iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tme-127041

Ensembl Protein ID

CAZ79731

UniProt Accession

D5G5D8; D5G5D8_TUBMM

Genbank Protein ID

CAZ79731.1

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

FN429998

Gene Name

GSTUM_00004287001

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSTUM_00004287001	CAZ79731	CAZ79731

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.70e-27	91.9	227	257
UBD/Beta-Prp	4.10e-65	218.5	12	297

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHt+ v+  +f ++ + +vsGs Dgt+k+W 
   Q: 227  GHTSNVSFACFhPElPVIVSGSEDGTVKIWH 257
           8*******9***999***************6 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdkl 109
           ++++++ ++f+p +++++++ ++g + +w+ +t++l+++++  + +v+a +f+ +++++v gs+D +++v++++t++ + ++++h d+++s+ ++p++ ++
   Q: 12   RSDRVKGIDFHPIEPWVLSTLYSGHVNIWSHETQTLVKTFEVTDVPVRAGRFIARKNWFVVGSDDFHLRVFNYNTSEKIAAFEAHPDYIRSIVVHPTQPFV 112
           678999*********************************************************************************************** PP
   S: 110  vsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvkl 206
           +++s+d ti++wd+e+g++  +t++gh + v++++++p++ n ++s++lDrtv++W+l   g+   tl+   t+ v+++++ +    +++++ s+d+t+k+
   Q: 113  LTASDDMTIKLWDWEKGWKCVQTFEGHAHYVMSLAINPKDtNTFASACLDRTVKIWSLgGGGNANFTLEAHETKGVNHVDYYPAAdkPYILTTSDDRTIKI 213
           *****************98888************************************77789999999999********8776666************** PP
   S: 207  wdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvni 291
           wd+ t++ + tl+ght+nv+   f+p+   +vsgs+Dg+++iW   +  l +tl++  ++ ++v+  + g+n ++ g ++++v +
   Q: 214  WDYTTKSLIATLEGHTSNVSFACFHPELPVIVSGSEDGTVKIWHANTYRLEQTLNYGLERAWCVSS-QKGKNAIAMGFDEGCVVV 297
           *****************************************************************9.555555555544555544 PP

Organism

Tuber melanosporum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MRLDVKRQLF ARSDRVKGID FHPIEPWVLS TLYSGHVNIW SHETQTLVKT FEVTDVPVRA 60
GRFIARKNWF VVGSDDFHLR VFNYNTSEKI AAFEAHPDYI RSIVVHPTQP FVLTASDDMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGAAAAGTC CTCCCCAACA ACCCAGCATC AGGAATTACG GAACAGCTAT AGAACAGCAT 60
GCGGCTAGAC GTGAAGGTAA AGCTCCTCCT TGTTATTTTA TCAAGTCCCA GCAAAACAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0005829--C:cytosol
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0032511--P:late endosome to vacuole transport via multivesicular body sorting pathway
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

tml:GSTUM_00004287001

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	46.22	0.00e+00	769.00
IUUC-Aml-002154	Ailuropoda melanoleuca	56.54	0.00e+00	982.00
IUUC-Atr-003090	Amborella trichopoda	54.99	0.00e+00	888.00
IUUC-Apl-003976	Anas platyrhynchos	57.04	0.00e+00	987.00
IUUC-Aca-004301	Anolis carolinensis	56.91	0.00e+00	989.00
IUUC-Aly-006508	Arabidopsis lyrata	53.13	0.00e+00	899.00
IUUC-Ath-007635	Arabidopsis thaliana	53.06	0.00e+00	899.00
IUUC-Ago-007914	Ashbya gossypii	51.07	0.00e+00	851.00
IUUC-Acl-008237	Aspergillus clavatus	76.40	0.00e+00	1331.00
IUUC-Afl-008535	Aspergillus flavus	74.94	0.00e+00	1280.00
IUUC-Afu-008845	Aspergillus fumigatus	76.43	0.00e+00	1299.00
IUUC-Ani-009135	Aspergillus nidulans	74.94	0.00e+00	1283.00
IUUC-Ang-009654	Aspergillus niger	80.18	0.00e+00	1145.00
IUUC-Aor-009939	Aspergillus oryzae	75.71	0.00e+00	1353.00
IUUC-Ate-010355	Aspergillus terreus	75.95	0.00e+00	1285.00
IUUC-Ame-010922	Astyanax mexicanus	51.28	0.00e+00	850.00
IUUC-Bgr-012249	Blumeria graminis	75.03	0.00e+00	1285.00
IUUC-Bta-013579	Bos taurus	57.04	0.00e+00	888.00
IUUC-Bci-013866	Botrytis cinerea	77.37	0.00e+00	1294.00
IUUC-Bdi-015046	Brachypodium distachyon	53.13	0.00e+00	907.00
IUUC-Bol-016271	Brassica oleracea	53.01	0.00e+00	911.00
IUUC-Bra-017758	Brassica rapa	53.07	0.00e+00	911.00
IUUC-Cel-018387	Caenorhabditis elegans	52.69	0.00e+00	913.00
IUUC-Cja-019145	Callithrix jacchus	56.54	0.00e+00	983.00
IUUC-Cfa-020564	Canis familiaris	56.54	0.00e+00	982.00
IUUC-Cpo-022201	Cavia porcellus	56.41	0.00e+00	981.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	54.00	0.00e+00	864.00
IUUC-Csa-023383	Chlorocebus sabaeus	60.35	0.00e+00	751.00
IUUC-Cho-024454	Choloepus hoffmanni	53.59	0.00e+00	839.00
IUUC-Cin-025681	Ciona intestinalis	55.97	0.00e+00	918.00
IUUC-Csv-026012	Ciona savignyi	56.51	0.00e+00	907.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	70.64	0.00e+00	1160.00
IUUC-Cne-026986	Cryptococcus neoformans	59.45	0.00e+00	996.00
IUUC-Cme-027219	Cyanidioschyzon merolae	44.90	0.00e+00	770.00
IUUC-Dre-027846	Danio rerio	56.41	0.00e+00	985.00
IUUC-Dor-030462	Dipodomys ordii	54.94	0.00e+00	784.00
IUUC-Dse-031268	Dothistroma septosporum	73.34	0.00e+00	1276.00
IUUC-Dme-031791	Drosophila melanogaster	52.70	0.00e+00	907.00
IUUC-Ete-033166	Echinops telfairi	53.48	3.00e-180	623.00
IUUC-Eca-034180	Equus caballus	54.60	0.00e+00	936.00
IUUC-Eeu-035086	Erinaceus europaeus	44.29	8.00e-104	369.00
IUUC-Fca-036265	Felis catus	56.54	0.00e+00	981.00
IUUC-Fal-037202	Ficedula albicollis	56.44	0.00e+00	942.00
IUUC-Fox-037711	Fusarium oxysporum	75.55	0.00e+00	1214.00
IUUC-Fso-038268	Fusarium solani	75.43	0.00e+00	1208.00
IUUC-Gmo-039046	Gadus morhua	56.13	0.00e+00	984.00
IUUC-Ggr-039863	Gaeumannomyces graminis	75.68	0.00e+00	1244.00
IUUC-Gga-041112	Gallus gallus	56.66	0.00e+00	984.00
IUUC-Gac-041733	Gasterosteus aculeatus	56.25	0.00e+00	954.00
IUUC-Gma-042910	Glycine max	53.55	0.00e+00	919.00
IUUC-Ggo-044984	Gorilla gorilla	56.54	0.00e+00	982.00
IUUC-Hsa-046698	Homo sapiens	56.54	0.00e+00	982.00
IUUC-Hvu-047669	Hordeum vulgare	60.56	1.00e-137	480.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	56.54	0.00e+00	980.00
IUUC-Kpa-049265	Komagataella pastoris	57.79	0.00e+00	988.00
IUUC-Lch-050473	Latimeria chalumnae	55.92	0.00e+00	976.00
IUUC-Lpe-051579	Leersia perrieri	52.88	0.00e+00	896.00
IUUC-Loc-052675	Lepisosteus oculatus	56.29	0.00e+00	983.00
IUUC-Lma-053218	Leptosphaeria maculans	71.27	0.00e+00	1202.00
IUUC-Laf-053757	Loxodonta africana	56.52	0.00e+00	976.00
IUUC-Mcc-054859	Macaca mulatta	56.54	0.00e+00	982.00
IUUC-Meu-056174	Macropus eugenii	48.35	3.00e-94	338.00
IUUC-Mor-057264	Magnaporthe oryzae	74.64	0.00e+00	1219.00
IUUC-Mpo-057538	Magnaporthe poae	75.18	0.00e+00	1263.00
IUUC-Mtr-058310	Medicago truncatula	52.82	0.00e+00	915.00
IUUC-Mla-058937	Melampsora laricipopulina	58.10	0.00e+00	976.00
IUUC-Mga-059875	Meleagris gallopavo	55.49	0.00e+00	981.00
IUUC-Mvi-060240	Microbotryum violaceum	56.69	0.00e+00	999.00
IUUC-Mmr-061261	Microcebus murinus	56.54	0.00e+00	982.00
IUUC-Mdo-062076	Monodelphis domestica	56.79	0.00e+00	988.00
IUUC-Mmu-063324	Mus musculus	56.66	0.00e+00	984.00
IUUC-Mac-064636	Musa acuminata	52.55	0.00e+00	902.00
IUUC-Mpu-065961	Mustela putorius furo	56.54	0.00e+00	981.00
IUUC-Mlu-067059	Myotis lucifugus	55.79	0.00e+00	949.00
IUUC-Nfi-068277	Neosartorya fischeri	76.23	0.00e+00	1289.00
IUUC-Ncr-068659	Neurospora crassa	73.06	0.00e+00	1266.00
IUUC-Nle-069034	Nomascus leucogenys	56.54	0.00e+00	982.00
IUUC-Opr-070334	Ochotona princeps	57.65	0.00e+00	914.00
IUUC-Ont-071563	Oreochromis niloticus	56.13	0.00e+00	983.00
IUUC-Oan-073416	Ornithorhynchus anatinus	56.19	0.00e+00	938.00
IUUC-Ocu-074522	Oryctolagus cuniculus	56.29	0.00e+00	976.00
IUUC-Oba-075760	Oryza barthii	52.70	0.00e+00	890.00
IUUC-Obr-076163	Oryza brachyantha	52.64	0.00e+00	893.00
IUUC-Ogl-077450	Oryza glaberrima	53.19	0.00e+00	911.00
IUUC-Ogu-078994	Oryza glumaepatula	52.70	0.00e+00	889.00
IUUC-Oin-079856	Oryza indica	52.29	0.00e+00	880.00
IUUC-Olo-080731	Oryza longistaminata	53.37	0.00e+00	876.00
IUUC-Ome-081762	Oryza meridionalis	49.51	0.00e+00	814.00
IUUC-Oni-082324	Oryza nivara	52.70	0.00e+00	890.00
IUUC-Opu-083400	Oryza punctata	50.12	0.00e+00	861.00
IUUC-Oru-084829	Oryza rufipogon	52.70	0.00e+00	890.00
IUUC-Osa-086026	Oryza sativa	53.44	0.00e+00	915.00
IUUC-Ola-087245	Oryzias latipes	55.64	0.00e+00	978.00
IUUC-Olu-087655	Ostreococcus lucimarinus	53.51	0.00e+00	904.00
IUUC-Oga-088163	Otolemur garnettii	54.66	0.00e+00	936.00
IUUC-Oar-089842	Ovis aries	56.54	0.00e+00	981.00
IUUC-Ptr-090501	Pan troglodytes	56.54	0.00e+00	981.00
IUUC-Pan-092011	Papio anubis	56.54	0.00e+00	983.00
IUUC-Psi-093308	Pelodiscus sinensis	56.91	0.00e+00	987.00
IUUC-Pma-094695	Petromyzon marinus	55.60	0.00e+00	905.00
IUUC-Pno-094785	Phaeosphaeria nodorum	77.93	1.00e-137	481.00
IUUC-Ppa-095412	Physcomitrella patens	53.96	0.00e+00	927.00
IUUC-Pfo-096587	Poecilia formosa	55.76	0.00e+00	982.00
IUUC-Pab-097926	Pongo abelii	55.25	0.00e+00	908.00
IUUC-Pop-099634	Populus trichocarpa	53.36	0.00e+00	918.00
IUUC-Pca-100965	Procavia capensis	55.79	0.00e+00	950.00
IUUC-Ppe-101470	Prunus persica	53.37	0.00e+00	913.00
IUUC-Pva-102451	Pteropus vampyrus	54.19	0.00e+00	771.00
IUUC-Pgr-103453	Puccinia graminis	58.19	0.00e+00	993.00
IUUC-Ptt-103868	Puccinia triticina	58.68	0.00e+00	996.00
IUUC-Pte-104274	Pyrenophora teres	73.02	0.00e+00	1243.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	69.59	0.00e+00	1186.00
IUUC-Rno-105979	Rattus norvegicus	49.16	0.00e+00	730.00
IUUC-Sce-106269	Saccharomyces cerevisiae	53.12	0.00e+00	882.00
IUUC-Sha-106905	Sarcophilus harrisii	56.79	0.00e+00	987.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	54.99	0.00e+00	920.00
IUUC-Spo-108299	Schizosaccharomyces pombe	54.28	0.00e+00	935.00
IUUC-Smo-108695	Selaginella moellendorffii	52.93	0.00e+00	910.00
IUUC-Sit-110239	Setaria italica	53.44	0.00e+00	913.00
IUUC-Sly-111775	Solanum lycopersicum	53.66	0.00e+00	909.00
IUUC-Stu-112906	Solanum tuberosum	52.63	0.00e+00	820.00
IUUC-Sar-113472	Sorex araneus	53.29	0.00e+00	698.00
IUUC-Sbi-114052	Sorghum bicolor	53.62	0.00e+00	920.00
IUUC-Sre-115040	Sporisorium reilianum	58.22	0.00e+00	989.00
IUUC-Ssc-115593	Sus scrofa	56.41	0.00e+00	980.00
IUUC-Tgu-117239	Taeniopygia guttata	56.91	0.00e+00	988.00
IUUC-Tru-118025	Takifugu rubripes	56.59	0.00e+00	979.00
IUUC-Tsy-118824	Tarsius syrichta	53.72	0.00e+00	715.00
IUUC-Tni-120142	Tetraodon nigroviridis	56.54	0.00e+00	976.00
IUUC-Tca-121613	Theobroma cacao	53.68	0.00e+00	919.00
IUUC-Tre-122072	Trichoderma reesei	74.73	0.00e+00	1260.00
IUUC-Tvi-122546	Trichoderma virens	74.57	0.00e+00	1262.00
IUUC-Tae-125395	Triticum aestivum	53.32	0.00e+00	912.00
IUUC-Tur-126283	Triticum urartu	46.46	0.00e+00	768.00
IUUC-Tbe-127770	Tupaia belangeri	55.99	0.00e+00	807.00
IUUC-Ttr-129294	Tursiops truncatus	56.41	0.00e+00	979.00
IUUC-Uma-129351	Ustilago maydis	57.00	0.00e+00	993.00
IUUC-Vda-129716	Verticillium dahliae	76.23	0.00e+00	1313.00
IUUC-Vpa-130037	Vicugna pacos	45.35	3.00e-111	394.00
IUUC-Vvi-131689	Vitis vinifera	53.80	0.00e+00	915.00
IUUC-Xtr-132633	Xenopus tropicalis	55.92	0.00e+00	973.00
IUUC-Xma-133347	Xiphophorus maculatus	55.88	0.00e+00	983.00
IUUC-Yli-134455	Yarrowia lipolytica	57.78	0.00e+00	964.00
IUUC-Zma-135867	Zea mays	53.50	0.00e+00	920.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence