iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071563

Ensembl Protein ID

ENSONIP00000013082.1

UniProt Accession

I3JW37; I3JW37_ORENI

Genbank Protein ID

ENSONIP00000013082

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

AERX01001288

Gene Name

copb2; LOC100691498

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000010410.1	ENSONIT00000013092.1	ENSONIP00000013082.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.70e-35	118.2	183	224
UBD/Beta-Prp	2.00e-73	247.6	13	290

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD ++k+WD+   +++++
   Q: 183  GHEKGVNCIDYysgGDkPYLISGADDRQVKIWDYQNKTCVQT 224
           8*********9999778****************999988875 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++++++++v+ +p +++++++ ++g++ vw+ +t++l+++++ ++ +v+a kf  ++++ +tg++D+ i+v++++t + vh +++h+d+
   Q: 13   ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRASKFVARKNWVITGADDMQIRVFNYNTLERVHMFEAHSDY 101
           678999*********************************************************************************** PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +++++++p++ ++++ s+d  i++wd+e+++  +++++gh++ v+ +v++p++ n ++s+slDrt+++W+l + +   tl+g h++ v+
   Q: 102  IRCIAVHPTQPYILTSSDDMLIKLWDWEKKWSCSQVFEGHTHYVMQIVINPKDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVN 189
           *******************************9999**********************************************9.****** PP
   S: 185  slsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           ++++ s g  ++l+sg++d++vk+wd+q+++cv+tl+gh +nv++v f+p+  ++++gs+Dg++riW + +  l +tl++  ++v++v+
   Q: 190  CIDYYSGGdkPYLISGADDRQVKIWDYQNKTCVQTLEGHAQNVSCVSFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVS 278
           ***8887777******************************************************************************* PP
   S: 272  vlsfgdnvlvlg 283
           +l+ ++nv +  
   Q: 279  GLRGSNNVALGY 290
           *99999887544 PP

Organism

Oreochromis niloticus

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLDIKRR LTARSDRVKS VDLHPTEPWM LASLYNGSVC VWNHETQTLV KTFEVCDLPV 60
RASKFVARKN WVITGADDMQ IRVFNYNTLE RVHMFEAHSD YIRCIAVHPT QPYILTSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATTGACTT TGCTACAAGG AAAATTGCCA TCTCCCTATC TCAGACCAAA GTGGTTTTCC 60
AAGATGGGGA CAAGTTTGAC TTCAAAACAC TGAGCACCTT TAGGAATTAT GAGCTGGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0030903--P:notochord development
GO:0061053--P:somite development
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	53.39	0.00e+00	936.00
IUUC-Aml-002154	Ailuropoda melanoleuca	88.47	0.00e+00	1678.00
IUUC-Atr-003090	Amborella trichopoda	58.76	0.00e+00	1072.00
IUUC-Apl-003976	Anas platyrhynchos	94.21	0.00e+00	1688.00
IUUC-Aca-004301	Anolis carolinensis	93.85	0.00e+00	1677.00
IUUC-Aly-006508	Arabidopsis lyrata	60.99	0.00e+00	1092.00
IUUC-Ath-007630	Arabidopsis thaliana	61.74	0.00e+00	1106.00
IUUC-Acl-008237	Aspergillus clavatus	56.51	0.00e+00	962.00
IUUC-Afl-008535	Aspergillus flavus	56.06	0.00e+00	910.00
IUUC-Afu-008845	Aspergillus fumigatus	54.99	0.00e+00	936.00
IUUC-Ani-009135	Aspergillus nidulans	56.35	0.00e+00	915.00
IUUC-Ang-009654	Aspergillus niger	55.75	0.00e+00	854.00
IUUC-Aor-009939	Aspergillus oryzae	53.61	0.00e+00	969.00
IUUC-Ate-010355	Aspergillus terreus	54.25	0.00e+00	912.00
IUUC-Ame-010922	Astyanax mexicanus	87.98	0.00e+00	1556.00
IUUC-Bgr-012249	Blumeria graminis	53.64	0.00e+00	915.00
IUUC-Bta-013579	Bos taurus	95.51	0.00e+00	1442.00
IUUC-Bci-013866	Botrytis cinerea	54.29	0.00e+00	914.00
IUUC-Bdi-015046	Brachypodium distachyon	60.91	0.00e+00	1102.00
IUUC-Bol-016271	Brassica oleracea	61.35	0.00e+00	1108.00
IUUC-Bra-016617	Brassica rapa	61.00	0.00e+00	1075.00
IUUC-Cel-018387	Caenorhabditis elegans	64.66	0.00e+00	1171.00
IUUC-Cja-019145	Callithrix jacchus	88.70	0.00e+00	1681.00
IUUC-Cfa-020564	Canis familiaris	88.91	0.00e+00	1675.00
IUUC-Cpo-022201	Cavia porcellus	93.48	0.00e+00	1668.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	59.44	0.00e+00	991.00
IUUC-Csa-023383	Chlorocebus sabaeus	94.36	0.00e+00	1145.00
IUUC-Cho-024454	Choloepus hoffmanni	88.71	0.00e+00	1364.00
IUUC-Cin-025681	Ciona intestinalis	78.32	0.00e+00	1368.00
IUUC-Csv-026012	Ciona savignyi	77.05	0.00e+00	1343.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	51.87	0.00e+00	833.00
IUUC-Cne-026986	Cryptococcus neoformans	50.85	0.00e+00	905.00
IUUC-Cme-027219	Cyanidioschyzon merolae	47.99	0.00e+00	851.00
IUUC-Dre-027846	Danio rerio	95.33	0.00e+00	1722.00
IUUC-Dor-030462	Dipodomys ordii	89.47	0.00e+00	1239.00
IUUC-Dse-031268	Dothistroma septosporum	55.21	0.00e+00	949.00
IUUC-Dme-031791	Drosophila melanogaster	72.39	0.00e+00	1267.00
IUUC-Ete-033166	Echinops telfairi	84.95	0.00e+00	984.00
IUUC-Eca-034180	Equus caballus	91.48	0.00e+00	1620.00
IUUC-Eeu-035086	Erinaceus europaeus	76.24	0.00e+00	800.00
IUUC-Fca-036265	Felis catus	88.27	0.00e+00	1684.00
IUUC-Fal-037202	Ficedula albicollis	94.25	0.00e+00	1632.00
IUUC-Fox-037711	Fusarium oxysporum	55.27	0.00e+00	875.00
IUUC-Fso-038268	Fusarium solani	55.39	0.00e+00	874.00
IUUC-Gmo-039046	Gadus morhua	96.56	0.00e+00	1721.00
IUUC-Ggr-039863	Gaeumannomyces graminis	54.71	0.00e+00	891.00
IUUC-Gga-041112	Gallus gallus	93.76	0.00e+00	1687.00
IUUC-Gac-041733	Gasterosteus aculeatus	97.08	0.00e+00	1710.00
IUUC-Gma-042910	Glycine max	62.39	0.00e+00	1115.00
IUUC-Ggo-044984	Gorilla gorilla	88.27	0.00e+00	1674.00
IUUC-Hsa-046698	Homo sapiens	88.27	0.00e+00	1675.00
IUUC-Hvu-047669	Hordeum vulgare	70.34	1.00e-167	582.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	93.00	0.00e+00	1674.00
IUUC-Lch-050473	Latimeria chalumnae	89.13	0.00e+00	1706.00
IUUC-Lpe-051579	Leersia perrieri	61.23	0.00e+00	1090.00
IUUC-Loc-052675	Lepisosteus oculatus	95.40	0.00e+00	1711.00
IUUC-Lma-053218	Leptosphaeria maculans	54.59	0.00e+00	918.00
IUUC-Laf-053757	Loxodonta africana	88.39	0.00e+00	1670.00
IUUC-Mcc-054859	Macaca mulatta	88.70	0.00e+00	1680.00
IUUC-Meu-056174	Macropus eugenii	90.79	0.00e+00	711.00
IUUC-Mor-057264	Magnaporthe oryzae	55.23	0.00e+00	881.00
IUUC-Mpo-057538	Magnaporthe poae	54.96	0.00e+00	905.00
IUUC-Mtr-058310	Medicago truncatula	62.39	0.00e+00	1123.00
IUUC-Mla-058937	Melampsora laricipopulina	53.21	0.00e+00	901.00
IUUC-Mga-059875	Meleagris gallopavo	93.76	0.00e+00	1681.00
IUUC-Mvi-060240	Microbotryum violaceum	51.06	0.00e+00	910.00
IUUC-Mmr-061261	Microcebus murinus	88.91	0.00e+00	1680.00
IUUC-Mdo-062076	Monodelphis domestica	91.06	0.00e+00	1689.00
IUUC-Mmu-063324	Mus musculus	88.59	0.00e+00	1680.00
IUUC-Mac-064636	Musa acuminata	59.63	0.00e+00	1085.00
IUUC-Mpu-065961	Mustela putorius furo	88.70	0.00e+00	1676.00
IUUC-Mlu-067059	Myotis lucifugus	93.14	0.00e+00	1620.00
IUUC-Nfi-068277	Neosartorya fischeri	54.70	0.00e+00	924.00
IUUC-Ncr-068659	Neurospora crassa	52.93	0.00e+00	907.00
IUUC-Nle-069034	Nomascus leucogenys	88.59	0.00e+00	1680.00
IUUC-Opr-070334	Ochotona princeps	94.83	0.00e+00	1475.00
IUUC-Oan-073416	Ornithorhynchus anatinus	93.77	0.00e+00	1601.00
IUUC-Ocu-074522	Oryctolagus cuniculus	88.70	0.00e+00	1674.00
IUUC-Oba-075760	Oryza barthii	60.86	0.00e+00	1070.00
IUUC-Obr-076201	Oryza brachyantha	61.84	0.00e+00	1102.00
IUUC-Ogl-077450	Oryza glaberrima	62.10	0.00e+00	1098.00
IUUC-Ogu-078994	Oryza glumaepatula	60.86	0.00e+00	1069.00
IUUC-Oin-079856	Oryza indica	60.63	0.00e+00	1075.00
IUUC-Olo-080731	Oryza longistaminata	58.96	0.00e+00	1057.00
IUUC-Ome-081554	Oryza meridionalis	57.42	0.00e+00	997.00
IUUC-Oni-082324	Oryza nivara	60.86	0.00e+00	1070.00
IUUC-Opu-083400	Oryza punctata	57.42	0.00e+00	1063.00
IUUC-Oru-084829	Oryza rufipogon	60.86	0.00e+00	1070.00
IUUC-Osa-086026	Oryza sativa	62.10	0.00e+00	1102.00
IUUC-Ola-087245	Oryzias latipes	94.52	0.00e+00	1778.00
IUUC-Olu-087655	Ostreococcus lucimarinus	59.73	0.00e+00	1051.00
IUUC-Oga-088163	Otolemur garnettii	85.38	0.00e+00	1604.00
IUUC-Oar-089842	Ovis aries	93.73	0.00e+00	1674.00
IUUC-Ptr-090501	Pan troglodytes	88.48	0.00e+00	1675.00
IUUC-Pan-092011	Papio anubis	88.70	0.00e+00	1682.00
IUUC-Psi-093308	Pelodiscus sinensis	94.00	0.00e+00	1686.00
IUUC-Pma-094695	Petromyzon marinus	80.42	0.00e+00	1431.00
IUUC-Pno-094785	Phaeosphaeria nodorum	62.07	3.00e-111	396.00
IUUC-Ppa-095911	Physcomitrella patens	61.37	0.00e+00	1121.00
IUUC-Pfo-096587	Poecilia formosa	92.80	0.00e+00	1786.00
IUUC-Pab-097926	Pongo abelii	86.19	0.00e+00	1584.00
IUUC-Pop-099634	Populus trichocarpa	61.91	0.00e+00	1104.00
IUUC-Pca-100965	Procavia capensis	92.06	0.00e+00	1628.00
IUUC-Ppe-101470	Prunus persica	62.15	0.00e+00	1114.00
IUUC-Pva-102451	Pteropus vampyrus	88.57	0.00e+00	1230.00
IUUC-Pgr-103453	Puccinia graminis	53.32	0.00e+00	917.00
IUUC-Ptt-103868	Puccinia triticina	53.42	0.00e+00	913.00
IUUC-Pte-104274	Pyrenophora teres	55.27	0.00e+00	947.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	54.73	0.00e+00	899.00
IUUC-Rno-105979	Rattus norvegicus	81.55	0.00e+00	1229.00
IUUC-Sce-106269	Saccharomyces cerevisiae	47.04	0.00e+00	781.00
IUUC-Sha-106905	Sarcophilus harrisii	94.33	0.00e+00	1689.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	47.72	0.00e+00	829.00
IUUC-Spo-108299	Schizosaccharomyces pombe	46.27	0.00e+00	820.00
IUUC-Smo-108828	Selaginella moellendorffii	62.10	0.00e+00	1079.00
IUUC-Sit-110692	Setaria italica	61.08	0.00e+00	1098.00
IUUC-Sly-111525	Solanum lycopersicum	61.31	0.00e+00	1114.00
IUUC-Stu-112906	Solanum tuberosum	59.85	0.00e+00	989.00
IUUC-Sar-113472	Sorex araneus	87.54	0.00e+00	1123.00
IUUC-Sbi-114052	Sorghum bicolor	63.04	0.00e+00	1113.00
IUUC-Sre-115040	Sporisorium reilianum	52.25	0.00e+00	913.00
IUUC-Ssc-115593	Sus scrofa	88.81	0.00e+00	1680.00
IUUC-Tgu-117239	Taeniopygia guttata	94.21	0.00e+00	1686.00
IUUC-Tru-118025	Takifugu rubripes	96.86	0.00e+00	1744.00
IUUC-Tsy-118824	Tarsius syrichta	86.78	0.00e+00	1132.00
IUUC-Tni-120142	Tetraodon nigroviridis	97.08	0.00e+00	1741.00
IUUC-Tca-121613	Theobroma cacao	62.03	0.00e+00	1112.00
IUUC-Tre-122072	Trichoderma reesei	54.38	0.00e+00	919.00
IUUC-Tvi-122546	Trichoderma virens	54.09	0.00e+00	905.00
IUUC-Tae-125292	Triticum aestivum	61.90	0.00e+00	1095.00
IUUC-Tur-126283	Triticum urartu	54.26	0.00e+00	935.00
IUUC-Tme-127041	Tuber melanosporum	56.13	0.00e+00	976.00
IUUC-Tbe-127770	Tupaia belangeri	89.16	0.00e+00	1236.00
IUUC-Ttr-129294	Tursiops truncatus	88.59	0.00e+00	1679.00
IUUC-Uma-129351	Ustilago maydis	51.04	0.00e+00	904.00
IUUC-Vda-129716	Verticillium dahliae	55.11	0.00e+00	942.00
IUUC-Vpa-130037	Vicugna pacos	78.31	0.00e+00	831.00
IUUC-Vvi-131689	Vitis vinifera	61.50	0.00e+00	1105.00
IUUC-Xtr-132633	Xenopus tropicalis	89.33	0.00e+00	1663.00
IUUC-Xma-133347	Xiphophorus maculatus	94.65	0.00e+00	1796.00
IUUC-Yli-134455	Yarrowia lipolytica	50.25	0.00e+00	835.00
IUUC-Zma-135706	Zea mays	60.73	0.00e+00	1112.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence