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Tag Content
iUUCD ID IUUC-Mtr-058310
Ensembl Protein ID KEH28771
UniProt Accession A0A072UH84; A0A072UH84_MEDTR
Genbank Protein ID KEH28771.1
Protein Name Coatomer subunit beta'
Genbank Nucleotide ID CM001220
Gene Name MTR_4g011950
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
MTR_4g011950 KEH28771 KEH28771
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.30e-35 120.5 184 224
UBD/Beta-Prp 1.70e-66 225.9 14 290
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+ +v+c+++    d ++l++GsdD+t kvWD+ t  ++++
   Q: 184  HQKGVNCVDYftgGDkPYLITGSDDHTAKVWDYQTKSCVQT 224
           999*****966*9778*******************999986 PP
   

   UBD/Beta-Prp
   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdkl 109
           +++++++v+ +p +++++++ ++gt+ +w+++++++ +s++  e +v++ kf+ ++++ v g++D++i+v++++t + v ++++h+d++++++++p+  ++
   Q: 14   RSERVKSVDLHPTEPWILASLYSGTVCIWNYQSQTMAKSFEVTELPVRSAKFIARKQWVVAGADDMFIRVYNYNTMDKVKVFEAHSDYIRCVAVHPTLPYV 114
           5678999********************************************************************************************** PP
   S: 110  vsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls..fdsngkelvsgsldgtvklw 207
           +s s+d  i++wd+e+g+   ++++gh++ v+ v+++p++ n ++s+slDrt+++W+l + +   tl   h++ v++++     ++++l++gs+d t k+w
   Q: 115  LSSSDDMLIKLWDWEKGWICTQIFEGHSHYVMQVTFNPKDtNTFASASLDRTIKIWNLGSPDPNFTLDA-HQKGVNCVDyfTGGDKPYLITGSDDHTAKVW 214
           ******************9999*********************************************98.*********6444555*************** PP
   S: 208  dlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlg 283
           d+qt++cv+tl ght nv+ v f+p+  ++++gs+Dg++riW +++  l +tl++  ++v+++ +++ +++v++  
   Q: 215  DYQTKSCVQTLDGHTHNVSAVCFHPELPIIITGSEDGTVRIWHSTTYRLENTLNYGLERVWAIGYMKGSRRVVIGY 290
           ***************************************************************9966666666433 PP
   
Organism Medicago truncatula
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Protein Sequence
(Fasta)
MPLRLEIKRK LAQRSERVKS VDLHPTEPWI LASLYSGTVC IWNYQSQTMA KSFEVTELPV 60
RSAKFIARKQ WVVAGADDMF IRVYNYNTMD KVKVFEAHSD YIRCVAVHPT LPYVLSSSDD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mtr-058310|E3,WD_repeat;UBD,Beta-Prp|Medicago truncatula
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCCTTGTGAA CCAAACACAC TTTTAATTAA AAATATCTCC CCTCCACTCC CCTCCGTAAA 60
AATCCCTCCC CTCCCCTCCT AATTCTCGAA CCAAACGGAT CGAGAGTGTG ATGACTCACT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mtr-058310|E3,WD_repeat;UBD,Beta-Prp|Medicago truncatula
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04053--Coatomer_WDAD
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport
KEGG mtr:MTR_4g011950
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002154 Ailuropoda melanoleuca 62.67 0.00e+00 1125.00
IUUC-Apl-003976 Anas platyrhynchos 62.42 0.00e+00 1127.00
IUUC-Aca-004301 Anolis carolinensis 62.47 0.00e+00 1129.00
IUUC-Ago-007914 Ashbya gossypii 46.98 0.00e+00 726.00
IUUC-Acl-008237 Aspergillus clavatus 52.67 0.00e+00 906.00
IUUC-Afl-008535 Aspergillus flavus 53.34 0.00e+00 861.00
IUUC-Afu-008845 Aspergillus fumigatus 52.86 0.00e+00 895.00
IUUC-Ani-009135 Aspergillus nidulans 54.28 0.00e+00 886.00
IUUC-Ang-009654 Aspergillus niger 56.97 0.00e+00 819.00
IUUC-Aor-009939 Aspergillus oryzae 52.36 0.00e+00 920.00
IUUC-Ate-010355 Aspergillus terreus 52.43 0.00e+00 883.00
IUUC-Ame-010922 Astyanax mexicanus 56.82 0.00e+00 981.00
IUUC-Bgr-012249 Blumeria graminis 52.83 0.00e+00 899.00
IUUC-Bta-013579 Bos taurus 62.38 0.00e+00 979.00
IUUC-Bci-013866 Botrytis cinerea 53.12 0.00e+00 899.00
IUUC-Cel-018387 Caenorhabditis elegans 53.83 0.00e+00 982.00
IUUC-Cja-019145 Callithrix jacchus 62.59 0.00e+00 1126.00
IUUC-Cfa-020564 Canis familiaris 62.71 0.00e+00 1129.00
IUUC-Cpo-022201 Cavia porcellus 62.67 0.00e+00 1125.00
IUUC-Csa-023383 Chlorocebus sabaeus 65.61 0.00e+00 838.00
IUUC-Cho-024454 Choloepus hoffmanni 59.16 0.00e+00 934.00
IUUC-Cin-025681 Ciona intestinalis 59.08 0.00e+00 997.00
IUUC-Csv-026012 Ciona savignyi 58.35 0.00e+00 974.00
IUUC-Cgl-026649 Colletotrichum gloeosporioides 49.14 0.00e+00 806.00
IUUC-Cne-026986 Cryptococcus neoformans 50.00 0.00e+00 872.00
IUUC-Cme-027219 Cyanidioschyzon merolae 49.94 0.00e+00 890.00
IUUC-Dre-027846 Danio rerio 62.76 0.00e+00 1131.00
IUUC-Dor-030462 Dipodomys ordii 59.82 0.00e+00 862.00
IUUC-Dse-031268 Dothistroma septosporum 52.62 0.00e+00 890.00
IUUC-Dme-031791 Drosophila melanogaster 57.48 0.00e+00 1015.00
IUUC-Ete-033166 Echinops telfairi 58.39 0.00e+00 707.00
IUUC-Eca-034180 Equus caballus 61.14 0.00e+00 1082.00
IUUC-Eeu-035086 Erinaceus europaeus 51.74 2.00e-128 453.00
IUUC-Fca-036265 Felis catus 62.71 0.00e+00 1127.00
IUUC-Fal-037202 Ficedula albicollis 61.86 0.00e+00 1078.00
IUUC-Fox-037711 Fusarium oxysporum 53.86 0.00e+00 863.00
IUUC-Fso-038268 Fusarium solani 53.22 0.00e+00 870.00
IUUC-Gmo-039046 Gadus morhua 62.03 0.00e+00 1115.00
IUUC-Ggr-039863 Gaeumannomyces graminis 52.70 0.00e+00 884.00
IUUC-Gga-041112 Gallus gallus 63.08 0.00e+00 1134.00
IUUC-Gac-041733 Gasterosteus aculeatus 61.67 0.00e+00 1086.00
IUUC-Gma-042910 Glycine max 93.06 0.00e+00 1760.00
IUUC-Ggo-044984 Gorilla gorilla 62.59 0.00e+00 1127.00
IUUC-Hsa-046698 Homo sapiens 62.47 0.00e+00 1127.00
IUUC-Hvu-047669 Hordeum vulgare 90.68 0.00e+00 699.00
IUUC-Itr-048212 Ictidomys tridecemlineatus 62.67 0.00e+00 1123.00
IUUC-Kpa-049265 Komagataella pastoris 51.02 0.00e+00 843.00
IUUC-Lch-050473 Latimeria chalumnae 62.76 0.00e+00 1129.00
IUUC-Loc-052675 Lepisosteus oculatus 61.66 0.00e+00 1133.00
IUUC-Lma-053218 Leptosphaeria maculans 51.95 0.00e+00 868.00
IUUC-Laf-053757 Loxodonta africana 62.64 0.00e+00 1123.00
IUUC-Mcc-054859 Macaca mulatta 62.59 0.00e+00 1126.00
IUUC-Meu-056174 Macropus eugenii 55.74 6.00e-114 404.00
IUUC-Mor-057264 Magnaporthe oryzae 53.19 0.00e+00 873.00
IUUC-Mpo-057538 Magnaporthe poae 52.45 0.00e+00 888.00
IUUC-Mla-058937 Melampsora laricipopulina 53.28 0.00e+00 900.00
IUUC-Mga-059875 Meleagris gallopavo 62.80 0.00e+00 1130.00
IUUC-Mvi-060240 Microbotryum violaceum 50.45 0.00e+00 905.00
IUUC-Mmr-061261 Microcebus murinus 62.71 0.00e+00 1128.00
IUUC-Mdo-062076 Monodelphis domestica 62.95 0.00e+00 1135.00
IUUC-Mmu-063324 Mus musculus 62.59 0.00e+00 1128.00
IUUC-Mpu-065961 Mustela putorius furo 62.71 0.00e+00 1127.00
IUUC-Mlu-067059 Myotis lucifugus 61.99 0.00e+00 1108.00
IUUC-Nfi-068277 Neosartorya fischeri 52.69 0.00e+00 884.00
IUUC-Ncr-068659 Neurospora crassa 53.18 0.00e+00 904.00
IUUC-Nle-069034 Nomascus leucogenys 62.59 0.00e+00 1127.00
IUUC-Opr-070334 Ochotona princeps 63.23 0.00e+00 1016.00
IUUC-Ont-071563 Oreochromis niloticus 62.39 0.00e+00 1123.00
IUUC-Oan-073416 Ornithorhynchus anatinus 61.98 0.00e+00 1068.00
IUUC-Ocu-074522 Oryctolagus cuniculus 62.71 0.00e+00 1124.00
IUUC-Ola-087245 Oryzias latipes 62.11 0.00e+00 1121.00
IUUC-Oga-088163 Otolemur garnettii 60.29 0.00e+00 1068.00
IUUC-Oar-089842 Ovis aries 62.71 0.00e+00 1128.00
IUUC-Ptr-090501 Pan troglodytes 62.59 0.00e+00 1127.00
IUUC-Pan-092011 Papio anubis 62.59 0.00e+00 1127.00
IUUC-Psi-093308 Pelodiscus sinensis 62.95 0.00e+00 1132.00
IUUC-Pma-094695 Petromyzon marinus 59.07 0.00e+00 988.00
IUUC-Pno-094785 Phaeosphaeria nodorum 58.08 2.00e-103 369.00
IUUC-Pfo-096587 Poecilia formosa 62.27 0.00e+00 1125.00
IUUC-Pab-097926 Pongo abelii 60.86 0.00e+00 1054.00
IUUC-Pca-100965 Procavia capensis 61.82 0.00e+00 1092.00
IUUC-Pva-102451 Pteropus vampyrus 58.77 0.00e+00 855.00
IUUC-Pgr-103453 Puccinia graminis 53.11 0.00e+00 901.00
IUUC-Ptt-103868 Puccinia triticina 53.06 0.00e+00 899.00
IUUC-Pte-104274 Pyrenophora teres 53.11 0.00e+00 899.00
IUUC-Pyt-104794 Pyrenophora triticirepentis 52.28 0.00e+00 846.00
IUUC-Rno-105979 Rattus norvegicus 53.58 0.00e+00 827.00
IUUC-Sce-106269 Saccharomyces cerevisiae 47.68 0.00e+00 760.00
IUUC-Sha-106905 Sarcophilus harrisii 62.83 0.00e+00 1132.00
IUUC-Sja-107838 Schizosaccharomyces japonicus 46.65 0.00e+00 777.00
IUUC-Spo-108299 Schizosaccharomyces pombe 46.72 0.00e+00 804.00
IUUC-Smo-108828 Selaginella moellendorffii 80.76 0.00e+00 1408.00
IUUC-Sar-113472 Sorex araneus 57.42 0.00e+00 768.00
IUUC-Sre-115040 Sporisorium reilianum 53.46 0.00e+00 908.00
IUUC-Ssc-115593 Sus scrofa 62.59 0.00e+00 1127.00
IUUC-Tgu-117239 Taeniopygia guttata 62.67 0.00e+00 1130.00
IUUC-Tru-118025 Takifugu rubripes 62.08 0.00e+00 1121.00
IUUC-Tsy-118824 Tarsius syrichta 58.57 0.00e+00 798.00
IUUC-Tni-120142 Tetraodon nigroviridis 61.99 0.00e+00 1115.00
IUUC-Tre-122072 Trichoderma reesei 52.70 0.00e+00 896.00
IUUC-Tvi-122546 Trichoderma virens 51.84 0.00e+00 872.00
IUUC-Tme-127041 Tuber melanosporum 52.82 0.00e+00 908.00
IUUC-Tbe-127770 Tupaia belangeri 61.35 0.00e+00 900.00
IUUC-Ttr-129294 Tursiops truncatus 62.47 0.00e+00 1125.00
IUUC-Uma-129351 Ustilago maydis 51.64 0.00e+00 892.00
IUUC-Vda-129716 Verticillium dahliae 52.63 0.00e+00 904.00
IUUC-Vpa-130037 Vicugna pacos 52.05 2.00e-132 466.00
IUUC-Xtr-132633 Xenopus tropicalis 62.35 0.00e+00 1124.00
IUUC-Xma-133347 Xiphophorus maculatus 62.52 0.00e+00 1127.00
IUUC-Yli-134455 Yarrowia lipolytica 50.63 0.00e+00 816.00
Created Date 25-Jun-2017

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