iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000003686.1	ENSOART00000004004.1	ENSOARP00000003935.1
ENSOARG00000003686.1	ENSOART00000004005.1	ENSOARP00000003936.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.50e-23	79.9	45	76

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDl 30
           gH++ v+cl++   ++ll+sGsdD    vWD+
   Q: 45   GHSGCVNCLEWneKGDLLASGSDDQHTIVWDP 76
           8**********65339***************6 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MAKVNITRDL IRRQIKERGA LSFERRYHVT DPFIRRLGLE AELQGHSGCV NCLEWNEKGD 60
LLASGSDDQH TIVWDPLHHK KLLSMHTGHT ANIFSVKFLP HAGDRILITG AADSKVHVHD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAATTAAAT GTGTGTCTTG TGGACCTGGG CTTGGCTGGA ATGCTCAAGG GTCCTGAAGA 60
TACTTCTATA GCGTCCTTCT GTTGAACCCA TTAAGAGAAG ATGGCAAAAG TCAACATAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50293--TPR_REGION
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00028--TPR
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004857--F:enzyme inhibitor activity
GO:0055082--P:cellular chemical homeostasis
GO:0032869--P:cellular response to insulin stimulus
GO:0006006--P:glucose metabolic process
GO:0001701--P:in utero embryonic development
GO:0035264--P:multicellular organism growth
GO:0045717--P:negative regulation of fatty acid biosynthetic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008361--P:regulation of cell size

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000083	Aegilops tauschii	28.70	4.00e-51	196.00
IUUC-Aml-001699	Ailuropoda melanoleuca	96.91	0.00e+00	1314.00
IUUC-Atr-002509	Amborella trichopoda	31.31	1.00e-50	194.00
IUUC-Apl-003379	Anas platyrhynchos	91.45	0.00e+00	1246.00
IUUC-Aca-005202	Anolis carolinensis	88.66	0.00e+00	1218.00
IUUC-Aly-006475	Arabidopsis lyrata	31.49	6.00e-54	205.00
IUUC-Ath-007666	Arabidopsis thaliana	31.15	3.00e-53	203.00
IUUC-Ani-009263	Aspergillus nidulans	27.35	3.00e-25	110.00
IUUC-Ang-009671	Aspergillus niger	27.32	2.00e-26	115.00
IUUC-Ame-010988	Astyanax mexicanus	79.87	0.00e+00	972.00
IUUC-Bdi-014100	Brachypodium distachyon	30.17	5.00e-50	192.00
IUUC-Bol-016409	Brassica oleracea	31.32	2.00e-51	197.00
IUUC-Bra-016979	Brassica rapa	31.41	3.00e-51	197.00
IUUC-Cel-018561	Caenorhabditis elegans	41.38	5.00e-28	119.00
IUUC-Cja-019212	Callithrix jacchus	94.69	0.00e+00	1263.00
IUUC-Cfa-020200	Canis familiaris	96.91	0.00e+00	1313.00
IUUC-Cpo-021739	Cavia porcellus	97.64	0.00e+00	1315.00
IUUC-Cre-022659	Chlamydomonas reinhardtii	33.85	2.00e-34	140.00
IUUC-Csa-023648	Chlorocebus sabaeus	97.20	0.00e+00	1311.00
IUUC-Cin-025155	Ciona intestinalis	44.56	2.00e-63	236.00
IUUC-Csv-026289	Ciona savignyi	44.72	1.00e-137	483.00
IUUC-Cme-027316	Cyanidioschyzon merolae	27.99	4.00e-26	113.00
IUUC-Dre-028745	Danio rerio	78.91	0.00e+00	1079.00
IUUC-Dno-029403	Dasypus novemcinctus	90.86	0.00e+00	1220.00
IUUC-Dor-030332	Dipodomys ordii	86.60	0.00e+00	1182.00
IUUC-Dme-031811	Drosophila melanogaster	36.77	3.00e-102	366.00
IUUC-Ete-032331	Echinops telfairi	91.76	1.00e-146	513.00
IUUC-Eca-033783	Equus caballus	96.47	0.00e+00	1313.00
IUUC-Eeu-034732	Erinaceus europaeus	94.40	0.00e+00	1262.00
IUUC-Fca-036543	Felis catus	96.91	0.00e+00	1314.00
IUUC-Fal-037245	Ficedula albicollis	90.79	0.00e+00	1258.00
IUUC-Gmo-039346	Gadus morhua	77.32	0.00e+00	1085.00
IUUC-Gga-041034	Gallus gallus	91.30	0.00e+00	1241.00
IUUC-Gac-041297	Gasterosteus aculeatus	78.35	0.00e+00	1077.00
IUUC-Gma-042727	Glycine max	31.62	9.00e-50	191.00
IUUC-Ggo-045309	Gorilla gorilla	97.20	0.00e+00	1311.00
IUUC-Hsa-046622	Homo sapiens	97.20	0.00e+00	1311.00
IUUC-Itr-049052	Ictidomys tridecemlineatus	95.81	0.00e+00	1130.00
IUUC-Lch-049810	Latimeria chalumnae	84.14	0.00e+00	1125.00
IUUC-Lpe-051600	Leersia perrieri	26.54	2.00e-60	226.00
IUUC-Loc-052088	Lepisosteus oculatus	83.92	0.00e+00	1153.00
IUUC-Laf-054097	Loxodonta africana	96.31	0.00e+00	1308.00
IUUC-Mcc-054848	Macaca mulatta	97.20	0.00e+00	1311.00
IUUC-Meu-056022	Macropus eugenii	71.43	0.00e+00	773.00
IUUC-Mtr-057735	Medicago truncatula	30.88	4.00e-47	182.00
IUUC-Mga-059622	Meleagris gallopavo	91.30	0.00e+00	1243.00
IUUC-Mmr-060709	Microcebus murinus	96.76	0.00e+00	1313.00
IUUC-Mdo-062401	Monodelphis domestica	94.10	0.00e+00	1269.00
IUUC-Mmu-063899	Mus musculus	95.13	0.00e+00	1286.00
IUUC-Mac-064840	Musa acuminata	31.30	5.00e-49	189.00
IUUC-Mpu-066268	Mustela putorius furo	96.76	0.00e+00	1311.00
IUUC-Mlu-067211	Myotis lucifugus	98.54	0.00e+00	852.00
IUUC-Nle-070019	Nomascus leucogenys	97.05	0.00e+00	1289.00
IUUC-Opr-071008	Ochotona princeps	96.31	0.00e+00	1311.00
IUUC-Ont-072123	Oreochromis niloticus	79.53	0.00e+00	1104.00
IUUC-Ocu-074166	Oryctolagus cuniculus	96.46	0.00e+00	1312.00
IUUC-Oba-075298	Oryza barthii	29.05	1.00e-42	167.00
IUUC-Obr-076849	Oryza brachyantha	33.77	5.00e-37	149.00
IUUC-Ogl-077515	Oryza glaberrima	29.05	9.00e-43	168.00
IUUC-Ogu-077968	Oryza glumaepatula	29.05	1.00e-38	154.00
IUUC-Oin-079231	Oryza indica	28.60	1.00e-37	151.00
IUUC-Olo-081045	Oryza longistaminata	34.40	1.00e-31	132.00
IUUC-Ome-081395	Oryza meridionalis	29.17	4.00e-37	149.00
IUUC-Oni-082801	Oryza nivara	28.52	2.00e-42	167.00
IUUC-Opu-083585	Oryza punctata	29.12	1.00e-42	168.00
IUUC-Oru-085163	Oryza rufipogon	33.77	2.00e-36	147.00
IUUC-Osa-085550	Oryza sativa	33.60	8.00e-29	120.00
IUUC-Ola-086925	Oryzias latipes	77.03	0.00e+00	1063.00
IUUC-Oga-088095	Otolemur garnettii	95.58	0.00e+00	1309.00
IUUC-Ptr-091221	Pan troglodytes	97.20	0.00e+00	1311.00
IUUC-Pan-091771	Papio anubis	97.20	0.00e+00	1311.00
IUUC-Psi-093977	Pelodiscus sinensis	90.27	0.00e+00	1232.00
IUUC-Ppa-095373	Physcomitrella patens	30.41	2.00e-48	187.00
IUUC-Pfo-096640	Poecilia formosa	78.91	0.00e+00	1085.00
IUUC-Pab-098513	Pongo abelii	97.20	0.00e+00	1311.00
IUUC-Pop-098837	Populus trichocarpa	31.12	2.00e-45	177.00
IUUC-Pca-101095	Procavia capensis	87.61	0.00e+00	1156.00
IUUC-Ppe-101507	Prunus persica	30.06	4.00e-48	186.00
IUUC-Pva-102444	Pteropus vampyrus	97.49	0.00e+00	1316.00
IUUC-Rno-105952	Rattus norvegicus	94.99	0.00e+00	1285.00
IUUC-Sha-106614	Sarcophilus harrisii	94.40	0.00e+00	1280.00
IUUC-Smo-108844	Selaginella moellendorffii	32.57	4.00e-46	179.00
IUUC-Sit-110154	Setaria italica	28.93	2.00e-46	180.00
IUUC-Sly-111707	Solanum lycopersicum	31.75	4.00e-49	189.00
IUUC-Sar-113129	Sorex araneus	87.70	0.00e+00	882.00
IUUC-Sbi-113858	Sorghum bicolor	28.85	1.00e-60	227.00
IUUC-Ssc-116275	Sus scrofa	97.79	0.00e+00	1318.00
IUUC-Tgu-117507	Taeniopygia guttata	91.30	0.00e+00	1246.00
IUUC-Tru-117969	Takifugu rubripes	77.17	0.00e+00	1087.00
IUUC-Tsy-119374	Tarsius syrichta	86.79	0.00e+00	862.00
IUUC-Tni-119887	Tetraodon nigroviridis	75.80	0.00e+00	1035.00
IUUC-Tca-121722	Theobroma cacao	32.53	2.00e-49	191.00
IUUC-Tae-124583	Triticum aestivum	30.20	1.00e-42	168.00
IUUC-Tur-125968	Triticum urartu	35.34	3.00e-33	138.00
IUUC-Tme-126910	Tuber melanosporum	34.26	2.00e-24	107.00
IUUC-Tbe-127511	Tupaia belangeri	91.72	2.00e-90	325.00
IUUC-Ttr-128390	Tursiops truncatus	94.55	0.00e+00	1260.00
IUUC-Uma-129509	Ustilago maydis	27.18	2.00e-13	71.20
IUUC-Vpa-130124	Vicugna pacos	59.11	1.00e-147	516.00
IUUC-Vvi-131565	Vitis vinifera	29.08	1.00e-34	142.00
IUUC-Xtr-132290	Xenopus tropicalis	75.95	0.00e+00	1023.00
IUUC-Xma-134025	Xiphophorus maculatus	78.47	0.00e+00	1080.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence