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Tag Content
UUCD2 ID IUUC-Dre-027578
UUCD1 version UUC-DaR-01390
Ensembl Protein ID ENSDARP00000128713.2
UniProt Accession X1WER2; UBA5_DANRE
Genbank Protein ID ENSDARP00000128713
Protein Name Ubiquitin-like modifier-activating enzyme 5
Genbank Nucleotide ID CR381660
Gene Name uba5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000063588.7 ENSDART00000093046.5 ENSDARP00000087478.5
ENSDARG00000063588.7 ENSDART00000157200.2 ENSDARP00000128713.2
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E1 82.35 6.00e-164 574.00 IUUC-Hsa-046777
Active Site
Position(s) Description Evidence
246 Glycyl thioester intermediate {ECO:0000250|UniProtKB:Q9GZZ9}
Organism Danio rerio
Functional Description
(View)

Functional Description


     E1-like enzyme which activates ufm1 and sumo2.
 E1-like enzyme which activates ufm1 and sumo2.
Protein Sequence
(Fasta)
MATVEELKLR IRELENELIK SKQKQSDAEH NIRPKIEQMS AEVVDSNPYS RLMALKRMGI 60
VQDYEKIRSF AVAVVGVGGV GSVTAEMLTR CGIGKLLLFD YDKVELANMN RLFFQPHQAG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-027578|E1,E1_ThiF|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGCGGTATTC ATTCACTGTG GGAACTTTAG TTCCTTGGTG TTGGTTGTTG CACTCCGGGC 60
TCAATATCGA GAGACACTCA TCCTCGCCAG CTGATTTGTA ACAGTGCAGA CGTGTACATG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-027578|E1,E1_ThiF|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
Interpro

IPR029752--D-isomer_DH_CS1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
PROSITE

PS00065--D_2_HYDROXYACID_DH_1
Pfam

PF00899--ThiF
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0008641--F:small protein activating enzyme activity
GO:0040011--P:locomotion
GO:0007626--P:locomotory behavior
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001324 Ailuropoda melanoleuca 83.56 2.00e-165 574.00
IUUC-Atr-002660 Amborella trichopoda 56.95 1.00e-111 396.00
IUUC-Apl-003722 Anas platyrhynchos 87.38 2.00e-161 561.00
IUUC-Aca-004584 Anolis carolinensis 81.05 2.00e-163 568.00
IUUC-Aly-005881 Arabidopsis lyrata 58.17 2.00e-112 399.00
IUUC-Ath-007286 Arabidopsis thaliana 61.16 3.00e-116 412.00
IUUC-Ame-011679 Astyanax mexicanus 91.18 1.00e-160 558.00
IUUC-Bta-012517 Bos taurus 83.29 2.00e-167 582.00
IUUC-Bdi-014894 Brachypodium distachyon 62.68 3.00e-114 405.00
IUUC-Bol-016054 Brassica oleracea 60.34 1.00e-115 410.00
IUUC-Bra-016708 Brassica rapa 61.34 7.00e-117 414.00
IUUC-Cel-018424 Caenorhabditis elegans 71.91 7.00e-125 440.00
IUUC-Cja-019825 Callithrix jacchus 82.46 2.00e-125 441.00
IUUC-Cfa-021160 Canis familiaris 78.25 2.00e-166 578.00
IUUC-Cpo-022255 Cavia porcellus 79.35 5.00e-165 573.00
IUUC-Csa-023827 Chlorocebus sabaeus 79.30 2.00e-173 602.00
IUUC-Cho-025078 Choloepus hoffmanni 77.72 2.00e-159 555.00
IUUC-Cin-025217 Ciona intestinalis 70.81 5.00e-150 523.00
IUUC-Dno-029330 Dasypus novemcinctus 82.64 2.00e-165 575.00
IUUC-Dor-030425 Dipodomys ordii 68.32 1.00e-95 343.00
IUUC-Dme-031645 Drosophila melanogaster 62.32 2.00e-129 455.00
IUUC-Ete-032912 Echinops telfairi 70.68 1.00e-41 164.00
IUUC-Eca-033247 Equus caballus 83.84 9.00e-168 583.00
IUUC-Eeu-034472 Erinaceus europaeus 83.71 3.00e-160 557.00
IUUC-Fca-035684 Felis catus 83.70 6.00e-167 580.00
IUUC-Fal-037654 Ficedula albicollis 83.15 2.00e-168 584.00
IUUC-Gmo-039449 Gadus morhua 68.87 4.00e-138 484.00
IUUC-Gga-041051 Gallus gallus 83.56 3.00e-168 584.00
IUUC-Gac-042325 Gasterosteus aculeatus 86.35 0.00e+00 689.00
IUUC-Gma-043136 Glycine max 56.97 2.00e-119 422.00
IUUC-Ggo-044414 Gorilla gorilla 79.55 5.00e-168 583.00
IUUC-Hsa-046777 Homo sapiens 79.80 2.00e-170 591.00
IUUC-Hvu-047549 Hordeum vulgare 60.50 4.00e-95 341.00
IUUC-Itr-048175 Ictidomys tridecemlineatus 83.97 1.00e-166 579.00
IUUC-Lch-050142 Latimeria chalumnae 80.84 0.00e+00 630.00
IUUC-Lpe-050769 Leersia perrieri 65.96 7.00e-101 360.00
IUUC-Loc-052405 Lepisosteus oculatus 87.88 1.00e-177 615.00
IUUC-Laf-054152 Loxodonta africana 78.30 7.00e-167 580.00
IUUC-Mcc-055618 Macaca mulatta 84.20 1.00e-157 548.00
IUUC-Meu-056486 Macropus eugenii 86.14 1.00e-162 566.00
IUUC-Mtr-057871 Medicago truncatula 59.84 2.00e-119 422.00
IUUC-Mga-059284 Meleagris gallopavo 83.56 1.00e-167 582.00
IUUC-Mmr-061242 Microcebus murinus 81.82 5.00e-169 587.00
IUUC-Mdo-063034 Monodelphis domestica 83.20 3.00e-168 585.00
IUUC-Mmu-064322 Mus musculus 79.03 9.00e-162 563.00
IUUC-Mac-065128 Musa acuminata 61.54 4.00e-70 263.00
IUUC-Mpu-066438 Mustela putorius furo 83.29 8.00e-165 573.00
IUUC-Mlu-067578 Myotis lucifugus 84.11 2.00e-166 578.00
IUUC-Nle-069542 Nomascus leucogenys 83.70 2.00e-167 582.00
IUUC-Opr-070710 Ochotona princeps 77.78 1.00e-166 579.00
IUUC-Ont-072067 Oreochromis niloticus 89.61 0.00e+00 645.00
IUUC-Oan-073593 Ornithorhynchus anatinus 84.94 2.00e-166 578.00
IUUC-Ocu-073964 Oryctolagus cuniculus 76.31 3.00e-163 567.00
IUUC-Oba-075476 Oryza barthii 61.40 6.00e-113 400.00
IUUC-Obr-076517 Oryza brachyantha 61.52 2.00e-112 399.00
IUUC-Ogu-078664 Oryza glumaepatula 61.70 2.00e-113 402.00
IUUC-Olo-081012 Oryza longistaminata 61.40 7.00e-113 400.00
IUUC-Ome-081129 Oryza meridionalis 61.40 6.00e-113 400.00
IUUC-Oni-082265 Oryza nivara 61.42 7.00e-112 397.00
IUUC-Opu-084121 Oryza punctata 61.40 6.00e-113 400.00
IUUC-Oru-084451 Oryza rufipogon 59.73 8.00e-98 350.00
IUUC-Osa-086132 Oryza sativa 61.40 6.00e-113 400.00
IUUC-Ola-086842 Oryzias latipes 87.47 2.00e-175 608.00
IUUC-Oga-088160 Otolemur garnettii 83.97 3.00e-164 571.00
IUUC-Oar-089362 Ovis aries 83.01 1.00e-168 585.00
IUUC-Ptr-091256 Pan troglodytes 79.55 1.00e-170 592.00
IUUC-Pan-092913 Papio anubis 80.05 1.00e-164 572.00
IUUC-Psi-093740 Pelodiscus sinensis 87.58 3.00e-157 547.00
IUUC-Pma-094485 Petromyzon marinus 87.89 8.00e-113 399.00
IUUC-Ppa-095673 Physcomitrella patens 61.05 1.00e-114 406.00
IUUC-Pfo-096196 Poecilia formosa 87.73 0.00e+00 652.00
IUUC-Pab-098449 Pongo abelii 79.30 6.00e-172 596.00
IUUC-Pop-099049 Populus trichocarpa 58.61 2.00e-111 395.00
IUUC-Pca-100917 Procavia capensis 80.33 2.00e-105 376.00
IUUC-Ppe-101797 Prunus persica 56.35 3.00e-118 418.00
IUUC-Pva-102852 Pteropus vampyrus 83.42 6.00e-168 583.00
IUUC-Rno-105213 Rattus norvegicus 79.03 7.00e-162 563.00
IUUC-Sha-107569 Sarcophilus harrisii 76.77 7.00e-169 586.00
IUUC-Smo-109146 Selaginella moellendorffii 62.82 4.00e-115 408.00
IUUC-Sit-109794 Setaria italica 64.09 3.00e-113 402.00
IUUC-Sly-111622 Solanum lycopersicum 58.84 3.00e-115 408.00
IUUC-Stu-112522 Solanum tuberosum 57.04 1.00e-114 406.00
IUUC-Sar-113045 Sorex araneus 70.18 4.00e-147 514.00
IUUC-Sbi-113861 Sorghum bicolor 60.11 3.00e-112 398.00
IUUC-Ssc-115290 Sus scrofa 82.62 3.00e-140 491.00
IUUC-Tgu-117125 Taeniopygia guttata 83.33 2.00e-169 588.00
IUUC-Tru-118041 Takifugu rubripes 87.34 0.00e+00 654.00
IUUC-Tsy-119300 Tarsius syrichta 76.00 2.00e-134 472.00
IUUC-Tni-120310 Tetraodon nigroviridis 86.05 1.00e-174 605.00
IUUC-Tca-121405 Theobroma cacao 57.59 5.00e-115 407.00
IUUC-Tae-123656 Triticum aestivum 59.84 2.00e-113 402.00
IUUC-Tur-125985 Triticum urartu 60.66 5.00e-114 404.00
IUUC-Tbe-127478 Tupaia belangeri 77.24 5.00e-134 470.00
IUUC-Ttr-128169 Tursiops truncatus 82.40 2.00e-121 428.00
IUUC-Vpa-130508 Vicugna pacos 78.29 9.00e-139 486.00
IUUC-Vvi-131252 Vitis vinifera 56.85 6.00e-116 410.00
IUUC-Xtr-132776 Xenopus tropicalis 83.92 1.00e-169 588.00
IUUC-Xma-133110 Xiphophorus maculatus 88.51 0.00e+00 659.00
Created Date 25-Jun-2017

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