iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-025899

UUCD1 version

UUC-CiS-00004

Ensembl Protein ID

ENSCSAVP00000005614.1

UniProt Accession

H2YJW5; H2YJW5_CIOSA

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000003351.1	ENSCSAVT00000005684.1	ENSCSAVP00000005609.1
ENSCSAVG00000003351.1	ENSCSAVT00000005686.1	ENSCSAVP00000005611.1
ENSCSAVG00000003351.1	ENSCSAVT00000005687.1	ENSCSAVP00000005612.1
ENSCSAVG00000003351.1	ENSCSAVT00000005688.1	ENSCSAVP00000005613.1
ENSCSAVG00000003351.1	ENSCSAVT00000005689.1	ENSCSAVP00000005614.1
ENSCSAVG00000003351.1	ENSCSAVT00000005690.1	ENSCSAVP00000005615.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.10e-11	42.1	5	59

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            ++ ++d++  ++ +L++kkGd ++v+ + + d +W k+ k+ +g +G++P n+++k
   Q: 5    ECEGIFDFNTGKKTDLQFKKGDSITVM-QRTRDPNWYKA-KNEKGEQGMVPINYIVK 59
           5899**********************9.***********.6*************986 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

APGTECEGIF DFNTGKKTDL QFKKGDSITV MQRTRDPNWY KAKNEKGEQG MVPINYIVKN 60
DVGYKPPTEC PNGTTIEPRG VIPPPTYRRE LAVRHKEVKL TAMPWFHGKI SRSAAEDLLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATCATTATT CCATTCATCA GGTGCGATAA TCCATCATAA TAAATAGTTG AATTAATTAG 60
TTAAACCAAT TCGTTTTCTA CGTTTTCCAG AAAAATATTA ATCTTTAATG GAAGAGCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004391	Anolis carolinensis	50.94	6.00e-138	482.00
IUUC-Cin-025513	Ciona intestinalis	79.12	0.00e+00	779.00
IUUC-Fal-037215	Ficedula albicollis	51.99	3.00e-139	486.00
IUUC-Gmo-039103	Gadus morhua	49.48	4.00e-133	466.00
IUUC-Gga-040506	Gallus gallus	51.99	3.00e-139	486.00
IUUC-Loc-052586	Lepisosteus oculatus	50.94	3.00e-135	473.00
IUUC-Meu-056387	Macropus eugenii	51.57	1.00e-138	484.00
IUUC-Mga-060040	Meleagris gallopavo	50.31	3.00e-133	466.00
IUUC-Mdo-061871	Monodelphis domestica	51.57	1.00e-138	484.00
IUUC-Ont-072457	Oreochromis niloticus	51.18	2.00e-135	474.00
IUUC-Ola-087105	Oryzias latipes	50.53	2.00e-135	473.00
IUUC-Oga-087928	Otolemur garnettii	51.36	2.00e-136	477.00
IUUC-Pfo-096126	Poecilia formosa	50.97	2.00e-135	473.00
IUUC-Sha-106987	Sarcophilus harrisii	51.57	6.00e-139	485.00
IUUC-Tru-118712	Takifugu rubripes	50.32	8.00e-134	468.00
IUUC-Tni-119856	Tetraodon nigroviridis	50.32	2.00e-133	466.00
IUUC-Tae-124889	Triticum aestivum	29.70	1.00e-19	90.50
IUUC-Xtr-132763	Xenopus tropicalis	50.31	4.00e-131	459.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence