iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060157

UUCD1 version

UUC-MeG-00862

Ensembl Protein ID

ENSMGAP00000007257.2

UniProt Accession

G1N5L4; G1N5L4_MELGA

Protein Name

Uncharacterized protein

Gene Name

USP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000007125.2	ENSMGAT00000008026.2	ENSMGAP00000007257.2
ENSMGAG00000007125.2	ENSMGAT00000020339.1	ENSMGAP00000018573.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.80e-67	227.7	426	806

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l+++  +   ++++++ +++++++s+ +l++e++      k k+              a++p+
   Q: 426  GLINKGNWCYINATLQALVACPPMYHLMKS-IPMY-SKSQRPCTSTPMIDSFVRLMNEFTnmpvppKAKQAlgdkivrdirpgaAFEPT 512
           9*****************************.3333.34455899***************8777664333337888889999999***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk..................eknkpkeeeeeedkselsde........aeek 133
            +++ l  +++++s + +q+Da+E+l f+l++l+ee+                    e ++  eeee++++ e s++        +   
   Q: 513  YIYRLLTVIKSSLSeKGRQEDAEEYLGFILNGLHEEMLTlkkllsphneklsvsngpEVQTVHEEEEQDEQGEGSEDeweqvgprN--- 598
           *9999999999966599********************4455588888888888777633333334434444444444355555552... PP
   S: 134  kkkknk...........slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekc 211
                k           ++i+d+F+g+++ +++ ++  ++s + +pf++l+l++++++ +   ++qd+Les +++e+++g    y++k 
   Q: 599  -----KssvtrqadfvqTPITDIFGGHIR-SVVYQQSSKESATLQPFFTLQLDIQSDKIR---TVQDALESLVARESVQG----YTTKT 674
           .....444445555666***********9.688999999*******************99...****************8....99999 PP
   S: 212  kkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...kkkYeLia.vvvHsG.slssGHY 295
           k+++e +++++l++lP+vL+lhLkRf ++++++++ k+ k++e+p  L++s+ + sp  k+k    +++Y+L+a vv+H+G s+ +GHY
   Q: 675  KQEVEISRRVTLEELPPVLVLHLKRFVYEKTGGCQ-KLIKNIEYPVDLEISKELLSPGVKSKIfkgQRTYRLFAeVVYHHGnSATGGHY 762
           ****************************9998886.****************99998877766888********9999*********** PP
   S: 296  vayvknekgk.WllfdDskVtevkeeevleetg.staYvlfYkr 337
           +++v +   + Wl++dD+ V+++++ +v++ ++ +taY+l+Y+r
   Q: 763  TTDVFQIGLNgWLRIDDQAVKVINQYQVVKPSAeRTAYLLYYRR 806
           ******87777*****************998778********98 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

LSSSIAQYIF GEFSPDEFNQ FFVTPRCSVE LPPYNETVSC GIKSTGIYEN DFILFFSEML 60
HRFQSGEEYQ RIEFGVNEVI ETESSVLNNT DYSISSTLNP QAPEFILSCA PAQKTPDDSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCAGTAGTA GTATTGCTCA GGGAAGTGAA GTGATGTGTA GGTATCTGTG CTGTTCTAGA 60
AGGTAAAACT GGTTGTGTGT GGGGCTTATA TGAGCTGACA CAACTCTAGT GTCTCACTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS50235--USP_3

Pfam

PF07145--PAM2
PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071347--P:cellular response to interleukin-1
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	31.38	6.00e-46	178.00
IUUC-Aml-001584	Ailuropoda melanoleuca	75.74	0.00e+00	1159.00
IUUC-Atr-002927	Amborella trichopoda	34.53	3.00e-58	219.00
IUUC-Apl-003988	Anas platyrhynchos	94.05	0.00e+00	1430.00
IUUC-Aca-004461	Anolis carolinensis	96.72	9.00e-173	598.00
IUUC-Aly-006038	Arabidopsis lyrata	34.18	2.00e-54	206.00
IUUC-Ath-007328	Arabidopsis thaliana	33.93	6.00e-53	201.00
IUUC-Ago-007717	Ashbya gossypii	27.87	1.00e-42	167.00
IUUC-Acl-008188	Aspergillus clavatus	35.59	5.00e-62	232.00
IUUC-Afl-008456	Aspergillus flavus	36.48	8.00e-48	184.00
IUUC-Afu-009067	Aspergillus fumigatus	36.57	5.00e-64	239.00
IUUC-Ani-009483	Aspergillus nidulans	34.96	6.00e-61	228.00
IUUC-Ang-009639	Aspergillus niger	35.29	4.00e-61	229.00
IUUC-Aor-010040	Aspergillus oryzae	34.61	2.00e-60	226.00
IUUC-Ate-010310	Aspergillus terreus	34.43	3.00e-60	226.00
IUUC-Ame-011012	Astyanax mexicanus	73.54	9.00e-174	603.00
IUUC-Bgr-012311	Blumeria graminis	35.51	1.00e-46	181.00
IUUC-Bta-013299	Bos taurus	75.09	0.00e+00	1111.00
IUUC-Bci-013783	Botrytis cinerea	36.32	8.00e-60	225.00
IUUC-Bdi-015039	Brachypodium distachyon	32.66	5.00e-50	192.00
IUUC-Bol-015806	Brassica oleracea	36.48	3.00e-63	236.00
IUUC-Bra-017076	Brassica rapa	35.85	9.00e-64	237.00
IUUC-Cja-018715	Callithrix jacchus	74.48	0.00e+00	1158.00
IUUC-Cfa-020194	Canis familiaris	77.37	0.00e+00	1178.00
IUUC-Cpo-022272	Cavia porcellus	65.26	0.00e+00	930.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	34.88	3.00e-33	135.00
IUUC-Csa-023310	Chlorocebus sabaeus	76.79	0.00e+00	1171.00
IUUC-Cho-024966	Choloepus hoffmanni	72.32	0.00e+00	795.00
IUUC-Cin-025616	Ciona intestinalis	48.80	5.00e-108	384.00
IUUC-Csv-026043	Ciona savignyi	46.43	1.00e-98	352.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	34.03	1.00e-45	177.00
IUUC-Cne-026962	Cryptococcus neoformans	34.92	6.00e-48	186.00
IUUC-Cme-027113	Cyanidioschyzon merolae	30.84	8.00e-36	144.00
IUUC-Dre-028072	Danio rerio	79.87	0.00e+00	741.00
IUUC-Dno-029489	Dasypus novemcinctus	76.78	0.00e+00	1210.00
IUUC-Dor-031068	Dipodomys ordii	69.35	4.00e-134	471.00
IUUC-Dse-031553	Dothistroma septosporum	36.80	2.00e-58	220.00
IUUC-Dme-031759	Drosophila melanogaster	42.03	2.00e-84	307.00
IUUC-Ete-032549	Echinops telfairi	69.90	0.00e+00	787.00
IUUC-Eca-033380	Equus caballus	76.05	0.00e+00	1183.00
IUUC-Eeu-034818	Erinaceus europaeus	74.94	0.00e+00	1125.00
IUUC-Fca-035535	Felis catus	75.33	0.00e+00	1040.00
IUUC-Fal-036627	Ficedula albicollis	86.94	0.00e+00	1321.00
IUUC-Fox-037904	Fusarium oxysporum	36.73	5.00e-54	205.00
IUUC-Fso-038170	Fusarium solani	33.41	4.00e-53	202.00
IUUC-Gmo-039499	Gadus morhua	69.87	0.00e+00	686.00
IUUC-Ggr-040042	Gaeumannomyces graminis	34.84	3.00e-60	226.00
IUUC-Gga-040571	Gallus gallus	96.27	0.00e+00	1437.00
IUUC-Gac-041345	Gasterosteus aculeatus	78.71	0.00e+00	692.00
IUUC-Gma-044407	Glycine max	35.46	8.00e-59	221.00
IUUC-Ggo-044652	Gorilla gorilla	75.56	0.00e+00	1180.00
IUUC-Hsa-045864	Homo sapiens	75.43	0.00e+00	1178.00
IUUC-Hvu-047071	Hordeum vulgare	32.92	3.00e-53	202.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	82.42	0.00e+00	926.00
IUUC-Kpa-049132	Komagataella pastoris	30.87	2.00e-45	176.00
IUUC-Lch-050040	Latimeria chalumnae	76.36	0.00e+00	1043.00
IUUC-Lpe-050772	Leersia perrieri	29.09	4.00e-16	79.00
IUUC-Loc-052449	Lepisosteus oculatus	77.28	0.00e+00	753.00
IUUC-Lma-053248	Leptosphaeria maculans	35.03	1.00e-57	218.00
IUUC-Laf-054121	Loxodonta africana	75.55	0.00e+00	1177.00
IUUC-Mcc-055514	Macaca mulatta	76.32	0.00e+00	1169.00
IUUC-Meu-056873	Macropus eugenii	74.54	0.00e+00	868.00
IUUC-Mor-057243	Magnaporthe oryzae	33.25	2.00e-57	217.00
IUUC-Mpo-057439	Magnaporthe poae	35.11	2.00e-60	227.00
IUUC-Mtr-058457	Medicago truncatula	33.67	3.00e-56	212.00
IUUC-Mla-058929	Melampsora laricipopulina	30.68	5.00e-55	208.00
IUUC-Mvi-060442	Microbotryum violaceum	32.32	2.00e-53	204.00
IUUC-Mmr-061062	Microcebus murinus	74.36	0.00e+00	1174.00
IUUC-Mdo-062798	Monodelphis domestica	81.87	0.00e+00	1250.00
IUUC-Mmu-064050	Mus musculus	71.57	0.00e+00	1105.00
IUUC-Mac-065202	Musa acuminata	33.81	4.00e-53	201.00
IUUC-Mpu-066554	Mustela putorius furo	74.78	0.00e+00	1127.00
IUUC-Mlu-068003	Myotis lucifugus	76.33	0.00e+00	1170.00
IUUC-Nfi-068612	Neosartorya fischeri	35.53	2.00e-62	233.00
IUUC-Ncr-068878	Neurospora crassa	34.10	1.00e-49	191.00
IUUC-Nle-069661	Nomascus leucogenys	75.31	0.00e+00	1169.00
IUUC-Opr-070944	Ochotona princeps	74.15	6.00e-164	570.00
IUUC-Ont-071266	Oreochromis niloticus	60.81	0.00e+00	855.00
IUUC-Oan-073442	Ornithorhynchus anatinus	85.20	0.00e+00	1219.00
IUUC-Ocu-073788	Oryctolagus cuniculus	71.48	0.00e+00	1014.00
IUUC-Oba-075085	Oryza barthii	33.93	3.00e-36	144.00
IUUC-Obr-076663	Oryza brachyantha	30.71	2.00e-46	180.00
IUUC-Ogl-076937	Oryza glaberrima	30.04	5.00e-49	188.00
IUUC-Ogu-078909	Oryza glumaepatula	30.37	4.00e-47	182.00
IUUC-Oin-079617	Oryza indica	31.23	7.00e-49	188.00
IUUC-Olo-081043	Oryza longistaminata	26.15	2.00e-23	103.00
IUUC-Ome-081646	Oryza meridionalis	25.13	3.00e-22	100.00
IUUC-Oni-082914	Oryza nivara	30.37	3.00e-47	182.00
IUUC-Oru-084878	Oryza rufipogon	30.37	2.00e-47	183.00
IUUC-Osa-085822	Oryza sativa	30.82	3.00e-51	195.00
IUUC-Ola-086931	Oryzias latipes	58.55	0.00e+00	813.00
IUUC-Oga-088443	Otolemur garnettii	74.69	0.00e+00	1167.00
IUUC-Oar-089325	Ovis aries	73.09	0.00e+00	1036.00
IUUC-Ptr-091584	Pan troglodytes	72.96	0.00e+00	1102.00
IUUC-Pan-092551	Papio anubis	74.81	0.00e+00	1129.00
IUUC-Psi-093366	Pelodiscus sinensis	89.83	0.00e+00	869.00
IUUC-Pno-095136	Phaeosphaeria nodorum	34.76	7.00e-49	188.00
IUUC-Ppa-095574	Physcomitrella patens	36.88	8.00e-61	227.00
IUUC-Pfo-097462	Poecilia formosa	79.66	0.00e+00	721.00
IUUC-Pab-098547	Pongo abelii	75.31	0.00e+00	1167.00
IUUC-Pop-099529	Populus trichocarpa	37.76	2.00e-63	236.00
IUUC-Pca-101066	Procavia capensis	68.23	0.00e+00	1027.00
IUUC-Ppe-102110	Prunus persica	35.87	1.00e-60	226.00
IUUC-Pva-103015	Pteropus vampyrus	78.75	0.00e+00	1055.00
IUUC-Ptt-103998	Puccinia triticina	32.43	7.00e-53	201.00
IUUC-Pte-104417	Pyrenophora teres	33.33	2.00e-55	210.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	34.62	9.00e-54	204.00
IUUC-Rno-105533	Rattus norvegicus	73.58	0.00e+00	1121.00
IUUC-Sce-106160	Saccharomyces cerevisiae	27.06	3.00e-39	156.00
IUUC-Sha-106590	Sarcophilus harrisii	81.58	0.00e+00	1227.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	34.95	2.00e-56	212.00
IUUC-Spo-108353	Schizosaccharomyces pombe	36.14	2.00e-61	229.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	36.13	2.00e-59	223.00
IUUC-Smo-108842	Selaginella moellendorffii	35.59	2.00e-37	148.00
IUUC-Sit-110781	Setaria italica	33.18	5.00e-55	208.00
IUUC-Sly-111797	Solanum lycopersicum	34.61	2.00e-55	209.00
IUUC-Stu-112188	Solanum tuberosum	34.52	1.00e-56	213.00
IUUC-Sbi-114862	Sorghum bicolor	33.43	5.00e-45	175.00
IUUC-Sre-115162	Sporisorium reilianum	34.16	9.00e-62	231.00
IUUC-Ssc-115505	Sus scrofa	89.07	8.00e-157	545.00
IUUC-Tgu-116535	Taeniopygia guttata	88.17	0.00e+00	1348.00
IUUC-Tru-117542	Takifugu rubripes	59.55	0.00e+00	863.00
IUUC-Tni-120200	Tetraodon nigroviridis	58.86	0.00e+00	858.00
IUUC-Tca-121548	Theobroma cacao	33.83	8.00e-47	181.00
IUUC-Tre-122124	Trichoderma reesei	32.41	7.00e-60	224.00
IUUC-Tvi-122457	Trichoderma virens	34.22	8.00e-53	201.00
IUUC-Tae-125646	Triticum aestivum	34.60	3.00e-56	213.00
IUUC-Tme-127180	Tuber melanosporum	38.81	3.00e-69	255.00
IUUC-Tbe-127530	Tupaia belangeri	64.65	0.00e+00	910.00
IUUC-Ttr-128549	Tursiops truncatus	69.69	0.00e+00	1044.00
IUUC-Uma-129381	Ustilago maydis	33.33	3.00e-60	226.00
IUUC-Vda-129889	Verticillium dahliae	33.16	2.00e-52	201.00
IUUC-Vpa-130100	Vicugna pacos	70.78	0.00e+00	1044.00
IUUC-Vvi-131366	Vitis vinifera	34.55	6.00e-63	234.00
IUUC-Xtr-132048	Xenopus tropicalis	67.56	0.00e+00	1007.00
IUUC-Xma-133593	Xiphophorus maculatus	78.80	0.00e+00	715.00
IUUC-Yli-134338	Yarrowia lipolytica	29.75	9.00e-35	141.00
IUUC-Zma-135586	Zea mays	29.34	2.00e-49	189.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence