iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mvi-060476

Ensembl Protein ID

MVLG_03171T0

UniProt Accession

U5H7D7; U5H7D7_USTV1

Genbank Protein ID

KDE06521.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

AEIJ01000288

Gene Name

MVLG_03171

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MVLG_03171	MVLG_03171T0	MVLG_03171T0

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.50e-53	178.5	310	799
UBD/Alpha-Helix/UBA	1.60e-16	58.5	610	647

Active Site

Position(s)	Description	Evidence
319	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
754	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkk.............................av 68
           tG++NlgN+CY+ S +Q+L+++p+++  +l++++ ++ + ++ +p+++l ++l+kl   l++++                                +
   Q: 310  TGMRNLGNSCYLASSMQTLLSLPSIQTRYLTSFHTHVTHCAHLDPTECLECQLAKLADGLLSGRYAvppqddhtdtllgsrdspvssdlppafqvGI 406
           7******************************9****************************74444444455555677888888899999999999** PP
   S: 69   sprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssr 165
           sp+++++ ++k ++efs+++qqDa Ef+a+ll++++++                             + +++  +  F++ ++++++c+ec+ v  +
   Q: 407  SPSMFKALVGKGHSEFSTMRQQDAGEFIAYLLESMRRSS---------------------------RSTGSDDPTSAFGFAMEERLQCPECKGVRYT 476
           ************************************999...........................45666677899****************9955 PP
   S: 166  eepfldlslpvp..gkeetkke...........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksreki 249
           + +   lslpvp   ++++              ++++cL++ +++  +e    y c++c++k+ a+k++ ++++P+vL l   Rf+f++  ++++k+
   Q: 477  TTKEEVLSLPVPivPHKSN--GdhcpedvyepaEFTKCLQELVSPTDVE----YTCPTCDRKVLATKETHFSSFPDVLLLTAARFHFDH--WVPRKV 565
           5555555555552244433..234788888888***************9....********************************9988..****** PP
   S: 250  nkkvefple.Ldlspfcts.............................................................................p 268
           +  +++p e +  ++f  s                                                                             p
   Q: 566  SVPISVPFEpILFDSFQGSglqshetelpdqledtvssepmynpeamgqlavmgfpenrckrallatgnadanvamewlfshmddpnvdlpiehapP 662
           *******999999999999777777777777777777777776666666666666666666666666655555555555555555555555555550 PP
   S: 269  eekqke......................................................................kkkYeLiavvvHsG.slssGH 294
                +                                                                      + kY+L a ++H+G s++sGH
   Q: 663  -----SaaptneelaplvemgftasqaaralhetghdatraidwlfshpeepptddgtssgaaqslqpqnirsttlPAKYQLKAFISHKGpSVHSGH 754
           .....05555555556666666666666666666666667777777777777777777777888888888888899********************* PP
   S: 295  Yvayvknekgk.WllfdDskVtevke.eevleetgstaYvlfYkr 337
           Yva+v+ +++  W+lfdD+kV   ++ ++  e  +  aYv++++r
   Q: 755  YVAHVRGSSDArWVLFDDEKVVRADKgSQSAELLAPLAYVYMFER 799
           ******965556*********9997535555555599***99987 PP

UBD/Alpha-Helix/UBA

   S: 5    dkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           +++ ql  MGF+++++++aL+a+ n ++++A+e+L+++
   Q: 610  EAMGQLAVMGFPENRCKRALLATgNADANVAMEWLFSH 647
           66778889****************************97 PP

Organism

Microbotryum violaceum

Protein Sequence
(Fasta)

MELPDTLLNS LREPRPSQTV YREECTLCFD NHDGPEGIDV CLHCFNGACP ATSTNRHGIL 60
HARKTGHNLH VNIKRIKKPI PAIRRDSFEP PLKKLAIRED VAEHDKYDFV SSVRSYNGEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGTCAGCT CCGACTGCTC AGCGATCACA CAGATAATGG AGCTGCCAGA TACGTTGCTC 60
AACTCGTTAA GGGAACCTAG GCCTTCTCAA ACGGTGTACC GTGAAGGTGA GTTAATCGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	30.99	2.00e-88	318.00
IUUC-Aml-002104	Ailuropoda melanoleuca	34.09	1.00e-126	446.00
IUUC-Atr-002580	Amborella trichopoda	33.37	5.00e-105	374.00
IUUC-Apl-003774	Anas platyrhynchos	34.90	1.00e-125	442.00
IUUC-Aca-005368	Anolis carolinensis	35.32	1.00e-133	468.00
IUUC-Aly-005727	Arabidopsis lyrata	34.31	1.00e-111	395.00
IUUC-Ath-006974	Arabidopsis thaliana	33.96	3.00e-110	390.00
IUUC-Ago-007890	Ashbya gossypii	28.42	3.00e-94	337.00
IUUC-Acl-008057	Aspergillus clavatus	42.56	8.00e-172	595.00
IUUC-Afl-008547	Aspergillus flavus	44.38	2.00e-157	547.00
IUUC-Afu-008805	Aspergillus fumigatus	41.27	3.00e-152	530.00
IUUC-Ani-009441	Aspergillus nidulans	40.43	6.00e-136	476.00
IUUC-Ang-009720	Aspergillus niger	44.86	4.00e-179	619.00
IUUC-Aor-010111	Aspergillus oryzae	43.82	1.00e-179	621.00
IUUC-Ate-010531	Aspergillus terreus	41.24	2.00e-148	517.00
IUUC-Ame-011893	Astyanax mexicanus	36.60	2.00e-106	378.00
IUUC-Bgr-012183	Blumeria graminis	44.57	0.00e+00	630.00
IUUC-Bta-013179	Bos taurus	34.28	1.00e-125	442.00
IUUC-Bci-013858	Botrytis cinerea	45.16	0.00e+00	651.00
IUUC-Bdi-014904	Brachypodium distachyon	32.27	5.00e-95	340.00
IUUC-Bol-015536	Brassica oleracea	34.47	2.00e-110	391.00
IUUC-Bra-017939	Brassica rapa	34.52	6.00e-112	396.00
IUUC-Cel-018625	Caenorhabditis elegans	31.15	1.00e-90	325.00
IUUC-Cja-019063	Callithrix jacchus	34.05	1.00e-124	439.00
IUUC-Cfa-020976	Canis familiaris	35.08	5.00e-129	453.00
IUUC-Cpo-022265	Cavia porcellus	34.73	1.00e-128	452.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	32.35	5.00e-56	210.00
IUUC-Csa-024078	Chlorocebus sabaeus	31.59	3.00e-109	387.00
IUUC-Cho-024702	Choloepus hoffmanni	34.02	6.00e-83	300.00
IUUC-Cin-025411	Ciona intestinalis	33.61	3.00e-104	371.00
IUUC-Csv-026347	Ciona savignyi	32.02	9.00e-100	356.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	43.23	1.00e-168	584.00
IUUC-Cne-026831	Cryptococcus neoformans	47.52	0.00e+00	685.00
IUUC-Cme-027335	Cyanidioschyzon merolae	30.66	6.00e-77	280.00
IUUC-Dre-027982	Danio rerio	34.77	7.00e-111	393.00
IUUC-Dno-029034	Dasypus novemcinctus	34.39	1.00e-126	446.00
IUUC-Dor-030479	Dipodomys ordii	36.78	8.00e-63	233.00
IUUC-Dse-031467	Dothistroma septosporum	42.33	4.00e-171	593.00
IUUC-Dme-032075	Drosophila melanogaster	32.26	3.00e-101	361.00
IUUC-Ete-032865	Echinops telfairi	31.97	1.00e-110	392.00
IUUC-Eca-034059	Equus caballus	34.31	2.00e-124	438.00
IUUC-Eeu-035304	Erinaceus europaeus	36.34	3.00e-116	410.00
IUUC-Fca-035515	Felis catus	34.28	3.00e-126	444.00
IUUC-Fal-037271	Ficedula albicollis	36.49	1.00e-123	435.00
IUUC-Fox-037745	Fusarium oxysporum	44.49	0.00e+00	637.00
IUUC-Fso-038158	Fusarium solani	46.09	0.00e+00	649.00
IUUC-Gmo-039071	Gadus morhua	34.89	2.00e-112	398.00
IUUC-Ggr-040098	Gaeumannomyces graminis	43.98	5.00e-175	606.00
IUUC-Gga-040635	Gallus gallus	34.96	6.00e-133	466.00
IUUC-Gac-042528	Gasterosteus aculeatus	34.65	1.00e-114	405.00
IUUC-Gma-043614	Glycine max	32.10	5.00e-101	360.00
IUUC-Ggo-044602	Gorilla gorilla	34.54	2.00e-126	444.00
IUUC-Hsa-045959	Homo sapiens	34.54	2.00e-126	444.00
IUUC-Hvu-047563	Hordeum vulgare	35.51	3.00e-94	337.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	34.35	1.00e-126	445.00
IUUC-Kpa-049156	Komagataella pastoris	37.50	4.00e-148	516.00
IUUC-Lch-049648	Latimeria chalumnae	34.00	2.00e-120	425.00
IUUC-Lpe-051523	Leersia perrieri	31.78	1.00e-96	345.00
IUUC-Loc-052072	Lepisosteus oculatus	32.53	2.00e-111	394.00
IUUC-Lma-053216	Leptosphaeria maculans	46.31	7.00e-177	613.00
IUUC-Laf-054327	Loxodonta africana	34.35	3.00e-125	441.00
IUUC-Mcc-055443	Macaca mulatta	34.43	4.00e-125	440.00
IUUC-Meu-056298	Macropus eugenii	34.59	1.00e-81	296.00
IUUC-Mor-057106	Magnaporthe oryzae	44.23	0.00e+00	633.00
IUUC-Mpo-057589	Magnaporthe poae	43.86	1.00e-174	605.00
IUUC-Mtr-058680	Medicago truncatula	33.81	3.00e-109	387.00
IUUC-Mla-058903	Melampsora laricipopulina	45.70	0.00e+00	679.00
IUUC-Mga-059669	Meleagris gallopavo	35.03	3.00e-125	441.00
IUUC-Mmr-060575	Microcebus murinus	34.39	2.00e-126	444.00
IUUC-Mdo-062183	Monodelphis domestica	33.94	8.00e-125	439.00
IUUC-Mmu-063592	Mus musculus	34.39	3.00e-127	447.00
IUUC-Mac-065446	Musa acuminata	31.41	1.00e-91	329.00
IUUC-Mpu-066082	Mustela putorius furo	34.97	8.00e-128	449.00
IUUC-Mlu-067345	Myotis lucifugus	33.94	6.00e-126	443.00
IUUC-Nfi-068558	Neosartorya fischeri	43.54	3.00e-167	580.00
IUUC-Ncr-068960	Neurospora crassa	44.13	4.00e-176	610.00
IUUC-Nle-070173	Nomascus leucogenys	34.50	4.00e-128	450.00
IUUC-Opr-070556	Ochotona princeps	34.46	7.00e-126	443.00
IUUC-Ont-071502	Oreochromis niloticus	35.35	1.00e-117	415.00
IUUC-Oan-072959	Ornithorhynchus anatinus	43.23	2.00e-42	163.00
IUUC-Ocu-074861	Oryctolagus cuniculus	35.27	1.00e-128	452.00
IUUC-Oba-075109	Oryza barthii	32.46	1.00e-101	362.00
IUUC-Obr-076292	Oryza brachyantha	33.53	4.00e-101	360.00
IUUC-Ogl-077065	Oryza glaberrima	33.37	9.00e-107	379.00
IUUC-Ogu-078776	Oryza glumaepatula	31.98	7.00e-103	366.00
IUUC-Oin-080048	Oryza indica	32.78	1.00e-104	372.00
IUUC-Olo-080711	Oryza longistaminata	31.91	5.00e-93	333.00
IUUC-Ome-081506	Oryza meridionalis	32.48	2.00e-94	338.00
IUUC-Oni-082320	Oryza nivara	31.71	1.00e-98	352.00
IUUC-Opu-083801	Oryza punctata	32.66	2.00e-96	345.00
IUUC-Oru-085139	Oryza rufipogon	31.94	1.00e-99	355.00
IUUC-Osa-085713	Oryza sativa	33.49	6.00e-108	383.00
IUUC-Ola-086951	Oryzias latipes	34.05	1.00e-110	392.00
IUUC-Olu-087822	Ostreococcus lucimarinus	32.66	1.00e-95	342.00
IUUC-Oga-088625	Otolemur garnettii	34.05	8.00e-126	442.00
IUUC-Oar-089995	Ovis aries	34.21	2.00e-126	445.00
IUUC-Ptr-090640	Pan troglodytes	35.06	4.00e-128	450.00
IUUC-Pan-091974	Papio anubis	34.20	3.00e-125	441.00
IUUC-Psi-093957	Pelodiscus sinensis	34.89	4.00e-132	464.00
IUUC-Pma-094242	Petromyzon marinus	38.58	2.00e-71	261.00
IUUC-Pno-094835	Phaeosphaeria nodorum	43.06	2.00e-149	521.00
IUUC-Ppa-095901	Physcomitrella patens	33.65	1.00e-111	395.00
IUUC-Pfo-097148	Poecilia formosa	35.16	8.00e-116	409.00
IUUC-Pab-098068	Pongo abelii	32.08	2.00e-113	402.00
IUUC-Pop-098855	Populus trichocarpa	32.27	2.00e-103	369.00
IUUC-Pca-100738	Procavia capensis	35.97	1.00e-98	352.00
IUUC-Ppe-101315	Prunus persica	31.82	2.00e-99	355.00
IUUC-Pva-102154	Pteropus vampyrus	34.58	2.00e-126	445.00
IUUC-Pgr-103343	Puccinia graminis	45.63	1.00e-154	538.00
IUUC-Ptt-103928	Puccinia triticina	40.19	1.00e-149	522.00
IUUC-Pte-104306	Pyrenophora teres	45.11	6.00e-169	586.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	45.23	1.00e-172	598.00
IUUC-Rno-105801	Rattus norvegicus	34.80	3.00e-127	447.00
IUUC-Sce-106304	Saccharomyces cerevisiae	31.86	3.00e-100	358.00
IUUC-Sha-107635	Sarcophilus harrisii	34.84	3.00e-127	447.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	40.28	6.00e-157	546.00
IUUC-Spo-108144	Schizosaccharomyces pombe	41.64	7.00e-166	575.00
IUUC-Smo-108848	Selaginella moellendorffii	34.23	2.00e-110	391.00
IUUC-Sit-110728	Setaria italica	32.16	5.00e-105	374.00
IUUC-Sly-111523	Solanum lycopersicum	34.68	1.00e-114	405.00
IUUC-Sar-113733	Sorex araneus	40.79	1.00e-54	206.00
IUUC-Sbi-114419	Sorghum bicolor	32.46	3.00e-105	374.00
IUUC-Sre-115225	Sporisorium reilianum	47.61	0.00e+00	677.00
IUUC-Ssc-115686	Sus scrofa	34.17	2.00e-126	444.00
IUUC-Tgu-117346	Taeniopygia guttata	34.92	1.00e-126	446.00
IUUC-Tru-118350	Takifugu rubripes	32.99	1.00e-109	389.00
IUUC-Tsy-119278	Tarsius syrichta	34.46	4.00e-88	317.00
IUUC-Tni-120658	Tetraodon nigroviridis	33.52	9.00e-109	386.00
IUUC-Tca-121585	Theobroma cacao	32.98	6.00e-106	376.00
IUUC-Tre-122043	Trichoderma reesei	43.21	3.00e-173	600.00
IUUC-Tvi-122303	Trichoderma virens	43.27	2.00e-179	621.00
IUUC-Tae-125686	Triticum aestivum	32.33	3.00e-102	364.00
IUUC-Tur-126732	Triticum urartu	30.94	3.00e-93	334.00
IUUC-Tme-126909	Tuber melanosporum	44.57	2.00e-175	607.00
IUUC-Tbe-127261	Tupaia belangeri	31.74	2.00e-51	196.00
IUUC-Ttr-129119	Tursiops truncatus	35.17	7.00e-52	197.00
IUUC-Uma-129599	Ustilago maydis	46.81	0.00e+00	702.00
IUUC-Vda-129688	Verticillium dahliae	44.15	4.00e-177	613.00
IUUC-Vpa-130170	Vicugna pacos	28.59	5.00e-68	250.00
IUUC-Vvi-131116	Vitis vinifera	33.45	5.00e-104	370.00
IUUC-Xtr-131953	Xenopus tropicalis	34.09	5.00e-112	397.00
IUUC-Xma-133837	Xiphophorus maculatus	35.16	3.00e-116	410.00
IUUC-Yli-134510	Yarrowia lipolytica	41.66	5.00e-148	516.00
IUUC-Zma-135786	Zea mays	33.10	6.00e-98	350.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence