iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-087245

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

BAAF04030392

Gene Name

copb2; LOC101157089

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000014074.1	ENSORLT00000017647.1	ENSORLP00000017646.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-33	113.8	182	223
UBD/Beta-Prp	7.40e-73	245.6	12	289

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD ++k+WD+   +++++
   Q: 182  GHEKGVNCIDYysgGDkPYLISGADDRQVKIWDYQNKTCVQT 223
           8*********9999778****************999988875 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++++++++v+ +p +++++++ ++g++ vw+ +t++l+++++ ++ +v+a kf  ++++ +tg++D+ i+v++++t + vh +++h+d+
   Q: 12   ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRASKFVARKNWVITGADDMQIRVFNYNTLERVHMFEAHSDY 100
           678999*********************************************************************************** PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +++++++p++ ++++ s+d  i++wd+++++  +++++gh++ v+ +v++p++ n ++s+slDrt+++W+l + +   tl+g h++ v+
   Q: 101  IRCIAVHPTQPYILTSSDDMLIKLWDWDKKWTCSQVFEGHTHYVMQIVINPKDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVN 188
           ******************************99999**********************************************9.****** PP
   S: 185  slsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           ++++ s g  ++l+sg++d++vk+wd+q+++cv+tl+gh +nv++v f+p+  ++++gs+Dg++riW + +  l +tl++  ++v++v+
   Q: 189  CIDYYSGGdkPYLISGADDRQVKIWDYQNKTCVQTLEGHAQNVSCVSFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVC 277
           ***8887777******************************************************************************* PP
   S: 272  vlsfgdnvlvlg 283
           +l+ ++nv +  
   Q: 278  GLRGSNNVALGY 289
           *99999887544 PP

Organism

Oryzias latipes

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

PLRLDIKRRL TARSDRVKSV DLHPTEPWML ASLYNGSVCV WNHETQTLVK TFEVCDLPVR 60
ASKFVARKNW VITGADDMQI RVFNYNTLER VHMFEAHSDY IRCIAVHPTQ PYILTSSDDM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCTGAGGC TGGACATTAA ACGGAGGCTT ACTGCCAGAT CAGACCGTGT GAAGAGTGTG 60
GATCTTCATC CAACTGAGCC ATGGATGCTA GCTAGTCTGT ACAACGGCAG CGTCTGTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0030903--P:notochord development
GO:0061053--P:somite development
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	52.98	0.00e+00	931.00
IUUC-Aml-002154	Ailuropoda melanoleuca	87.35	0.00e+00	1671.00
IUUC-Atr-003090	Amborella trichopoda	58.33	0.00e+00	1062.00
IUUC-Apl-003976	Anas platyrhynchos	91.95	0.00e+00	1685.00
IUUC-Aca-004301	Anolis carolinensis	93.25	0.00e+00	1669.00
IUUC-Aly-005643	Arabidopsis lyrata	60.88	0.00e+00	1080.00
IUUC-Ath-007630	Arabidopsis thaliana	61.45	0.00e+00	1100.00
IUUC-Ago-007914	Ashbya gossypii	46.18	0.00e+00	752.00
IUUC-Acl-008237	Aspergillus clavatus	56.51	0.00e+00	962.00
IUUC-Afl-008535	Aspergillus flavus	56.02	0.00e+00	910.00
IUUC-Afu-008845	Aspergillus fumigatus	54.99	0.00e+00	936.00
IUUC-Ani-009135	Aspergillus nidulans	55.95	0.00e+00	912.00
IUUC-Ang-009654	Aspergillus niger	55.75	0.00e+00	853.00
IUUC-Aor-009939	Aspergillus oryzae	53.64	0.00e+00	968.00
IUUC-Ate-010355	Aspergillus terreus	54.16	0.00e+00	914.00
IUUC-Ame-010922	Astyanax mexicanus	86.87	0.00e+00	1555.00
IUUC-Bgr-012249	Blumeria graminis	54.01	0.00e+00	920.00
IUUC-Bta-013579	Bos taurus	95.23	0.00e+00	1439.00
IUUC-Bci-013866	Botrytis cinerea	55.07	0.00e+00	920.00
IUUC-Bdi-015046	Brachypodium distachyon	62.30	0.00e+00	1099.00
IUUC-Bol-016271	Brassica oleracea	61.06	0.00e+00	1102.00
IUUC-Bra-017758	Brassica rapa	61.06	0.00e+00	1103.00
IUUC-Cel-018387	Caenorhabditis elegans	65.21	0.00e+00	1173.00
IUUC-Cja-019145	Callithrix jacchus	88.48	0.00e+00	1674.00
IUUC-Cfa-020564	Canis familiaris	91.15	0.00e+00	1666.00
IUUC-Cpo-022201	Cavia porcellus	91.15	0.00e+00	1668.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	59.06	0.00e+00	984.00
IUUC-Csa-023383	Chlorocebus sabaeus	93.99	0.00e+00	1140.00
IUUC-Cho-024454	Choloepus hoffmanni	88.57	0.00e+00	1362.00
IUUC-Cin-025681	Ciona intestinalis	77.84	0.00e+00	1361.00
IUUC-Csv-026012	Ciona savignyi	72.41	0.00e+00	1339.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	52.24	0.00e+00	837.00
IUUC-Cne-026986	Cryptococcus neoformans	50.54	0.00e+00	902.00
IUUC-Cme-027219	Cyanidioschyzon merolae	47.97	0.00e+00	847.00
IUUC-Dre-027846	Danio rerio	95.52	0.00e+00	1716.00
IUUC-Dor-030462	Dipodomys ordii	89.01	0.00e+00	1233.00
IUUC-Dse-031268	Dothistroma septosporum	54.84	0.00e+00	951.00
IUUC-Dme-031791	Drosophila melanogaster	71.62	0.00e+00	1258.00
IUUC-Ete-033166	Echinops telfairi	84.74	0.00e+00	979.00
IUUC-Eca-034180	Equus caballus	88.75	0.00e+00	1613.00
IUUC-Eeu-035086	Erinaceus europaeus	75.58	0.00e+00	796.00
IUUC-Fca-036265	Felis catus	87.85	0.00e+00	1672.00
IUUC-Fal-037202	Ficedula albicollis	91.30	0.00e+00	1629.00
IUUC-Fox-037711	Fusarium oxysporum	55.79	0.00e+00	875.00
IUUC-Fso-038268	Fusarium solani	55.39	0.00e+00	875.00
IUUC-Gmo-039046	Gadus morhua	96.20	0.00e+00	1713.00
IUUC-Ggr-039863	Gaeumannomyces graminis	54.62	0.00e+00	897.00
IUUC-Gga-041112	Gallus gallus	91.84	0.00e+00	1686.00
IUUC-Gac-041733	Gasterosteus aculeatus	95.18	0.00e+00	1704.00
IUUC-Gma-042910	Glycine max	61.99	0.00e+00	1109.00
IUUC-Ggo-044984	Gorilla gorilla	87.84	0.00e+00	1665.00
IUUC-Hsa-046698	Homo sapiens	87.94	0.00e+00	1666.00
IUUC-Hvu-047669	Hordeum vulgare	70.62	4.00e-168	583.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	92.54	0.00e+00	1670.00
IUUC-Kpa-049265	Komagataella pastoris	49.19	0.00e+00	863.00
IUUC-Lch-050473	Latimeria chalumnae	89.47	0.00e+00	1709.00
IUUC-Lpe-051579	Leersia perrieri	62.09	0.00e+00	1088.00
IUUC-Loc-052675	Lepisosteus oculatus	95.05	0.00e+00	1710.00
IUUC-Lma-053218	Leptosphaeria maculans	54.00	0.00e+00	922.00
IUUC-Laf-053757	Loxodonta africana	88.51	0.00e+00	1665.00
IUUC-Mcc-054859	Macaca mulatta	88.37	0.00e+00	1672.00
IUUC-Meu-056174	Macropus eugenii	90.26	0.00e+00	709.00
IUUC-Mor-057264	Magnaporthe oryzae	54.85	0.00e+00	880.00
IUUC-Mpo-057538	Magnaporthe poae	54.87	0.00e+00	912.00
IUUC-Mtr-058310	Medicago truncatula	62.11	0.00e+00	1119.00
IUUC-Mla-058937	Melampsora laricipopulina	52.96	0.00e+00	899.00
IUUC-Mga-059875	Meleagris gallopavo	91.63	0.00e+00	1679.00
IUUC-Mvi-060240	Microbotryum violaceum	50.56	0.00e+00	905.00
IUUC-Mmr-061261	Microcebus murinus	88.70	0.00e+00	1676.00
IUUC-Mdo-062076	Monodelphis domestica	91.07	0.00e+00	1691.00
IUUC-Mmu-063324	Mus musculus	88.59	0.00e+00	1675.00
IUUC-Mac-064636	Musa acuminata	58.93	0.00e+00	1077.00
IUUC-Mpu-065961	Mustela putorius furo	88.27	0.00e+00	1667.00
IUUC-Mlu-067059	Myotis lucifugus	92.77	0.00e+00	1610.00
IUUC-Nfi-068277	Neosartorya fischeri	54.70	0.00e+00	926.00
IUUC-Ncr-068659	Neurospora crassa	53.07	0.00e+00	912.00
IUUC-Nle-069034	Nomascus leucogenys	88.27	0.00e+00	1672.00
IUUC-Opr-070334	Ochotona princeps	94.69	0.00e+00	1474.00
IUUC-Ont-071563	Oreochromis niloticus	94.74	0.00e+00	1773.00
IUUC-Oan-073416	Ornithorhynchus anatinus	93.52	0.00e+00	1599.00
IUUC-Ocu-074522	Oryctolagus cuniculus	88.37	0.00e+00	1668.00
IUUC-Oba-075760	Oryza barthii	60.69	0.00e+00	1070.00
IUUC-Obr-076163	Oryza brachyantha	62.30	0.00e+00	1093.00
IUUC-Ogl-077450	Oryza glaberrima	61.93	0.00e+00	1097.00
IUUC-Ogu-078994	Oryza glumaepatula	60.69	0.00e+00	1068.00
IUUC-Oin-079856	Oryza indica	60.39	0.00e+00	1073.00
IUUC-Olo-080731	Oryza longistaminata	58.79	0.00e+00	1055.00
IUUC-Ome-081762	Oryza meridionalis	56.99	0.00e+00	991.00
IUUC-Oni-082324	Oryza nivara	60.69	0.00e+00	1069.00
IUUC-Opu-083400	Oryza punctata	59.30	0.00e+00	1059.00
IUUC-Oru-084829	Oryza rufipogon	60.69	0.00e+00	1069.00
IUUC-Osa-086026	Oryza sativa	61.93	0.00e+00	1101.00
IUUC-Olu-087655	Ostreococcus lucimarinus	59.43	0.00e+00	1045.00
IUUC-Oga-088163	Otolemur garnettii	85.39	0.00e+00	1605.00
IUUC-Oar-089842	Ovis aries	91.03	0.00e+00	1667.00
IUUC-Ptr-090501	Pan troglodytes	88.16	0.00e+00	1668.00
IUUC-Pan-092011	Papio anubis	88.37	0.00e+00	1675.00
IUUC-Psi-093308	Pelodiscus sinensis	93.76	0.00e+00	1683.00
IUUC-Pma-094695	Petromyzon marinus	80.52	0.00e+00	1431.00
IUUC-Pno-094785	Phaeosphaeria nodorum	61.38	1.00e-110	393.00
IUUC-Ppa-095911	Physcomitrella patens	61.44	0.00e+00	1122.00
IUUC-Pfo-096587	Poecilia formosa	93.44	0.00e+00	1809.00
IUUC-Pab-097926	Pongo abelii	85.97	0.00e+00	1578.00
IUUC-Pop-099634	Populus trichocarpa	61.62	0.00e+00	1101.00
IUUC-Pca-100965	Procavia capensis	89.43	0.00e+00	1624.00
IUUC-Ppe-101470	Prunus persica	61.74	0.00e+00	1108.00
IUUC-Pva-102451	Pteropus vampyrus	88.10	0.00e+00	1222.00
IUUC-Pgr-103453	Puccinia graminis	52.83	0.00e+00	915.00
IUUC-Ptt-103868	Puccinia triticina	53.18	0.00e+00	912.00
IUUC-Pte-104274	Pyrenophora teres	55.04	0.00e+00	953.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	54.50	0.00e+00	902.00
IUUC-Rno-105979	Rattus norvegicus	80.87	0.00e+00	1221.00
IUUC-Sce-106269	Saccharomyces cerevisiae	46.67	0.00e+00	777.00
IUUC-Sha-106905	Sarcophilus harrisii	92.07	0.00e+00	1688.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	47.09	0.00e+00	825.00
IUUC-Spo-108299	Schizosaccharomyces pombe	46.52	0.00e+00	823.00
IUUC-Smo-108828	Selaginella moellendorffii	61.73	0.00e+00	1076.00
IUUC-Sit-110239	Setaria italica	56.09	0.00e+00	1099.00
IUUC-Sly-111525	Solanum lycopersicum	61.26	0.00e+00	1114.00
IUUC-Stu-112906	Solanum tuberosum	61.44	0.00e+00	988.00
IUUC-Sar-113472	Sorex araneus	87.06	0.00e+00	1117.00
IUUC-Sbi-114052	Sorghum bicolor	62.92	0.00e+00	1115.00
IUUC-Sre-115040	Sporisorium reilianum	51.95	0.00e+00	909.00
IUUC-Ssc-115593	Sus scrofa	88.37	0.00e+00	1673.00
IUUC-Tgu-117239	Taeniopygia guttata	93.97	0.00e+00	1683.00
IUUC-Tru-118025	Takifugu rubripes	96.06	0.00e+00	1739.00
IUUC-Tsy-118824	Tarsius syrichta	86.60	0.00e+00	1125.00
IUUC-Tni-120142	Tetraodon nigroviridis	95.16	0.00e+00	1736.00
IUUC-Tca-121613	Theobroma cacao	61.26	0.00e+00	1103.00
IUUC-Tre-122072	Trichoderma reesei	54.20	0.00e+00	928.00
IUUC-Tvi-122546	Trichoderma virens	54.74	0.00e+00	912.00
IUUC-Tae-125488	Triticum aestivum	61.36	0.00e+00	1090.00
IUUC-Tur-126283	Triticum urartu	53.85	0.00e+00	931.00
IUUC-Tme-127041	Tuber melanosporum	55.64	0.00e+00	970.00
IUUC-Tbe-127770	Tupaia belangeri	88.25	0.00e+00	1230.00
IUUC-Ttr-129294	Tursiops truncatus	88.37	0.00e+00	1671.00
IUUC-Uma-129351	Ustilago maydis	50.73	0.00e+00	899.00
IUUC-Vda-129716	Verticillium dahliae	54.55	0.00e+00	947.00
IUUC-Vpa-130037	Vicugna pacos	77.99	0.00e+00	832.00
IUUC-Vvi-131689	Vitis vinifera	62.21	0.00e+00	1102.00
IUUC-Xtr-132633	Xenopus tropicalis	88.51	0.00e+00	1656.00
IUUC-Xma-133347	Xiphophorus maculatus	94.87	0.00e+00	1818.00
IUUC-Yli-134455	Yarrowia lipolytica	50.64	0.00e+00	841.00
IUUC-Zma-135706	Zea mays	60.40	0.00e+00	1112.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence