iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011534

Ensembl Protein ID

ENSAMXP00000012200.1

UniProt Accession

W5KX88; W5KX88_ASTMX

Genbank Protein ID

ENSAMXP00000012200

Protein Name

Eukaryotic translation initiation factor 3 subunit I; Eukaryotic translation initiation factor 3 subunit 2; eIF-3-beta; eIF3 p36

Genbank Nucleotide ID

APWO01088077

Gene Name

eif3i; EIF3I; EIF3S2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000011863.1	ENSAMXT00000012200.1	ENSAMXP00000012200.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.20e-19	67.4	50	87

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcl..afsd.tllvsGsdDgtikvWDlrtgvll 36
           gH++ v+c+  ++ d + +++Gs D+++++WD  tg++l
   Q: 50   GHSGAVWCVdvDW-DtKNVLTGSADNSCRLWDCETGKQL 87
           8*******63377.4488*****************9987 PP

Organism

Astyanax mexicanus

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MKPILLQGHE RSLTQIKYNR EGDLLFSVAK DQFANVWYSV NGERLGTYNG HSGAVWCVDV 60
DWDTKNVLTG SADNSCRLWD CETGKQLAML ETNSAVRTCG FDFSGNIIMF STDKQMGYQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAAAGACT GTGAACCTTT ATTTTGAAGT GGTTGACGGG GCGCAGGCGG TAGTCGCGCC 60
CTCTGTCGGT CGGTTCGGTC CTTGCGCGGT GCCGGTGATA CACGCGGCTG GTGTGTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR027525--eIF3i
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0001889--P:liver development
GO:0006446--P:regulation of translational initiation
GO:0002040--P:sprouting angiogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	56.64	2.00e-34	139.00
IUUC-Aml-001321	Ailuropoda melanoleuca	80.98	3.00e-167	580.00
IUUC-Atr-002468	Amborella trichopoda	50.00	5.00e-53	200.00
IUUC-Apl-003841	Anas platyrhynchos	82.82	4.00e-170	590.00
IUUC-Aca-005123	Anolis carolinensis	81.96	3.00e-169	587.00
IUUC-Aly-006532	Arabidopsis lyrata	46.65	3.00e-86	311.00
IUUC-Ath-007094	Arabidopsis thaliana	45.73	1.00e-87	316.00
IUUC-Ago-008000	Ashbya gossypii	43.81	8.00e-83	300.00
IUUC-Acl-008098	Aspergillus clavatus	51.81	2.00e-99	355.00
IUUC-Afl-008494	Aspergillus flavus	51.22	9.00e-101	359.00
IUUC-Afu-009080	Aspergillus fumigatus	51.51	1.00e-100	359.00
IUUC-Ani-009230	Aspergillus nidulans	51.83	2.00e-101	362.00
IUUC-Aor-010114	Aspergillus oryzae	51.22	9.00e-101	359.00
IUUC-Ate-010285	Aspergillus terreus	51.83	3.00e-102	364.00
IUUC-Bgr-012121	Blumeria graminis	47.88	5.00e-90	324.00
IUUC-Bta-013143	Bos taurus	81.04	6.00e-168	583.00
IUUC-Bci-013950	Botrytis cinerea	50.75	3.00e-98	351.00
IUUC-Bdi-015019	Brachypodium distachyon	47.26	4.00e-89	321.00
IUUC-Bol-015709	Brassica oleracea	43.94	2.00e-82	300.00
IUUC-Bra-017760	Brassica rapa	43.94	6.00e-83	301.00
IUUC-Cel-018226	Caenorhabditis elegans	43.08	3.00e-81	295.00
IUUC-Cja-019741	Callithrix jacchus	81.04	2.00e-168	584.00
IUUC-Cfa-021204	Canis familiaris	81.29	8.00e-168	582.00
IUUC-Cpo-021661	Cavia porcellus	81.29	9.00e-168	582.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	42.72	2.00e-79	288.00
IUUC-Csa-024038	Chlorocebus sabaeus	81.04	2.00e-168	584.00
IUUC-Cin-025597	Ciona intestinalis	57.58	2.00e-115	408.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	49.24	1.00e-92	333.00
IUUC-Cne-026838	Cryptococcus neoformans	47.88	1.00e-92	332.00
IUUC-Cme-027304	Cyanidioschyzon merolae	45.79	2.00e-83	301.00
IUUC-Dre-028567	Danio rerio	91.13	0.00e+00	643.00
IUUC-Dno-029171	Dasypus novemcinctus	81.29	5.00e-168	583.00
IUUC-Dor-030257	Dipodomys ordii	69.66	2.00e-72	265.00
IUUC-Dse-031191	Dothistroma septosporum	48.67	4.00e-92	331.00
IUUC-Dme-031879	Drosophila melanogaster	60.37	4.00e-120	424.00
IUUC-Ete-032336	Echinops telfairi	75.93	9.00e-103	365.00
IUUC-Eca-033259	Equus caballus	80.98	2.00e-167	581.00
IUUC-Eeu-035153	Erinaceus europaeus	61.07	8.00e-49	187.00
IUUC-Fca-036489	Felis catus	80.98	2.00e-167	581.00
IUUC-Fal-037485	Ficedula albicollis	83.44	7.00e-171	592.00
IUUC-Fox-037860	Fusarium oxysporum	48.78	1.00e-94	339.00
IUUC-Fso-038188	Fusarium solani	48.78	2.00e-92	332.00
IUUC-Gmo-039311	Gadus morhua	88.65	0.00e+00	625.00
IUUC-Ggr-040045	Gaeumannomyces graminis	49.85	1.00e-96	346.00
IUUC-Gga-040645	Gallus gallus	80.90	9.00e-169	585.00
IUUC-Gac-042086	Gasterosteus aculeatus	89.91	0.00e+00	626.00
IUUC-Gma-043246	Glycine max	46.20	2.00e-88	319.00
IUUC-Ggo-045578	Gorilla gorilla	81.04	2.00e-168	584.00
IUUC-Hsa-046734	Homo sapiens	81.04	2.00e-168	584.00
IUUC-Hvu-047553	Hordeum vulgare	46.34	4.00e-88	317.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	80.67	3.00e-167	580.00
IUUC-Kpa-049325	Komagataella pastoris	43.37	2.00e-84	305.00
IUUC-Lch-049620	Latimeria chalumnae	82.33	6.00e-155	539.00
IUUC-Lpe-051338	Leersia perrieri	45.22	8.00e-80	290.00
IUUC-Loc-052094	Lepisosteus oculatus	82.77	4.00e-164	570.00
IUUC-Lma-053047	Leptosphaeria maculans	48.18	3.00e-92	331.00
IUUC-Laf-053801	Loxodonta africana	80.62	1.00e-163	568.00
IUUC-Mcc-055498	Macaca mulatta	70.95	2.00e-138	484.00
IUUC-Meu-056729	Macropus eugenii	74.09	1.00e-149	522.00
IUUC-Mor-057025	Magnaporthe oryzae	48.94	3.00e-93	335.00
IUUC-Mpo-057511	Magnaporthe poae	50.15	1.00e-95	343.00
IUUC-Mtr-058051	Medicago truncatula	46.20	4.00e-88	317.00
IUUC-Mla-059061	Melampsora laricipopulina	47.85	4.00e-86	311.00
IUUC-Mga-059229	Meleagris gallopavo	82.01	1.00e-167	582.00
IUUC-Mvi-060399	Microbotryum violaceum	46.87	8.00e-83	300.00
IUUC-Mmr-060764	Microcebus murinus	81.35	9.00e-169	585.00
IUUC-Mdo-062088	Monodelphis domestica	80.73	3.00e-166	577.00
IUUC-Mmu-064304	Mus musculus	81.35	2.00e-168	584.00
IUUC-Mac-065520	Musa acuminata	47.53	6.00e-90	323.00
IUUC-Mpu-066340	Mustela putorius furo	80.98	2.00e-167	581.00
IUUC-Mlu-067111	Myotis lucifugus	80.98	9.00e-168	582.00
IUUC-Nfi-068478	Neosartorya fischeri	51.51	1.00e-100	359.00
IUUC-Ncr-068820	Neurospora crassa	49.40	4.00e-94	338.00
IUUC-Nle-069903	Nomascus leucogenys	80.98	7.00e-168	582.00
IUUC-Opr-070221	Ochotona princeps	79.51	6.00e-163	566.00
IUUC-Ont-071765	Oreochromis niloticus	91.74	0.00e+00	639.00
IUUC-Oan-073660	Ornithorhynchus anatinus	81.02	9.00e-151	525.00
IUUC-Ocu-074039	Oryctolagus cuniculus	80.98	1.00e-167	582.00
IUUC-Oba-075395	Oryza barthii	40.12	2.00e-70	259.00
IUUC-Obr-076334	Oryza brachyantha	43.28	1.00e-79	290.00
IUUC-Ogl-077060	Oryza glaberrima	46.04	5.00e-86	310.00
IUUC-Ogu-078207	Oryza glumaepatula	46.04	6.00e-86	310.00
IUUC-Oin-079878	Oryza indica	46.20	1.00e-86	312.00
IUUC-Olo-080677	Oryza longistaminata	39.69	5.00e-78	284.00
IUUC-Ome-081228	Oryza meridionalis	34.02	3.00e-34	138.00
IUUC-Oni-082411	Oryza nivara	40.06	4.00e-71	261.00
IUUC-Opu-083136	Oryza punctata	46.34	9.00e-87	313.00
IUUC-Oru-084916	Oryza rufipogon	44.97	4.00e-84	304.00
IUUC-Osa-085776	Oryza sativa	46.20	6.00e-87	313.00
IUUC-Ola-087053	Oryzias latipes	89.60	0.00e+00	627.00
IUUC-Olu-087602	Ostreococcus lucimarinus	45.82	6.00e-87	313.00
IUUC-Oga-088154	Otolemur garnettii	80.67	9.00e-167	579.00
IUUC-Oar-089915	Ovis aries	80.98	3.00e-167	580.00
IUUC-Ptr-091124	Pan troglodytes	64.60	9.00e-123	432.00
IUUC-Pan-092035	Papio anubis	81.04	2.00e-168	584.00
IUUC-Psi-094096	Pelodiscus sinensis	79.00	2.00e-106	377.00
IUUC-Pno-094988	Phaeosphaeria nodorum	44.95	3.00e-81	295.00
IUUC-Ppa-095949	Physcomitrella patens	48.17	4.00e-92	331.00
IUUC-Pfo-096101	Poecilia formosa	89.91	0.00e+00	630.00
IUUC-Pab-097726	Pongo abelii	81.04	2.00e-168	584.00
IUUC-Pop-099617	Populus trichocarpa	47.42	2.00e-90	325.00
IUUC-Pca-101014	Procavia capensis	81.04	2.00e-168	584.00
IUUC-Ppe-101320	Prunus persica	46.50	5.00e-87	314.00
IUUC-Pva-102789	Pteropus vampyrus	71.56	2.00e-141	494.00
IUUC-Pgr-103479	Puccinia graminis	47.85	2.00e-85	308.00
IUUC-Ptt-103981	Puccinia triticina	47.37	1.00e-86	312.00
IUUC-Pte-104278	Pyrenophora teres	48.48	3.00e-91	328.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	48.48	3.00e-91	328.00
IUUC-Rno-105867	Rattus norvegicus	64.85	1.00e-121	429.00
IUUC-Sce-106251	Saccharomyces cerevisiae	45.95	1.00e-84	306.00
IUUC-Sha-107039	Sarcophilus harrisii	80.73	2.00e-166	578.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	50.46	1.00e-94	339.00
IUUC-Spo-108314	Schizosaccharomyces pombe	49.39	6.00e-93	333.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	49.85	2.00e-97	348.00
IUUC-Smo-108728	Selaginella moellendorffii	47.42	1.00e-87	316.00
IUUC-Sit-110801	Setaria italica	45.12	1.00e-85	309.00
IUUC-Sly-111326	Solanum lycopersicum	47.42	7.00e-90	323.00
IUUC-Stu-112458	Solanum tuberosum	48.02	1.00e-89	323.00
IUUC-Sbi-114063	Sorghum bicolor	45.73	7.00e-86	310.00
IUUC-Sre-115096	Sporisorium reilianum	47.46	7.00e-86	310.00
IUUC-Ssc-116080	Sus scrofa	81.04	5.00e-168	583.00
IUUC-Tgu-116988	Taeniopygia guttata	83.44	1.00e-170	592.00
IUUC-Tru-118766	Takifugu rubripes	92.05	0.00e+00	641.00
IUUC-Tni-120197	Tetraodon nigroviridis	92.35	0.00e+00	643.00
IUUC-Tca-121316	Theobroma cacao	45.59	2.00e-87	315.00
IUUC-Tre-122097	Trichoderma reesei	50.61	7.00e-96	343.00
IUUC-Tvi-122442	Trichoderma virens	50.61	1.00e-96	345.00
IUUC-Tae-125800	Triticum aestivum	46.34	4.00e-88	318.00
IUUC-Tur-126334	Triticum urartu	39.63	1.00e-67	249.00
IUUC-Tme-127038	Tuber melanosporum	52.11	1.00e-101	362.00
IUUC-Ttr-128659	Tursiops truncatus	76.15	2.00e-144	504.00
IUUC-Uma-129464	Ustilago maydis	47.46	3.00e-85	308.00
IUUC-Vda-129841	Verticillium dahliae	51.83	1.00e-97	349.00
IUUC-Vvi-131076	Vitis vinifera	46.50	1.00e-88	319.00
IUUC-Xtr-132395	Xenopus tropicalis	83.18	5.00e-172	596.00
IUUC-Xma-133383	Xiphophorus maculatus	89.60	0.00e+00	628.00
IUUC-Yli-134586	Yarrowia lipolytica	47.71	4.00e-81	294.00
IUUC-Zma-135904	Zea mays	46.04	1.00e-86	313.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence