iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggr-039917

Ensembl Protein ID

GGTG_02880T0

UniProt Accession

J3NNM3; J3NNM3_GAGT3

Genbank Protein ID

EJT77775.1

Protein Name

Cullin-1

Genbank Nucleotide ID

ADBI01000268

Gene Name

GGTG_02880

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GGTG_02880	GGTG_02880T0	GGTG_02880T0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	3.80e-182	606.7	29	665

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 3    reavkkilr..qesv.kkeyeelytavynlclsk....................vgaklYkklkevleefikqvkkkveesedeqlLktynreWekf 76
           ++++k+i++  q+ +  ++y+ +ytav+n+c+s+                    +g+ lYkkl  +l+ +++++ +k +++++e+lL +y+reW ++
   Q: 29   QNGIKRIMNnlQDGMtMETYMGIYTAVHNFCTSQkvvgfpqqaqpagahrgahlLGEDLYKKLIGYLTLHLEDLLEKSKAHTGEALLSFYIREWDRY 125
           677777765336888899******************************************************************************* PP
   S: 77   reqlkvlrkifayldrtyvkk.....skkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslveLslnk.......l 161
           ++++k+++++f+yl+r++vk+     +k++ +v++L l  w++ ++e+++ +++e++l+l+e++R+ge+++   ++++  s+v+L+l++       l
   Q: 126  TTAAKYVHHLFRYLNRHWVKReidegKKHIFDVYTLHLVQWKNVLFEKVHGKVMEAVLNLVEKQRNGETIEYGQIKQILDSMVSLGLDEndaskttL 222
           *********************999998999**********************************************************99******* PP
   S: 162  aiykesFEakfleatqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesllaelvallrdkktedlsrm 258
             y+  FE++f  at+ +y++es +f++en+v eY+kk+e rl+eeeer++ yl++     L ++++++lia+h   l +e++ ll++++++d++rm
   Q: 223  DCYRFHFEKPFIAATESYYRNESRAFVAENSVVEYMKKAEMRLEEEEERVRMYLHPDIAVALKRCCNQALIADHSGILRDEFQVLLDNDREDDMARM 319
           ************************************************************************************************* PP
   S: 259  ykLlsrvlngleellkeleshikeqgkaalt...aeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlka..akspE 350
           y+Ll+r+++gl++l+ ++e+h++++g+aa++   + +++ +pk yV  lle++ ++q lv++aFn++++F+ +ld+a+++fvn+n v k    kspE
   Q: 320  YNLLARISDGLDPLRAKFEAHVRKAGLAAVAkvsSDAEKLEPKVYVDALLEVHTQYQGLVKRAFNDEPEFTRSLDNACREFVNRNDVCKSgsNKSPE 416
           ******************************98755555569************************************************998999** PP
   S: 351  llAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfqdlkvSedl 447
           llA+y D lLrks   ++e+elea+l+++++vfkyi++kdvF+k+Y ++La+RL++ +s s++aE s+i+kLke+cg+e+t+kL+rMfqd+++S+dl
   Q: 417  LLAKYTDVLLRKSGSAVEEAELEATLTQIMTVFKYIEDKDVFQKFYSRMLARRLVHSNSSSDDAETSMISKLKEACGFEYTNKLQRMFQDMQTSKDL 513
           ************************************************************************************************* PP
   S: 448  nrqFkeekenteesesvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkkg...kyelqVstfQma 541
           n+ F+++ ++ +e + ++ +  +L +g+Wp ++   +++ Pa +++ +++f++fY++kh+gRkL+W+++l+++elka + k    +y++qVs +Qma
   Q: 514  NHGFRDHAQK-SELKLLDSQYAILGTGFWPLQPPNTSFNPPAVIHQDCDRFTRFYKNKHEGRKLTWLWQLCKGELKAGYCKSsktPYTFQVSMYQMA 609
           *****66665.58888999*************99999****************************************88555556************ PP
   S: 542  vLLafnnsekvsveelkkatelpeeeLrrtlqsLvsskkqvlkkepeskeieeedlfsvN 601
           +LL+fn++++ +++e++ at+l+ e +   +++Lv+ k  vl +++e+     ++++ +N
   Q: 610  ILLMFNEEDTHTYDEIASATNLNSEAMDPSIGVLVKAK--VLLADNEKPG--PGTTYRLN 665
           ************************************98..8888877532..45555555 PP

Organism

Gaeumannomyces graminis

Protein Sequence
(Fasta)

MAPPITGRGL SIPSGTKSED IDVTWNYLQN GIKRIMNNLQ DGMTMETYMG IYTAVHNFCT 60
SQKVVGFPQQ AQPAGAHRGA HLLGEDLYKK LIGYLTLHLE DLLEKSKAHT GEALLSFYIR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACGTTGGCA GCCTAATGAT CAGCTTCGAT TGCCTGGCCT AACGTCGCGA TATTGTGCTG 60
GAATCCCGTC GCAGCCTCAC CCGTCATCTG TGATTTCTGT CTCGGGAAGT CCTCCAGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0005829--C:cytosol
GO:0043224--C:nuclear SCF ubiquitin ligase complex
GO:1903467--P:negative regulation of mitotic DNA replication initiation
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002277	Ailuropoda melanoleuca	47.61	0.00e+00	686.00
IUUC-Apl-003503	Anas platyrhynchos	47.70	2.00e-156	544.00
IUUC-Aca-005030	Anolis carolinensis	41.03	5.00e-145	506.00
IUUC-Ago-007977	Ashbya gossypii	33.62	1.00e-128	452.00
IUUC-Acl-008190	Aspergillus clavatus	66.06	0.00e+00	1001.00
IUUC-Afl-008542	Aspergillus flavus	67.64	0.00e+00	806.00
IUUC-Afu-009007	Aspergillus fumigatus	66.09	0.00e+00	947.00
IUUC-Ani-009290	Aspergillus nidulans	64.92	0.00e+00	1020.00
IUUC-Ang-009600	Aspergillus niger	65.50	0.00e+00	967.00
IUUC-Aor-009978	Aspergillus oryzae	64.11	0.00e+00	885.00
IUUC-Ate-010584	Aspergillus terreus	66.19	0.00e+00	1015.00
IUUC-Ame-011861	Astyanax mexicanus	47.11	0.00e+00	670.00
IUUC-Bgr-012209	Blumeria graminis	70.30	0.00e+00	1056.00
IUUC-Bta-012878	Bos taurus	47.61	0.00e+00	682.00
IUUC-Bci-013941	Botrytis cinerea	71.52	0.00e+00	1151.00
IUUC-Cel-018294	Caenorhabditis elegans	38.54	6.00e-154	536.00
IUUC-Cja-018965	Callithrix jacchus	46.26	0.00e+00	656.00
IUUC-Cfa-020671	Canis familiaris	47.61	0.00e+00	682.00
IUUC-Cpo-021762	Cavia porcellus	47.74	0.00e+00	684.00
IUUC-Cre-022776	Chlamydomonas reinhardtii	30.59	8.00e-97	346.00
IUUC-Csa-023873	Chlorocebus sabaeus	47.74	0.00e+00	684.00
IUUC-Cin-025547	Ciona intestinalis	45.50	0.00e+00	626.00
IUUC-Csv-026083	Ciona savignyi	45.66	0.00e+00	655.00
IUUC-Cgl-026452	Colletotrichum gloeosporioides	74.61	0.00e+00	1193.00
IUUC-Cne-026919	Cryptococcus neoformans	47.08	0.00e+00	687.00
IUUC-Dre-027875	Danio rerio	47.16	0.00e+00	669.00
IUUC-Dno-028931	Dasypus novemcinctus	47.87	0.00e+00	682.00
IUUC-Dor-030846	Dipodomys ordii	51.54	2.00e-141	494.00
IUUC-Dse-031472	Dothistroma septosporum	63.10	0.00e+00	938.00
IUUC-Dme-031793	Drosophila melanogaster	44.44	2.00e-178	617.00
IUUC-Ete-033112	Echinops telfairi	45.19	3.00e-75	275.00
IUUC-Eca-034309	Equus caballus	47.61	0.00e+00	682.00
IUUC-Fca-036330	Felis catus	47.11	0.00e+00	664.00
IUUC-Fal-036899	Ficedula albicollis	47.62	3.00e-162	563.00
IUUC-Fox-037705	Fusarium oxysporum	70.52	0.00e+00	1097.00
IUUC-Fso-038367	Fusarium solani	72.08	0.00e+00	1132.00
IUUC-Gmo-038708	Gadus morhua	46.92	0.00e+00	666.00
IUUC-Gga-041038	Gallus gallus	47.74	0.00e+00	684.00
IUUC-Gac-041820	Gasterosteus aculeatus	47.00	0.00e+00	687.00
IUUC-Ggo-045154	Gorilla gorilla	41.09	1.00e-131	462.00
IUUC-Hsa-046034	Homo sapiens	47.74	0.00e+00	684.00
IUUC-Itr-048285	Ictidomys tridecemlineatus	47.74	0.00e+00	685.00
IUUC-Kpa-049231	Komagataella pastoris	37.12	6.00e-142	496.00
IUUC-Lch-049673	Latimeria chalumnae	47.74	0.00e+00	682.00
IUUC-Loc-052490	Lepisosteus oculatus	47.75	0.00e+00	674.00
IUUC-Lma-053191	Leptosphaeria maculans	67.46	0.00e+00	1007.00
IUUC-Laf-054582	Loxodonta africana	47.74	0.00e+00	684.00
IUUC-Mcc-055162	Macaca mulatta	47.23	0.00e+00	670.00
IUUC-Meu-055904	Macropus eugenii	46.36	8.00e-75	273.00
IUUC-Mor-057035	Magnaporthe oryzae	85.70	0.00e+00	1330.00
IUUC-Mpo-057555	Magnaporthe poae	98.44	0.00e+00	1553.00
IUUC-Mla-059021	Melampsora laricipopulina	50.66	0.00e+00	726.00
IUUC-Mga-060078	Meleagris gallopavo	47.74	0.00e+00	684.00
IUUC-Mvi-060519	Microbotryum violaceum	50.00	0.00e+00	734.00
IUUC-Mmr-061312	Microcebus murinus	47.74	0.00e+00	684.00
IUUC-Mdo-062867	Monodelphis domestica	47.61	0.00e+00	680.00
IUUC-Mmu-063336	Mus musculus	47.74	0.00e+00	684.00
IUUC-Mpu-066400	Mustela putorius furo	47.46	8.00e-162	562.00
IUUC-Mlu-067800	Myotis lucifugus	47.61	0.00e+00	686.00
IUUC-Nfi-068384	Neosartorya fischeri	64.12	0.00e+00	954.00
IUUC-Ncr-068965	Neurospora crassa	74.65	0.00e+00	1139.00
IUUC-Nle-069729	Nomascus leucogenys	47.74	0.00e+00	684.00
IUUC-Opr-071197	Ochotona princeps	33.53	6.00e-102	363.00
IUUC-Ont-071729	Oreochromis niloticus	46.92	0.00e+00	672.00
IUUC-Oan-073309	Ornithorhynchus anatinus	47.74	0.00e+00	684.00
IUUC-Ocu-074661	Oryctolagus cuniculus	47.69	0.00e+00	674.00
IUUC-Ola-087422	Oryzias latipes	47.36	0.00e+00	674.00
IUUC-Olu-087721	Ostreococcus lucimarinus	28.64	4.00e-78	284.00
IUUC-Oga-088130	Otolemur garnettii	47.74	0.00e+00	684.00
IUUC-Oar-089510	Ovis aries	46.37	0.00e+00	639.00
IUUC-Ptr-090665	Pan troglodytes	47.74	0.00e+00	684.00
IUUC-Pan-092218	Papio anubis	47.74	0.00e+00	684.00
IUUC-Psi-093175	Pelodiscus sinensis	47.74	0.00e+00	684.00
IUUC-Pma-094502	Petromyzon marinus	46.85	0.00e+00	668.00
IUUC-Pno-095067	Phaeosphaeria nodorum	66.23	0.00e+00	1030.00
IUUC-Pfo-096705	Poecilia formosa	47.05	0.00e+00	689.00
IUUC-Pab-097578	Pongo abelii	47.74	0.00e+00	684.00
IUUC-Pca-100242	Procavia capensis	51.72	2.00e-140	491.00
IUUC-Pva-102155	Pteropus vampyrus	41.73	1.00e-160	558.00
IUUC-Pgr-103297	Puccinia graminis	47.64	0.00e+00	704.00
IUUC-Ptt-103706	Puccinia triticina	45.70	4.00e-103	368.00
IUUC-Pte-104257	Pyrenophora teres	66.75	0.00e+00	1034.00
IUUC-Pyt-104795	Pyrenophora triticirepentis	66.62	0.00e+00	1030.00
IUUC-Rno-105939	Rattus norvegicus	47.74	0.00e+00	684.00
IUUC-Sce-106293	Saccharomyces cerevisiae	31.99	1.00e-124	439.00
IUUC-Sha-106949	Sarcophilus harrisii	47.74	0.00e+00	684.00
IUUC-Sja-107737	Schizosaccharomyces japonicus	45.97	0.00e+00	639.00
IUUC-Spo-108280	Schizosaccharomyces pombe	43.99	0.00e+00	630.00
IUUC-Sar-113138	Sorex araneus	37.11	1.00e-125	442.00
IUUC-Sre-114984	Sporisorium reilianum	48.28	0.00e+00	683.00
IUUC-Ssc-115829	Sus scrofa	47.17	0.00e+00	666.00
IUUC-Tgu-116950	Taeniopygia guttata	47.74	0.00e+00	684.00
IUUC-Tru-118558	Takifugu rubripes	47.10	0.00e+00	678.00
IUUC-Tsy-119621	Tarsius syrichta	40.00	7.00e-102	363.00
IUUC-Tni-120460	Tetraodon nigroviridis	46.97	0.00e+00	681.00
IUUC-Tre-122223	Trichoderma reesei	72.46	0.00e+00	1102.00
IUUC-Tvi-122539	Trichoderma virens	71.48	0.00e+00	1094.00
IUUC-Tme-126926	Tuber melanosporum	65.80	0.00e+00	1001.00
IUUC-Tbe-127369	Tupaia belangeri	52.48	2.00e-93	335.00
IUUC-Ttr-129022	Tursiops truncatus	48.06	1.00e-152	531.00
IUUC-Uma-129341	Ustilago maydis	48.10	0.00e+00	657.00
IUUC-Vda-129857	Verticillium dahliae	71.96	0.00e+00	1118.00
IUUC-Vpa-130166	Vicugna pacos	43.49	2.00e-142	497.00
IUUC-Xtr-131818	Xenopus tropicalis	47.61	0.00e+00	682.00
IUUC-Xma-134206	Xiphophorus maculatus	47.05	0.00e+00	675.00
IUUC-Yli-134486	Yarrowia lipolytica	41.12	2.00e-169	587.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence