ENSDART00000059376.6	ENSDARP00000059375.5
ENSDARG00000040571.7	ENSDART00000148311.1	ENSDARP00000119015.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.70e-21	77.0	995	1067

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceenss 74
            p+efl+pI+ +lM dPv lp s++t+drs+I+++l s+++ +P++r+plt +++ Pn +lr+ i +w++++++
   Q: 995  APDEFLDPIMSTLMLDPVLLPsSNVTVDRSTIARHLLSDQT-DPFNRSPLTMDQIRPNEELRQQIMKWLADHKQ 1067
           79**************************************9.****************************9986 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MTDQGNNNQN ISQNPFAALF SSVADAKQFA SDQKQQRPTE QQSVDSGESQ SESENSASES 60
IDENDDSVAE ISRSFRSRQE LCEQLNVNHM IQRIFLITLD NSDPSLRSGN GIPPRCVYLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAAGAGTC TGCAGGACTG TCTGAAAAGA CATTGAAAAG AGCAGAACAG CATTTCAAAC 60
TGCAGCAGAC CTCATAATAA AAAAGCTAAC GGTAAGTTTA ATATTTGATC CAACTTACGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR019474--Ub_conjug_fac_E4_core
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX

Pfam

PF04564--U-box
PF10408--Ufd2P_core

SMART

SM00504--Ubox

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0000209--P:protein polyubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001281	Ailuropoda melanoleuca	76.44	0.00e+00	1605.00
IUUC-Apl-003514	Anas platyrhynchos	80.04	0.00e+00	1657.00
IUUC-Aca-005167	Anolis carolinensis	76.38	0.00e+00	1541.00
IUUC-Ame-010905	Astyanax mexicanus	87.62	0.00e+00	849.00
IUUC-Bta-012413	Bos taurus	76.47	0.00e+00	1615.00
IUUC-Cja-019715	Callithrix jacchus	76.37	0.00e+00	1622.00
IUUC-Cfa-021185	Canis familiaris	77.24	0.00e+00	1655.00
IUUC-Cpo-021516	Cavia porcellus	76.79	0.00e+00	1617.00
IUUC-Csa-023765	Chlorocebus sabaeus	77.33	0.00e+00	1616.00
IUUC-Cho-024614	Choloepus hoffmanni	82.27	0.00e+00	731.00
IUUC-Cin-025532	Ciona intestinalis	37.29	2.00e-164	573.00
IUUC-Csv-025834	Ciona savignyi	50.97	3.00e-46	177.00
IUUC-Dno-029785	Dasypus novemcinctus	77.54	0.00e+00	1631.00
IUUC-Dor-030421	Dipodomys ordii	73.75	0.00e+00	1521.00
IUUC-Dme-031715	Drosophila melanogaster	33.71	3.00e-125	442.00
IUUC-Ete-032767	Echinops telfairi	74.20	0.00e+00	1011.00
IUUC-Eca-033587	Equus caballus	77.12	0.00e+00	1627.00
IUUC-Fca-035622	Felis catus	75.88	0.00e+00	1641.00
IUUC-Fal-037262	Ficedula albicollis	77.58	0.00e+00	1637.00
IUUC-Gmo-038686	Gadus morhua	83.97	0.00e+00	1767.00
IUUC-Gga-041222	Gallus gallus	78.60	0.00e+00	1687.00
IUUC-Gac-042637	Gasterosteus aculeatus	84.33	0.00e+00	1748.00
IUUC-Ggo-044685	Gorilla gorilla	76.65	0.00e+00	1625.00
IUUC-Hsa-046176	Homo sapiens	77.24	0.00e+00	1627.00
IUUC-Itr-048469	Ictidomys tridecemlineatus	79.93	0.00e+00	862.00
IUUC-Lch-049630	Latimeria chalumnae	77.26	0.00e+00	1632.00
IUUC-Loc-052727	Lepisosteus oculatus	85.21	0.00e+00	1807.00
IUUC-Laf-054041	Loxodonta africana	76.08	0.00e+00	1644.00
IUUC-Mcc-055099	Macaca mulatta	76.31	0.00e+00	1621.00
IUUC-Meu-055991	Macropus eugenii	76.65	0.00e+00	1627.00
IUUC-Mga-059596	Meleagris gallopavo	78.76	0.00e+00	1572.00
IUUC-Mmr-061244	Microcebus murinus	75.31	0.00e+00	1313.00
IUUC-Mdo-062335	Monodelphis domestica	76.96	0.00e+00	1612.00
IUUC-Mmu-063572	Mus musculus	75.37	0.00e+00	1605.00
IUUC-Mpu-066444	Mustela putorius furo	73.09	0.00e+00	1545.00
IUUC-Mlu-068232	Myotis lucifugus	76.77	0.00e+00	1615.00
IUUC-Nle-070036	Nomascus leucogenys	76.55	0.00e+00	1622.00
IUUC-Opr-070503	Ochotona princeps	70.03	0.00e+00	1030.00
IUUC-Ont-072389	Oreochromis niloticus	86.82	0.00e+00	1842.00
IUUC-Oan-073114	Ornithorhynchus anatinus	77.15	0.00e+00	1479.00
IUUC-Ocu-074370	Oryctolagus cuniculus	77.37	0.00e+00	1452.00
IUUC-Ola-086562	Oryzias latipes	84.14	0.00e+00	1765.00
IUUC-Oga-088146	Otolemur garnettii	76.64	0.00e+00	1612.00
IUUC-Oar-089190	Ovis aries	76.49	0.00e+00	1599.00
IUUC-Ptr-090592	Pan troglodytes	76.46	0.00e+00	1620.00
IUUC-Pan-092271	Papio anubis	77.24	0.00e+00	1628.00
IUUC-Psi-093730	Pelodiscus sinensis	76.99	0.00e+00	1647.00
IUUC-Pma-094120	Petromyzon marinus	72.81	1.00e-130	459.00
IUUC-Pfo-097077	Poecilia formosa	81.63	0.00e+00	1754.00
IUUC-Pab-098069	Pongo abelii	76.55	0.00e+00	1603.00
IUUC-Pca-100762	Procavia capensis	74.49	0.00e+00	1551.00
IUUC-Pva-103149	Pteropus vampyrus	76.09	0.00e+00	1620.00
IUUC-Rno-105342	Rattus norvegicus	75.21	0.00e+00	1603.00
IUUC-Sha-106555	Sarcophilus harrisii	77.71	0.00e+00	1655.00
IUUC-Sly-110848	Solanum lycopersicum	38.69	2.00e-73	270.00
IUUC-Sar-113131	Sorex araneus	74.39	0.00e+00	966.00
IUUC-Ssc-115841	Sus scrofa	76.94	0.00e+00	1625.00
IUUC-Tgu-116823	Taeniopygia guttata	77.42	0.00e+00	1614.00
IUUC-Tru-118249	Takifugu rubripes	82.78	0.00e+00	1781.00
IUUC-Tsy-119112	Tarsius syrichta	75.13	3.00e-160	559.00
IUUC-Tni-119848	Tetraodon nigroviridis	82.95	0.00e+00	1764.00
IUUC-Tbe-127889	Tupaia belangeri	65.54	0.00e+00	660.00
IUUC-Ttr-129300	Tursiops truncatus	72.14	0.00e+00	811.00
IUUC-Vpa-130215	Vicugna pacos	75.51	0.00e+00	1618.00
IUUC-Xtr-132107	Xenopus tropicalis	74.01	0.00e+00	1561.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence