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Tag Content
UUCD2 ID IUUC-Ssc-116133
UUCD1 version UUC-SuS-00152
Ensembl Protein ID ENSSSCP00000010203.2
UniProt Accession F1RN43; F1RN43_PIG
Genbank Protein ID ENSSSCP00000010203
Protein Name Uncharacterized protein
Genbank Nucleotide ID FP236214
Gene Name CUL4A
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSSCG00000009556.2 ENSSSCT00000010475.2 ENSSSCP00000010203.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 3.60e-216 719.9 67 662
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 1    klreavkkilrqesvkkeyeelytavynlclskvgaklYkklkevleefi.kqvkkkveesedeq.lLktynreWekfreqlkvlrkif 87
           kl+eavk+i++++s+++++eely+av+nlc++kv+  lY++l+e++e+++ +q+ +   +s d+  +Lk++n++W+++++q+ ++r+if
   Q: 67   KLHEAVKAIQSSTSIRYNLEELYQAVENLCSHKVAPTLYQQLREACESHVqAQILQVCTDSLDSVfFLKKINTCWQDHCRQMIMVRSIF 155
           5899**********************************************99************************************* PP
   S: 88   ayldrtyvkkskkvsevrkLaldlwrkeived..ikkrllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakfle 174
           ++ldrtyv +++ + ++++++l+l+r ++++d  +++++++ +l li++eR+geavdr+ll+g+  +l++L     ++yk+sFE kfle
   Q: 156  LFLDRTYVLQNSLLPSIWDMGLELFRSHVISDrmVQTKTIDGILLLIARERSGEAVDRSLLRGLLGMLSDL-----QVYKDSFELKFLE 239
           **********9999*****************************************************9998.....9************ PP
   S: 175  atqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesll.aelvallrdkktedlsrmykLl 262
           +t+ +y+ae ++++qe+ev eYl++v +rl+ee +r+ +yl++st+++L+++vek+l+ +hl+++l ++l++ll++++  dl++my+L+
   Q: 240  ETNCLYAAEGQRLMQEREVPEYLNHVSKRLEEEGDRVITYLDHSTQKPLIACVEKQLLGEHLTAILqKGLDHLLDENRVPDLTQMYQLF 328
           ****************************************************************9989********************* PP
   S: 263  srvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlkaaksp.E 350
           srv+ g + ll++++++ik+ g+++++++ek+kd   +V++ll++k++++++++ +F+ ++kF++ ++++fe+f+nk+     +++p E
   Q: 329  SRVRGGQQALLQHWSEYIKTFGTTIVINPEKDKD---MVQDLLDFKDRVDHVIDVCFQRNEKFINLMKESFEAFINKR-----PNKPaE 409
           **********************************...*****************************************.....66666* PP
   S: 351  llAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfq 439
           l+A+++D++Lr+++k++t+eele++ldkv+++f++i++kdvFe++Ykk+LakRLl+gksas +aE+s+++kLk+ecga+ftskLe+Mf+
   Q: 410  LIAKHVDSKLRAGNKEATDEELERILDKVMIIFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFK 498
           ***************************************************************************************** PP
   S: 440  dlkvSedlnrqFkeekenteesesvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkk 528
           d+++S+d++ +Fk+ ++n+++  s++l+v++L++g+Wpt++ +  v+L++e+ k++e f++fYl khsgRkLqWq+ lg+a lkae+k+
   Q: 499  DMELSKDIMVHFKQYMQNQSDPGSIDLTVNILTMGYWPTYTPMD-VHLTPEMVKLQEVFKTFYLGKHSGRKLQWQTALGHAVLKAEFKE 586
           ****************************************9988.******************************************** PP
   S: 529  gkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvsskkqvlkkepeskeieeedlfsvNqef 604
           gk+e+qVs fQ++vLL+fn+ + + +ee+k+at+++++eLrrtlqsL+++k++vl k+p++ke+e++d+f +N +f
   Q: 587  GKKEFQVSLFQTLVLLMFNEGDGFGFEEIKAATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFFFNGDF 662
           *************************************************************************998 PP
   
Organism Sus scrofa
Protein Sequence
(Fasta)
MADETPRKGS FSALVGHTNG LTKPASLAAA AVTSKPGGSG GSKKLVIKNF RDRPKLPDNY 60
TQDTWHKLHE AVKAIQSSTS IRYNLEELYQ AVENLCSHKV APTLYQQLRE ACESHVQAQI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ssc-116133|E3,Cullin|Sus scrofa
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGGTCCGTCC CGGCCCCGCG CCCCCCGCCC TCCGCGCACC TTGGTTCCGG AGGCAGCCTG 60
TGCGCGGGAA CGCGAGCCCC GGGCCGGCAT GGCGGCGCGC CCGGGCTGAG GCGGGCTGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ssc-116133|E3,Cullin|Sus scrofa
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8
SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8
Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0030097--P:hemopoiesis
GO:0001701--P:in utero embryonic development
GO:0030853--P:negative regulation of granulocyte differentiation
GO:0008284--P:positive regulation of cell proliferation
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:2000001--P:regulation of DNA damage checkpoint
GO:2000819--P:regulation of nucleotide-excision repair
GO:0051246--P:regulation of protein metabolic process
GO:0035019--P:somatic stem cell population maintenance
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000285 Aegilops tauschii 56.20 0.00e+00 821.00
IUUC-Aml-001592 Ailuropoda melanoleuca 93.36 0.00e+00 1380.00
IUUC-Atr-002727 Amborella trichopoda 57.39 0.00e+00 806.00
IUUC-Apl-003269 Anas platyrhynchos 90.70 0.00e+00 1317.00
IUUC-Aca-004430 Anolis carolinensis 82.09 0.00e+00 1248.00
IUUC-Aly-006547 Arabidopsis lyrata 56.97 0.00e+00 809.00
IUUC-Ath-006748 Arabidopsis thaliana 56.56 0.00e+00 802.00
IUUC-Acl-008359 Aspergillus clavatus 35.76 9.00e-124 437.00
IUUC-Afl-008567 Aspergillus flavus 38.65 1.00e-139 490.00
IUUC-Afu-008833 Aspergillus fumigatus 37.55 1.00e-133 470.00
IUUC-Ani-009373 Aspergillus nidulans 39.11 2.00e-141 496.00
IUUC-Ang-009622 Aspergillus niger 38.50 8.00e-137 481.00
IUUC-Aor-010241 Aspergillus oryzae 38.90 2.00e-133 469.00
IUUC-Ate-010251 Aspergillus terreus 38.92 9.00e-141 493.00
IUUC-Ame-011580 Astyanax mexicanus 82.14 0.00e+00 1258.00
IUUC-Bgr-012219 Blumeria graminis 36.52 4.00e-116 412.00
IUUC-Bta-012355 Bos taurus 94.03 0.00e+00 1385.00
IUUC-Bci-013744 Botrytis cinerea 38.94 2.00e-126 446.00
IUUC-Bdi-014223 Brachypodium distachyon 53.93 0.00e+00 821.00
IUUC-Bol-015666 Brassica oleracea 57.03 0.00e+00 844.00
IUUC-Bra-017794 Brassica rapa 57.10 0.00e+00 832.00
IUUC-Cja-019861 Callithrix jacchus 93.16 0.00e+00 1369.00
IUUC-Cfa-021009 Canis familiaris 94.35 0.00e+00 1425.00
IUUC-Cpo-021867 Cavia porcellus 91.98 0.00e+00 1414.00
IUUC-Cre-022739 Chlamydomonas reinhardtii 47.37 1.00e-175 609.00
IUUC-Csa-024139 Chlorocebus sabaeus 92.64 0.00e+00 1397.00
IUUC-Cho-024899 Choloepus hoffmanni 96.43 0.00e+00 1014.00
IUUC-Cin-025727 Ciona intestinalis 61.24 0.00e+00 758.00
IUUC-Csv-026117 Ciona savignyi 52.96 0.00e+00 859.00
IUUC-Cgl-026761 Colletotrichum gloeosporioides 38.56 1.00e-124 440.00
IUUC-Cne-027048 Cryptococcus neoformans 33.54 5.00e-95 342.00
IUUC-Cme-027355 Cyanidioschyzon merolae 34.08 1.00e-116 413.00
IUUC-Dre-027916 Danio rerio 81.82 0.00e+00 1230.00
IUUC-Dno-028879 Dasypus novemcinctus 87.27 0.00e+00 1348.00
IUUC-Dor-030698 Dipodomys ordii 91.33 0.00e+00 1378.00
IUUC-Dse-031159 Dothistroma septosporum 37.34 2.00e-126 446.00
IUUC-Dme-031652 Drosophila melanogaster 63.66 0.00e+00 943.00
IUUC-Ete-033101 Echinops telfairi 87.92 0.00e+00 1258.00
IUUC-Eca-033696 Equus caballus 93.36 0.00e+00 1370.00
IUUC-Eeu-034767 Erinaceus europaeus 76.87 0.00e+00 1154.00
IUUC-Fca-036333 Felis catus 94.23 0.00e+00 1376.00
IUUC-Fal-036995 Ficedula albicollis 90.68 0.00e+00 1335.00
IUUC-Fox-037854 Fusarium oxysporum 38.75 1.00e-125 443.00
IUUC-Fso-038138 Fusarium solani 38.11 2.00e-126 446.00
IUUC-Gmo-038754 Gadus morhua 80.21 0.00e+00 1237.00
IUUC-Ggr-040003 Gaeumannomyces graminis 35.71 1.00e-103 370.00
IUUC-Gga-040358 Gallus gallus 88.30 0.00e+00 1375.00
IUUC-Gac-041555 Gasterosteus aculeatus 83.13 0.00e+00 1256.00
IUUC-Gma-043960 Glycine max 58.67 0.00e+00 842.00
IUUC-Ggo-045468 Gorilla gorilla 81.62 0.00e+00 1205.00
IUUC-Hsa-045679 Homo sapiens 92.64 0.00e+00 1399.00
IUUC-Itr-048182 Ictidomys tridecemlineatus 92.73 0.00e+00 1275.00
IUUC-Kpa-049372 Komagataella pastoris 30.97 9.00e-95 340.00
IUUC-Lch-050417 Latimeria chalumnae 86.20 0.00e+00 1338.00
IUUC-Lpe-051446 Leersia perrieri 55.98 0.00e+00 824.00
IUUC-Loc-051804 Lepisosteus oculatus 83.29 0.00e+00 1278.00
IUUC-Lma-053080 Leptosphaeria maculans 35.98 4.00e-131 461.00
IUUC-Laf-054100 Loxodonta africana 92.92 0.00e+00 1363.00
IUUC-Mcc-055168 Macaca mulatta 93.92 0.00e+00 1256.00
IUUC-Meu-056492 Macropus eugenii 73.09 3.00e-171 595.00
IUUC-Mor-057102 Magnaporthe oryzae 34.61 7.00e-117 414.00
IUUC-Mpo-057342 Magnaporthe poae 35.74 4.00e-99 355.00
IUUC-Mtr-058660 Medicago truncatula 56.64 0.00e+00 822.00
IUUC-Mla-058936 Melampsora laricipopulina 39.31 2.00e-113 402.00
IUUC-Mga-059866 Meleagris gallopavo 91.29 0.00e+00 1332.00
IUUC-Mvi-060455 Microbotryum violaceum 41.80 5.00e-143 501.00
IUUC-Mmr-061551 Microcebus murinus 91.20 0.00e+00 1391.00
IUUC-Mdo-062215 Monodelphis domestica 92.16 0.00e+00 1439.00
IUUC-Mmu-063402 Mus musculus 92.12 0.00e+00 1402.00
IUUC-Mac-064443 Musa acuminata 55.33 0.00e+00 836.00
IUUC-Mpu-066383 Mustela putorius furo 93.83 0.00e+00 1373.00
IUUC-Mlu-067450 Myotis lucifugus 90.58 0.00e+00 1380.00
IUUC-Nfi-068363 Neosartorya fischeri 37.95 4.00e-135 475.00
IUUC-Ncr-068950 Neurospora crassa 35.81 8.00e-119 421.00
IUUC-Nle-069606 Nomascus leucogenys 92.51 0.00e+00 1398.00
IUUC-Opr-070671 Ochotona princeps 80.93 5.00e-114 404.00
IUUC-Ont-071562 Oreochromis niloticus 79.03 0.00e+00 1228.00
IUUC-Oan-073299 Ornithorhynchus anatinus 87.91 0.00e+00 1350.00
IUUC-Ocu-074731 Oryctolagus cuniculus 91.98 0.00e+00 1415.00
IUUC-Oba-075198 Oryza barthii 55.98 0.00e+00 823.00
IUUC-Obr-076095 Oryza brachyantha 55.98 0.00e+00 824.00
IUUC-Ogl-077032 Oryza glaberrima 55.98 0.00e+00 824.00
IUUC-Ogu-078051 Oryza glumaepatula 55.24 0.00e+00 823.00
IUUC-Oin-079399 Oryza indica 59.73 0.00e+00 720.00
IUUC-Olo-080988 Oryza longistaminata 55.16 0.00e+00 813.00
IUUC-Ome-081600 Oryza meridionalis 55.16 0.00e+00 814.00
IUUC-Oni-082623 Oryza nivara 55.30 0.00e+00 815.00
IUUC-Opu-083762 Oryza punctata 55.18 0.00e+00 815.00
IUUC-Oru-084499 Oryza rufipogon 55.98 0.00e+00 823.00
IUUC-Ola-087157 Oryzias latipes 82.35 0.00e+00 1239.00
IUUC-Olu-087650 Ostreococcus lucimarinus 47.58 5.00e-179 620.00
IUUC-Oga-088416 Otolemur garnettii 79.97 0.00e+00 1217.00
IUUC-Oar-089346 Ovis aries 94.01 0.00e+00 1379.00
IUUC-Ptr-091177 Pan troglodytes 92.64 0.00e+00 1399.00
IUUC-Pan-092191 Papio anubis 92.67 0.00e+00 1400.00
IUUC-Psi-093773 Pelodiscus sinensis 82.30 0.00e+00 1268.00
IUUC-Pma-094678 Petromyzon marinus 78.06 0.00e+00 988.00
IUUC-Pno-094946 Phaeosphaeria nodorum 36.12 8.00e-111 394.00
IUUC-Ppa-095688 Physcomitrella patens 58.86 0.00e+00 890.00
IUUC-Pfo-096828 Poecilia formosa 82.57 0.00e+00 1246.00
IUUC-Pab-097622 Pongo abelii 92.12 0.00e+00 1392.00
IUUC-Pca-100391 Procavia capensis 83.97 0.00e+00 1003.00
IUUC-Ppe-101142 Prunus persica 57.09 0.00e+00 830.00
IUUC-Pva-102974 Pteropus vampyrus 94.71 0.00e+00 1130.00
IUUC-Pgr-103334 Puccinia graminis 33.41 5.00e-106 378.00
IUUC-Ptt-103903 Puccinia triticina 40.71 2.00e-95 343.00
IUUC-Pte-104167 Pyrenophora teres 35.65 2.00e-130 459.00
IUUC-Pyt-104736 Pyrenophora triticirepentis 35.36 2.00e-128 452.00
IUUC-Rno-105829 Rattus norvegicus 92.38 0.00e+00 1440.00
IUUC-Sha-106762 Sarcophilus harrisii 92.64 0.00e+00 1317.00
IUUC-Sja-107940 Schizosaccharomyces japonicus 33.29 2.00e-110 392.00
IUUC-Spo-108109 Schizosaccharomyces pombe 31.82 2.00e-105 376.00
IUUC-Ssl-108537 Sclerotinia sclerotiorum 37.89 1.00e-127 450.00
IUUC-Smo-109313 Selaginella moellendorffii 58.27 0.00e+00 889.00
IUUC-Sit-110626 Setaria italica 56.20 0.00e+00 816.00
IUUC-Sly-111497 Solanum lycopersicum 58.82 0.00e+00 848.00
IUUC-Sar-113581 Sorex araneus 72.42 0.00e+00 899.00
IUUC-Sbi-113931 Sorghum bicolor 56.20 0.00e+00 819.00
IUUC-Sre-114943 Sporisorium reilianum 38.06 2.00e-131 462.00
IUUC-Tgu-116961 Taeniopygia guttata 90.71 0.00e+00 1341.00
IUUC-Tru-118299 Takifugu rubripes 82.31 0.00e+00 1252.00
IUUC-Tni-120811 Tetraodon nigroviridis 80.63 0.00e+00 1221.00
IUUC-Tca-121626 Theobroma cacao 58.13 0.00e+00 834.00
IUUC-Tre-121907 Trichoderma reesei 39.23 2.00e-131 462.00
IUUC-Tvi-122568 Trichoderma virens 38.75 3.00e-131 462.00
IUUC-Tae-123442 Triticum aestivum 53.84 0.00e+00 822.00
IUUC-Tur-126032 Triticum urartu 56.20 0.00e+00 823.00
IUUC-Tme-127162 Tuber melanosporum 40.77 6.00e-140 491.00
IUUC-Tbe-127658 Tupaia belangeri 78.82 0.00e+00 1191.00
IUUC-Ttr-128326 Tursiops truncatus 88.64 0.00e+00 1179.00
IUUC-Uma-129531 Ustilago maydis 38.06 3.00e-113 402.00
IUUC-Vda-129701 Verticillium dahliae 39.51 5.00e-137 481.00
IUUC-Vpa-130217 Vicugna pacos 73.83 0.00e+00 1112.00
IUUC-Vvi-131133 Vitis vinifera 58.91 0.00e+00 854.00
IUUC-Xtr-132761 Xenopus tropicalis 82.33 0.00e+00 1286.00
IUUC-Xma-134149 Xiphophorus maculatus 82.68 0.00e+00 1255.00
IUUC-Yli-134576 Yarrowia lipolytica 32.05 3.00e-83 302.00
IUUC-Zma-135529 Zea mays 56.48 0.00e+00 822.00
Created Date 25-Jun-2017

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