iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sar-113421

Ensembl Protein ID

ENSSARP00000000188.1

UniProt Accession

B3EX20; B3EX20_SORAR

Genbank Protein ID

ACE60216.1

Protein Name

Intersectin-1 (Predicted)

Genbank Nucleotide ID

DP000755

Gene Name

ITSN1; ITSN1_2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSARG00000000205.1	ENSSART00000000206.1	ENSSARP00000000188.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.10e-35	118.7	1006	1056

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            ++++y ye++++++Lt+++Gdv+lv    ++d++W+ g      k G+fP+n+v+
   Q: 1006 XFIAMYTYESSEQGDLTFQQGDVILVT---KKDGDWWTG--AVGAKTGVFPSNYVR 1056
           5789**********************7...*********..8999*********97 PP

Organism

Sorex araneus

Protein Sequence
(Fasta)

MAQFPAPFGG SLDIWAITVE ERAKHDQQFH SLKPISGFIT GDQARNFFFQ SGLPQPVLAQ 60
IWALADMNND GRMDQVEFSI AMKLIKLKLQ GYQLPATLPP AMKQQPVALP TAPTFXXXXX 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCAGT TCCCAGCACC TTTTGGAGGT AAGATTGCAG AGACTTTCCT CTTTTTTTAG 60
AGTATTGTAT AACGATTCTT TGAATTACGG TATGACACAT TTCAGTGATA AACAAAAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0344--Guanine-nucleotide releasing factor

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain

PROSITE

PS50004--C2
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN

Pfam

PF00168--C2
PF16652--PH_13
PF00621--RhoGEF

SMART

SM00239--C2
SM00233--PH
SM00325--RhoGEF

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011878	Astyanax mexicanus	84.15	0.00e+00	723.00
IUUC-Cpo-021352	Cavia porcellus	88.32	0.00e+00	751.00
IUUC-Csa-024033	Chlorocebus sabaeus	88.32	0.00e+00	746.00
IUUC-Cho-024969	Choloepus hoffmanni	86.67	0.00e+00	665.00
IUUC-Cin-025435	Ciona intestinalis	55.37	2.00e-129	457.00
IUUC-Csv-026290	Ciona savignyi	56.10	2.00e-132	465.00
IUUC-Cne-026918	Cryptococcus neoformans	33.33	9.00e-28	119.00
IUUC-Cme-027247	Cyanidioschyzon merolae	29.27	4.00e-09	55.80
IUUC-Dre-028623	Danio rerio	83.17	0.00e+00	714.00
IUUC-Dor-030272	Dipodomys ordii	88.08	0.00e+00	743.00
IUUC-Ete-032927	Echinops telfairi	87.83	0.00e+00	747.00
IUUC-Eeu-034977	Erinaceus europaeus	61.63	6.00e-166	578.00
IUUC-Gmo-039632	Gadus morhua	80.53	0.00e+00	634.00
IUUC-Loc-052613	Lepisosteus oculatus	84.43	0.00e+00	726.00
IUUC-Mla-059128	Melampsora laricipopulina	30.57	8.00e-32	133.00
IUUC-Mga-059194	Meleagris gallopavo	86.89	0.00e+00	735.00
IUUC-Mvi-060268	Microbotryum violaceum	30.52	1.00e-29	125.00
IUUC-Nle-069448	Nomascus leucogenys	62.65	9.00e-167	580.00
IUUC-Pfo-097486	Poecilia formosa	81.27	0.00e+00	705.00
IUUC-Pab-098281	Pongo abelii	81.51	0.00e+00	674.00
IUUC-Pva-102335	Pteropus vampyrus	87.59	0.00e+00	750.00
IUUC-Pgr-103473	Puccinia graminis	29.17	3.00e-27	117.00
IUUC-Sre-115028	Sporisorium reilianum	32.32	2.00e-22	102.00
IUUC-Ssc-116237	Sus scrofa	63.62	8.00e-173	600.00
IUUC-Tru-117789	Takifugu rubripes	81.75	0.00e+00	705.00
IUUC-Tsy-119039	Tarsius syrichta	80.54	0.00e+00	660.00
IUUC-Tni-119952	Tetraodon nigroviridis	81.31	0.00e+00	699.00
IUUC-Tbe-127754	Tupaia belangeri	66.12	9.00e-149	521.00
IUUC-Uma-129456	Ustilago maydis	27.44	1.00e-20	95.90
IUUC-Vpa-130687	Vicugna pacos	62.45	7.00e-171	594.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence