iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-090753

Ensembl Protein ID

ENSPTRP00000007266.3

UniProt Accession

H2Q4N5; H2Q4N5_PANTR

Genbank Protein ID

JAA03475.1; JAA15667.1; JAA24156.1; JAA34385.1

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Genbank Nucleotide ID

AACZ03081072; GABF01006478; GABD01008944; GABE01010354

Gene Name

DCUN1D5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000004223.3	ENSPTRT00000007874.3	ENSPTRP00000007266.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	1.90e-83	279.1	47	232

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkd 90
           s+kk+ ++f++Y++p+e ++g eg+ekfced+gv+pe+i++Lvlawklea+++++f++ee+l+g+t+l+cd++eklq+k+++l+s+l+d
   Q: 47   SSKKCLAWFYEYAGPDE-VVGPEGMEKFCEDIGVEPENIIMLVLAWKLEAESMGFFTKEEWLKGMTSLQCDCTEKLQNKFDFLRSQLND 134
           78*************95.*********************************************************************** PP
   S: 91   eqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWPv 179
           +++fk+iYr+af+fa+dk+q+sld+dta+++++Lll +r+++l+++++++Le++k+++++kD+W+++Lefs+++++dlsnYde+gaWPv
   Q: 135  ISSFKNIYRYAFDFARDKDQRSLDIDTAKSMLALLL-GRTWPLFSVFYQYLEQSKYRVMNKDQWYNVLEFSRTVHADLSNYDEDGAWPV 222
           ************************************.999************************************************* PP
   S: 180  liDefveylk 189
           l+Defve++k
   Q: 223  LLDEFVEWQK 232
           ********86 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MPVKKKRKSP GVAAAVAEDG GLKKCKISSY CRSQPPARLI SGEEHFSSKK CLAWFYEYAG 60
PDEVVGPEGM EKFCEDIGVE PENIIMLVLA WKLEAESMGF FTKEEWLKGM TSLQCDCTEK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCTCTTGCT TGCTGTGACT GGTGGAGCTG CCGCGCTGTG CGCGTTATCT CCTCCCGGTG 60
AGAACGAACC GCAGTGTCCA CCGGCGAGGA GCCAGCCCTG TCCCGGTCAG AGAAAGACGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001567	Ailuropoda melanoleuca	99.58	3.00e-141	493.00
IUUC-Apl-003338	Anas platyrhynchos	87.34	2.00e-123	434.00
IUUC-Aca-004660	Anolis carolinensis	90.30	1.00e-127	448.00
IUUC-Afu-009005	Aspergillus fumigatus	31.07	5.00e-17	80.50
IUUC-Bta-013463	Bos taurus	98.31	1.00e-137	481.00
IUUC-Cja-019665	Callithrix jacchus	100.00	2.00e-141	493.00
IUUC-Cfa-020873	Canis familiaris	98.73	3.00e-140	490.00
IUUC-Csa-023661	Chlorocebus sabaeus	100.00	2.00e-141	493.00
IUUC-Cin-025635	Ciona intestinalis	56.71	2.00e-52	197.00
IUUC-Csv-025976	Ciona savignyi	56.48	8.00e-63	233.00
IUUC-Cme-027199	Cyanidioschyzon merolae	23.31	7.00e-08	50.80
IUUC-Dre-028080	Danio rerio	78.39	1.00e-111	395.00
IUUC-Dno-029984	Dasypus novemcinctus	98.33	2.00e-138	485.00
IUUC-Dor-030556	Dipodomys ordii	97.05	8.00e-137	478.00
IUUC-Eca-034108	Equus caballus	100.00	2.00e-141	493.00
IUUC-Fca-035374	Felis catus	90.68	5.00e-125	439.00
IUUC-Fal-037284	Ficedula albicollis	94.37	9.00e-120	422.00
IUUC-Gga-040330	Gallus gallus	92.41	4.00e-130	456.00
IUUC-Gac-042443	Gasterosteus aculeatus	75.32	1.00e-101	361.00
IUUC-Ggo-044892	Gorilla gorilla	100.00	2.00e-141	493.00
IUUC-Hsa-046320	Homo sapiens	100.00	2.00e-141	493.00
IUUC-Itr-048437	Ictidomys tridecemlineatus	100.00	1.00e-73	267.00
IUUC-Lch-049750	Latimeria chalumnae	87.76	2.00e-123	434.00
IUUC-Loc-052941	Lepisosteus oculatus	84.81	8.00e-120	422.00
IUUC-Laf-054402	Loxodonta africana	99.16	2.00e-140	490.00
IUUC-Mcc-055269	Macaca mulatta	100.00	2.00e-141	493.00
IUUC-Meu-056847	Macropus eugenii	84.47	9.00e-107	379.00
IUUC-Mga-059420	Meleagris gallopavo	94.34	3.00e-118	417.00
IUUC-Mmr-061732	Microcebus murinus	99.58	6.00e-141	492.00
IUUC-Mdo-062269	Monodelphis domestica	97.47	9.00e-129	452.00
IUUC-Mmu-063396	Mus musculus	97.18	2.00e-123	434.00
IUUC-Mpu-066206	Mustela putorius furo	99.40	4.00e-98	349.00
IUUC-Mlu-067871	Myotis lucifugus	99.16	8.00e-140	488.00
IUUC-Nfi-068610	Neosartorya fischeri	31.64	7.00e-18	83.20
IUUC-Nle-069808	Nomascus leucogenys	100.00	2.00e-141	493.00
IUUC-Opr-070404	Ochotona princeps	98.23	1.00e-62	232.00
IUUC-Ont-072416	Oreochromis niloticus	71.79	3.00e-96	344.00
IUUC-Oan-072930	Ornithorhynchus anatinus	88.03	2.00e-120	424.00
IUUC-Ocu-073767	Oryctolagus cuniculus	99.16	2.00e-140	490.00
IUUC-Ola-086378	Oryzias latipes	69.75	7.00e-96	342.00
IUUC-Oga-088583	Otolemur garnettii	100.00	2.00e-141	493.00
IUUC-Oar-089612	Ovis aries	98.09	5.00e-123	432.00
IUUC-Pan-091951	Papio anubis	100.00	2.00e-141	493.00
IUUC-Psi-093385	Pelodiscus sinensis	94.09	3.00e-124	437.00
IUUC-Pma-094582	Petromyzon marinus	72.15	1.00e-99	355.00
IUUC-Pfo-096222	Poecilia formosa	70.66	2.00e-96	345.00
IUUC-Pab-097692	Pongo abelii	100.00	2.00e-141	493.00
IUUC-Pva-102620	Pteropus vampyrus	99.09	1.00e-128	451.00
IUUC-Rno-105023	Rattus norvegicus	97.65	3.00e-124	437.00
IUUC-Sha-107177	Sarcophilus harrisii	97.47	9.00e-129	452.00
IUUC-Sar-113656	Sorex araneus	87.02	5.00e-103	366.00
IUUC-Ssc-116272	Sus scrofa	99.16	5.00e-140	489.00
IUUC-Tgu-116631	Taeniopygia guttata	92.24	2.00e-118	417.00
IUUC-Tsy-119350	Tarsius syrichta	99.16	2.00e-140	490.00
IUUC-Tbe-127515	Tupaia belangeri	92.80	1.00e-127	448.00
IUUC-Ttr-128784	Tursiops truncatus	75.53	1.00e-95	342.00
IUUC-Vpa-130543	Vicugna pacos	99.58	3.00e-141	493.00
IUUC-Xtr-132448	Xenopus tropicalis	87.71	4.00e-124	436.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence