iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036985

Ensembl Protein ID

ENSFALP00000005585.1

UniProt Accession

U3JS31; U3JS31_FICAL

Genbank Protein ID

ENSFALP00000005585

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01010994

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000005365.1	ENSFALT00000005612.1	ENSFALP00000005585.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.60e-108	361.1	707	1527

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++ + ++  +ln++np ++kg+++k++ +l++elw++++k+++p +l  +++k+a++f+g
   Q: 707  TGLSNLGNTCFMNSSIQCVSNTQPLTRYFISgRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKNIAPLKLRWTIAKYAPRFNG 793
           7******************************9******************************************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a+e++ ++n+s+++dlF+gqlksq+kc++c+++s+r++p
   Q: 794  FQQQDSQELLAFLLDGLHEDLNRVHDKPYVELKDSD--GRPDWevaaeAWENHLRRNRSIVVDLFHGQLKSQVKCKTCGHISVRFDP 878
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++ +++e                                                                      
   Q: 879  FNFLSLPLPMDSYMHLEitvikldgttpvryglrlnmdekytglkkqlselcglkpeqillaevhssniknfpqdnqkvrlsvsgfl 965
           *************9999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 966  cafeipipgsptsasspvqteistgpaangapsilmngdvpkpslipngmpntvvpswslnghvaslcdspctgyiiavhrkmmrte 1052
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1053 lyflssqknrpslfgmplivpctvhtrkrdlydavwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvqkdgnscawcpwyr 1139
           *************************************************************************************** PP
   S: 186  ...........................................................slqdcLesftkeeelegenkyycekckk 213
                                                                      +l++cL++ft+eeel ++++yyc+kck 
   Q: 1140 fcrgckiectedracvgnayiavdwdptalhlryqtsqeriveehesveqsrraqaepiNLDSCLRAFTSEEELGEDEMYYCSKCKT 1226
           *************************************************************************************** PP
   S: 214  kqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts................................ 267
           ++ a+kkl+l++lP++Li+hLkRf+f +   + +k +k v+fp+e +d s f+++                                
   Q: 1227 HCLATKKLDLWRLPPILIIHLKRFQFVNG--RWIKSQKIVKFPREnFDPSAFLVQrdpshfqrkqltlqvenlpearagqgdsrktd 1311
           ************************99775..5569********************89999998888888888888888888888888 PP
   S: 268  ............................................................................peekqke.... 274
                                                                                       +     +    
   Q: 1312 vqitgtaaegdtlnrspsslnttvlnnvkaspslgrksgtscpssknsspnssprtlgrgkgrlrlpqlgknklssS-----Kenla 1393
           88888888888888888888877777777777777777777776666666666666666666666655555555550.....05555 PP
   S: 275  .........................................................................kkkYeLiavvvHsG 288
                                                                                    + +Y+L+a+ +HsG
   Q: 1394 anrengaeheqgdaltkgqalggsqgelepgqdsegalangflweqsslsngqgtethseddtaddqrddawvNPIYNLYAISCHSG 1480
           5555556666666666666666666666677777777777777777777777778888888888899999999************** PP
   S: 289  slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
            +++GHYv+y+kn ++kW++++Ds+++e++ +e+ +   ++aY+lfY+++
   Q: 1481 IMGGGHYVTYAKNPNNKWYCYNDSSCKELHPDEIDT---DSAYILFYEQQ 1527
           ************************************...********985 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MTQQCFIREV LGDGVPPKVA EVIYCSFGGI SKGLHFNNLI VGLVLLTRGR EEEKTKYIFS 60
LFSNESGSYV VREEMEKMLH VVDGKVPESL KKCFSEGEKV NYEKFRVWLL HNKDAFTFSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTTTATTG ACCAATTTTT TTTTCTTTCC TCTGTCCTCA GTTACAGACA TAGAACTGAA 60
GAGGCTCAAA GATGCTTTCA AGAGAACTTG TGGCCTCTCC TATTATATGA CCCAGCAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	83.86	0.00e+00	2268.00
IUUC-Apl-003272	Anas platyrhynchos	90.53	0.00e+00	2824.00
IUUC-Aca-005057	Anolis carolinensis	83.85	0.00e+00	2259.00
IUUC-Ame-010781	Astyanax mexicanus	74.02	0.00e+00	2301.00
IUUC-Bta-013502	Bos taurus	80.53	0.00e+00	2455.00
IUUC-Cel-018710	Caenorhabditis elegans	29.18	4.00e-81	296.00
IUUC-Cja-018754	Callithrix jacchus	84.30	0.00e+00	2629.00
IUUC-Cfa-020526	Canis familiaris	84.49	0.00e+00	2637.00
IUUC-Cpo-021568	Cavia porcellus	79.91	0.00e+00	2406.00
IUUC-Csa-023143	Chlorocebus sabaeus	83.80	0.00e+00	2581.00
IUUC-Cho-024603	Choloepus hoffmanni	53.52	3.00e-156	546.00
IUUC-Cin-025583	Ciona intestinalis	54.16	0.00e+00	872.00
IUUC-Csv-026344	Ciona savignyi	46.47	0.00e+00	1136.00
IUUC-Dre-028121	Danio rerio	75.85	0.00e+00	2289.00
IUUC-Dno-029911	Dasypus novemcinctus	83.47	0.00e+00	2609.00
IUUC-Dor-030608	Dipodomys ordii	61.61	0.00e+00	637.00
IUUC-Dme-032094	Drosophila melanogaster	44.61	1.00e-122	435.00
IUUC-Ete-032639	Echinops telfairi	80.37	0.00e+00	1338.00
IUUC-Eca-034253	Equus caballus	84.25	0.00e+00	2612.00
IUUC-Eeu-035084	Erinaceus europaeus	75.89	0.00e+00	1425.00
IUUC-Fca-035474	Felis catus	82.33	0.00e+00	2122.00
IUUC-Gmo-039568	Gadus morhua	80.03	0.00e+00	2044.00
IUUC-Gga-040509	Gallus gallus	89.16	0.00e+00	2791.00
IUUC-Gac-041757	Gasterosteus aculeatus	79.21	0.00e+00	2092.00
IUUC-Ggo-044956	Gorilla gorilla	74.46	0.00e+00	2060.00
IUUC-Hsa-046107	Homo sapiens	84.05	0.00e+00	2600.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	77.74	0.00e+00	949.00
IUUC-Lch-050681	Latimeria chalumnae	77.27	0.00e+00	2355.00
IUUC-Loc-052474	Lepisosteus oculatus	78.66	0.00e+00	2450.00
IUUC-Laf-054273	Loxodonta africana	84.25	0.00e+00	2606.00
IUUC-Mcc-054718	Macaca mulatta	83.99	0.00e+00	2605.00
IUUC-Meu-056558	Macropus eugenii	69.07	0.00e+00	1282.00
IUUC-Mga-059892	Meleagris gallopavo	91.32	0.00e+00	2814.00
IUUC-Mmr-060866	Microcebus murinus	84.81	0.00e+00	2653.00
IUUC-Mdo-062607	Monodelphis domestica	85.30	0.00e+00	2682.00
IUUC-Mmu-063797	Mus musculus	84.30	0.00e+00	2654.00
IUUC-Mpu-066121	Mustela putorius furo	84.30	0.00e+00	2652.00
IUUC-Mlu-067581	Myotis lucifugus	83.75	0.00e+00	2640.00
IUUC-Nle-069916	Nomascus leucogenys	81.91	0.00e+00	2511.00
IUUC-Opr-071073	Ochotona princeps	75.25	0.00e+00	1046.00
IUUC-Ont-071310	Oreochromis niloticus	80.59	0.00e+00	2088.00
IUUC-Oan-073356	Ornithorhynchus anatinus	84.63	0.00e+00	2645.00
IUUC-Ocu-074216	Oryctolagus cuniculus	84.66	0.00e+00	2630.00
IUUC-Ola-087434	Oryzias latipes	73.64	0.00e+00	2241.00
IUUC-Oga-089034	Otolemur garnettii	84.52	0.00e+00	2585.00
IUUC-Oar-090369	Ovis aries	84.24	0.00e+00	2677.00
IUUC-Ptr-090605	Pan troglodytes	84.18	0.00e+00	2605.00
IUUC-Pan-092381	Papio anubis	83.89	0.00e+00	2598.00
IUUC-Psi-093819	Pelodiscus sinensis	87.55	0.00e+00	2763.00
IUUC-Pma-094480	Petromyzon marinus	62.78	0.00e+00	1427.00
IUUC-Pfo-096561	Poecilia formosa	73.13	0.00e+00	2226.00
IUUC-Pab-097643	Pongo abelii	83.90	0.00e+00	2555.00
IUUC-Pca-100944	Procavia capensis	68.76	0.00e+00	906.00
IUUC-Pva-102732	Pteropus vampyrus	74.60	0.00e+00	2260.00
IUUC-Rno-105113	Rattus norvegicus	83.92	0.00e+00	2631.00
IUUC-Sha-107608	Sarcophilus harrisii	74.87	1.00e-153	535.00
IUUC-Sar-113201	Sorex araneus	73.68	0.00e+00	1476.00
IUUC-Ssc-115469	Sus scrofa	74.42	6.00e-145	506.00
IUUC-Tgu-117322	Taeniopygia guttata	97.20	0.00e+00	3044.00
IUUC-Tru-118705	Takifugu rubripes	61.20	0.00e+00	944.00
IUUC-Tsy-119433	Tarsius syrichta	72.36	0.00e+00	1283.00
IUUC-Tni-120631	Tetraodon nigroviridis	79.20	0.00e+00	2071.00
IUUC-Tbe-127553	Tupaia belangeri	82.26	8.00e-176	611.00
IUUC-Ttr-128260	Tursiops truncatus	83.24	0.00e+00	2635.00
IUUC-Vpa-130479	Vicugna pacos	79.44	0.00e+00	2432.00
IUUC-Xtr-132686	Xenopus tropicalis	82.39	0.00e+00	2531.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence