iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007914

Ensembl Protein ID

AAS53256

UniProt Accession

Q755E1; Q755E1_ASHGO

Genbank Protein ID

AAS53256.1

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

AE016819

Gene Name

AGOS_AFL118W

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_AFL118W	AAS53256	AAS53256

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-26	89.9	188	221
UBD/Beta-Prp	1.60e-76	255.3	11	304

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 7    tclaf...sd.tllvsGsdDgtikvWDlrtgvll 36
           + +++   +d ++l+++sdD t+kvWD+ t  ++
   Q: 188  NFVDYypfQDkPYLITSSDDRTVKVWDYQTKSCV 221
           44444788888****************9998886 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdk 108
           +++++++ ++f+p++++++ + ++g+ ++w+++t++ +rs+s +ea+v+a kf+p++++++ gs+D  i+v++++tg+ v+ +++h d++++l+++p++++
   Q: 11   SRTDRVKGIDFHPSEPWVLITLYSGRAEIWNYETQTEVRSISVCEAPVRAGKFIPRKSWIIVGSDDFKIRVFNYNTGEKVVDFEAHPDYIRALAVHPTRSY 111
           678999*********************************************************************************************** PP
   S: 109  lvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvkl 206
           ++s+s+d t+++w++e+++ le+t++gh+++v++v+++p++ n +++++lD tv++W+l +++   tl+   ++ v+ +++ + +  ++l++ s+d+tvk+
   Q: 112  VLSASDDLTVKLWNWEKNWALEQTFEGHEHFVMSVTFNPKDpNTFATACLDHTVKIWSLGQETSNFTLRAHLEKGVNFVDYYPFQdkPYLITSSDDRTVKV 212
           **********************************************************************9999******65544449************* PP
   S: 207  wdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkkne 298
           wd+qt++cv tl+gh +nv+    +p   +++sgs+Dg+++iW++ + +l +tl+l  +++++va++  g+++++++++d+ + +++  ++e
   Q: 213  WDYQTKSCVATLEGHLSNVSYAVYHPMLPIIISGSEDGTVKIWNSNTYKLERTLNLGLERSWCVAAHPTGKRNFIAAGFDNGFTVLAIGNDE 304
           ******************************************************************9999***************9988876 PP

Organism

Ashbya gossypii

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MKLETKKTFV SRTDRVKGID FHPSEPWVLI TLYSGRAEIW NYETQTEVRS ISVCEAPVRA 60
GKFIPRKSWI IVGSDDFKIR VFNYNTGEKV VDFEAHPDYI RALAVHPTRS YVLSASDDLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGTTGG AAACGAAGGT ATGTGTGTGT GCGAGGACGA ATGGGGGCTG CATGGTCGCG 60
CACGGGCTAT TACGGTGTGT TTGAAGACCA TCTTTGCCAC CCACGGAGGG GGCGGAGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0005829--C:cytosol
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0032511--P:late endosome to vacuole transport via multivesicular body sorting pathway
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

ago:AGOS_AFL118W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	39.83	2.00e-166	577.00
IUUC-Aml-002154	Ailuropoda melanoleuca	46.07	0.00e+00	756.00
IUUC-Atr-003090	Amborella trichopoda	48.49	0.00e+00	725.00
IUUC-Apl-003976	Anas platyrhynchos	46.44	0.00e+00	759.00
IUUC-Aca-004301	Anolis carolinensis	46.07	0.00e+00	758.00
IUUC-Aly-005643	Arabidopsis lyrata	46.51	0.00e+00	699.00
IUUC-Ath-007630	Arabidopsis thaliana	47.17	0.00e+00	714.00
IUUC-Acl-008237	Aspergillus clavatus	50.18	0.00e+00	838.00
IUUC-Afl-008535	Aspergillus flavus	51.23	0.00e+00	808.00
IUUC-Afu-008845	Aspergillus fumigatus	49.82	0.00e+00	814.00
IUUC-Ani-009135	Aspergillus nidulans	49.82	0.00e+00	810.00
IUUC-Ang-009654	Aspergillus niger	53.46	0.00e+00	762.00
IUUC-Aor-009939	Aspergillus oryzae	51.09	0.00e+00	863.00
IUUC-Ate-010355	Aspergillus terreus	50.42	0.00e+00	827.00
IUUC-Ame-010922	Astyanax mexicanus	41.64	0.00e+00	641.00
IUUC-Bgr-012249	Blumeria graminis	50.67	0.00e+00	822.00
IUUC-Bta-013579	Bos taurus	47.20	0.00e+00	702.00
IUUC-Bci-013866	Botrytis cinerea	51.14	0.00e+00	799.00
IUUC-Bdi-015046	Brachypodium distachyon	45.79	0.00e+00	714.00
IUUC-Bol-015466	Brassica oleracea	46.29	0.00e+00	706.00
IUUC-Bra-016617	Brassica rapa	46.29	0.00e+00	704.00
IUUC-Cel-018387	Caenorhabditis elegans	44.46	0.00e+00	716.00
IUUC-Cja-019145	Callithrix jacchus	46.07	0.00e+00	757.00
IUUC-Cfa-020564	Canis familiaris	46.07	0.00e+00	756.00
IUUC-Cpo-022201	Cavia porcellus	46.07	0.00e+00	758.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	45.73	0.00e+00	671.00
IUUC-Csa-023383	Chlorocebus sabaeus	48.45	1.00e-177	614.00
IUUC-Cho-024454	Choloepus hoffmanni	43.16	0.00e+00	668.00
IUUC-Cin-025681	Ciona intestinalis	45.51	0.00e+00	705.00
IUUC-Csv-026012	Ciona savignyi	44.50	0.00e+00	694.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	47.20	0.00e+00	713.00
IUUC-Cne-026986	Cryptococcus neoformans	47.98	0.00e+00	782.00
IUUC-Cme-027219	Cyanidioschyzon merolae	39.53	0.00e+00	638.00
IUUC-Dre-027846	Danio rerio	46.45	0.00e+00	758.00
IUUC-Dor-030462	Dipodomys ordii	43.44	6.00e-173	598.00
IUUC-Dse-031268	Dothistroma septosporum	49.94	0.00e+00	830.00
IUUC-Dme-031791	Drosophila melanogaster	45.66	0.00e+00	719.00
IUUC-Ete-033166	Echinops telfairi	43.63	9.00e-145	505.00
IUUC-Eca-034180	Equus caballus	44.89	0.00e+00	721.00
IUUC-Eeu-035086	Erinaceus europaeus	45.78	7.00e-69	253.00
IUUC-Fca-036265	Felis catus	46.07	0.00e+00	756.00
IUUC-Fal-037202	Ficedula albicollis	46.25	0.00e+00	723.00
IUUC-Fox-037711	Fusarium oxysporum	50.00	0.00e+00	757.00
IUUC-Fso-038268	Fusarium solani	49.34	0.00e+00	765.00
IUUC-Gmo-039046	Gadus morhua	46.43	0.00e+00	746.00
IUUC-Ggr-039863	Gaeumannomyces graminis	49.63	0.00e+00	773.00
IUUC-Gga-041112	Gallus gallus	46.32	0.00e+00	759.00
IUUC-Gac-041733	Gasterosteus aculeatus	45.86	0.00e+00	735.00
IUUC-Gma-044333	Glycine max	47.11	0.00e+00	726.00
IUUC-Ggo-044984	Gorilla gorilla	46.07	0.00e+00	756.00
IUUC-Hsa-046698	Homo sapiens	46.07	0.00e+00	756.00
IUUC-Hvu-047669	Hordeum vulgare	55.31	3.00e-117	412.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	46.07	0.00e+00	756.00
IUUC-Kpa-049265	Komagataella pastoris	54.95	0.00e+00	930.00
IUUC-Lch-050473	Latimeria chalumnae	46.42	0.00e+00	760.00
IUUC-Lpe-051579	Leersia perrieri	46.13	0.00e+00	720.00
IUUC-Loc-052675	Lepisosteus oculatus	46.44	0.00e+00	760.00
IUUC-Lma-053218	Leptosphaeria maculans	51.43	0.00e+00	808.00
IUUC-Laf-053757	Loxodonta africana	45.95	0.00e+00	751.00
IUUC-Mcc-054859	Macaca mulatta	46.07	0.00e+00	756.00
IUUC-Meu-056174	Macropus eugenii	39.57	4.00e-59	221.00
IUUC-Mor-057264	Magnaporthe oryzae	49.64	0.00e+00	768.00
IUUC-Mpo-057538	Magnaporthe poae	50.43	0.00e+00	788.00
IUUC-Mtr-058310	Medicago truncatula	46.98	0.00e+00	726.00
IUUC-Mla-058937	Melampsora laricipopulina	49.69	0.00e+00	795.00
IUUC-Mga-059875	Meleagris gallopavo	46.20	0.00e+00	755.00
IUUC-Mvi-060240	Microbotryum violaceum	48.03	0.00e+00	776.00
IUUC-Mmr-061261	Microcebus murinus	46.07	0.00e+00	756.00
IUUC-Mdo-062076	Monodelphis domestica	46.19	0.00e+00	758.00
IUUC-Mmu-063324	Mus musculus	46.19	0.00e+00	758.00
IUUC-Mac-064636	Musa acuminata	46.44	0.00e+00	704.00
IUUC-Mpu-065961	Mustela putorius furo	46.07	0.00e+00	756.00
IUUC-Mlu-067059	Myotis lucifugus	45.82	0.00e+00	737.00
IUUC-Nfi-068277	Neosartorya fischeri	50.00	0.00e+00	812.00
IUUC-Ncr-068659	Neurospora crassa	50.61	0.00e+00	820.00
IUUC-Nle-069034	Nomascus leucogenys	46.07	0.00e+00	756.00
IUUC-Opr-070334	Ochotona princeps	47.28	0.00e+00	726.00
IUUC-Ont-072111	Oreochromis niloticus	45.69	0.00e+00	757.00
IUUC-Oan-073416	Ornithorhynchus anatinus	46.42	0.00e+00	720.00
IUUC-Ocu-074522	Oryctolagus cuniculus	46.07	0.00e+00	755.00
IUUC-Oba-075751	Oryza barthii	44.68	0.00e+00	690.00
IUUC-Obr-076163	Oryza brachyantha	46.57	0.00e+00	722.00
IUUC-Ogl-077450	Oryza glaberrima	46.61	0.00e+00	714.00
IUUC-Ogu-078994	Oryza glumaepatula	45.98	0.00e+00	689.00
IUUC-Oin-079856	Oryza indica	47.28	0.00e+00	720.00
IUUC-Olo-080731	Oryza longistaminata	46.55	0.00e+00	677.00
IUUC-Ome-081554	Oryza meridionalis	43.44	0.00e+00	657.00
IUUC-Oni-082324	Oryza nivara	45.98	0.00e+00	689.00
IUUC-Opu-083400	Oryza punctata	45.49	0.00e+00	706.00
IUUC-Oru-085196	Oryza rufipogon	45.95	0.00e+00	701.00
IUUC-Osa-086026	Oryza sativa	46.73	0.00e+00	716.00
IUUC-Ola-087245	Oryzias latipes	46.18	0.00e+00	753.00
IUUC-Olu-087655	Ostreococcus lucimarinus	44.14	0.00e+00	716.00
IUUC-Oga-088163	Otolemur garnettii	45.06	0.00e+00	722.00
IUUC-Oar-089842	Ovis aries	46.19	0.00e+00	758.00
IUUC-Ptr-090501	Pan troglodytes	46.07	0.00e+00	756.00
IUUC-Pan-092011	Papio anubis	46.07	0.00e+00	756.00
IUUC-Psi-093308	Pelodiscus sinensis	46.19	0.00e+00	758.00
IUUC-Pma-094695	Petromyzon marinus	45.77	0.00e+00	697.00
IUUC-Pno-094785	Phaeosphaeria nodorum	57.89	7.00e-100	355.00
IUUC-Ppa-095638	Physcomitrella patens	46.92	0.00e+00	723.00
IUUC-Pfo-096587	Poecilia formosa	46.49	0.00e+00	755.00
IUUC-Pab-097926	Pongo abelii	44.46	0.00e+00	706.00
IUUC-Pop-099634	Populus trichocarpa	47.36	0.00e+00	730.00
IUUC-Pca-100965	Procavia capensis	45.32	0.00e+00	727.00
IUUC-Ppe-101470	Prunus persica	46.48	0.00e+00	716.00
IUUC-Pva-102451	Pteropus vampyrus	44.04	1.00e-173	601.00
IUUC-Pgr-103590	Puccinia graminis	47.97	0.00e+00	779.00
IUUC-Ptt-103868	Puccinia triticina	48.28	0.00e+00	778.00
IUUC-Pte-104274	Pyrenophora teres	51.80	0.00e+00	832.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	51.55	0.00e+00	784.00
IUUC-Rno-105979	Rattus norvegicus	40.05	4.00e-162	562.00
IUUC-Sce-106269	Saccharomyces cerevisiae	69.28	0.00e+00	1211.00
IUUC-Sha-106905	Sarcophilus harrisii	46.19	0.00e+00	757.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	46.29	0.00e+00	723.00
IUUC-Spo-108299	Schizosaccharomyces pombe	45.74	0.00e+00	753.00
IUUC-Smo-108695	Selaginella moellendorffii	45.63	0.00e+00	681.00
IUUC-Sit-110692	Setaria italica	46.37	0.00e+00	707.00
IUUC-Sly-111775	Solanum lycopersicum	46.12	0.00e+00	714.00
IUUC-Stu-112906	Solanum tuberosum	46.07	0.00e+00	640.00
IUUC-Sar-113472	Sorex araneus	43.69	2.00e-156	543.00
IUUC-Sbi-114052	Sorghum bicolor	46.36	0.00e+00	723.00
IUUC-Sre-115040	Sporisorium reilianum	48.39	0.00e+00	766.00
IUUC-Ssc-115593	Sus scrofa	46.07	0.00e+00	756.00
IUUC-Tgu-117239	Taeniopygia guttata	46.32	0.00e+00	759.00
IUUC-Tru-118025	Takifugu rubripes	46.18	0.00e+00	750.00
IUUC-Tsy-118824	Tarsius syrichta	43.41	1.00e-163	567.00
IUUC-Tni-120142	Tetraodon nigroviridis	46.24	0.00e+00	748.00
IUUC-Tca-121613	Theobroma cacao	46.48	0.00e+00	721.00
IUUC-Tre-122072	Trichoderma reesei	51.35	0.00e+00	821.00
IUUC-Tvi-122546	Trichoderma virens	50.91	0.00e+00	828.00
IUUC-Tae-125488	Triticum aestivum	46.86	0.00e+00	715.00
IUUC-Tur-126283	Triticum urartu	40.41	4.00e-166	576.00
IUUC-Tme-127041	Tuber melanosporum	51.07	0.00e+00	837.00
IUUC-Tbe-127770	Tupaia belangeri	45.55	0.00e+00	634.00
IUUC-Ttr-129294	Tursiops truncatus	46.07	0.00e+00	753.00
IUUC-Uma-129351	Ustilago maydis	46.28	0.00e+00	757.00
IUUC-Vda-129716	Verticillium dahliae	51.07	0.00e+00	844.00
IUUC-Vpa-130037	Vicugna pacos	37.91	3.00e-77	281.00
IUUC-Vvi-131689	Vitis vinifera	47.36	0.00e+00	724.00
IUUC-Xtr-132633	Xenopus tropicalis	46.24	0.00e+00	753.00
IUUC-Xma-133347	Xiphophorus maculatus	46.62	0.00e+00	756.00
IUUC-Yli-134455	Yarrowia lipolytica	52.22	0.00e+00	840.00
IUUC-Zma-135867	Zea mays	46.05	0.00e+00	718.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence