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Basic Information Integrated Annotations

Tag Content
iUUCD ID IUUC-Dme-032153
Ensembl Protein ID FBpp0086941
UniProt Accession Q7KLE5; Q7KLE5_DROME
Genbank Protein ID AAD46684.1; AAF58486.1; AAL28826.1; CAB45188.1
Protein Name Amphiphysin; Amphiphysin, isoform A; LD19810p
Genbank Nucleotide ID AF171225; AE013599; AY061278; AJ242855
Gene Name Amph; Amp; CG8604; Dmel_CG8604
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0027356 FBtr0333099 FBpp0305312
FBgn0027356 FBtr0087828 FBpp0086941
FBgn0027356 FBtr0333100 FBpp0305313
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexPINAMentha
Protein 3D Structure
PDBMMDB
Post-translational Modifications (PTMs)
dbPAFPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 1.50e-17 63.3 540 602
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlvi...ekeeqdegWlkgvkelegkrGlfPenFvekl 62
    +++v++ y y ++ deL+++ Gd ++vi ++e+q+egWl+g+ke ++ +GlfP+nF++ +
   Q: 540 LYRVKATYGYAKEDVDELSFEIGDLIRVIeydDPEDQEEGWLMGQKEGTNEKGLFPANFTRPI 602
    789***************************999***************************975 PP
   

Organism Drosophila melanogaster
Protein Sequence
(Fasta)
MTENKGIMLA KSVQKHAGRA KEKILQNLGK VDRTADEIFD DHLNNFNRQQ ASANRLQKEF 60
NNYIRCVRAA QAASKTLMDS VCEIYEPQWS GYDALQAQTG ASESLWADFA HKLGDQVLIP 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Dme-032153|UBD,SH3|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTGAAGTCGC GTTCTCTCGT TTATCACCGT CGTCTTCCAC GCACATTCGT CGCCTTTTCT 60
TCTCCGTTCG TCCGTCGACT ACTTGTGCCA TTTGTTTTGA ATATTCCGAG CGAATTCGAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Dme-032153|UBD,SH3|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR003005--Amphiphysin
IPR004148--BAR_dom
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS50002--SH3

Pfam

PF03114--BAR
PF14604--SH3_9

PRINTS

PR01251--AMPHIPHYSIN

SMART

SM00721--BAR
SM00326--SH3

Gene Ontology

GO:0032154--C:cleavage furrow
GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0098793--C:presynapse
GO:0045202--C:synapse
GO:0005543--F:phospholipid binding
GO:0006887--P:exocytosis
GO:0007269--P:neurotransmitter secretion
GO:0008104--P:protein localization
GO:0006937--P:regulation of muscle contraction
GO:0042052--P:rhabdomere development
GO:0045313--P:rhabdomere membrane biogenesis
GO:0048488--P:synaptic vesicle endocytosis

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001261 Ailuropoda melanoleuca 40.08 1.00e-53 203.00
IUUC-Apl-003820 Anas platyrhynchos 41.26 2.00e-51 196.00
IUUC-Aca-004603 Anolis carolinensis 41.77 1.00e-56 213.00
IUUC-Acl-008143 Aspergillus clavatus 28.02 6.00e-18 83.60
IUUC-Afu-008953 Aspergillus fumigatus 28.45 8.00e-19 86.30
IUUC-Ani-009357 Aspergillus nidulans 30.10 4.00e-17 80.50
IUUC-Ang-009877 Aspergillus niger 28.45 8.00e-19 86.30
IUUC-Ate-010244 Aspergillus terreus 28.09 2.00e-18 85.10
IUUC-Ame-010666 Astyanax mexicanus 42.62 7.00e-55 207.00
IUUC-Bgr-012176 Blumeria graminis 27.03 1.00e-15 75.90
IUUC-Bta-013010 Bos taurus 40.08 1.00e-53 203.00
IUUC-Bci-013618 Botrytis cinerea 26.67 2.00e-16 78.60
IUUC-Cel-018166 Caenorhabditis elegans 36.71 1.00e-41 163.00
IUUC-Cja-019833 Callithrix jacchus 40.17 7.00e-53 201.00
IUUC-Cfa-020825 Canis familiaris 35.97 1.00e-43 170.00
IUUC-Cpo-021536 Cavia porcellus 35.78 2.00e-39 156.00
IUUC-Csa-023301 Chlorocebus sabaeus 36.33 3.00e-50 192.00
IUUC-Cho-024492 Choloepus hoffmanni 34.98 6.00e-37 148.00
IUUC-Cin-025739 Ciona intestinalis 33.88 9.00e-39 154.00
IUUC-Csv-026073 Ciona savignyi 36.00 1.00e-41 163.00
IUUC-Dre-028065 Danio rerio 41.77 1.00e-52 201.00
IUUC-Dno-029712 Dasypus novemcinctus 37.05 4.00e-50 191.00
IUUC-Dor-030535 Dipodomys ordii 38.82 6.00e-51 194.00
IUUC-Dse-031269 Dothistroma septosporum 27.16 2.00e-19 88.60
IUUC-Ete-032582 Echinops telfairi 31.14 2.00e-26 113.00
IUUC-Eca-033701 Equus caballus 37.39 1.00e-48 186.00
IUUC-Eeu-034674 Erinaceus europaeus 40.08 5.00e-53 201.00
IUUC-Fca-036228 Felis catus 40.89 4.00e-50 192.00
IUUC-Fal-037539 Ficedula albicollis 36.30 2.00e-48 186.00
IUUC-Fox-037819 Fusarium oxysporum 27.11 3.00e-16 77.80
IUUC-Gmo-038933 Gadus morhua 42.26 9.00e-52 197.00
IUUC-Gga-041211 Gallus gallus 41.35 2.00e-55 209.00
IUUC-Gac-041862 Gasterosteus aculeatus 40.66 2.00e-50 193.00
IUUC-Ggo-045200 Gorilla gorilla 38.43 3.00e-53 202.00
IUUC-Hsa-046142 Homo sapiens 38.34 3.00e-54 205.00
IUUC-Hvu-047857 Hordeum vulgare 25.00 3.60e+00 25.00
IUUC-Itr-048478 Ictidomys tridecemlineatus 37.04 4.00e-50 191.00
IUUC-Lch-050550 Latimeria chalumnae 40.96 1.00e-53 203.00
IUUC-Loc-052158 Lepisosteus oculatus 40.00 2.00e-55 210.00
IUUC-Lma-053251 Leptosphaeria maculans 24.15 4.00e-15 74.30
IUUC-Laf-054138 Loxodonta africana 38.34 4.00e-54 205.00
IUUC-Mcc-055712 Macaca mulatta 38.34 5.00e-54 205.00
IUUC-Meu-056110 Macropus eugenii 37.05 8.00e-40 156.00
IUUC-Mla-058828 Melampsora laricipopulina 27.01 7.00e-17 80.10
IUUC-Mga-059369 Meleagris gallopavo 35.69 4.00e-50 192.00
IUUC-Mvi-060216 Microbotryum violaceum 27.31 2.00e-17 81.60
IUUC-Mmr-060725 Microcebus murinus 38.34 1.00e-53 203.00
IUUC-Mdo-062533 Monodelphis domestica 38.06 1.00e-47 183.00
IUUC-Mmu-063567 Mus musculus 40.51 1.00e-54 206.00
IUUC-Mpu-066178 Mustela putorius furo 37.23 2.00e-48 186.00
IUUC-Mlu-068015 Myotis lucifugus 39.35 5.00e-47 181.00
IUUC-Ncr-068637 Neurospora crassa 25.00 3.00e-14 71.20
IUUC-Nle-069053 Nomascus leucogenys 38.34 3.00e-54 205.00
IUUC-Opr-070200 Ochotona princeps 43.18 1.00e-27 117.00
IUUC-Ont-072062 Oreochromis niloticus 40.51 2.00e-47 183.00
IUUC-Oan-073435 Ornithorhynchus anatinus 39.13 3.00e-55 209.00
IUUC-Ocu-073813 Oryctolagus cuniculus 37.23 3.00e-48 186.00
IUUC-Olo-080488 Oryza longistaminata 54.17 6.50e-01 26.60
IUUC-Ola-086563 Oryzias latipes 37.83 9.00e-45 174.00
IUUC-Oga-088339 Otolemur garnettii 38.43 3.00e-53 202.00
IUUC-Oar-090177 Ovis aries 39.75 6.00e-52 198.00
IUUC-Ptr-091411 Pan troglodytes 38.34 3.00e-54 205.00
IUUC-Pan-091792 Papio anubis 38.34 5.00e-54 205.00
IUUC-Psi-093226 Pelodiscus sinensis 34.15 2.00e-40 160.00
IUUC-Pma-094171 Petromyzon marinus 38.46 3.00e-51 196.00
IUUC-Pno-094918 Phaeosphaeria nodorum 24.15 3.00e-15 74.70
IUUC-Pfo-096147 Poecilia formosa 40.83 3.00e-48 185.00
IUUC-Pab-098558 Pongo abelii 38.34 3.00e-54 206.00
IUUC-Pca-100306 Procavia capensis 43.94 4.00e-28 118.00
IUUC-Pva-103041 Pteropus vampyrus 37.25 1.00e-46 180.00
IUUC-Ptt-103759 Puccinia triticina 23.77 2.00e-09 55.10
IUUC-Pte-104041 Pyrenophora teres 24.15 4.00e-15 74.30
IUUC-Rno-105656 Rattus norvegicus 40.08 8.00e-54 204.00
IUUC-Sha-106518 Sarcophilus harrisii 37.23 6.00e-49 187.00
IUUC-Spo-108153 Schizosaccharomyces pombe 27.21 7.00e-16 76.60
IUUC-Ssl-108407 Sclerotinia sclerotiorum 26.67 2.00e-16 78.60
IUUC-Sar-113003 Sorex araneus 37.39 1.00e-45 176.00
IUUC-Ssc-115617 Sus scrofa 37.39 9.00e-49 187.00
IUUC-Tgu-117450 Taeniopygia guttata 39.92 4.00e-55 208.00
IUUC-Tru-118595 Takifugu rubripes 40.08 2.00e-49 188.00
IUUC-Tsy-119402 Tarsius syrichta 42.64 6.00e-48 185.00
IUUC-Tni-120824 Tetraodon nigroviridis 39.66 3.00e-49 189.00
IUUC-Tre-121889 Trichoderma reesei 26.67 2.00e-17 81.60
IUUC-Tbe-127836 Tupaia belangeri 41.95 1.00e-42 166.00
IUUC-Ttr-129272 Tursiops truncatus 38.34 3.00e-54 206.00
IUUC-Vpa-130758 Vicugna pacos 37.39 1.00e-48 187.00
IUUC-Xtr-132779 Xenopus tropicalis 39.34 8.00e-43 167.00
IUUC-Xma-134086 Xiphophorus maculatus 41.20 1.00e-47 182.00
IUUC-Yli-134343 Yarrowia lipolytica 22.12 1.00e-11 62.80
Created Date 25-Jun-2017

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