iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049660

Ensembl Protein ID

ENSLACP00000006306.1

UniProt Accession

H3A9I5; H3A9I5_LATCH

Genbank Protein ID

ENSLACP00000006306

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01183955

Gene Name

LOC102365523

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000005595.1	ENSLACT00000006359.1	ENSLACP00000006306.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-19	70.2	568	922

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgyeq 89
           G++ ++N+CY++++L c+++++++ + +l + + k +e++++++   l +++ + +++    + +k+++ r++l+a ++       +e+
   Q: 568  GIQGHCNSCYLDATLFCMFAFSSVLDTILLRPQDKNDEDSYSQTRDLLRTEIVNPLRKNGyVCATKVMALRKILEAGGQSTGF--LTEE 654
           99****************************899999999999999999999*999999987999************9988875..6899 PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlk....sqikclecdnvs.sreepfldls 173
           +D +Efl+ l++ l+ e      k ++ +++ +++   ++  ekk++ n   +++l+++++     + +  ++c  v+  r+ +++++ 
   Q: 655  KDPEEFLNKLFQVLKVEP---LLKIRSATQKPQDCIFYQIFMEKKQSVNIPSVQQLLEWSFVnsdlKFTEAPSCFIVQmPRFGKNFKMF 740
           ***************988...678888888889999*************************943333466899****999999988888 PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenk.yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ld 260
             +    e    +++d+Le+  +e++++++   ++c++c+++++ +   ++k+ + v     k +  +++++++++  +++ +p+e  d
   Q: 741  STILPTLEL---DITDLLEDTPRECSICQSLSmVECRNCYEDSDITPG-RIKQYCSV---CSKQV--HQHRNRKSHDPRNLLLPKElQD 820
           888877777...***************9986549*******9985554.77776665...55666..4556777778889999999557 PP
   S: 261  lspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn..ekgkWllfdD.............skVtevke.eevleetg...... 327
            ++f  s       +++ eL+av++ +      HYva+vk    + +Wl fd               +V++++e +e l++++      
   Q: 821  CNEFPGSIP-----HQTMELSAVLCIET----SHYVAFVKYgpADTDWLFFDSmadrkggqsgfniPQVSPCPEvAEYLKMSAdelrdl 900
           777777733.....89*********999....9********654555999999999999999999999999987688999888999999 PP
   S: 328  .............staYvlfYk 336
                        ++aY+++Y+
   Q: 901  dpksmqgcvrrllCDAYMCMYH 922
           9999999999***********7 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MFILTTDYVG NDKLEGPVRI LKGSLLYLAK EEPHQPGVRG PAAVERFWVK VLDTEDLLKV 60
DTRAVREVSE RAAGLLEAVT NLDERLALFG NERRLKRLGQ IEKGDSVRVQ ISSSSGEKVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTAACTTTG GTATGGCCTT CTCTTGCTCT CTCTACCTAC CTATTTATTA CTCATTTTCA 60
TCAGGAGTGA AGAAAAGGAA CATTTCTTCT TCTGAAGCAA GGAAACAGGC TGAAAATAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000938--CAP-Gly_domain
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50245--CAP_GLY_2
PS00972--USP_1
PS50235--USP_3

Pfam

PF01302--CAP_GLY
PF00443--UCH

SMART

SM01052--CAP_GLY

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cel-018528	Caenorhabditis elegans	37.53	6.00e-58	219.00
IUUC-Cin-025179	Ciona intestinalis	42.98	5.00e-106	377.00
IUUC-Dme-032159	Drosophila melanogaster	44.16	3.00e-112	399.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence