iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091625

UUCD1 version

UUC-PaT-00068

Ensembl Protein ID

ENSPTRP00000001898.5

UniProt Accession

G2HGD5; G2HGD5_PANTR

Genbank Protein ID

BAK62793.1; JAA03427.1; JAA13564.1; JAA26963.1; JAA35765.1

Protein Name

Methylosome protein 50; WD repeat domain 77

Genbank Nucleotide ID

AACZ03007062; GABC01007911; GABF01008581; GABD01006137; GABE01008974

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000001098.5	ENSPTRT00000002065.5	ENSPTRP00000001898.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.50e-17	61.5	124	160

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H d v+ ++  s+ t  vsGs D  ikvWDl ++v+l
   Q: 124  HDDIVSTVSVlSSgTQAVSGSKDICIKVWDLAQQVVL 160
           89999999977555*****************999987 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MRKETPPPLV PPAAREWNLP PNAPACMERQ LEAARYRSDG ALLLGASSLS GRCWAGSLWL 60
FKDPCAAPNE GFCSAGVQTE AGVADLTWVG ERGILVASDS GAVELWELDE NETLIVSKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTCCAGTTT GAGTCTAGGT TGGAGTTGGA ACCGTGGAGA TGCGGAAGGA AACCCCACCC 60
CCCCTAGTGC CCCCGGCGGC CCGGGAGTGG AATCTTCCCC CAAATGCGCC CGCCTGCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

KEGG

ptr:744535

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	91.55	5.00e-179	619.00
IUUC-Apl-003921	Anas platyrhynchos	63.16	2.00e-66	244.00
IUUC-Aca-004870	Anolis carolinensis	69.89	1.00e-118	419.00
IUUC-Ame-011872	Astyanax mexicanus	47.78	1.00e-38	152.00
IUUC-Bta-013325	Bos taurus	92.11	0.00e+00	627.00
IUUC-Cja-019059	Callithrix jacchus	97.08	0.00e+00	649.00
IUUC-Cfa-021036	Canis familiaris	91.41	2.00e-157	548.00
IUUC-Cpo-022369	Cavia porcellus	90.06	2.00e-177	614.00
IUUC-Csa-023585	Chlorocebus sabaeus	98.25	0.00e+00	658.00
IUUC-Cho-024470	Choloepus hoffmanni	82.99	8.00e-115	405.00
IUUC-Dno-029867	Dasypus novemcinctus	88.89	1.00e-177	615.00
IUUC-Dor-030834	Dipodomys ordii	64.14	6.00e-114	403.00
IUUC-Ete-032245	Echinops telfairi	82.82	7.00e-140	489.00
IUUC-Eca-033360	Equus caballus	91.52	3.00e-173	600.00
IUUC-Eeu-035353	Erinaceus europaeus	89.77	8.00e-177	612.00
IUUC-Fca-036277	Felis catus	92.69	0.00e+00	628.00
IUUC-Fal-037383	Ficedula albicollis	66.67	9.00e-102	362.00
IUUC-Gmo-038575	Gadus morhua	54.95	7.00e-101	360.00
IUUC-Gga-040658	Gallus gallus	69.63	7.00e-129	453.00
IUUC-Gac-041463	Gasterosteus aculeatus	52.35	2.00e-85	309.00
IUUC-Ggo-045120	Gorilla gorilla	99.12	0.00e+00	664.00
IUUC-Hsa-046247	Homo sapiens	99.42	0.00e+00	666.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	94.15	8.00e-180	622.00
IUUC-Lch-049741	Latimeria chalumnae	65.19	4.00e-112	397.00
IUUC-Loc-052695	Lepisosteus oculatus	59.58	7.00e-107	380.00
IUUC-Laf-054535	Loxodonta africana	88.51	4.00e-175	607.00
IUUC-Mcc-054699	Macaca mulatta	98.25	0.00e+00	658.00
IUUC-Meu-056053	Macropus eugenii	76.09	1.00e-138	486.00
IUUC-Mga-059672	Meleagris gallopavo	64.95	2.00e-71	261.00
IUUC-Mmr-060963	Microcebus murinus	93.27	0.00e+00	636.00
IUUC-Mdo-062694	Monodelphis domestica	74.05	3.00e-133	468.00
IUUC-Mmu-064031	Mus musculus	89.18	5.00e-176	610.00
IUUC-Mpu-066408	Mustela putorius furo	92.11	0.00e+00	627.00
IUUC-Mlu-068184	Myotis lucifugus	89.50	9.00e-175	605.00
IUUC-Nle-069251	Nomascus leucogenys	97.95	0.00e+00	658.00
IUUC-Opr-071156	Ochotona princeps	84.50	3.00e-164	570.00
IUUC-Ont-072683	Oreochromis niloticus	57.63	4.00e-98	350.00
IUUC-Oan-073042	Ornithorhynchus anatinus	75.17	8.00e-126	442.00
IUUC-Ocu-074843	Oryctolagus cuniculus	93.00	4.00e-176	610.00
IUUC-Ola-086929	Oryzias latipes	53.85	8.00e-90	323.00
IUUC-Oga-088237	Otolemur garnettii	92.11	1.00e-180	625.00
IUUC-Oar-089312	Ovis aries	91.77	3.00e-165	573.00
IUUC-Pan-091902	Papio anubis	93.31	4.00e-179	620.00
IUUC-Psi-094035	Pelodiscus sinensis	71.19	1.00e-125	441.00
IUUC-Pma-094565	Petromyzon marinus	64.04	2.00e-57	214.00
IUUC-Pfo-097070	Poecilia formosa	54.81	4.00e-93	334.00
IUUC-Pab-098007	Pongo abelii	99.42	0.00e+00	666.00
IUUC-Pca-100513	Procavia capensis	73.68	2.00e-103	368.00
IUUC-Pva-102821	Pteropus vampyrus	86.55	3.00e-165	573.00
IUUC-Rno-105836	Rattus norvegicus	88.22	1.00e-176	612.00
IUUC-Sha-106847	Sarcophilus harrisii	69.80	2.00e-88	318.00
IUUC-Sar-113451	Sorex araneus	84.84	1.00e-167	582.00
IUUC-Ssc-115978	Sus scrofa	90.94	2.00e-173	601.00
IUUC-Tgu-116745	Taeniopygia guttata	68.86	2.00e-94	338.00
IUUC-Tru-117945	Takifugu rubripes	53.11	5.00e-82	297.00
IUUC-Tsy-119059	Tarsius syrichta	88.70	8.00e-91	325.00
IUUC-Tni-120414	Tetraodon nigroviridis	54.91	3.00e-95	341.00
IUUC-Tbe-127559	Tupaia belangeri	94.74	0.00e+00	642.00
IUUC-Ttr-128505	Tursiops truncatus	89.77	2.00e-174	604.00
IUUC-Vpa-130350	Vicugna pacos	93.41	4.00e-100	356.00
IUUC-Xtr-132939	Xenopus tropicalis	62.15	1.00e-113	402.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence