iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090098

Ensembl Protein ID

ENSOARP00000002189.1

UniProt Accession

W5NVJ3; W5NVJ3_SHEEP

Genbank Protein ID

ENSOARP00000002189

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01114840

Gene Name

USP9X

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000002046.1	ENSOART00000002240.1	ENSOARP00000002189.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.70e-84	284.1	1557	1955

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle................kkkeklneenp............................. 42
           +GlkN g+tCYmNSv+Q+L++ip++r+ +l                 k         +                             
   Q: 1557 VGLKNAGATCYMNSVIQQLYMIPSIRNGILAiegtgsdvdddlsgdeK---------Qdnesnvdprddvfgypqqfedkpalskte 1634
           6******************************88888877776654431.........023333455677777777777777777777 PP
   S: 43   ..kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedksels 127
             ke +  +l++lq +f +l  s+ +++ pr ++k+++ + e ++  eq+Da Ef++ l+d+l+e+l                    
   Q: 1635 drKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGEPVNLREQHDALEFFNSLVDSLDEAL-------------------- 1701
           6677777************************************************************.................... PP
   S: 128  deaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkk 214
                 k   ++ ++s++++g++ +q +c+ c ++++ ee+f++l++++++++     +l d+Le+++k + leg+n+y+cekc+kk
   Q: 1702 ------KALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQ-----NLLDSLEQYVKGDLLEGANAYHCEKCNKK 1777
           ......67999******************************************.....9**************************** PP
   S: 215  qeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts......................peekqke..... 274
           ++++k+l +kklP+vL ++LkRf ++ e+++ +k+n+++efp+eLd++p+++                       +     +     
   Q: 1778 VDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAgvaklegdnvnpesqliqqneqS-----Dneaag 1859
           *****************************************************88888888888887777665442.....144566 PP
   S: 275  kkkYeLiavvvHsGslssGHYvayvknekgk......WllfdDskVtevkeeevleetg...........................s 328
           ++kY+L++v+vHsG++s+GHY++y+ +++g+      W++fdD  Vte+k+++ +e+++                           +
   Q: 1860 STKYRLVGVLVHSGQASGGHYYSYIIQRNGGdgernrWYKFDDGDVTECKMDDDEEMKNqcfggeymgevfdhmmkrmsyrrqkrwW 1946
           ***************************5444555556*******************9999*************************** PP
   S: 329  taYvlfYkr 337
           +aY+lfY+r
   Q: 1947 NAYILFYER 1955
           *******98 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MTATTRGSPV GGNDSQGQAP DGQSQPALQQ NQTSSPDSSN ENSPATPPDE QGQGDAPSQL 60
EDEEPAFPHT DLAKLDDMIN RPRWVVPVLP KGELEVLLEA AIDLSKKGLD VKSEACQRFF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCTTGGGCC TGGGATGCTC CCAGGGTCGG CCTTATCCCG GGACTGAGCC TTGGTTGTCG 60
CCTCCGCGTG TCTTGCTTCT TAAGAGAAGA CGCCTGTGTT GTGCGGTGAG TAGCCAGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005737--C:cytoplasm
GO:0030426--C:growth cone
GO:0016020--C:membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0048675--P:axon extension
GO:0030509--P:BMP signaling pathway
GO:0001764--P:neuron migration
GO:0016579--P:protein deubiquitination
GO:0007179--P:transforming growth factor beta receptor signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001640	Ailuropoda melanoleuca	98.21	0.00e+00	5019.00
IUUC-Apl-003592	Anas platyrhynchos	93.89	0.00e+00	4833.00
IUUC-Aca-004939	Anolis carolinensis	93.58	0.00e+00	4792.00
IUUC-Ame-011772	Astyanax mexicanus	88.32	0.00e+00	4551.00
IUUC-Bta-012775	Bos taurus	98.83	0.00e+00	5018.00
IUUC-Cja-019464	Callithrix jacchus	97.16	0.00e+00	4888.00
IUUC-Cfa-020569	Canis familiaris	98.87	0.00e+00	3235.00
IUUC-Csa-023405	Chlorocebus sabaeus	97.67	0.00e+00	4954.00
IUUC-Cho-024524	Choloepus hoffmanni	94.39	0.00e+00	804.00
IUUC-Cin-025551	Ciona intestinalis	63.50	2.00e-142	499.00
IUUC-Csv-025956	Ciona savignyi	53.66	0.00e+00	2498.00
IUUC-Dre-028329	Danio rerio	88.36	0.00e+00	4584.00
IUUC-Dno-028936	Dasypus novemcinctus	97.86	0.00e+00	5007.00
IUUC-Dor-030352	Dipodomys ordii	93.72	0.00e+00	2246.00
IUUC-Dme-032160	Drosophila melanogaster	47.79	0.00e+00	2174.00
IUUC-Ete-032287	Echinops telfairi	96.65	0.00e+00	2773.00
IUUC-Eca-033352	Equus caballus	98.52	0.00e+00	5058.00
IUUC-Eeu-034907	Erinaceus europaeus	86.98	0.00e+00	1847.00
IUUC-Fca-035458	Felis catus	98.72	0.00e+00	5052.00
IUUC-Fal-036924	Ficedula albicollis	93.71	0.00e+00	4738.00
IUUC-Gmo-039578	Gadus morhua	87.92	0.00e+00	4489.00
IUUC-Gga-040978	Gallus gallus	93.97	0.00e+00	4838.00
IUUC-Gac-041970	Gasterosteus aculeatus	89.69	0.00e+00	4571.00
IUUC-Ggo-045575	Gorilla gorilla	98.64	0.00e+00	5021.00
IUUC-Hsa-046295	Homo sapiens	98.72	0.00e+00	5025.00
IUUC-Itr-048768	Ictidomys tridecemlineatus	97.74	0.00e+00	5001.00
IUUC-Lch-050493	Latimeria chalumnae	91.65	0.00e+00	4644.00
IUUC-Loc-052667	Lepisosteus oculatus	89.99	0.00e+00	4695.00
IUUC-Laf-054094	Loxodonta africana	98.79	0.00e+00	5046.00
IUUC-Mcc-054861	Macaca mulatta	96.54	0.00e+00	4931.00
IUUC-Meu-056849	Macropus eugenii	83.43	0.00e+00	1434.00
IUUC-Mga-060159	Meleagris gallopavo	93.78	0.00e+00	4830.00
IUUC-Mmr-060732	Microcebus murinus	97.40	0.00e+00	5001.00
IUUC-Mdo-062274	Monodelphis domestica	94.28	0.00e+00	4901.00
IUUC-Mmu-064056	Mus musculus	96.93	0.00e+00	4973.00
IUUC-Mpu-066669	Mustela putorius furo	98.25	0.00e+00	5023.00
IUUC-Mlu-067516	Myotis lucifugus	97.36	0.00e+00	4977.00
IUUC-Nle-069664	Nomascus leucogenys	98.53	0.00e+00	3665.00
IUUC-Opr-070185	Ochotona princeps	87.53	0.00e+00	796.00
IUUC-Ont-072119	Oreochromis niloticus	90.16	0.00e+00	4606.00
IUUC-Oan-073154	Ornithorhynchus anatinus	93.81	0.00e+00	4880.00
IUUC-Ocu-074485	Oryctolagus cuniculus	98.68	0.00e+00	5079.00
IUUC-Ola-086350	Oryzias latipes	89.34	0.00e+00	4504.00
IUUC-Oga-088328	Otolemur garnettii	98.21	0.00e+00	5090.00
IUUC-Pan-091741	Papio anubis	98.73	0.00e+00	3806.00
IUUC-Psi-093040	Pelodiscus sinensis	93.78	0.00e+00	4820.00
IUUC-Pfo-096871	Poecilia formosa	89.08	0.00e+00	4575.00
IUUC-Pab-098374	Pongo abelii	97.70	0.00e+00	4949.00
IUUC-Pca-100801	Procavia capensis	89.71	0.00e+00	2431.00
IUUC-Pva-102992	Pteropus vampyrus	93.13	0.00e+00	2431.00
IUUC-Rno-105377	Rattus norvegicus	97.12	0.00e+00	4982.00
IUUC-Sha-106648	Sarcophilus harrisii	91.64	0.00e+00	4724.00
IUUC-Smo-108879	Selaginella moellendorffii	28.11	0.00e+00	815.00
IUUC-Sar-113729	Sorex araneus	94.99	0.00e+00	3177.00
IUUC-Ssc-116261	Sus scrofa	92.81	0.00e+00	4825.00
IUUC-Tgu-117126	Taeniopygia guttata	93.85	0.00e+00	4830.00
IUUC-Tru-117676	Takifugu rubripes	89.37	0.00e+00	4579.00
IUUC-Tsy-119209	Tarsius syrichta	86.38	0.00e+00	2674.00
IUUC-Tni-120207	Tetraodon nigroviridis	85.12	0.00e+00	2038.00
IUUC-Tbe-128033	Tupaia belangeri	97.42	0.00e+00	1049.00
IUUC-Ttr-128742	Tursiops truncatus	97.08	0.00e+00	4954.00
IUUC-Vpa-130581	Vicugna pacos	94.98	0.00e+00	4809.00
IUUC-Xtr-132145	Xenopus tropicalis	91.80	0.00e+00	4753.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence