iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-024063

Ensembl Protein ID

ENSCSAP00000000389.1

UniProt Accession

A0A0D9QVK0; A0A0D9QVK0_CHLSB

Genbank Protein ID

ENSCSAP00000000389

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01117786

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000004032.1	ENSCSAT00000002061.1	ENSCSAP00000000389.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	7.60e-130	433.1	141	473

Active Site

Position(s)	Description	Evidence
442	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dl krl+++f+gEegld+gGv+re+l+lls+e+ np++glf+ys +d +tlq+npds + npehl++F+f+Gr++g+a+++g+++d 
   Q: 141  PKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAV-NPEHLSYFHFVGRIMGMAVFHGHYIDG 228
           678999*****************************************************98.89************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
            ++ +fyk+llgk+++l+d+e vdp+l++sl +i+en   di+   ld tf+v+++ +ge+ ++eLkp+G++ipV++eNk+eYv+l+v+
   Q: 229  GFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILEN---DITGV-LDHTFCVEHNAYGEIIQHELKPNGKSIPVNEENKKEYVRLYVN 313
           ***********************************99...9***8.******************************************* PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +r+ +gi+ q+ a+++Gfnevip++ll+ F+e+elel+icG  +idv+d+k +t+ k+ +t+ds+ ++wFw+++e f++e r+++LqFv
   Q: 314  WRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKELELIICGLGKIDVSDWKVNTRLKH-CTPDSNIVKWFWKAVEFFDEERRARLLQFV 401
           ********************************************************99.****************************** PP
   S: 269  TgssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           Tgssr+Pl+Gf++l+    prlf+i++ da +++lP+++TCfn++++P+Y+s+e+l+ekLl+Aieet gF +
   Q: 402  TGSSRVPLQGFKALQgaagPRLFTIHQiDACTNNLPKAHTCFNRIDIPPYESYEKLYEKLLTAIEETCGFAV 473
           **********************************************************************76 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MRYFLFYICF CRDLSNINCE ELGPLPPGWE IRNTATGRVY FVDHNNRTTQ FTDPRLSANL 60
HLVLNRQNQL KDQQQQQVVS LCPDDTECLT VPRYKRDLVQ KLKILRQELS QQQPQAGHCR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGGCAA ATATTGTGAT TGATTTTATA TTAGTTTAAA TCTGTATTAC ATTAAAGCCT 60
AGGAACTTAC TAAAAAATGT AGACTATGTG ATAAGTTTTT CTGAGCCATT TATGGATTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00632--HECT
PF00397--WW

SMART

SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cho-024804	Choloepus hoffmanni	99.03	0.00e+00	642.00
IUUC-Fca-036047	Felis catus	99.14	0.00e+00	931.00
IUUC-Ggo-044449	Gorilla gorilla	99.75	0.00e+00	826.00
IUUC-Itr-048042	Ictidomys tridecemlineatus	99.14	0.00e+00	932.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence