iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034425

UUCD1 version

UUC-EqC-00151

Ensembl Protein ID

ENSECAP00000018860.1

UniProt Accession

F6S4Z7; F6S4Z7_HORSE

Protein Name

Uncharacterized protein

Gene Name

POC1A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000021302.1	ENSECAT00000022802.1	ENSECAP00000018860.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.00e-58	190.6	164	202
UBD/Beta-Prp	1.10e-75	254.8	37	244

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H ++v+c +f +d +l+vs+sdD+t+k+WD ++  +++s
   Q: 164  HINWVRCAKFsPDgRLIVSASDDKTVKLWDKTSRECVHS 202
           999********999******************9999886 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
           kg h + +tcv+fs ++++l +gs+d+++ +w +++++   +  gh+++vt+v+fsp+g +l++gs+D+t+++w ++      ++++h+
   Q: 37   KG-HRDAVTCVDFSFNTKQLGSGSMDSCLMLWHMKPQSRAYR-FGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHT 123
           44.5557788**************************998444.69*****************************7775555667899** PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsv 183
           ++v+s++f+ +g++lv++s+d+t++vw ++ ++ l   ls+h  +v+c++++pdg+l+vs+s+D+tv+lWd  + ++++   + h + v
   Q: 124  ATVRSVHFCSDGQSLVTASDDKTVKVWSTHRQKFLF-SLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKTSRECVHSYCE-HGSFV 210
           ***************************999999999.********************************************98.***** PP
   S: 184  yslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
           + ++f+++g++++++s+d+tvk+wd++t + ++ +
   Q: 211  TYVDFHPSGTCIAAASMDNTVKVWDVRTHR-LQHY 244
           **************************9986.5555 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

AVIGRVLAPG KPLPHPGFTH LTLALPQEDP SLERHFKGHR DAVTCVDFSF NTKQLGSGSM 60
DSCLMLWHMK PQSRAYRFGH KDAVTCVNFS PSGHLLASGS RDKTVRIWVP NVKGESTVFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGTTATAG GAAGAGTCTT GGCCCCGGGG AAGCCCCTGC CTCATCCAGG CTTCACACAT 60
TTGACCTTGG CTCTCCCCCA GGAGGACCCC TCATTGGAGA GGCATTTTAA GGGCCACCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000922--C:spindle pole
GO:0003431--P:growth plate cartilage chondrocyte development
GO:0007052--P:mitotic spindle organization
GO:1905515--P:non-motile cilium assembly
GO:0010825--P:positive regulation of centrosome duplication
GO:0007283--P:spermatogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001513	Ailuropoda melanoleuca	94.65	0.00e+00	768.00
IUUC-Apl-003466	Anas platyrhynchos	77.75	0.00e+00	640.00
IUUC-Aca-004323	Anolis carolinensis	71.23	8.00e-179	619.00
IUUC-Bta-012484	Bos taurus	93.27	0.00e+00	776.00
IUUC-Cja-019067	Callithrix jacchus	92.11	0.00e+00	819.00
IUUC-Cfa-020439	Canis familiaris	94.76	0.00e+00	781.00
IUUC-Cpo-021403	Cavia porcellus	89.34	0.00e+00	786.00
IUUC-Cre-022724	Chlamydomonas reinhardtii	51.40	6.00e-110	390.00
IUUC-Csa-023479	Chlorocebus sabaeus	92.95	0.00e+00	685.00
IUUC-Cho-024354	Choloepus hoffmanni	85.45	4.00e-109	386.00
IUUC-Cin-025258	Ciona intestinalis	71.10	5.00e-138	484.00
IUUC-Csv-025955	Ciona savignyi	63.06	6.00e-142	496.00
IUUC-Dno-029467	Dasypus novemcinctus	78.05	2.00e-124	438.00
IUUC-Dor-030399	Dipodomys ordii	89.93	0.00e+00	752.00
IUUC-Dme-032182	Drosophila melanogaster	46.00	2.00e-77	282.00
IUUC-Eeu-034607	Erinaceus europaeus	81.33	0.00e+00	631.00
IUUC-Fca-035627	Felis catus	95.26	0.00e+00	761.00
IUUC-Fal-037381	Ficedula albicollis	74.81	1.00e-180	625.00
IUUC-Gmo-038489	Gadus morhua	67.84	1.00e-158	551.00
IUUC-Gga-040559	Gallus gallus	73.62	3.00e-175	607.00
IUUC-Gac-041453	Gasterosteus aculeatus	69.04	2.00e-168	584.00
IUUC-Ggo-044773	Gorilla gorilla	92.38	0.00e+00	745.00
IUUC-Hsa-045823	Homo sapiens	92.87	0.00e+00	750.00
IUUC-Itr-048560	Ictidomys tridecemlineatus	94.03	0.00e+00	790.00
IUUC-Lch-050558	Latimeria chalumnae	68.37	5.00e-173	600.00
IUUC-Loc-052836	Lepisosteus oculatus	68.36	3.00e-174	604.00
IUUC-Laf-053974	Loxodonta africana	84.11	0.00e+00	673.00
IUUC-Mcc-055494	Macaca mulatta	90.91	0.00e+00	751.00
IUUC-Meu-056646	Macropus eugenii	74.15	4.00e-124	437.00
IUUC-Mga-059295	Meleagris gallopavo	66.89	1.00e-169	588.00
IUUC-Mmr-061040	Microcebus murinus	94.26	0.00e+00	781.00
IUUC-Mdo-062519	Monodelphis domestica	78.38	1.00e-174	605.00
IUUC-Mmu-063759	Mus musculus	93.33	1.00e-168	585.00
IUUC-Mpu-066442	Mustela putorius furo	94.51	0.00e+00	754.00
IUUC-Mlu-068163	Myotis lucifugus	90.60	0.00e+00	771.00
IUUC-Nle-070160	Nomascus leucogenys	93.27	0.00e+00	749.00
IUUC-Opr-070192	Ochotona princeps	90.59	0.00e+00	666.00
IUUC-Ont-072539	Oreochromis niloticus	71.87	5.00e-147	514.00
IUUC-Oan-072834	Ornithorhynchus anatinus	60.93	5.00e-109	387.00
IUUC-Ocu-074624	Oryctolagus cuniculus	91.87	0.00e+00	704.00
IUUC-Ola-087268	Oryzias latipes	62.65	2.00e-157	548.00
IUUC-Oga-088964	Otolemur garnettii	86.55	0.00e+00	733.00
IUUC-Oar-090202	Ovis aries	93.65	0.00e+00	785.00
IUUC-Ptr-091164	Pan troglodytes	93.53	0.00e+00	751.00
IUUC-Pan-092805	Papio anubis	92.41	0.00e+00	681.00
IUUC-Psi-093359	Pelodiscus sinensis	82.87	3.00e-162	564.00
IUUC-Pma-094425	Petromyzon marinus	76.13	1.00e-146	512.00
IUUC-Ppa-095677	Physcomitrella patens	45.60	1.00e-77	282.00
IUUC-Pfo-096741	Poecilia formosa	58.55	6.00e-152	530.00
IUUC-Pab-098376	Pongo abelii	93.52	0.00e+00	786.00
IUUC-Pca-101122	Procavia capensis	88.70	0.00e+00	739.00
IUUC-Pva-103104	Pteropus vampyrus	73.82	4.00e-165	573.00
IUUC-Rno-105282	Rattus norvegicus	87.84	0.00e+00	657.00
IUUC-Sha-106840	Sarcophilus harrisii	80.83	7.00e-114	402.00
IUUC-Smo-108731	Selaginella moellendorffii	43.81	2.00e-74	272.00
IUUC-Sar-113262	Sorex araneus	73.97	2.00e-133	468.00
IUUC-Ssc-115392	Sus scrofa	91.60	0.00e+00	683.00
IUUC-Tgu-117340	Taeniopygia guttata	74.50	8.00e-176	609.00
IUUC-Tru-117577	Takifugu rubripes	72.19	5.00e-134	471.00
IUUC-Tsy-119404	Tarsius syrichta	86.53	0.00e+00	709.00
IUUC-Tni-120713	Tetraodon nigroviridis	70.78	3.00e-133	468.00
IUUC-Tbe-127788	Tupaia belangeri	72.85	4.00e-154	537.00
IUUC-Ttr-128608	Tursiops truncatus	88.53	0.00e+00	702.00
IUUC-Xtr-132720	Xenopus tropicalis	62.39	1.00e-156	546.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence