iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073256

Ensembl Protein ID

ENSOANP00000006480.2

UniProt Accession

F6S7P6; F6S7P6_ORNAN

Protein Name

Uncharacterized protein

Gene Name

PACSIN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000004082.2	ENSOANT00000006482.2	ENSOANP00000006480.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.60e-14	53.8	369	424

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +v++lydy++q+ deL++++G+ +l +  ee ++gW++g+   +g+ Gl P+n+ve +
   Q: 369  RVRALYDYSGQEADELSFRAGEELLKM-SEEDEQGWCQGQ-LQSGRVGLYPANYVECV 424
           699********************9999.999********7.99************976 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MAPEDDTGGE APGGSFWEAG HYRRTVQRVE DGHRLCGDLV NCFQERARIE KAYAQQLADW 60
ARKWRSAVEK GPQYGTLEKA WHAFLTAAER LSALHLEVRE RLQGEDSERV RAWQREAFHR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGCCCGGGA CTCGGCCACC ATTCCGTGCT GCAGGGACAA AATGGCCCCG GAGGACGACA 60
CCGGAGGGGA GGCCCCCGGG GGCAGCTTCT GGGAGGTGAG GAGTGGCGGA GAGGACGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR028523--PACSIN3
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0019855--F:calcium channel inhibitor activity
GO:0008289--F:lipid binding
GO:0051926--P:negative regulation of calcium ion transport
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0051044--P:positive regulation of membrane protein ectodomain proteolysis
GO:0030100--P:regulation of endocytosis

KEGG

oaa:100089623

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001906	Ailuropoda melanoleuca	87.99	1.00e-175	608.00
IUUC-Apl-003211	Anas platyrhynchos	65.94	0.00e+00	635.00
IUUC-Aca-004256	Anolis carolinensis	65.36	2.00e-180	624.00
IUUC-Ame-011049	Astyanax mexicanus	61.05	4.00e-157	546.00
IUUC-Bta-013322	Bos taurus	85.68	0.00e+00	730.00
IUUC-Cel-018168	Caenorhabditis elegans	31.25	3.00e-44	172.00
IUUC-Cja-018907	Callithrix jacchus	87.79	0.00e+00	753.00
IUUC-Cfa-021126	Canis familiaris	87.32	0.00e+00	745.00
IUUC-Cpo-021491	Cavia porcellus	87.56	0.00e+00	755.00
IUUC-Csa-023107	Chlorocebus sabaeus	89.20	0.00e+00	760.00
IUUC-Cin-025707	Ciona intestinalis	41.67	2.00e-96	345.00
IUUC-Dre-027933	Danio rerio	60.66	2.00e-150	524.00
IUUC-Dno-029002	Dasypus novemcinctus	87.32	0.00e+00	718.00
IUUC-Dme-032120	Drosophila melanogaster	42.81	5.00e-76	277.00
IUUC-Eca-033824	Equus caballus	87.09	0.00e+00	750.00
IUUC-Eeu-035122	Erinaceus europaeus	79.44	2.00e-162	564.00
IUUC-Fca-036420	Felis catus	87.56	0.00e+00	771.00
IUUC-Fal-037277	Ficedula albicollis	65.86	0.00e+00	637.00
IUUC-Gmo-039681	Gadus morhua	51.26	2.00e-116	411.00
IUUC-Gga-040941	Gallus gallus	66.30	0.00e+00	632.00
IUUC-Gac-041374	Gasterosteus aculeatus	62.44	6.00e-143	499.00
IUUC-Ggo-045211	Gorilla gorilla	88.73	0.00e+00	757.00
IUUC-Hsa-046053	Homo sapiens	89.20	0.00e+00	760.00
IUUC-Itr-047939	Ictidomys tridecemlineatus	87.56	0.00e+00	753.00
IUUC-Lch-050070	Latimeria chalumnae	48.10	8.00e-121	426.00
IUUC-Loc-052808	Lepisosteus oculatus	62.11	5.00e-160	556.00
IUUC-Laf-054211	Loxodonta africana	86.15	0.00e+00	716.00
IUUC-Mcc-055044	Macaca mulatta	89.20	0.00e+00	760.00
IUUC-Meu-056348	Macropus eugenii	53.26	1.00e-118	419.00
IUUC-Mga-059216	Meleagris gallopavo	66.23	0.00e+00	633.00
IUUC-Mmr-061172	Microcebus murinus	88.03	0.00e+00	761.00
IUUC-Mdo-062600	Monodelphis domestica	88.03	0.00e+00	781.00
IUUC-Mmu-063218	Mus musculus	85.92	0.00e+00	739.00
IUUC-Mpu-066819	Mustela putorius furo	75.45	0.00e+00	726.00
IUUC-Mlu-067597	Myotis lucifugus	85.15	0.00e+00	755.00
IUUC-Nle-069195	Nomascus leucogenys	88.73	0.00e+00	755.00
IUUC-Opr-071050	Ochotona princeps	87.79	0.00e+00	743.00
IUUC-Ont-072188	Oreochromis niloticus	50.47	2.00e-123	434.00
IUUC-Ocu-074653	Oryctolagus cuniculus	87.09	0.00e+00	721.00
IUUC-Ola-087188	Oryzias latipes	51.24	9.00e-109	386.00
IUUC-Oga-089040	Otolemur garnettii	86.85	0.00e+00	755.00
IUUC-Oar-089918	Ovis aries	88.59	0.00e+00	738.00
IUUC-Ptr-091307	Pan troglodytes	89.20	0.00e+00	760.00
IUUC-Pan-092512	Papio anubis	89.20	0.00e+00	760.00
IUUC-Pfo-096881	Poecilia formosa	61.12	6.00e-156	543.00
IUUC-Pab-098620	Pongo abelii	89.20	0.00e+00	760.00
IUUC-Pca-100881	Procavia capensis	53.26	1.00e-118	419.00
IUUC-Pva-102464	Pteropus vampyrus	84.98	0.00e+00	720.00
IUUC-Rno-106091	Rattus norvegicus	85.45	0.00e+00	738.00
IUUC-Sha-107474	Sarcophilus harrisii	87.79	0.00e+00	778.00
IUUC-Ssc-116128	Sus scrofa	87.09	0.00e+00	756.00
IUUC-Tgu-117511	Taeniopygia guttata	63.37	0.00e+00	625.00
IUUC-Tru-118005	Takifugu rubripes	62.22	1.00e-146	512.00
IUUC-Tni-119851	Tetraodon nigroviridis	65.14	9.00e-145	505.00
IUUC-Ttr-129313	Tursiops truncatus	87.32	0.00e+00	765.00
IUUC-Vpa-130760	Vicugna pacos	89.62	1.00e-94	339.00
IUUC-Xtr-132697	Xenopus tropicalis	56.35	1.00e-140	491.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence