iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035921

Ensembl Protein ID

ENSFCAP00000024623.1

UniProt Accession

M3XDB7; M3XDB7_FELCA

Genbank Protein ID

ENSFCAP00000024623

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02138005

Gene Name

TBK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000028816.1	ENSFCAT00000030800.1	ENSFCAP00000024623.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	90.71	0.00e+00	1396.00	IUUC-Mmu-064107

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Felis catus

Protein Sequence
(Fasta)

MQSTSNHLWL LSDILGQGAT ANVFRGRHKE TKIIQSIILF PGIYFKKPCL FSVTKKDHEI 60
LRKKLNHKNI VKLFAIEEET TTRHKVLIME FCPCGSLYTV LEEPSNAYGL PESEFLIVLR 120

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Nucleotide Sequence
(Fasta)

ATGCAGAGCA CCTCTAATCA TCTGTGGCTT TTGTCTGATA TTTTAGGCCA AGGAGCTACT 60
GCAAATGTCT TTCGTGGAAG GCATAAGGTT GGTTCAAAGA AAACCGTGAA CACTTTTTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom

PROSITE

PS50011--PROTEIN_KINASE_DOM

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003676--F:nucleic acid binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0002218--P:activation of innate immune response
GO:0050830--P:defense response to Gram-positive bacterium
GO:0044565--P:dendritic cell proliferation
GO:0045087--P:innate immune response
GO:0010629--P:negative regulation of gene expression
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032727--P:positive regulation of interferon-alpha production
GO:0045359--P:positive regulation of interferon-beta biosynthetic process
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:1904417--P:positive regulation of xenophagy

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001638	Ailuropoda melanoleuca	95.49	0.00e+00	1442.00
IUUC-Apl-004028	Anas platyrhynchos	83.88	0.00e+00	1300.00
IUUC-Aca-004998	Anolis carolinensis	79.37	0.00e+00	1230.00
IUUC-Ame-011617	Astyanax mexicanus	67.58	0.00e+00	1006.00
IUUC-Bta-012799	Bos taurus	94.26	0.00e+00	1433.00
IUUC-Cja-019357	Callithrix jacchus	94.00	0.00e+00	1425.00
IUUC-Cfa-020309	Canis familiaris	94.67	0.00e+00	1434.00
IUUC-Cpo-022062	Cavia porcellus	92.90	0.00e+00	1407.00
IUUC-Csa-023517	Chlorocebus sabaeus	93.99	0.00e+00	1430.00
IUUC-Cho-025037	Choloepus hoffmanni	93.94	0.00e+00	971.00
IUUC-Cin-025580	Ciona intestinalis	38.83	6.00e-139	488.00
IUUC-Csv-025818	Ciona savignyi	38.51	4.00e-133	468.00
IUUC-Dre-027527	Danio rerio	67.67	0.00e+00	1019.00
IUUC-Dno-029475	Dasypus novemcinctus	81.64	0.00e+00	1076.00
IUUC-Dme-031698	Drosophila melanogaster	37.36	1.00e-119	423.00
IUUC-Ete-033090	Echinops telfairi	79.51	0.00e+00	1169.00
IUUC-Eca-033996	Equus caballus	92.21	0.00e+00	1412.00
IUUC-Eeu-035082	Erinaceus europaeus	84.00	0.00e+00	805.00
IUUC-Fal-037406	Ficedula albicollis	84.02	0.00e+00	1305.00
IUUC-Gmo-038721	Gadus morhua	67.55	0.00e+00	991.00
IUUC-Gga-041234	Gallus gallus	83.74	0.00e+00	1302.00
IUUC-Gac-042315	Gasterosteus aculeatus	68.27	0.00e+00	1009.00
IUUC-Ggo-044885	Gorilla gorilla	87.43	0.00e+00	1312.00
IUUC-Hsa-046847	Homo sapiens	93.85	0.00e+00	1427.00
IUUC-Itr-047906	Ictidomys tridecemlineatus	93.09	0.00e+00	1415.00
IUUC-Lch-049731	Latimeria chalumnae	52.02	0.00e+00	726.00
IUUC-Loc-051879	Lepisosteus oculatus	69.77	0.00e+00	1050.00
IUUC-Laf-054232	Loxodonta africana	92.09	0.00e+00	1404.00
IUUC-Mcc-055447	Macaca mulatta	94.13	0.00e+00	1432.00
IUUC-Meu-056138	Macropus eugenii	89.82	0.00e+00	629.00
IUUC-Mga-059460	Meleagris gallopavo	82.56	0.00e+00	1274.00
IUUC-Mmr-061445	Microcebus murinus	94.13	0.00e+00	1426.00
IUUC-Mmu-064107	Mus musculus	90.71	0.00e+00	1372.00
IUUC-Mpu-066834	Mustela putorius furo	95.22	0.00e+00	1443.00
IUUC-Mlu-068006	Myotis lucifugus	90.18	0.00e+00	1347.00
IUUC-Nle-069280	Nomascus leucogenys	93.72	0.00e+00	1427.00
IUUC-Opr-070728	Ochotona princeps	89.28	0.00e+00	1194.00
IUUC-Ont-071621	Oreochromis niloticus	69.30	0.00e+00	1025.00
IUUC-Oan-073162	Ornithorhynchus anatinus	88.95	0.00e+00	1311.00
IUUC-Ocu-074787	Oryctolagus cuniculus	94.27	0.00e+00	1428.00
IUUC-Ola-086737	Oryzias latipes	31.76	2.00e-25	110.00
IUUC-Oga-088764	Otolemur garnettii	91.94	0.00e+00	1405.00
IUUC-Oar-090333	Ovis aries	94.00	0.00e+00	1427.00
IUUC-Ptr-090568	Pan troglodytes	93.85	0.00e+00	1425.00
IUUC-Pan-091979	Papio anubis	93.87	0.00e+00	1423.00
IUUC-Psi-093336	Pelodiscus sinensis	83.47	0.00e+00	1281.00
IUUC-Pma-094200	Petromyzon marinus	42.23	4.00e-160	558.00
IUUC-Pfo-096354	Poecilia formosa	68.23	0.00e+00	1019.00
IUUC-Pab-098499	Pongo abelii	93.99	0.00e+00	1429.00
IUUC-Pva-102454	Pteropus vampyrus	92.62	0.00e+00	1389.00
IUUC-Rno-105595	Rattus norvegicus	90.98	0.00e+00	1366.00
IUUC-Sha-106864	Sarcophilus harrisii	89.93	0.00e+00	1385.00
IUUC-Sar-113728	Sorex araneus	85.94	0.00e+00	1212.00
IUUC-Tgu-117200	Taeniopygia guttata	82.72	0.00e+00	1284.00
IUUC-Tsy-119017	Tarsius syrichta	92.05	0.00e+00	1031.00
IUUC-Tni-120724	Tetraodon nigroviridis	67.49	0.00e+00	1010.00
IUUC-Tbe-127887	Tupaia belangeri	83.02	0.00e+00	982.00
IUUC-Ttr-129111	Tursiops truncatus	86.61	0.00e+00	1292.00
IUUC-Vpa-130724	Vicugna pacos	94.95	0.00e+00	1439.00
IUUC-Xtr-132091	Xenopus tropicalis	71.39	0.00e+00	1103.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence